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Select item 88638321.

Hemojuvelin deficiency promotes liver mitochondrial dysfunction and predisposes mice to hepatocellular carcinoma

Abdolamir Allameh, Nico Hüttmann, Edouard Charlebois, Angeliki Katsarou, Wen Gu, Konstantinos Gkouvatsos, Elisa Pasini, Mamatha Bhat, Zoran Minic, Maxim Berezovski, Maria Guido, Carine Fillebeen, Kostas Pantopoulos

Commun Biol. 2022; 5: 153. Published online 2022 Feb 22. doi: 10.1038/s42003-022-03108-2

PMCID:: PMC8863832

Abstract Article PDF–9.9M

Select item 52934782.

Minor variant of rs 16827043 in the iron regulator hemojuvelin gene (HJV) contributes to hypertension: The TAMRISK study

Seppo T. Nikkari, Anni-Laura Visto, Kirsi M. Määttä, Tarja A. Kunnas

Medicine (Baltimore) 2017 Feb; 96(5): e6052. Published online 2017 Feb 3. doi: 10.1097/MD.0000000000006052

PMCID:: PMC5293478

Abstract Article PDF–183K

Select item 48243833.

Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis

Pachiappan Arjunan, Jaya P. Gnanaprakasam, Sudha Ananth, Michelle A. Romej, Veeranan-Karmegam Rajalakshmi, Puttur D. Prasad, Pamela M. Martin, Mariappan Gurusamy, Muthusamy Thangaraju, Yangzom D. Bhutia, Vadivel Ganapathy

Invest Ophthalmol Vis Sci. 2016 Apr; 57(4): 1612–1619. Published online 2016 Apr 5. doi: 10.1167/iovs.15-17437

PMCID:: PMC4824383

Abstract Article PDF–928K

Select item 42664784.

mRNA Regulation of Cardiac Iron Transporters and Ferritin Subunits in a Mouse Model of Iron Overload

Casey J. Brewer, Ruth I. Wood, John C. Wood

Exp Hematol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Exp Hematol. 2014 Dec; 42(12): 1059–1067. Published online 2014 Sep 16. doi: 10.1016/j.exphem.2014.09.002

PMCID:: PMC4266478

Abstract Article PDF–2.8M

Select item 40530735.

Deletion of Hemojuvelin, an Iron-Regulatory Protein, in Mice Results in Abnormal Angiogenesis and Vasculogenesis in Retina Along With Reactive Gliosis

Amany Tawfik, Jaya P. Gnana-Prakasam, Sylvia B. Smith, Vadivel Ganapathy

Invest Ophthalmol Vis Sci. 2014 Jun; 55(6): 3616–3625. Published online 2014 Jun 10. doi: 10.1167/iovs.13-13677

PMCID:: PMC4053073

Abstract Article PDF–859K

Select item 38904276.

Proteomic Analysis and Molecular Modeling Characterize the Iron-Regulatory Protein, Hemojuvelin/Repulsive Guidance Molecule c

Mahta Nili, Larry David, Johannes Elferich, Ujwal Shinde, Peter Rotwein

Biochem J. Author manuscript; available in PMC 2014 May 15.

Published in final edited form as: Biochem J. 2013 May 15; 452(1): 87–95. doi: 10.1042/BJ20121845

PMCID:: PMC3890427

Abstract Article PDF–1.8M

Select item 37104457.

Iron-mediated retinal degeneration in hemojuvelin knockout mice

Jaya P. Gnana-Prakasam, Amany Tawfik, Michelle Romej, Sudha Ananth, Pamela M. Martin, Sylvia B. Smith, Vadivel Ganapathy

Biochem J. Author manuscript; available in PMC 2013 Jul 13.

Published in final edited form as: Biochem J. 2012 Jan 15; 441(2): 599–608. doi: 10.1042/BJ20111148

PMCID:: PMC3710445

Abstract Article PDF–1.7M

Select item 33563518.

Effect of Iron Overload and Iron Deficiency on Liver Hemojuvelin Protein

Jan Krijt, Jana Frýdlová, Lenka Kukačková, Yuzo Fujikura, Petr Přikryl, Martin Vokurka, Emanuel Nečas

PLoS One. 2012; 7(5): e37391. Published online 2012 May 18. doi: 10.1371/journal.pone.0037391

PMCID:: PMC3356351

Abstract Article PDF–350K

Select item 31903419.

Liver and muscle hemojuvelin are differently glycosylated

Yuzo Fujikura, Jan Krijt, Emanuel Nečas

BMC Biochem. 2011; 12: 52. Published online 2011 Sep 21. doi: 10.1186/1471-2091-12-52

PMCID:: PMC3190341

Abstract Article PDF–1.0M

Select item 317861210.

Accelerated CCl₄-Induced Liver Fibrosis in Hjv-/- Mice, Associated with an Oxidative Burst and Precocious Profibrogenic Gene Expression

Giada Sebastiani, Kostas Gkouvatsos, Carmen Maffettone, Graziella Busatto, Maria Guido, Kostas Pantopoulos

PLoS One. 2011; 6(9): e25138. Published online 2011 Sep 22. doi: 10.1371/journal.pone.0025138

PMCID:: PMC3178612

Abstract Article PDF–761K

Select item 312295011.

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

Wenjie Chen, Franklin W. Huang, Tomasa Barrientos de Renshaw, Nancy C. Andrews

Blood. 2011 Jun 9; 117(23): 6319–6325. Prepublished online 2011 Apr 14. doi: 10.1182/blood-2010-12-327957

PMCID:: PMC3122950

Abstract Article

Select item 298886712.

Conserved Proximal Promoter Elements Control Repulsive Guidance Molecule c/Hemojuvelin Gene Transcription in Skeletal Muscle

Christopher J. Severyn, Peter Rotwein

Genomics. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Genomics. 2010 Dec; 96(6): 342–351. Published online 2010 Sep 19. doi: 10.1016/j.ygeno.2010.09.001

PMCID:: PMC2988867

Abstract Article PDF–1.2M

Select item 118054313.

A mouse model of juvenile hemochromatosis

Franklin W. Huang, Jack L. Pinkus, Geraldine S. Pinkus, Mark D. Fleming, Nancy C. Andrews

J Clin Invest. 2005 Aug 1; 115(8): 2187–2191. doi: 10.1172/JCI25049

PMCID:: PMC1180543

Abstract Article PDF–487K

Select item 1083830614.

The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity

Xue Fan Wang, Robin Vigouroux, Michal Syonov, Yuriy Baglaenko, Angeliki M. Nikolakopoulou, Dene Ringuette, Horea Rus, Peter V. DiStefano, Suzie Dufour, Alireza P. Shabanzadeh, Seunggi Lee, Bernhard K. Mueller, Jason Charish, Hidekiyo Harada, Jason E. Fish, Joan Wither, Thomas Wälchli, Jean-François Cloutier, Berislav V. Zlokovic, Peter L. Carlen, Philippe P. Monnier

Nat Commun. 2024; 15: 1037. Published online 2024 Feb 3. doi: 10.1038/s41467-024-45303-1

PMCID:: PMC10838306

Abstract Article PDF–4.4M

Select item 986490215.

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice

Edouard Charlebois, Yupeng Li, Victoria Wagner, Kostas Pantopoulos, Martin Olivier

Int J Mol Sci. 2023 Jan; 24(2): 1669. Published online 2023 Jan 14. doi: 10.3390/ijms24021669

PMCID:: PMC9864902

Abstract Article PDF–3.3M

Select item 796176216.

Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice

Jan Krijt, Jana Frýdlová, Iuliia Gurieva, Petr Přikryl, Martin Báječný, Andrea U. Steinbicker, Martin Vokurka, Jaroslav Truksa

Int J Mol Sci. 2021 Mar; 22(5): 2650. Published online 2021 Mar 6. doi: 10.3390/ijms22052650

PMCID:: PMC7961762

Abstract Article PDF–3.4M

Select item 723836817.

The functional role of hemojuvelin in acute ischemic stroke

Guang-Huar Young, Sung-Chun Tang, Vin-Cent Wu, Kuo-Chuan Wang, Jing-Yi Nong, Po-Yuan Huang, Chaur-Jong Hu, Hung-Yi Chiou, Jiann-Shing Jeng, Chung Y Hsu

J Cereb Blood Flow Metab. 2020 Jun; 40(6): 1316–1327. Published online 2019 Jul 15. doi: 10.1177/0271678X19861448