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Select item 108543701.

HylS’, a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by interaction with host complement factor C3b

Jiajia Xu, Long Chen, Siqi Pang, Qiuhong Zhang, Simin Deng, Jiaqi Zhu, Xiabing Chen, Paul R Langford, Qi Huang, Rui Zhou, Lu Li

Virulence. 2024; 15(1): 2306691. Published online 2024 Jan 22. doi: 10.1080/21505594.2024.2306691

PMCID:: PMC10854370

Abstract Article PDF–10M

Select item 108156962.

Serum Uric Acid Associates with Systemic Complement C3 Activation in Severe ANCA-Associated Renal Vasculitides

Eva Baier, Ingmar Alexander Kluge, Samy Hakroush, Peter Korsten, Björn Tampe

Int J Mol Sci. 2024 Jan; 25(2): 713. Published online 2024 Jan 5. doi: 10.3390/ijms25020713

PMCID:: PMC10815696

Abstract Article PDF–1.3M

Select item 107675743.

Defective C3d caused by C3 p.W1034R in inherited atypical hemolytic uremic syndrome

Masafumi Tsuchida, Shin Goto, Hirofumi Watanabe, Sawako Goto, Hiroki Yamaguchi, Ichiei Narita

Mol Genet Genomic Med. 2024 Jan; 12(1): e2288. Published online 2023 Oct 5. doi: 10.1002/mgg3.2288

PMCID:: PMC10767574

Abstract Article PDF–1.0M

Select item 102304094.

Complement protein C3a enhances adaptive immune responses towards FVIII products

Eva Ringler, Samira Ortega Iannazzo, Jessica Herzig, Lisa M. Weiss, Martina Anzaghe, Lilija Miller, Zoe Waibler

Haematologica. 2023 Jun 1; 108(6): 1579–1589. Published online 2023 Feb 2. doi: 10.3324/haematol.2022.281762

PMCID:: PMC10230409

Abstract Article PDF–2.9M

Select item 98076175.

Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis

Yuqiang Pei, Jing Zhang, Jingge Qu, Yafei Rao, Danyang Li, Xiaoyan Gai, Yahong Chen, Ying Liang, Yongchang Sun

Front Immunol. 2022; 13: 1035930. Published online 2022 Dec 20. doi: 10.3389/fimmu.2022.1035930

PMCID:: PMC9807617

Abstract Article PDF–7.6M

Select item 96921286.

Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity

Eva Baier, Désirée Tampe, Ingmar Alexander Kluge, Samy Hakroush, Björn Tampe

Front Immunol. 2022; 13: 1054457. Published online 2022 Nov 11. doi: 10.3389/fimmu.2022.1054457

PMCID:: PMC9692128

Abstract Article PDF–3.6M

Select item 91633917.

Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis

Rajia Bahri, Orsolya Kiss, Ian Prise, Karen M. Garcia-Rodriguez, Haris Atmoko, Julia M. Martínez-Gómez, Mitchell P. Levesque, Reinhard Dummer, Michael P. Smith, Claudia Wellbrock, Silvia Bulfone-Paus

Front Immunol. 2022; 13: 861545. Published online 2022 May 20. doi: 10.3389/fimmu.2022.861545

PMCID:: PMC9163391

Abstract Article PDF–12M

Select item 90704118.

Maternal C3 complement and C-reactive protein and pregnancy and fetal outcomes: A secondary analysis of the PEARS RCT-An mHealth-supported, lifestyle intervention among pregnant women with overweight and obesity

Maria A. Kennelly, Sarah Louise Killeen, Catherine M. Phillips, Gouiri Alberdi, Karen L. Lindsay, John Mehegan, Martina Cronin, Fionnuala M. McAuliffe

Cytokine. Author manuscript; available in PMC 2022 May 5.

Published in final edited form as: Cytokine. 2022 Jan; 149: 155748. Published online 2021 Oct 23. doi: 10.1016/j.cyto.2021.155748

PMCID:: PMC9070411

Abstract Article PDF–632K

Select item 90394909.

Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia

Evans Raballah, Samuel B Anyona, Qiuying Cheng, Elly O Munde, Ivy-Foo Hurwitz, Clinton Onyango, Caroline Ndege, Nicolas W Hengartner, Maria Andreína Pacheco, Ananias A Escalante, Christophe G Lambert, Collins Ouma, Henri C Jr T Obama, Kristan A Schneider, Philip D Seidenberg, Benjamin H McMahon, Douglas J Perkins

Exp Biol Med (Maywood) 2022 Apr; 247(8): 672–682. Published online 2021 Nov 29. doi: 10.1177/15353702211056272

PMCID:: PMC9039490

Abstract Article PDF–1.2M

Select item 879184210.

Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients

Gustaf L. Isaksson, Marie B. Nielsen, Gitte R. Hinrichs, Nicoline V. Krogstrup, Rikke Zachar, Heidi Stubmark, Per Svenningsen, Kirsten Madsen, Claus Bistrup, Bente Jespersen, The CONTEXT Study Group, Henrik Birn, Yaseelan Palarasah, Boye L. Jensen

Am J Physiol Renal Physiol. 2022 Feb 1; 322(2): F150–F163. Published online 2021 Dec 20. doi: 10.1152/ajprenal.00300.2021

PMCID:: PMC8791842

Abstract Article

Select item 878353811.

Sub-setting systemic lupus erythematosus by combined molecular phenotypes defines divergent populations in two phase III randomized trials

Michelle Petri, Steven D Watts, Richard E Higgs, Matthew D Linnik

Rheumatology (Oxford) 2021 Nov; 60(11): 5390–5396. Published online 2021 Feb 12. doi: 10.1093/rheumatology/keab144

PMCID:: PMC8783538

Abstract Article PDF–162K

Select item 855727212.

Association between complement C3 and the prevalence of metabolic-associated fatty liver disease in a Chinese population: a cross-sectional study

Limin Feng, Ying Zhao, Wei-Lin Wang

BMJ Open. 2021; 11(10): e051218. Published online 2021 Oct 27. doi: 10.1136/bmjopen-2021-051218

PMCID:: PMC8557272

Abstract Article PDF–321K

Select item 834896813.

AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout

Blanca Chinchilla, Rosario Fernandez-Godino

Int J Mol Sci. 2021 Aug; 22(15): 8183. Published online 2021 Jul 30. doi: 10.3390/ijms22158183

PMCID:: PMC8348968

Abstract Article PDF–4.4M

Select item 823484114.

Complement Components C3 and C4 Indicate Vasculitis Manifestations to Distinct Renal Compartments in ANCA-Associated Glomerulonephritis

Samy Hakroush, Désirée Tampe, Peter Korsten, Philipp Ströbel, Björn Tampe

Int J Mol Sci. 2021 Jun; 22(12): 6588. Published online 2021 Jun 19. doi: 10.3390/ijms22126588

PMCID:: PMC8234841

Abstract Article PDF–1.8M

Select item 757487215.

Complement 3 mediates periodontal destruction in patients with type 2 diabetes by regulating macrophage polarization in periodontal tissues

Ye Li, Xinxin Wang, Saisai Wang, Chunhui Zhu, Jing Guo, Ke Li, Ang Li

Cell Prolif. 2020 Oct; 53(10): e12886. Published online 2020 Aug 14. doi: 10.1111/cpr.12886

PMCID:: PMC7574872

Abstract Article PDF–1.8M

Select item 744076216.

Differential Interactions of Serum and Bronchoalveolar Lavage Fluid Complement Proteins with Conidia of Airborne Fungal Pathogen Aspergillus fumigatus

Sarah Sze Wah Wong, Irene Daniel, Jean-Pierre Gangneux, Jeya Maheshwari Jayapal, Hélène Guegan, Sarah Dellière, Prajna Lalitha, Rajashri Shende, Taruna Madan, Jagadeesh Bayry, J. Iñaki Guijarro, Dharmalingam Kuppamuthu, Vishukumar Aimanianda

Infect Immun. 2020 Sep; 88(9): e00212-20. Prepublished online 2020 Jun 22. Published online 2020 Aug 19. doi: 10.1128/IAI.00212-20