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Select item 108471241.

Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population

Kyungtaek Park, Ah Ra Do, Yuree Chung, Min Ji Kim, Sang Jin Rhee, Dae Hyun Yoon, Seung Ho Choi, Sung Joon Cho, Han-Na Kim, Yong Min Ahn, Sungho Won

Transl Psychiatry. 2024; 14: 80. Published online 2024 Feb 6. doi: 10.1038/s41398-024-02777-3

PMCID:: PMC10847124

Abstract Article PDF–1.3M

Select item 93431822.

TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population

Jie Peng, Fanghong Lu, Ming Zhong, Yingxin Zhao, Zhihao Wang, Wei Zhang

Dis Markers. 2022; 2022: 9717510. Published online 2022 Jul 25. doi: 10.1155/2022/9717510

PMCID:: PMC9343182

Abstract Article PDF–455K

Select item 81041733.

Novel compound heterozygous variants of TBXAS1 presenting with Ghosal hematodiaphyseal dysplasia treated with steroids

Sun Young Kim, Alexander Ing, Shunyou Gong, Kai Lee Yap, Rukhmi Bhat

Mol Genet Genomic Med. 2021 Mar; 9(3): e1494. Published online 2021 Feb 17. doi: 10.1002/mgg3.1494

PMCID:: PMC8104173

Abstract Article PDF–823K

Select item 44345994.

Functional analysis of human thromboxane synthase polymorphic variants

Chung-Ying K Chen, Elizabeth M Poole, Cornelia M Ulrich, Richard J Kulmacz, Lee-Ho Wang

Pharmacogenet Genomics. Author manuscript; available in PMC 2015 May 18.

Published in final edited form as: Pharmacogenet Genomics. 2012 Sep; 22(9): 653–658. doi: 10.1097/FPC.0b013e3283562d82

PMCID:: PMC4434599

Abstract Article PDF–1.4M

Select item 33552285.

REDUCED METHYLATION OF THE THROMBOXANE SYNTHASE GENE IS CORRELATED WITH ITS INCREASED VASCULAR EXPRESSION IN PREECLAMPSIA

Ahmad A. Mousa, Jerome F. Strauss, III, Scott W. Walsh

Hypertension. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Hypertension. 2012 Jun; 59(6): 1249–1255. Published online 2012 Apr 9. doi: 10.1161/HYPERTENSIONAHA.111.188730

PMCID:: PMC3355228

Abstract Article PDF–1.6M

Select item 30745226.

Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

Mary-Clare Cathcart, Kathy Gately, Robert Cummins, Elaine Kay, Kenneth J O'Byrne, Graham P Pidgeon

Mol Cancer. 2011; 10: 25. Published online 2011 Mar 9. doi: 10.1186/1476-4598-10-25

PMCID:: PMC3074522

Abstract Article PDF–1.8M

Select item 47909277.

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy

Chen-Hsueh Pai, Ching-Tzu Yen, Chie-Pein Chen, I-Shing Yu, Shu-Wha Lin, Shu-Rung Lin

PLoS One. 2016; 11(3): e0151617. Published online 2016 Mar 14. doi: 10.1371/journal.pone.0151617

PMCID:: PMC4790927

Abstract Article PDF–10M

Select item 37936028.

Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand

Takehiko Matsunobu, Toshiaki Okuno, Chieko Yokoyama, Takehiko Yokomizo

J Lipid Res. 2013 Nov; 54(11): 2979–2987. doi: 10.1194/jlr.M037754

PMCID:: PMC3793602

Abstract Article PDF–931K

Select item 20419219.

REACTION MECHANISMS OF 15-HYDROPEROXYEICOSATETRAENOIC ACID CATALYZED BY HUMAN PROSTACYCLIN AND THROMBOXANE SYNTHASES

Hui-Chun Yeh, Ah-Lim Tsai, Lee-Ho Wang

Arch Biochem Biophys. Author manuscript; available in PMC 2007 Oct 24.

Published in final edited form as: Arch Biochem Biophys. 2007 May 15; 461(2): 159–168. Published online 2007 Apr 11. doi: 10.1016/j.abb.2007.03.012

PMCID:: PMC2041921

Abstract Article PDF–890K

Select item 378249310.

Genome-Wide Association Analysis with Gray Matter Volume as a Quantitative Phenotype in First-Episode Treatment-Naïve Patients with Schizophrenia

Qiang Wang, Bo Xiang, Wei Deng, Junyao Wu, Mingli Li, Xiaohong Ma, Yingcheng Wang, Lijun Jiang, Grainne McAlonan, Siew E. Chua, Pak C. Sham, Xun Hu, Tao Li

PLoS One. 2013; 8(9): e75083. Published online 2013 Sep 24. doi: 10.1371/journal.pone.0075083

Correction in:: PLoS One. 2015; 10(4): e0122945.

PMCID:: PMC3782493

Abstract Article PDF–1.1M

Select item 550751411.

Genetic variants of PTGS2, TXA2R and TXAS1 are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients

Xingyang Yi, Jing Lin, Hua Luo, Chun Wang, Yingying Liu

PLoS One. 2017; 12(7): e0180704. Published online 2017 Jul 12. doi: 10.1371/journal.pone.0180704

PMCID:: PMC5507514

Abstract Article PDF–922K

Select item 350171712.

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

Jun J. Yang, Cheng Cheng, Meenakshi Devidas, Xueyuan Cao, Dario Campana, Wenjian Yang, Yiping Fan, Geoff Neale, Nancy Cox, Paul Scheet, Michael J. Borowitz, Naomi J. Winick, Paul L. Martin, W. Paul Bowman, Bruce Camitta, Gregory H. Reaman, William L. Carroll, Cheryl L. Willman, Stephen P. Hunger, William E. Evans, Ching-Hon Pui, Mignon Loh, Mary V. Relling

Blood. 2012 Nov 15; 120(20): 4197–4204. Prepublished online 2012 Sep 24. doi: 10.1182/blood-2012-07-440107

PMCID:: PMC3501717

Abstract Article

Select item 275318313.

Variation in Eicosanoid Genes, Non-fatal Myocardial Infarction and Ischemic Stroke

Rozenn N. Lemaitre, Kenneth Rice, Kristin Marciante, Joshua C. Bis, Thomas S. Lumley, Kerri L. Wiggins, Nicholas L. Smith, Susan R. Heckbert, Bruce M. Psaty

Atherosclerosis. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: Atherosclerosis. 2009 Jun; 204(2): e58–e63. Published online 2008 Nov 1. doi: 10.1016/j.atherosclerosis.2008.10.011

PMCID:: PMC2753183

Abstract Article PDF–67K

Select item 288883214.

Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians

JR Shaffer, CM Kammerer, J Dorn, RE Ferrell, L Iacoviello, M Trevisan, RP Donahue

Nutr Metab Cardiovasc Dis. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nutr Metab Cardiovasc Dis. 2011 Aug; 21(8): 546–552. Published online 2010 Mar 15. doi: 10.1016/j.numecd.2009.12.002

PMCID:: PMC2888832

Abstract Article PDF–347K

Select item 31108615.

Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes

Yutaka Suzuki, Tatsuhiko Tsunoda, Jun Sese, Hirotoshi Taira, Junko Mizushima-Sugano, Hiroko Hata, Toshio Ota, Takao Isogai, Toshihiro Tanaka, Yusuke Nakamura, Akira Suyama, Yoshiyuki Sakaki, Shinichi Morishita, Kousaku Okubo, Sumio Sugano

Genome Res. 2001 May; 11(5): 677–684. doi: 10.1101/gr.164001

PMCID:: PMC311086

Abstract Article PDF–581K

Select item 278401516.

Candidate Gene Polymorphisms for Ischemic Stroke

Mar Matarin, W. Mark Brown, Hernandez Dena, Angela Britton, Fabienne Wavrant De Vrieze, Thomas G. Brott, Robert D. Brown, Jr, Bradford B. Worrall, L. Douglas Case, Stephen J. Chanock, E. Jeffrey Metter, Luigi Ferruci, Dale Gamble, John A. Hardy, Stephen S. Rich, Andrew Singleton, James F. Meschia

Stroke. Author manuscript; available in PMC 2009 Nov 26.

Published in final edited form as: Stroke. 2009 Nov; 40(11): 3436–3442. Published online 2009 Sep 3. doi: 10.1161/STROKEAHA.109.558015

PMCID:: PMC2784015

Abstract Article PDF–214K

Select item 404112317.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 265507718.

Common Genetic Variation in Candidate Genes and Susceptibility to Sub-types of Breast Cancer

Nasim Mavaddat, Alison M Dunning, Bruce AJ Ponder, Douglas F Easton, Paul D Pharoah

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2009 Jul 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Jan; 18(1): 255–259. doi: 10.1158/1055-9965.EPI-08-0704

PMCID:: PMC2655077

Abstract Article PDF–791K

Select item 671971819.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Abstract Article PDF–1.3M

Select item 357913820.

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

James A Nathan, Hyoung Tae Kim, Lily Ting, Steven P Gygi, Alfred L Goldberg

EMBO J. 2013 Feb 20; 32(4): 552–565. Published online 2013 Jan 11. doi: 10.1038/emboj.2012.354

PMCID:: PMC3579138

Abstract Article PDF–1.5M

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