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Select item 112398941.

Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts

Himanshi Agarwal, Perry Tal, Naomi Goldfinger, Esita Chattopadhyay, David Malkin, Varda Rotter, Ayush Attery

Cell Death Differ. 2024 Jul; 31(7): 855–867. Published online 2024 May 14. doi: 10.1038/s41418-024-01307-4

PMCID:: PMC11239894

Abstract Article PDF–4.1M

Select item 112309572.

p53 protein expression patterns associated with TP53 mutations in breast carcinoma

Sarah A. Anderson, Brooke B. Bartow, Shuko Harada, Gene P. Siegal, Shi Wei, Valeria L. Dal Zotto, Xiao Huang

Breast Cancer Res Treat. 2024; 207(1): 213–222. Published online 2024 Jun 20. doi: 10.1007/s10549-024-07357-z

PMCID:: PMC11230957

Abstract Article PDF–1.5M

Select item 111591173.

Etiologic value of p53 mutation spectra and differences with histology in lung cancers

Takuo Shimmyo, Akira Okada, Takehisa Hashimoto, Yasuhito Kobayashi, Youhei Miyagi, Yuichi Ishikawa, Ken Nakagawa, Hiroaki Osada, Eiju Tsuchiya

Cancer Sci. 2008 Feb; 99(2): 287–295. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2007.00686.x

PMCID:: PMC11159117

Abstract Article PDF–169K

Select item 111590864.

p53 Gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: Results in Japan and comparisons with other countries

Akinori Egashira, Masaru Morita, Yoshihiro Kakeji, Noriaki Sadanaga, Eiji Oki, Takuya Honbo, Mitsuhiko Ohta, Yoshihiko Maehara

Cancer Sci. 2007 Aug; 98(8): 1152–1156. Published online 2007 Jun 15. doi: 10.1111/j.1349-7006.2007.00524.x

PMCID:: PMC11159086

Abstract Article PDF–110K

Select item 111588695.

Risk of p53 gene mutation in esophageal squamous cell carcinoma and habit of betel quid chewing in Taiwanese

Yih‐Gang Goan, Huang‐Chou Chang, Hon‐Ki Hsu, Yi‐Pin Chou, Jiin‐Tsuey Cheng

Cancer Sci. 2005 Nov; 96(11): 758–765. Published online 2005 Nov 4. doi: 10.1111/j.1349-7006.2005.00115.x

PMCID:: PMC11158869

Abstract Article PDF–110K

Select item 111582426.

Identification of p53–46F as a super p53 with an enhanced ability to induce p53‐dependent apoptosis

Yasuyuki Nakamura, Manabu Futamura, Hiroki Kamino, Koji Yoshida, Yusuke Nakamura, Hirofumi Arakawa

Cancer Sci. 2006 Jul; 97(7): 633–641. Published online 2006 May 15. doi: 10.1111/j.1349-7006.2006.00214.x

PMCID:: PMC11158242

Abstract Article PDF–398K

Select item 111468487.

Covalent and noncovalent modifiers of the p53 protein

L. Jayaraman, C. Prives

Cell Mol Life Sci. 1999 Jan; 55(1): 76–87. Published online 2014 Feb 6. doi: 10.1007/s000180050271

PMCID:: PMC11146848

Abstract PDF–239K

Select item 111316928.

Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation

T. Chen, Y. S. Wong

Cell Mol Life Sci. 2008 Sep; 65(17): 2763. Published online 2008 Jul 26. doi: 10.1007/s00018-008-8329-2

PMCID:: PMC11131692

Abstract Article PDF–1.4M

Select item 111212369.

Comprehensive Bioinformatic Investigation of TP53 Dysregulation in Diverse Cancer Landscapes

Ruby Khan, Bakht Pari, Krzysztof Puszynski

Genes (Basel) 2024 May; 15(5): 577. Published online 2024 Apr 30. doi: 10.3390/genes15050577

PMCID:: PMC11121236

Abstract Article PDF–6.0M

Select item 1107212910.

Oncogenic pathways activated by pro-inflammatory cytokines promote mutant p53 stability: clue for novel anticancer therapies

Gabriella D’Orazi, Marco Cordani, Mara Cirone

Cell Mol Life Sci. 2021 Mar; 78(5): 1853–1860. Published online 2020 Oct 17. doi: 10.1007/s00018-020-03677-7

PMCID:: PMC11072129

Abstract Article PDF–863K

Select item 1103744911.

TP53 Null Mutations Identify Lung Cancer Cell Lines with Highest Sensitivity to the Nontaxane Microtubule Inhibitor Eribulin

Trista K. Hinz, Roshni Kalkur, Jonathan Rabinovitch, Wyatt Hinkle, Lynn E. Heasley

Mol Pharmacol. 2021 Aug; 100(2): 144–154. Published online 2021 Aug. doi: 10.1124/molpharm.121.000254

PMCID:: PMC11037449

Abstract Article PDF–2.1M

Select item 1102855812.

Induction of tumor-reactive T helper responses by a posttranslational modified epitope from tumor protein p53

Takumi Kumai, Kei Ishibashi, Kensuke Oikawa, Yoshinari Matsuda, Naoko Aoki, Shoji Kimura, Satoshi Hayashi, Masahiro Kitada, Yasuaki Harabuchi, Esteban Celis, Hiroya Kobayashi

Cancer Immunol Immunother. 2014 May; 63(5): 469–478. Published online 2014 Mar 15. doi: 10.1007/s00262-014-1533-z

PMCID:: PMC11028558

Abstract Article PDF–768K

Select item 1098545013.

Susceptibility of pediatric acute lymphoblastic leukemia to STAT3 inhibition depends on p53 induction

Luca Gasparoli, Clemence Virely, Alexia Tsakaneli, Noelia Che, Darren Edwards, Jack Bartram, Michael Hubank, Deepali Pal, Olaf Heidenreich, Joost H.A. Martens, Jasper de Boer, Owen Williams

Haematologica. 2024 Apr 1; 109(4): 1069–1081. Published online 2023 Oct 5. doi: 10.3324/haematol.2023.283613

PMCID:: PMC10985450

Abstract Article PDF–3.0M

Select item 1093745114.

Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors

Monika Pękul, Magdalena Szczepaniak, Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Szymon Baluszek, Artur Kowalik, Maria Maksymowicz, Grzegorz Zieliński, Jacek Kunicki, Przemysław Witek, Mateusz Bujko

Front Endocrinol (Lausanne) 2024; 15: 1302667. Published online 2024 Feb 29. doi: 10.3389/fendo.2024.1302667

PMCID:: PMC10937451

Abstract Article PDF–20M

Select item 1090567715.

Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne

K. Kast, K. Rhiem, M. Larsen, B. Wappenschmidt, R. Schmutzler

Cancer Med. 2024 Feb; 13(3): e6920. Published online 2024 Jan 17. doi: 10.1002/cam4.6920

PMCID:: PMC10905677

Abstract Article PDF–349K

Select item 1085110316.

Multi-endpoint analysis of cadmium chloride-induced genotoxicity shows role for reactive oxygen species and p53 activation in DNA damage induction, cell cycle irregularities, and cell size aberrations

Leanne M Stannard, Ann Doherty, Katherine E Chapman, Shareen H Doak, Gareth J Jenkins

Mutagenesis. 2024 Jan; 39(1): 13–23. Published online 2023 Aug 9. doi: 10.1093/mutage/gead025

PMCID:: PMC10851103

Abstract Article PDF–802K

Select item 1082326717.

Impact of TP53‐induced glycolysis and apoptosis regulator on malignant activity and resistance to ferroptosis in intrahepatic cholangiocarcinoma

Katsuya Toshida, Shinji Itoh, Norifumi Iseda, Takuma Izumi, Shohei Yoshiya, Takeo Toshima, Mizuki Ninomiya, Takeshi Iwasaki, Yoshinao Oda, Tomoharu Yoshizumi

Cancer Sci. 2024 Jan; 115(1): 170–183. Published online 2023 Oct 25. doi: 10.1111/cas.15981

PMCID:: PMC10823267

Abstract Article PDF–6.9M

Select item 1081529018.

Clinical and functional analysis of the germline TP53 p.K164E acetylation site variant

Emilia Modolo Pinto, Enilze M.S.F. Ribeiro, Jinling Wang, Aaron H. Phillips, Richard W. Kriwacki, Gerard P. Zambetti

Cold Spring Harb Mol Case Stud. 2023 Dec; 9(4): a006290. doi: 10.1101/mcs.a006290

PMCID:: PMC10815290

Abstract Article PDF–6.6M

Select item 1080035619.

Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease

Mary T. Scott, Wei Liu, Rebecca Mitchell, Cassie J. Clarke, Ross Kinstrie, Felix Warren, Hassan Almasoudi, Thomas Stevens, Karen Dunn, John Pritchard, Mark E. Drotar, Alison M. Michie, Heather G. Jørgensen, Brian Higgins, Mhairi Copland, David Vetrie

Nat Commun. 2024; 15: 651. Published online 2024 Jan 22. doi: 10.1038/s41467-024-44771-9

PMCID:: PMC10800356

Abstract Article PDF–7.3M

Select item 1076601820.

Low‐burden TP53 mutations represent frequent genetic events in CLL with an increased risk for treatment initiation

Tamás László, Lili Kotmayer, Viktória Fésüs, Lajos Hegyi, Stefánia Gróf, Ákos Nagy, Béla Kajtár, Alexandra Balogh, Júlia Weisinger, Tamás Masszi, Zsolt Nagy, Péter Farkas, Judit Demeter, Ildikó Istenes, Róbert Szász, Lajos Gergely, Adrienn Sulák, Zita Borbényi, Dóra Lévai, Tamás Schneider, Piroska Pettendi, Emese Bodai, László Szerafin, László Rejtő, Árpád Bátai, Mária Á Dömötör, Hermina Sánta, Márk Plander, Tamás Szendrei, Aryan Hamed, Zsolt Lázár, Zsolt Pauker, Gáspár Radványi, Adrienn Kiss, Gábor Körösmezey, János Jakucs, Péter J Dombi, Zsófia Simon, Zsolt Klucsik, Mihály Gurzó, Márta Tiboly, Tímea Vidra, Péter Ilonczai, András Bors, Hajnalka Andrikovics, Miklós Egyed, Tamás Székely, András Masszi, Donát Alpár, András Matolcsy, Csaba Bödör

J Pathol Clin Res. 2024 Jan; 10(1): e351. Published online 2023 Nov 21. doi: 10.1002/cjp2.351

PMCID:: PMC10766018

Abstract Article PDF–1.5M

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