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Select item 92886211.

Clinical and Genetic Characteristics of Preeclampsia

Golovchenko O. V, Abramova M. Y, Orlova V. S, Batlutskaya I. V, Sorokina I. N

Arch Razi Inst. 2022 Feb; 77(1): 293–299. Published online 2022 Feb 28. doi: 10.22092/ARI.2021.356481.1852

PMCID:: PMC9288621

Abstract Article PDF–572K

Select item 82240592.

TBX2, a Novel Regulator of Labour

Febilla Fernando, Geertruda J.M. Veenboer, Martijn A. Oudijk, Marlies A.M. Kampman, Karst Y. Heida, Louise J.M. Lagendijk, Joris A.M. van der Post, Aldo Jongejan, Gijs B. Afink, Carrie Ris-Stalpers

Medicina (Kaunas) 2021 Jun; 57(6): 515. Published online 2021 May 21. doi: 10.3390/medicina57060515

PMCID:: PMC8224059

Abstract Article PDF–5.3M

Select item 58658083.

Effect of silencing the T-Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells

Wen-Liang Du, Qian Fang, Yue Chen, Jing-Wei Teng, Yong-Shuang Xiao, Ping Xie, Bo Jin, Jun-Qi Wang

Mol Med Rep. 2017 Nov; 16(5): 6050–6058. Published online 2017 Aug 24. doi: 10.3892/mmr.2017.7361

PMCID:: PMC5865808

Abstract Article PDF–1.8M

Select item 40518304.

TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells

Bo Zhu, Meiling Zhang, Stephanie D. Byrum, Alan J. Tackett, Judith K. Davie

Int J Cancer. Author manuscript; available in PMC 2015 Aug 15.

Published in final edited form as: Int J Cancer. 2014 Aug 15; 135(4): 785–797. Published online 2014 Jan 27. doi: 10.1002/ijc.28721

PMCID:: PMC4051830

Abstract Article PDF–1.4M

Select item 38246745.

A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance

S Wansleben, E Davis, J Peres, S Prince

Cell Death Dis. 2013 Oct; 4(10): e846. Published online 2013 Oct 10. doi: 10.1038/cddis.2013.365

PMCID:: PMC3824674

Abstract Article PDF–2.0M

Select item 98387456.

T‐box transcription factor 2 mediates antitumor immune response in cutaneous squamous cell carcinoma by regulating the expression of programmed death ligand 1

Xu Wang, Zhi Li, Yadi Sun

Skin Res Technol. 2023 Jan; 29(1): e13254. Published online 2022 Dec 7. doi: 10.1111/srt.13254

PMCID:: PMC9838745

Abstract Article PDF–1.2M

Select item 63936837.

A regulatory variant in TBX2 promoter is related to the decreased susceptibility of congenital heart disease in the Han Chinese population

Ran‐ran Zhang, Ke Cai, Lian Liu, Qian Yang, Ping Zhang, Yong‐hao Gui, Feng Wang

Mol Genet Genomic Med. 2019 Feb; 7(2): e00530. Published online 2018 Dec 7. doi: 10.1002/mgg3.530

PMCID:: PMC6393683

Abstract Article PDF–515K

Select item 61423358.

Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing

Huilin Xie, Erge Zhang, Nanchao Hong, Qihua Fu, Fen Li, Sun Chen, Yu Yu, Kun Sun

Hum Genomics. 2018; 12: 44. Published online 2018 Sep 17. doi: 10.1186/s40246-018-0176-0

PMCID:: PMC6142335

Abstract Article PDF–2.5M

Select item 49160529.

TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle

Bo Zhu, Meiling Zhang, Elizabeth M. Williams, Charles Keller, Atiya Mansoor, Judith K. Davie

Oncogene. Author manuscript; available in PMC 2016 Aug 15.

Published in final edited form as: Oncogene. 2016 Aug 11; 35(32): 4212–4224. Published online 2015 Dec 21. doi: 10.1038/onc.2015.486

PMCID:: PMC4916052

Abstract Article PDF–3.6M

Select item 340250310.

The T Box Transcription Factor TBX2 Promotes Epithelial-Mesenchymal Transition and Invasion of Normal and Malignant Breast Epithelial Cells

Bin Wang, Linsey E. Lindley, Virneliz Fernandez-Vega, Megan E. Rieger, Andrew H. Sims, Karoline J. Briegel

PLoS One. 2012; 7(7): e41355. Published online 2012 Jul 23. doi: 10.1371/journal.pone.0041355

PMCID:: PMC3402503

Abstract Article PDF–1.1M

Select item 291236111.

The Retinoblastoma Protein Modulates Tbx2 Functional Specificity

Keith W. Vance, Heather M. Shaw, Mercedes Rodriguez, Sascha Ott, Colin R. Goding

Mol Biol Cell. 2010 Aug 1; 21(15): 2770–2779. doi: 10.1091/mbc.E09-12-1029

PMCID:: PMC2912361

Abstract Article PDF–1.1M

Select item 10909512.

S. Carreira, T. J. Dexter, U. Yavuzer, D. J. Easty, C. R. Goding

Mol Cell Biol. 1998 Sep; 18(9): 5099–5108. doi: 10.1128/mcb.18.9.5099

PMCID:: PMC109095

Abstract Article PDF–797K

Select item 667757513.

TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells

N. T. Crawford, A.J. McIntyre, A. McCormick, Z. C. D'Costa, N. E. Buckley, P. B. Mullan

Oncogene. Author manuscript; available in PMC 2019 Aug 2.

Published in final edited form as: Oncogene. 2019 Jun 28; 38(31): 5971–5986. Published online 2019 Jun 28. doi: 10.1038/s41388-019-0853-z

PMCID:: PMC6677575

Abstract Article PDF–2.3M

Select item 427124514.

The Anti-proliferative Function of the TGF-β1 Signaling Pathway Involves the Repression of the Oncogenic TBX2 by Its Homologue TBX3

Jarod Li, Deeya Ballim, Mercedes Rodriguez, Rutao Cui, Colin R. Goding, Huajian Teng, Sharon Prince

J Biol Chem. 2014 Dec 19; 289(51): 35633–35643. Published online 2014 Nov 4. doi: 10.1074/jbc.M114.596411

PMCID:: PMC4271245

Abstract Article PDF–2.0M

Select item 405760415.

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

Zenobia C. D'Costa, Catherine Higgins, Chee Wee Ong, Gareth W. Irwin, David Boyle, Darragh G. McArt, Karen McCloskey, Niamh E. Buckley, Nyree T. Crawford, Lalitha Thiagarajan, James T. Murray, Richard D. Kennedy, Karl A. Mulligan, D. Paul Harkin, David J.J. Waugh, Chris J. Scott, Manuel Salto-Tellez, Richard Williams, Paul B. Mullan

Oncotarget. 2014 Mar; 5(6): 1609–1620. Published online 2014 Feb 8. doi: 10.18632/oncotarget.1707

PMCID:: PMC4057604

Abstract Article PDF–1.3M

Select item 362433916.

The Transcription Factors TBX2 and TBX3 Interact with Human Papillomavirus 16 (HPV16) L2 and Repress the Long Control Region of HPVs

Marc A. Schneider, Konstanze D. Scheffer, Timo Bund, Fatima Boukhallouk, Carsten Lambert, Cristina Cotarelo, Gert O. Pflugfelder, Luise Florin, Gilles A. Spoden

J Virol. 2013 Apr; 87(8): 4461–4474. doi: 10.1128/JVI.01803-12

PMCID:: PMC3624339

Abstract Article PDF–3.2M

Select item 624297217.

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman

Nat Commun. 2018; 9: 4866. Published online 2018 Nov 19. doi: 10.1038/s41467-018-06699-9

PMCID:: PMC6242972

Abstract Article PDF–13M

Select item 603095718.

Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder

Ning Liu, Kelly Schoch, Xi Luo, Loren D M Pena, Venkata Hemanjani Bhavana, Mary K Kukolich, Sarah Stringer, Zöe Powis, Kelly Radtke, Cameron Mroske, Kristen L Deak, Marie T McDonald, Allyn McConkie-Rosell, M Louise Markert, Peter G Kranz, Nicholas Stong, Anna C Need, David Bick, Michelle D Amaral, Elizabeth A Worthey, Shawn Levy, Undiagnosed Diseases Network (UDN), Michael F Wangler, Hugo J Bellen, Vandana Shashi, Shinya Yamamoto

Hum Mol Genet. 2018 Jul 15; 27(14): 2454–2465. Published online 2018 May 2. doi: 10.1093/hmg/ddy146

PMCID:: PMC6030957

Abstract Article PDF–849K

Select item 352765219.

TBX2 expression is regulated by PAX3 in the melanocyte lineage

Fang Liu, Juxiang Cao, Jinghu Lv, Liang Dong, Eric Pier, George X. Xu, Rui-an Wang, Zhixiang Xu, Colin Goding, Rutao Cui

Pigment Cell Melanoma Res. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Pigment Cell Melanoma Res. 2013 Jan; 26(1): 67–77. Published online 2012 Nov 21. doi: 10.1111/pcmr.12029

PMCID:: PMC3527652

Abstract Article PDF–1.1M

Select item 278532420.

Phosphorylation of Histone H3 by Protein Kinase C Signaling Plays a Critical Role in the Regulation of the Developmentally Important TBX2 Gene

Huajian Teng, Reyna Deeya Ballim, Shaheen Mowla, Sharon Prince

J Biol Chem. 2009 Sep 25; 284(39): 26368–26376. Published online 2009 Jul 24. doi: 10.1074/jbc.M109.021360

PMCID:: PMC2785324

Abstract Article PDF–1.9M

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