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Items: 1 to 20 of 34

1.
Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid
Yana Chen, Kyle S. McCommis, Daniel Ferguson, Angela M. Hall, Charles A. Harris, Brian N. Finck
Endocrinology. 2018 Feb; 159(2): 609–621. Published online 2017 Nov 8. doi: 10.1210/en.2017-00695
PMCID:
PMC5774852
AbstractArticle
2.
The Beneficial Metabolic Effects of Insulin Sensitizers are not Attenuated by Mitochondrial Pyruvate Carrier 2 Hypomorphism
Patrick A. Vigueira, Kyle S. McCommis, Wesley T. Hodges, George G. Schweitzer, Serena L. Cole, Lalita Oonthonpan, Eric B. Taylor, William G. McDonald, Rolf F. Kletzien, Jerry R. Colca, Brian N. Finck
Exp Physiol. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Exp Physiol. 2017 Aug 1; 102(8): 985–999. Published online 2017 Jul 10. doi: 10.1113/EP086380
PMCID:
PMC5667918
AbstractArticlePDF–912K
3.
Mitochondrial pyruvate import promotes long-term survival of antibody-secreting plasma cells
Wing Y. Lam, Amy M. Becker, Krista M. Kennerly, Rachel Wong, Jonathan D. Curtis, Elizabeth M. Llufrio, Kyle S. McCommis, Johannes Fahrmann, Hannah A. Pizzato, Ryan M. Nunley, Jieun Lee, Michael J. Wolfgang, Gary J. Patti, Brian N. Finck, Erika L. Pearce, Deepta Bhattacharya
Immunity. Author manuscript; available in PMC 2017 Jul 19.
Published in final edited form as: Immunity. 2016 Jul 19; 45(1): 60–73. Published online 2016 Jul 5. doi: 10.1016/j.immuni.2016.06.011
PMCID:
PMC4956536
AbstractArticlePDF–2.6M
4.
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice
Wesley T. Hodges, Chaowapong Jarasvaraparn, Daniel Ferguson, Kristine Griffett, Lauren E. Gill, Yana Chen, Ma. Xenia G. Ilagan, Lamees Hegazy, Bahaa Elgendy, Kevin Cho, Gary J. Patti, Kyle S. McCommis, Brian N. Finck
J Biol Chem. 2022 Feb; 298(2): 101554. Published online 2021 Dec 30. doi: 10.1016/j.jbc.2021.101554
PMCID:
PMC8808181
AbstractArticlePDF–2.5M
5.
Nutritional Modulation of Heart Failure in Mitochondrial Pyruvate Carrier-Deficient Mice
Kyle S. McCommis, Attila Kovacs, Carla J. Weinheimer, Trevor M. Shew, Timothy R. Koves, Olga R. Ilkayeva, Dakota R. Kamm, Kelly D. Pyles, M. Todd King, Richard L. Veech, Brian J. DeBosch, Deborah M. Muoio, Richard W. Gross, Brian N. Finck
Nat Metab. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Nat Metab. 2020 Nov; 2(11): 1232–1247. Published online 2020 Oct 26. doi: 10.1038/s42255-020-00296-1
PMCID:
PMC7957960
AbstractArticlePDF–5.9M
6.
Loss of Mitochondrial Pyruvate Carrier 2 in Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling
Kyle S. McCommis, Zhouji Chen, Xiaorong Fu, William G. McDonald, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, Brian N. Finck
Cell Metab. Author manuscript; available in PMC 2016 Oct 6.
Published in final edited form as: Cell Metab. 2015 Oct 6; 22(4): 682–694. Published online 2015 Sep 3. doi: 10.1016/j.cmet.2015.07.028
PMCID:
PMC4598280
AbstractArticlePDF–3.8M
7.
The role of the mitochondrial pyruvate carrier in substrate regulation
Nathaniel M. Vacanti, Ajit S. Divakaruni, Courtney R. Green, Seth J. Parker, Robert R. Henry, Theodore P. Ciaraldi, Anne N. Murphy, Christian M. Metallo
Mol Cell. Author manuscript; available in PMC 2015 Nov 6.
Published in final edited form as: Mol Cell. 2014 Nov 6; 56(3): 425–435. Published online 2014 Oct 30. doi: 10.1016/j.molcel.2014.09.024
PMCID:
PMC4267523
AbstractArticlePDF–1.4M
8.
Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion
Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, Brian N. Finck
Cell Rep. Author manuscript; available in PMC 2014 Jul 15.
Published in final edited form as: Cell Rep. 2014 Jun 26; 7(6): 2042–2053. Published online 2014 Jun 5. doi: 10.1016/j.celrep.2014.05.017
PMCID:
PMC4074444
AbstractArticlePDF–1.3M
9.
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
Nicole K.H. Yiew, Stanislaw Deja, Daniel Ferguson, Kevin Cho, Chaowapong Jarasvaraparn, Miriam Jacome-Sosa, Andrew J. Lutkewitte, Sandip Mukherjee, Xiaorong Fu, Jason M. Singer, Gary J. Patti, Shawn C. Burgess, Brian N. Finck
iScience. 2023 Nov 17; 26(11): 108196. Published online 2023 Oct 12. doi: 10.1016/j.isci.2023.108196
PMCID:
PMC10628847
AbstractArticlePDF–4.6M
10.
Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult
Nicole K.H. Yiew, Joel H. Vazquez, Michael R. Martino, Stefanie Kennon-McGill, Jake R. Price, Felicia D. Allard, Eric U. Yee, Alexander J. Layman, Laura P. James, Kyle S. McCommis, Brian N. Finck, Mitchell R. McGill
Mol Metab. 2023 Nov; 77: 101808. Published online 2023 Sep 15. doi: 10.1016/j.molmet.2023.101808
PMCID:
PMC10561123
AbstractArticlePDF–2.6M
11.
Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: ROLE OF MITOCHONDRIAL PYRUVATE CARRIER 2 (MPC2) ACETYLATION
Shraddha S. Vadvalkar, Satoshi Matsuzaki, Craig A. Eyster, Jennifer R. Giorgione, Lee B. Bockus, Caroline S. Kinter, Michael Kinter, Kenneth M. Humphries
J Biol Chem. 2017 Mar 17; 292(11): 4423–4433. Published online 2017 Feb 1. doi: 10.1074/jbc.M116.753509
PMCID:
PMC5377762
AbstractArticlePDF–1.6M
12.
Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy
Mariana Fernandez-Caggiano, Alisa Kamynina, Asvi A. Francois, Oleksandra Prysyazhna, Thomas R. Eykyn, Susanne Krasemann, Maria G. Crespo-Leiro, Maria Garcia Vieites, Katiuscia Bianchi, Valle Morales, Nieves Domenech, Philip Eaton
Nat Metab. Author manuscript; available in PMC 2021 Mar 23.
Published in final edited form as: Nat Metab. 2020 Nov 1; 2(11): 1223–1231. Published online 2020 Oct 26. doi: 10.1038/s42255-020-00276-5
PMCID:
PMC7610404
AbstractArticlePDF–3.5M
13.
Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet
Benoît Vanderperre, Sébastien Herzig, Petra Krznar, Manuel Hörl, Zeinab Ammar, Sylvie Montessuit, Sandra Pierredon, Nicola Zamboni, Jean-Claude Martinou
PLoS Genet. 2016 May; 12(5): e1006056. Published online 2016 May 13. doi: 10.1371/journal.pgen.1006056
PMCID:
PMC4866774
AbstractArticlePDF–1.6M
14.
A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans
Daniel K. Bricker, Eric B. Taylor, John C. Schell, Thomas Orsak, Audrey Boutron, Yu-Chan Chen, James E. Cox, Caleb M. Cardon, Jonathan G. Van Vranken, Noah Dephoure, Claire Redin, Sihem Boudina, Steven P. Gygi, Michèle Brivet, Carl S. Thummel, Jared Rutter
Science. Author manuscript; available in PMC 2013 Jun 24.
Published in final edited form as: Science. 2012 Jul 6; 337(6090): 96–100. Published online 2012 May 24. doi: 10.1126/science.1218099
PMCID:
PMC3690818
AbstractArticlePDF–2.1M
15.
RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation
Hong‐Bin Liu, Tahir Muhammad, Yueshuai Guo, Meng‐Jing Li, Qian‐Qian Sha, Chuan‐Xin Zhang, Hui Liu, Shi‐Gang Zhao, Han Zhao, Hao Zhang, Yan‐Zhi Du, Kang Sun, Kui Liu, Gang Lu, Xue‐Jiang Guo, Jiahao Sha, Heng‐Yu Fan, Fei Gao, Zi‐Jiang Chen
Adv Sci (Weinh) 2019 Aug 7; 6(15): 1900295. Published online 2019 May 24. doi: 10.1002/advs.201900295
PMCID:
PMC6685478
AbstractArticlePDF–3.0M
16.
Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
Sandip K. Bose, Irina Hutson, Charles A. Harris
Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615
PMCID:
PMC5133352
AbstractArticle
17.
Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase
Edward R. Strong, John C. Schimenti
Genes (Basel) 2010 Dec; 1(3): 440–451. Published online 2010 Dec 2. doi: 10.3390/genes1030440
PMCID:
PMC3139512
AbstractArticlePDF–473K
18.
Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue
Delphine Duteil, Milica Tosic, Franziska Lausecker, Hatice Z. Nenseth, Judith M. Müller, Sylvia Urban, Dominica Willmann, Kerstin Petroll, Nadia Messaddeq, Laura Arrigoni, Thomas Manke, Jan-Wilhelm Kornfeld, Jens C. Brüning, Vyacheslav Zagoriy, Michael Meret, Jörn Dengjel, Toufike Kanouni, Roland Schüle
Cell Rep. 2016 Oct 18; 17(4): 1008–1021. Published online 2016 Oct 18. doi: 10.1016/j.celrep.2016.09.053
PMCID:
PMC5081406
AbstractArticle
19.
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series
Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang
Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16
PMCID:
PMC4946427
AbstractArticlePDF–3.4M
20.
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome
Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin
PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994
PMCID:
PMC4605610
AbstractArticlePDF–6.8M

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