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Select item 108766541.

VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma

Natalia Fernández-Parejo, L. Francisco Lorenzo-Martín, Juana M. García-Pedrero, Juan P. Rodrigo, Mercedes Dosil, Xosé R. Bustelo

Sci Rep. 2024; 14: 4060. Published online 2024 Feb 19. doi: 10.1038/s41598-024-54808-0

PMCID:: PMC10876654

Abstract Article PDF–17M

Select item 96815502.

The tRNA-Cys-GCA Derived tsRNAs Suppress Tumor Progression of Gliomas via Regulating VAV2

Jian Ren, Xiaoling Wu, Fei-Fei Shang, Yingqiang Qi, Zhurong Tang, Chunjie Wen, Weiguo Cao, Quan Cheng, Lihong Tan, Huan Chen, Hong-Hao Zhou, Hecun Zou

Dis Markers. 2022; 2022: 8708312. Published online 2022 Nov 15. doi: 10.1155/2022/8708312

PMCID:: PMC9681550

Abstract Article PDF–3.1M

Select item 84058163.

VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance

Weiling Liu, Chuanwang Miao, Shaosen Zhang, Yachen Liu, Xiangjie Niu, Yiyi Xi, Wenjia Guo, Jiahui Chu, Ai Lin, Hongjin Liu, Xinyu Yang, Xinjie Chen, Ce Zhong, Yuling Ma, Yuqian Wang, Shihao Zhu, Shuning Liu, Wen Tan, Dongxin Lin, Chen Wu

Signal Transduct Target Ther. 2021; 6: 322. Published online 2021 Aug 30. doi: 10.1038/s41392-021-00735-9

PMCID:: PMC8405816

Abstract Article PDF–5.9M

Select item 43626474.

Vav2 protein overexpression marks and may predict the aggressive subtype of ductal carcinoma in situ

YunQing Jiang, Indira Prabakaran, Fei Wan, Nandita Mitra, Dana K Furstenau, Rupert K Hung, Siyuan Cao, Paul J Zhang, Douglas L Fraker, Marina A Guvakova

Biomark Res. 2014; 2: 22. Published online 2014 Nov 28. doi: 10.1186/2050-7771-2-22

PMCID:: PMC4362647

Abstract Article PDF–1.2M

Select item 28628095.

Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivo

Myung-soon Moon, Timothy M. Gomez

Mol Cell Neurosci. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Mol Cell Neurosci. 2010 Jun; 44(2): 118–128. Published online 2010 Mar 16. doi: 10.1016/j.mcn.2010.03.001

PMCID:: PMC2862809

Abstract Article PDF–3.5M

Select item 862696.

Vav2 Activates Rac1, Cdc42, and RhoA Downstream from Growth Factor Receptors but Not β1 Integrins

Betty P. Liu, Keith Burridge

Mol Cell Biol. 2000 Oct; 20(19): 7160–7169. doi: 10.1128/mcb.20.19.7160-7169.2000

PMCID:: PMC86269

Abstract Article PDF–1.5M

Select item 65501277.

MicroRNA‐331‐3p inhibits epithelial‐mesenchymal transition by targeting ErbB2 and VAV2 through the Rac1/PAK1/β‐catenin axis in non‐small‐cell lung cancer

Xizhe Li, Jiali Zhu, Yuanqi Liu, Chaojun Duan, Ruimin Chang, Chunfang Zhang

Cancer Sci. 2019 Jun; 110(6): 1883–1896. Published online 2019 Apr 29. doi: 10.1111/cas.14014

PMCID:: PMC6550127

Abstract Article PDF–3.3M

Select item 60364188.

Ubiquitin E3 Ligase MARCH7 promotes proliferation and invasion of cervical cancer cells through VAV2-RAC1-CDC42 pathway

Jianguo Hu, Ying Meng, Jianhua Zeng, Biao Zeng, Xingwei Jiang

Oncol Lett. 2018 Aug; 16(2): 2312–2318. Published online 2018 Jun 5. doi: 10.3892/ol.2018.8908

PMCID:: PMC6036418

Abstract Article PDF–1.5M

Select item 54268499.

Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells

Brian J. Rosenberg, Hava Gil-Henn, Christopher C. Mader, Tiffany Halo, Taofei Yin, John Condeelis, Kazuya Machida, Yi I. Wu, Anthony J. Koleske

Mol Biol Cell. 2017 May 15; 28(10): 1347–1360. doi: 10.1091/mbc.E16-12-0885

PMCID:: PMC5426849

Abstract Article PDF–2.6M

Select item 529110310.

Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors

Nuria Perretta-Tejedor, Javier Fernández-Mateos, Luis García-Ortiz, Manuel A. Gómez-Marcos, José I. Recio-Rodríguez, Cristina Agudo-Conde, Emiliano Rodriguez-Sánchez, Ana I. Morales, Francisco J. López-Hernández, José M. López-Novoa, Rogelio González-Sarmiento, Carlos Martínez-Salgado

Sci Rep. 2017; 7: 41875. Published online 2017 Feb 3. doi: 10.1038/srep41875

Correction in:: Sci Rep. 2018; 8: 46977.

PMCID:: PMC5291103

Abstract Article PDF–438K

Select item 524764511.

EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer

Jing-Jing Li, Zhi-Jian Sun, Yan-Mei Yuan, Fen-Fen Yin, Yao-Gang Bian, Ling-Yun Long, Xue-li Zhang, Dong Xie

J Biol Chem. 2017 Jan 20; 292(3): 1112–1121. Published online 2016 Dec 16. doi: 10.1074/jbc.M116.750349

PMCID:: PMC5247645

Abstract Article PDF–3.0M

Select item 459120212.

VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells

Rajakrishnan Veluthakal, Ragadeepthi Tunduguru, Daleep Kumar Arora, Vaibhav Sidarala, Khadija Syeda, Cornelis P. Vlaar, Debbie C. Thurmond, Anjaneyulu Kowluru

Diabetologia. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Diabetologia. 2015 Nov; 58(11): 2573–2581. Published online 2015 Jul 31. doi: 10.1007/s00125-015-3707-4

PMCID:: PMC4591202

Abstract Article PDF–772K

Select item 368169413.

Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration

Matthew C. Jones, Kazuya Machida, Bruce J. Mayer, Christopher E. Turner

Mol Biol Cell. 2013 Jun 15; 24(12): 1882–1894. doi: 10.1091/mbc.E12-09-0654

PMCID:: PMC3681694

Abstract Article PDF–9.6M

Select item 366553214.

Potassium-Chloride Cotransporter 3 Interacts with Vav2 to Synchronize the Cell Volume Decrease Response with Cell Protrusion Dynamics

Adèle Salin-Cantegrel, Masoud Shekarabi, Sarah Rasheed, François M. Charron, Janet Laganière, Rebecca Gaudet, Patrick A. Dion, Jean-Yves Lapointe, Guy A. Rouleau

PLoS One. 2013; 8(5): e65294. Published online 2013 May 28. doi: 10.1371/journal.pone.0065294

PMCID:: PMC3665532

Abstract Article PDF–8.2M

Select item 30581715.

Vav-2 controls NFAT-dependent transcription inB- but not T-lymphocytes

Gina M. Doody, Daniel D. Billadeau, Elizabeth Clayton, Amanda Hutchings, Robert Berland, Simon McAdam, Paul J. Leibson, Martin Turner

EMBO J. 2000 Nov 15; 19(22): 6173–6184. doi: 10.1093/emboj/19.22.6173

PMCID:: PMC305817

Abstract Article PDF–641K

Select item 2663616.

Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

Akhilesh Pandey, Alexandre V. Podtelejnikov, Blagoy Blagoev, Xosé R. Bustelo, Matthias Mann, Harvey F. Lodish

Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1): 179–184. doi: 10.1073/pnas.97.1.179

PMCID:: PMC26636

Abstract Article PDF–167K

Select item 577027717.

Targeting AR Variant-coactivator Interactions to Exploit Prostate Cancer Vulnerabilities

Fiorella Magani, Stephanie O. Peacock, Meghan A. Rice, Maria J. Martinez, Ann M. Greene, Pablo S. Magani, Rolando Lyles, Jonathan R. Weitz, Kerry L. Burnstein

Mol Cancer Res. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Mol Cancer Res. 2017 Nov; 15(11): 1469–1480. Published online 2017 Aug 15. doi: 10.1158/1541-7786.MCR-17-0280

PMCID:: PMC5770277

Abstract Article PDF–577K

Select item 492473718.

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

Chien-Yu Cho, Kuo-Ting Lee, Wei-Ching Chen, Chih-Yang Wang, Yung-Sheng Chang, Hau-Lun Huang, Hui-Ping Hsu, Meng-Chi Yen, Ming-Zong Lai, Ming-Derg Lai

Oncotarget. 2016 Mar 22; 7(12): 14586–14604. Published online 2016 Feb 20. doi: 10.18632/oncotarget.7542

PMCID:: PMC4924737

Abstract Article PDF–6.0M

Select item 356185219.

Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin

Gabriela Valls, Montserrat Codina, Rachel K. Miller, Beatriz Del Valle-Pérez, Meritxell Vinyoles, Carme Caelles, Pierre D. McCrea, Antonio García de Herreros, Mireia Duñach

J Cell Sci. 2012 Nov 15; 125(22): 5288–5301. doi: 10.1242/jcs.101030