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Select item 99578551.

ADA2 Deficiency Mimicking Acute Disseminated Encephalomyelitis

Lisa Ehlers, Giorgia Bucciol, KU Leuven - UZA DADA2 team, Diane Beysen, Isabelle Meyts

J Clin Immunol. 2023; 43(3): 536–539. Published online 2022 Dec 6. doi: 10.1007/s10875-022-01413-3

PMCID:: PMC9957855

Article PDF–685K

Select item 1939462.

A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription

Nickolai A. Barlev, Alexander V. Emelyanov, Paola Castagnino, Philip Zegerman, Andrew J. Bannister, Manuel A. Sepulveda, Flavie Robert, Laszlo Tora, Tony Kouzarides, Barbara K. Birshtein, Shelley L. Berger

Mol Cell Biol. 2003 Oct; 23(19): 6944–6957. doi: 10.1128/MCB.23.19.6944-6957.2003

PMCID:: PMC193946

Abstract Article PDF–690K

Select item 83171613.

Circular RNA TADA2A promotes proliferation and migration via modulating of miR-638/KIAA0101 signal in non-small cell lung cancer

Ye Zhang, Hongmin Yao, Ying Li, Lu Yang, Liang Zhang, Jinxin Chen, Yong Wang, Xia Li

Oncol Rep. 2021 Sep; 46(3): 201. Published online 2021 Jul 23. doi: 10.3892/or.2021.8152

PMCID:: PMC8317161

Abstract Article PDF–2.2M

Select item 46614124.

Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5

Anne Riss, Elisabeth Scheer, Mathilde Joint, Simon Trowitzsch, Imre Berger, László Tora

J Biol Chem. 2015 Nov 27; 290(48): 28997–29009. Published online 2015 Oct 14. doi: 10.1074/jbc.M115.668533

PMCID:: PMC4661412

Abstract Article PDF–2.1M

Select item 2317765.

Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation.

L Wang, C Mizzen, C Ying, R Candau, N Barlev, J Brownell, C D Allis, S L Berger

Mol Cell Biol. 1997 Jan; 17(1): 519–527. doi: 10.1128/mcb.17.1.519

PMCID:: PMC231776

Summary PDF–500K

Select item 1257236.

hADA3 is required for p53 activity

Ting Wang, Takahiko Kobayashi, Rishu Takimoto, Alec E. Denes, Eric L. Snyder, Wafik S. el-Deiry, Rainer K. Brachmann

EMBO J. 2001 Nov 15; 20(22): 6404–6413. doi: 10.1093/emboj/20.22.6404

PMCID:: PMC125723

Abstract Article PDF–394K

Select item 57266507.

Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes

Gizem Caliskan, Ikbal C. Baris, Ferhan Ayaydin, Melanie J. Dobson, Muge Senarisoy, Imre M. Boros, Zeki Topcu, Sevil Zencir

PLoS One. 2017; 12(12): e0189193. Published online 2017 Dec 12. doi: 10.1371/journal.pone.0189193

PMCID:: PMC5726650

Abstract Article PDF–7.1M

Select item 2321598.

Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor.

A Henriksson, T Almlöf, J Ford, I J McEwan, J A Gustafsson, A P Wright

Mol Cell Biol. 1997 Jun; 17(6): 3065–3073. doi: 10.1128/mcb.17.6.3065

PMCID:: PMC232159

Summary PDF–699K

Select item 2310389.

Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.

R Candau, P A Moore, L Wang, N Barlev, C Y Ying, C A Rosen, S L Berger

Mol Cell Biol. 1996 Feb; 16(2): 593–602. doi: 10.1128/mcb.16.2.593

PMCID:: PMC231038

Summary PDF–439K

Select item 10884810.

Repression of GCN5 Histone Acetyltransferase Activity via Bromodomain-Mediated Binding and Phosphorylation by the Ku–DNA-Dependent Protein Kinase Complex

Nickolai A. Barlev, Vladimir Poltoratsky, Tom Owen-Hughes, Carol Ying, Lin Liu, Jerry L. Workman, Shelley L. Berger

Mol Cell Biol. 1998 Mar; 18(3): 1349–1358. doi: 10.1128/mcb.18.3.1349

PMCID:: PMC108848

Abstract Article PDF–770K

Select item 13909011.

Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF

Vanessa Brès, Hideaki Tagami, Jean-Marie Péloponèse, Erwan Loret, Kuan-Teh Jeang, Yoshihiro Nakatani, Stephane Emiliani, Monsef Benkirane, Rosemary E. Kiernan

EMBO J. 2002 Dec 16; 21(24): 6811–6819. doi: 10.1093/emboj/cdf669

PMCID:: PMC139090

Abstract Article PDF–252K

Select item 11717912.

ADA3-containing complexes associate with estrogen receptor alpha

Arndt Benecke, Claudine Gaudon, Jean-Marie Garnier, Elmar vom Baur, Pierre Chambon, Régine Losson

Nucleic Acids Res. 2002 Jun 1; 30(11): 2508–2514. doi: 10.1093/nar/30.11.2508

PMCID:: PMC117179

Abstract Article PDF–286K

Select item 464156413.

SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

Arnaud R. Krebs, Krishanpal Karmodiya, Marianne Lindahl-Allen, Kevin Struhl, Làszlò Tora

Mol Cell. Author manuscript; available in PMC 2015 Nov 11.

Published in final edited form as: Mol Cell. 2011 Nov 4; 44(3): 410–423. doi: 10.1016/j.molcel.2011.08.037

PMCID:: PMC4641564

Abstract Article PDF–1.1M

Select item 403191714.

c-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation^*

Xiaohui Liu, Jerusalem Tesfai, Yvonne A. Evrard, Sharon Y. R. Dent, Ernest Martinez

J Biol Chem. Author manuscript; available in PMC 2014 May 23.

Published in final edited form as: J Biol Chem. 2003 May 30; 278(22): 20405–20412. Published online 2003 Mar 26. doi: 10.1074/jbc.M211795200

PMCID:: PMC4031917

Abstract Article PDF–2.3M

Select item 229310115.

Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage

Armin M. Gamper, Robert G. Roeder

Mol Cell Biol. 2008 Apr; 28(8): 2517–2527. Published online 2008 Feb 4. doi: 10.1128/MCB.01461-07

PMCID:: PMC2293101

Abstract Article PDF–571K

Select item 225452216.

The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activator-driven transcription and cell cycle progression

Xiao-Yong Zhang, Maya Varthi, Stephen M. Sykes, Charles Phillips, Claude Warzecha, Wenting Zhu, Anastasia Wyce, Alan W. Thorne, Shelley L. Berger, Steven B. McMahon

Mol Cell. Author manuscript; available in PMC 2009 Jan 18.

Published in final edited form as: Mol Cell. 2008 Jan 18; 29(1): 102–111. doi: 10.1016/j.molcel.2007.12.015

PMCID:: PMC2254522

Abstract Article PDF–785K

Select item 115086217.

Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration

Vikas B. Palhan, Shiming Chen, Guang-Hua Peng, Agneta Tjernberg, Armin M. Gamper, Yuxin Fan, Brian T. Chait, Albert R. La Spada, Robert G. Roeder

Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24): 8472–8477. Published online 2005 Jun 2. doi: 10.1073/pnas.0503505102

PMCID:: PMC1150862

Abstract Article PDF–543K

Select item 369318318.

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Paul D. P. Pharoah, Ya-Yu Tsai, Susan J. Ramus, Catherine M. Phelan, Ellen L. Goode, Kate Lawrenson, Melissa Price, Brooke L. Fridley, Jonathan P. Tyrer, Howard Shen, Rachel Weber, Rod Karevan, Melissa C. Larson, Honglin Song, Daniel C. Tessier, François Bacot, Daniel Vincent, Julie M. Cunningham, Joe Dennis, Ed Dicks, Australian Cancer Study, Australian Ovarian Cancer Study Group, Katja K. Aben, Hoda Anton-Culver, Natalia Antonenkova, Sebastian M. Armasu, Laura Baglietto, Elisa V. Bandera, Matthias W. Beckmann, Michael J. Birrer, Greg Bloom, Natalia Bogdanova, James D. Brenton, Louise A. Brinton, Angela Brooks-Wilson, Robert Brown, Ralf Butzow, Ian Campbell, Michael E Carney, Renato S. Carvalho, Jenny Chang-Claude, Y. Anne Chen, Zhihua Chen, Wong-Ho Chow, Mine S. Cicek, Gerhard Coetzee, Linda S. Cook, Daniel W. Cramer, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Diana Eccles, Robert Edwards, Arif B. Ekici, Peter A. Fasching, David Fenstermacher, James Flanagan, Yu-Tang Gao, Montserrat Garcia-Closas, Aleksandra Gentry-Maharaj, Graham Giles, Anxhela Gjyshi, Martin Gore, Jacek Gronwald, Qi Guo, Mari K Halle, Philipp Harter, Alexander Hein, Florian Heitz, Peter Hillemanns, Maureen Hoatlin, Estrid Høgdall, Claus K. Høgdall, Satoyo Hosono, Anna Jakubowska, Allan Jensen, Kimberly R. Kalli, Beth Y. Karlan, Linda E. Kelemen, Lambertus A. Kiemeney, Susanne Krüger Kjaer, Gottfried E. Konecny, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Nathan Lee, Janet Lee, Arto Leminen, Boon Kiong Lim, Jolanta Lissowska, Jan Lubinski, Lene Lundvall, Galina Lurie, Leon F.A.G. Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Usha Menon, Francesmary Modugno, Kirsten B. Moysich, Toru Nakanishi, Steven A. Narod, Roberta B. Ness, Heli Nevanlinna, Stefan Nickels, Houtan Noushmehr, Kunle Odunsi, Sara Olson, Irene Orlow, James Paul, Tanja Pejovic, Liisa M Pelttari, Jenny Permuth-Wey, Malcolm C Pike, Elizabeth M Poole, Xiaotao Qu, Harvey A. Risch, Lorna Rodriguez-Rodriguez, Mary Anne Rossing, Anja Rudolph, Ingo Runnebaum, Iwona K Rzepecka, Helga B. Salvesen, Ira Schwaab, Gianluca Severi, Hui Shen, Vijayalakshmi Shridhar, Xiao-Ou Shu, Weiva Sieh, Melissa C. Southey, Paul Spellman, Kazuo Tajima, Soo-Hwang Teo, Kathryn L. Terry, Pamela J Thompson, Agnieszka Timorek, Shelley S. Tworoger, Anne M. van Altena, David Van Den Berg, Ignace Vergote, Robert A. Vierkant, Allison F. Vitonis, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Elisabeth Wik, Boris Winterhoff, Yin Ling Woo, Anna H Wu, Hannah P. Yang, Wei Zheng, Argyrios Ziogas, Famida Zulkifli, Marc T. Goodman, Per Hall, Douglas F Easton, Celeste L Pearce, Andrew Berchuck, Georgia Chenevix-Trench, Edwin Iversen, Alvaro N.A. Monteiro, Simon A. Gayther, Joellen M. Schildkraut, Thomas A. Sellers

Nat Genet. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Nat Genet. 2013 Apr; 45(4): 362–370e2. doi: 10.1038/ng.2564

PMCID:: PMC3693183

Abstract Article PDF–977K

Select item 291027519.

The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates

Meritxell Orpinell, Marjorie Fournier, Anne Riss, Zita Nagy, Arnaud R Krebs, Mattia Frontini, Làszlò Tora

EMBO J. 2010 Jul 21; 29(14): 2381–2394. Published online 2010 Jun 18. doi: 10.1038/emboj.2010.125

PMCID:: PMC2910275

Abstract Article PDF–1.5M

Select item 1111559720.

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

Zita Nagy, Anne Riss, Sally Fujiyama, Arnaud Krebs, Meritxell Orpinell, Pascal Jansen, Adrian Cohen, Henk G. Stunnenberg, Shigeaki Kato, Làszlò Tora

Cell Mol Life Sci. 2010 Feb; 67(4): 611–628. Published online 2009 Nov 21. doi: 10.1007/s00018-009-0199-8

PMCID:: PMC11115597

Abstract Article PDF–816K

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