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Select item 81769041.

Tensin 1 (TNS1) is a modifier gene for low body mass index (BMI) in homozygous [F508del]CFTR patients

Nathan I. Walton, Xijun Zhang, Anthony R. Soltis, Joshua Starr, Clifton L. Dalgard, Matthew D. Wilkerson, Douglas Conrad, Harvey B. Pollard

Physiol Rep. 2021 Jun; 9(11): e14886. Published online 2021 Jun 4. doi: 10.14814/phy2.14886

PMCID:: PMC8176904

Abstract Article PDF–1.3M

Select item 77559192.

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

Kung-Chi Chang, Sarah D. Diermeier, Allen T. Yu, Lily D. Brine, Suzanne Russo, Sonam Bhatia, Habeeb Alsudani, Karen Kostroff, Tawfiqul Bhuiya, Edi Brogi, Darryl J. Pappin, C. Frank Bennett, Frank Rigo, David L. Spector

Nat Commun. 2020; 11: 6438. Published online 2020 Dec 22. doi: 10.1038/s41467-020-20207-y

PMCID:: PMC7755919

Abstract Article PDF–2.7M

Select item 69086813.

Tensin1 expression and function in chronic obstructive pulmonary disease

Panayiota Stylianou, Katherine Clark, Bibek Gooptu, Dawn Smallwood, Christopher E. Brightling, Yassine Amrani, Katy M. Roach, Peter Bradding

Sci Rep. 2019; 9: 18942. Published online 2019 Dec 12. doi: 10.1038/s41598-019-55405-2

PMCID:: PMC6908681

Abstract Article PDF–1.9M

Select item 68612244.

Hyperactivity of Mek in TNS1 knockouts leads to potential treatments for cystic kidney diseases

Zong-Ye Wu, Chun-Lung Chiu, Ethan Lo, Yuh-Ru Julie Lee, Soichiro Yamada, Su Hao Lo

Cell Death Dis. 2019 Dec; 10(12): 871. Published online 2019 Nov 18. doi: 10.1038/s41419-019-2119-7

PMCID:: PMC6861224

Abstract Article PDF–3.2M

Select item 54495085.

Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation

Ksenija Bernau, Elizabeth E. Torr, Michael D. Evans, Jason K. Aoki, Caitlyn R. Ngam, Nathan Sandbo

Am J Respir Cell Mol Biol. 2017 Apr; 56(4): 465–476. doi: 10.1165/rcmb.2016-0104OC

PMCID:: PMC5449508

Abstract Article PDF–2.0M

Select item 93674406.

Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells

Gi Cheol Park, Ji Min Kim, Sung-Chan Shin, Yong-il Cheon, Eui-Suk Sung, Minhyung Lee, Jin-Choon Lee, Byung-Joo Lee

Cells. 2022 Aug; 11(15): 2333. Published online 2022 Jul 29. doi: 10.3390/cells11152333

PMCID:: PMC9367440

Abstract Article PDF–4.5M

Select item 77850407.

miR-152/TNS1 axis inhibits non-small cell lung cancer progression through Akt/mTOR/RhoA pathway

Jinjin Duan, Li Wang, Liqun Shang, Shumei Yang, Hua Wu, Yongcheng Huang, Yi Miao

Biosci Rep. 2021 Jan 29; 41(1): BSR20201539. Published online 2021 Jan 4. doi: 10.1042/BSR20201539

PMCID:: PMC7785040

Abstract Article PDF–1.0M

Select item 58760838.

Hic-5 Regulates Fibrillar Adhesion Formation to Control Tumor Extracellular Matrix Remodeling through Interaction with Tensin1

Gregory J. Goreczny, Ian J. Forsythe, Christopher E. Turner

Oncogene. Author manuscript; available in PMC 2018 Jul 19.

Published in final edited form as: Oncogene. 2018 Mar; 37(13): 1699–1713. Published online 2018 Jan 19. doi: 10.1038/s41388-017-0074-2

PMCID:: PMC5876083

Abstract Article PDF–3.8M

Select item 54231749.

MicroRNA‐548j functions as a metastasis promoter in human breast cancer by targeting Tensin1

Yun Zhan, Xiaoshuan Liang, Lin Li, Baona Wang, Fang Ding, Yi Li, Xiang Wang, Qimin Zhan, Zhihua Liu

Mol Oncol. 2016 Jun; 10(6): 838–849. Published online 2016 Feb 23. doi: 10.1016/j.molonc.2016.02.002

PMCID:: PMC5423174

Abstract Article PDF–3.7M

Select item 310186510.

Comprehensive Analysis of Phosphorylation Sites in Tensin1 Reveals Regulation by p38MAPK

Emily H. Hall, Jeremy L. Balsbaugh, Kristie L. Rose, Jeffrey Shabanowitz, Donald F. Hunt, David L. Brautigan

Mol Cell Proteomics. 2010 Dec; 9(12): 2853–2863. Published online 2010 Aug 26. doi: 10.1074/mcp.M110.003665

PMCID:: PMC3101865

Abstract Article PDF–1.1M

Select item 780349611.

LncRNA MAGI2-AS3 inhibits bladder cancer progression by targeting the miR-31-5p/TNS1 axis

Congyi Tang, Yi Cai, Huichuan Jiang, Zhengtong Lv, Changzhao Yang, Haozhe Xu, Zhi Li, Yuan Li

Aging (Albany NY) 2020 Dec 31; 12(24): 25547–25563. Published online 2020 Nov 20. doi: 10.18632/aging.104162

PMCID:: PMC7803496

Abstract Article PDF–1.6M

Select item 278733412.

Tensin1 Requires Protein Phosphatase-1α in Addition to RhoGAP DLC-1 to Control Cell Polarization, Migration, and Invasion

Emily H. Hall, Abbi E. Daugherty, Colin K. Choi, Alan F. Horwitz, David L. Brautigan

J Biol Chem. 2009 Dec 11; 284(50): 34713–34722. Published online 2009 Oct 13. doi: 10.1074/jbc.M109.059592

PMCID:: PMC2787334

Abstract Article PDF–2.2M

Select item 980157313.

lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m⁶A reader YTHDC2

Jin Wang, Lirong Tan, Xueting Yu, Xiyuan Cao, Beibei Jia, Rui Chen, Jianxiang Li

Mol Cancer. 2022; 21: 229. Published online 2022 Dec 30. doi: 10.1186/s12943-022-01705-7

PMCID:: PMC9801573

Abstract Article PDF–17M

Select item 263288614.

Tensin3 Is a Negative Regulator of Cell Migration and All Four Tensin Family Members Are Downregulated in Human Kidney Cancer

Danuta Martuszewska, Börje Ljungberg, Martin Johansson, Göran Landberg, Cecilia Oslakovic, Björn Dahlbäck, Sassan Hafizi

PLoS One. 2009; 4(2): e4350. Published online 2009 Feb 4. doi: 10.1371/journal.pone.0004350

PMCID:: PMC2632886

Abstract Article PDF–1.2M

Select item 339841615.

Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function

María Soler Artigas, Louise V. Wain, Emmanouela Repapi, Ma'en Obeidat, Ian Sayers, Paul R. Burton, Toby Johnson, Jing Hua Zhao, Eva Albrecht, Anna F. Dominiczak, Shona M. Kerr, Blair H. Smith, Gemma Cadby, Jennie Hui, Lyle J. Palmer, Aroon D. Hingorani, S. Goya Wannamethee, Peter H. Whincup, Shah Ebrahim, George Davey Smith, Inês Barroso, Ruth J. F. Loos, Nicholas J. Wareham, Cyrus Cooper, Elaine Dennison, Seif O. Shaheen, Jason Z. Liu, Jonathan Marchini, Santosh Dahgam, Åsa Torinsson Naluai, Anna-Carin Olin, Stefan Karrasch, Joachim Heinrich, Holger Schulz, Tricia M. McKeever, Ian D. Pavord, Markku Heliövaara, Samuli Ripatti, Ida Surakka, John D. Blakey, Mika Kähönen, John R. Britton, Fredrik Nyberg, John W. Holloway, Debbie A. Lawlor, Richard W. Morris, Alan L. James, Cathy M. Jackson, Ian P. Hall, Martin D. Tobin, Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, the SpiroMeta Consortium

Am J Respir Crit Care Med. 2011 Oct 1; 184(7): 786–795. Published online 2011 Oct 1. doi: 10.1164/rccm.201102-0192OC

PMCID:: PMC3398416

Abstract Article PDF–584K

Select item 122137616.

Molecular characterization of human tensin.

H Chen, A Ishii, W K Wong, L B Chen, S H Lo

Biochem J. 2000 Oct 15; 351(Pt 2): 403–411.

PMCID:: PMC1221376

Summary PDF–427K

Select item 5553017.

Nephrocystin interacts with Pyk2, p130^Cas, and tensin and triggers phosphorylation of Pyk2

Thomas Benzing, Peter Gerke, Katja Höpker, Friedhelm Hildebrandt, Emily Kim, Gerd Walz

Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17): 9784–9789. Published online 2001 Aug 7. doi: 10.1073/pnas.171269898

PMCID:: PMC55530

Abstract Article PDF–462K

Select item 206362318.

The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1

Yi-Chun Liao, Lizhen Si, Ralph W. deVere White, Su Hao Lo

J Cell Biol. 2007 Jan 1; 176(1): 43–49. doi: 10.1083/jcb.200608015

PMCID:: PMC2063623

Abstract Article PDF–1.4M

Select item 286296519.

Genome-wide association study identifies five loci associated with lung function

Emmanouela Repapi, Ian Sayers, Louise V Wain, Paul R Burton, Toby Johnson, Ma’en Obeidat, Jing Hua Zhao, Adaikalavan Ramasamy, Guangju Zhai, Veronique Vitart, Jennifer E Huffman, Wilmar Igl, Eva Albrecht, Panos Deloukas, John Henderson, Raquel Granell, Wendy L McArdle, Alicja R Rudnicka, Wellcome Trust Case Control Consortium, Inês Barroso, Ruth J F Loos, Nicholas J Wareham, Linda Mustelin, Taina Rantanen, Ida Surakka, Medea Imboden, H Erich Wichmann, Ivica Grkovic, Stipan Jankovic, Lina Zgaga, Anna-Liisa Hartikainen, Leena Peltonen, Ulf Gyllensten, Åsa Johansson, Ghazal Zaboli, Harry Campbell, Sarah H Wild, James F Wilson, Sven Gläser, Georg Homuth, Henry Völzke, Massimo Mangino, Nicole Soranzo, Tim D Spector, Ozren Polašek, Igor Rudan, Alan F Wright, Markku Heliövaara, Samuli Ripatti, Anneli Pouta, Åsa Torinsson Naluai, Anna-Carin Olin, Kjell Torén, Matthew N Cooper, Alan L James, Lyle J Palmer, Aroon D Hingorani, S Goya Wannamethee, Peter H Whincup, George Davey Smith, Shah Ebrahim, Tricia M McKeever, Ian D Pavord, Andrew K MacLeod, Andrew D Morris, David J Porteous, Cyrus Cooper, Elaine Dennison, Seif Shaheen, Stefan Karrasch, Eva Schnabel, Holger Schulz, Harald Grallert, Nabila Bouatia-Naji, Jérôme Delplanque, Philippe Froguel, John D Blakey, The NSHD Respiratory Study Team, John R Britton, Richard W Morris, John W Holloway, Debbie A Lawlor, Jennie Hui, Fredrik Nyberg, Marjo-Riitta Jarvelin, Cathy Jackson, Mika Kähönen, Jaakko Kaprio, Nicole M Probst-Hensch, Beate Koch, Caroline Hayward, David M Evans, Paul Elliott, David P Strachan, Ian P Hall, Martin D Tobin

Nat Genet. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Nat Genet. 2010 Jan; 42(1): 36–44. Published online 2009 Dec 13. doi: 10.1038/ng.501

PMCID:: PMC2862965

Abstract Article PDF–1.0M

Select item 428018320.

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

Manuel A. R. Ferreira, Melanie C. Matheson, Clara S. Tang, Raquel Granell, Wei Ang, Jennie Hui, Amy K. Kiefer, David L. Duffy, Svetlana Baltic, Patrick Danoy, Minh Bui, Loren Price, Peter D. Sly, Nicholas Eriksson, Pamela A. Madden, Michael J. Abramson, Patrick G. Holt, Andrew C. Heath, Michael Hunter, Bill Musk, Colin F. Robertson, Peter Le Souëf, Grant W. Montgomery, A. John Henderson, Joyce Y. Tung, Shyamali C. Dharmage, Matthew A. Brown, Alan James, Philip J. Thompson, Craig Pennell, Nicholas G. Martin, David M. Evans, David A. Hinds, John L. Hopper, the Australian Asthma Genetics Consortium Collaborators

J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2014 Jun; 133(6): 1564–1571. Published online 2013 Dec 31. doi: 10.1016/j.jaci.2013.10.030

PMCID:: PMC4280183

Abstract Article PDF–350K

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