PMC Links for Gene (Select 75570) - PMC

Putzer J. Hung, Bo-Ruei Chen, Rosmy George, Caleb Liberman, Abigail J. Morales, Pedro Colon-Ortiz, Jessica K. Tyler, Barry P. Sleckman, Andrea L. Bredemeyer

Cell Cycle. 2017; 16(3): 286–295. Published online 2016 Nov 10. doi: 10.1080/15384101.2016.1253640

PMCID:: PMC5323033

Article PDF–1.0M

Select item 50358435.

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

Vipul Kumar, Frederick W. Alt, Richard L. Frock

Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38): 10619–10624. Published online 2016 Sep 6. doi: 10.1073/pnas.1611882113

PMCID:: PMC5035843

Article PDF–1.1M

Select item 49741996.

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination

Hanna IJspeert, Jacob Rozmus, Klaus Schwarz, René L. Warren, David van Zessen, Robert A. Holt, Ingrid Pico-Knijnenburg, Erik Simons, Isabel Jerchel, Angela Wawer, Myriam Lorenz, Turkan Patıroğlu, Himmet Haluk Akar, Ricardo Leite, Nicole S. Verkaik, Andrew P. Stubbs, Dik C. van Gent, Jacques J. M. van Dongen, Mirjam van der Burg

Blood. 2016 Aug 4; 128(5): 650–659. Prepublished online 2016 Jun 8. doi: 10.1182/blood-2016-02-701029

PMCID:: PMC4974199

Article

Select item 43366097.

Akt-mediated Phosphorylation of XLF Impairs Non-homologous End Joining DNA Repair

Pengda Liu, Wenjian Gan, Chunguang Guo, Anyong Xie, Daming Gao, Jianping Guo, Jinfang Zhang, Nicholas Willis, Arthur Su, John M. Asara, Ralph Scully, Wenyi Wei

Mol Cell. Author manuscript; available in PMC 2016 Feb 19.

Published in final edited form as: Mol Cell. 2015 Feb 19; 57(4): 648–661. Published online 2015 Feb 5. doi: 10.1016/j.molcel.2015.01.005

PMCID:: PMC4336609

Article PDF–1.8M

Select item 32893408.

Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair

Valentyn Oksenych, Frederick W. Alt, Vipul Kumar, Bjoern Schwer, Duane R. Wesemann, Erica Hansen, Harin Patel, Arthur Su, Chunguang Guo

Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7): 2455–2460. Published online 2012 Jan 30. doi: 10.1073/pnas.1121458109

PMCID:: PMC3289340

Article PDF–963K

Select item 18386339.

Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells

Shan Zha, Frederick W. Alt, Hwei-Ling Cheng, James W. Brush, Gang Li

Proc Natl Acad Sci U S A. 2007 Mar 13; 104(11): 4518–4523. Published online 2007 Mar 7. doi: 10.1073/pnas.0611734104

PMCID:: PMC1838633

Article PDF–562K

Select item 1028855410.

Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice

Yimeng Zhu, Wenxia Jiang, Brian J. Lee, Angelina Li, Steven Gershik, Shan Zha

Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2221894120. Published online 2023 Jun 12. doi: 10.1073/pnas.2221894120

PMCID:: PMC10288554

Article PDF–4.2M

Select item 660578611.

XLF and H2AX function in series to promote replication fork stability

Bo-Ruei Chen, Annabel Quinet, Andrea K. Byrum, Jessica Jackson, Matteo Berti, Saravanabhavan Thangavel, Andrea L. Bredemeyer, Issa Hindi, Nima Mosammaparast, Jessica K. Tyler, Alessandro Vindigni, Barry P. Sleckman

J Cell Biol. 2019 Jul 1; 218(7): 2113–2123. Published online 2019 May 23. doi: 10.1083/jcb.201808134

PMCID:: PMC6605786

Article PDF–2.2M

Select item 642675712.

Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice

Benoit Roch, Vincent Abramowski, Julie Chaumeil, Jean-Pierre de Villartay

Front Immunol. 2019; 10: 443. Published online 2019 Mar 14. doi: 10.3389/fimmu.2019.00443

PMCID:: PMC6426757

Article PDF–6.5M

Select item 521612813.

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice

Xiangyu Liu, Zhengping Shao, Wenxia Jiang, Brian J. Lee, Shan Zha

Nat Commun. 2017; 8: 13816. Published online 2017 Jan 4. doi: 10.1038/ncomms13816

PMCID:: PMC5216128

Article PDF–3.0M

Select item 415527114.

Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency

Serine Avagyan, Michael Churchill, Kenta Yamamoto, Jennifer L. Crowe, Chen Li, Brian J. Lee, Tian Zheng, Siddhartha Mukherjee, Shan Zha

Blood. 2014 Sep 4; 124(10): 1622–1625. Prepublished online 2014 Jul 29. doi: 10.1182/blood-2014-05-574863

PMCID:: PMC4155271

Article

Select item 263293315.

XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation

Enriqueta Riballo, Lisa Woodbine, Thomas Stiff, Sarah A. Walker, Aaron A. Goodarzi, Penny A. Jeggo

Nucleic Acids Res. 2009 Feb; 37(2): 482–492. Published online 2008 Dec 4. doi: 10.1093/nar/gkn957

PMCID:: PMC2632933

Article PDF–2.9M

Select item 263026116.

Lymphocyte-Specific Compensation For XLF/Cernunnos End-Joining Functions In V(D)J Recombination

Gang Li, Frederick W. Alt, Hwei-Ling Cheng, James W. Brush, Peter Goff, Mike M. Murphy, Sonia Franco, Yu Zhang, Shan Zha

Mol Cell. Author manuscript; available in PMC 2009 Mar 5.

Published in final edited form as: Mol Cell. 2008 Sep 5; 31(5): 631–640. doi: 10.1016/j.molcel.2008.07.017

PMCID:: PMC2630261

Article PDF–1.2M

Select item 851641217.

An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development

Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay

eLife. 2021; 10: e69353. Published online 2021 Sep 14. doi: 10.7554/eLife.69353

PMCID:: PMC8516412

Article PDF–10M

Select item 760821918.

ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells

Xiaojing Liu, Tingting Liu, Yafang Shang, Pengfei Dai, Wubing Zhang, Brian J. Lee, Min Huang, Dingpeng Yang, Qiu Wu, Liu Daisy Liu, Xiaoqi Zheng, Bo O. Zhou, Junchao Dong, Leng-Siew Yeap, Jiazhi Hu, Tengfei Xiao, Shan Zha, Rafael Casellas, X. Shirley Liu, Fei-Long Meng

Cell Res. 2020 Sep; 30(9): 732–744. Published online 2020 Apr 30. doi: 10.1038/s41422-020-0328-3

PMCID:: PMC7608219

Article PDF–4.1M

Select item 576285619.

PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice

Vincent Abramowski, Olivier Etienne, Ramy Elsaid, Junjie Yang, Aurélie Berland, Laetitia Kermasson, Benoit Roch, Stefania Musilli, Jean-Paul Moussu, Karelia Lipson-Ruffert, Patrick Revy, Ana Cumano, François D Boussin, Jean-Pierre de Villartay

Cell Death Differ. 2018 Feb; 25(2): 444–452. Published online 2017 Oct 27. doi: 10.1038/cdd.2017.184