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Select item 88764061.

Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis

Yae-Huei Liou, Jean Personnaz, David Jacobi, Nelson H. Knudsen, Mayer M. Chalom, Kyle A. Starost, Israel C. Nnah, Chih-Hao Lee

JCI Insight. 2022 Feb 22; 7(4): e150041. Published online 2022 Feb 22. doi: 10.1172/jci.insight.150041

PMCID:: PMC8876406

Abstract Article PDF–3.6M

Select item 70978202.

Fis1 deficiencies differentially affect mitochondrial quality in skeletal muscle

Zhe Zhang, Danielle A. Sliter, Christopher K. E. Bleck, Shuzhe Ding

Mitochondrion. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Mitochondrion. 2019 Nov; 49: 217–226. Published online 2019 Sep 14. doi: 10.1016/j.mito.2019.09.005

PMCID:: PMC7097820

Abstract Article PDF–2.0M

Select item 103569173.

Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction

Luis Rios, Suman Pokhrel, Sin-Jin Li, Gwangbeom Heo, Bereketeab Haileselassie, Daria Mochly-Rosen

Nat Commun. 2023; 14: 4356. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40043-0

PMCID:: PMC10356917

Abstract Article PDF–2.7M

Select item 91330534.

Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance

Riddhita Mukherjee, Carly M. Tompkins, Nicolai Patrick Ostberg, Amit U. Joshi, Liliana M. Massis, Vijith Vijayan, Kanika Gera, Denise Monack, Timothy T. Cornell, Mark W. Hall, Daria Mochly-Rosen, Bereketeab Haileselassie

Crit Care Med. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Crit Care Med. 2022 Jun 1; 50(6): e504–e515. Published online 2022 Jan 24. doi: 10.1097/CCM.0000000000005437

PMCID:: PMC9133053

Abstract Article PDF–1.4M

Select item 83804675.

Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation

Grigor Varuzhanyan, Mark S. Ladinsky, Shun-ichi Yamashita, Manabu Abe, Kenji Sakimura, Tomotake Kanki, David C. Chan

Development. 2021 Aug 15; 148(16): dev199686. Published online 2021 Aug 12. doi: 10.1242/dev.199686

PMCID:: PMC8380467

Abstract Article

Select item 77825356.

miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T Fueger, David Chan, Rama Natarajan

Commun Biol. 2021; 4: 30. Published online 2021 Jan 4. doi: 10.1038/s42003-020-01516-w

Correction in:: Commun Biol. 2021; 4: 175.

PMCID:: PMC7782535

Abstract Article PDF–4.6M

Select item 69489267.

Drp1/Fis1 Interaction Mediates Mitochondrial Dysfunction in Septic Cardiomyopathy

Bereketeab Haileselassie, Riddhita Mukherjee, Amit U. Joshi, Brooke A. Napier, Liliana M. Massis, Nicolai Patrick Ostberg, Bruno B. Queliconi, Denise Monack, Daniel Bernstein, Daria Mochly-Rosen

J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Jan 8.

Published in final edited form as: J Mol Cell Cardiol. 2019 May; 130: 160–169. Published online 2019 Apr 11. doi: 10.1016/j.yjmcc.2019.04.006

Correction in:: J Mol Cell Cardiol. 2023 Nov 23

PMCID:: PMC6948926

Abstract Article PDF–2.0M

Select item 68941728.

Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington’s disease.

A.U. Joshi, A.E. Ebert, B. Haileselassie, D. Mochly-Rosen

J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2019 Feb; 127: 125–133. Published online 2018 Dec 11. doi: 10.1016/j.yjmcc.2018.12.004

PMCID:: PMC6894172

Abstract Article PDF–1.5M

Select item 31760369.

Homocysteine-Mediated Modulation of Mitochondrial Dynamics in Retinal Ganglion Cells

Preethi S. Ganapathy, Richard L. Perry, Amany Tawfik, Robert M. Smith, Elizabeth Perry, Penny Roon, B. Renee Bozard, Yonju Ha, Sylvia B. Smith

Invest Ophthalmol Vis Sci. 2011 Jul; 52(8): 5551–5558. Published online 2011 Jul 25. doi: 10.1167/iovs.11-7256

PMCID:: PMC3176036

Abstract Article PDF–2.0M

Select item 640899210.

Regulation of Skeletal Muscle DRP-1 and FIS-1 Protein Expression by IL-6 Signaling

Dennis K. Fix, Brandon N. VanderVeen, Brittany R. Counts, James A. Carson

Oxid Med Cell Longev. 2019; 2019: 8908457. Published online 2019 Feb 21. doi: 10.1155/2019/8908457

PMCID:: PMC6408992

Abstract Article PDF–2.8M

Select item 512763811.

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Rebecca Rojansky, Moon-Yong Cha, David C Chan

eLife. 2016; 5: e17896. Published online 2016 Nov 17. doi: 10.7554/eLife.17896

PMCID:: PMC5127638

Abstract Article PDF–5.5M

Select item 300203312.

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

Hidenori Otera, Chunxin Wang, Megan M. Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J. Youle, Katsuyoshi Mihara

J Cell Biol. 2010 Dec 13; 191(6): 1141–1158. doi: 10.1083/jcb.201007152

PMCID:: PMC3002033

Abstract Article PDF–5.4M

Select item 358366813.

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

Oliver C. Losón, Zhiyin Song, Hsiuchen Chen, David C. Chan

Mol Biol Cell. 2013 Mar 1; 24(5): 659–667. doi: 10.1091/mbc.E12-10-0721

PMCID:: PMC3583668

Abstract Article PDF–3.1M

Select item 377975514.

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

Catherine S. Palmer, Kirstin D. Elgass, Robert G. Parton, Laura D. Osellame, Diana Stojanovski, Michael T. Ryan

J Biol Chem. 2013 Sep 20; 288(38): 27584–27593. Published online 2013 Aug 6. doi: 10.1074/jbc.M113.479873

PMCID:: PMC3779755

Abstract Article PDF–5.2M

Select item 429537915.

Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development

Takaya Ishihara, Reiko Ban-Ishihara, Maki Maeda, Yui Matsunaga, Ayaka Ichimura, Sachiko Kyogoku, Hiroki Aoki, Shun Katada, Kazuto Nakada, Masatoshi Nomura, Noboru Mizushima, Katsuyoshi Mihara, Naotada Ishihara

Mol Cell Biol. 2015 Jan; 35(1): 211–223. Prepublished online 2014 Oct 27. Published online 2014 Dec 9. doi: 10.1128/MCB.01054-14

PMCID:: PMC4295379

Abstract Article PDF–7.0M

Select item 932773716.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 901455917.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 960386018.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 343226419.

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang

Neuron. Author manuscript; available in PMC 2013 Jul 12.

Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024

PMCID:: PMC3432264

Abstract Article PDF–4.9M

Select item 538122620.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

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