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Select item 92396111.

High expression of N-type calcium channel indicates a favorable prognosis in gliomas

Guibin Li, Bhaskar Roy, Xiaoqiang Huang, Yafei Mu, Jiecheng Yuan, Yang Xia, Yue Song, Ziyue Peng

Medicine (Baltimore) 2022 Jul 1; 101(26): e29782. Published online 2022 Jun 30. doi: 10.1097/MD.0000000000029782

PMCID:: PMC9239611

Abstract Article PDF–1.5M

Select item 85291742.

Structure of human Ca_v2.2 channel blocked by the pain killer ziconotide

Shuai Gao, Xia Yao, Nieng Yan

Nature. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Nature. 2021 Aug; 596(7870): 143–147. Published online 2021 Jul 7. doi: 10.1038/s41586-021-03699-6

PMCID:: PMC8529174

Abstract Article PDF–2.6M

Select item 78706333.

CACNA1B gene variants in adult-onset isolated focal dystonia

Relu Cocoș, Florina Raicu, Ovidiu Lucian Băjenaru, Iulia Olaru, Laura Dumitrescu, Bogdan Ovidiu Popescu

Neurol Sci. 2021; 42(3): 1113–1117. Published online 2020 Oct 13. doi: 10.1007/s10072-020-04778-8

PMCID:: PMC7870633

Abstract Article PDF–1.0M

Select item 65070394.

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia

Kathleen M. Gorman, Esther Meyer, Detelina Grozeva, Egidio Spinelli, Amy McTague, Alba Sanchis-Juan, Keren J. Carss, Emily Bryant, Adi Reich, Amy L. Schneider, Ronit M. Pressler, Michael A. Simpson, Geoff D. Debelle, Evangeline Wassmer, Jenny Morton, Diana Sieciechowicz, Eric Jan-Kamsteeg, Alex R. Paciorkowski, Mary D. King, J. Helen Cross, Annapurna Poduri, Heather C. Mefford, Ingrid E. Scheffer, Tobias B. Haack, Gary McCullagh, Deciphering Developmental Disorders Study, UK10K Consortium, NIHR BioResource, John J. Millichap, Gemma L. Carvill, Jill Clayton-Smith, Eamonn R. Maher, F. Lucy Raymond, Manju A. Kurian

Am J Hum Genet. 2019 May 2; 104(5): 948–956. Published online 2019 Apr 11. doi: 10.1016/j.ajhg.2019.03.005

PMCID:: PMC6507039

Abstract Article PDF–887K

Select item 52398365.

CACNA1B (Ca_v2.2) Overexpression and Its Association with Clinicopathologic Characteristics and Unfavorable Prognosis in Non-Small Cell Lung Cancer

Xiaoyu Zhou, Wei Wang, Shu Zhang, Xudong Wang, Zhiyuan Tang, Jun Gu, Jun Li, Jianan Huang

Dis Markers. 2017; 2017: 6136401. Published online 2017 Jan 3. doi: 10.1155/2017/6136401

PMCID:: PMC5239836

Abstract Article PDF–2.5M

Select item 48174046.

CACNA1B mutation is linked to unique myoclonus-dystonia syndrome

Justus L. Groen, Arturo Andrade, Katja Ritz, Hamid Jalalzadeh, Martin Haagmans, Ted E.J. Bradley, Aldo Jongejan, Dineke S. Verbeek, Peter Nürnberg, Sylvia Denome, Raoul C.M. Hennekam, Diane Lipscombe, Frank Baas, Marina A.J. Tijssen

Hum Mol Genet. 2015 Feb 15; 24(4): 987–993. Published online 2014 Oct 8. doi: 10.1093/hmg/ddu513

PMCID:: PMC4817404

Abstract Article PDF–494K

Select item 46232307.

Alternative Splicing in Ca_V2.2 Regulates Neuronal Trafficking via Adaptor Protein Complex-1 Adaptor Protein Motifs

Natsuko Macabuag, Annette C. Dolphin

J Neurosci. 2015 Oct 28; 35(43): 14636–14652. doi: 10.1523/JNEUROSCI.3034-15.2015

PMCID:: PMC4623230

Abstract Article PDF–4.4M

Select item 45508228.

The CACNA1B R1389H variant is not associated with myoclonus-dystonia in a large European multicentric cohort

Niccolo E. Mencacci, Léa R'bibo, Sara Bandres-Ciga, Miryam Carecchio, Giovanna Zorzi, Nardo Nardocci, Barbara Garavaglia, Amit Batla, Kailash P. Bhatia, Alan M. Pittman, John Hardy, Anne Weissbach, Christine Klein, Thomas Gasser, Ebba Lohmann, Nicholas W. Wood

Hum Mol Genet. 2015 Sep 15; 24(18): 5326–5329. Published online 2015 Jul 8. doi: 10.1093/hmg/ddv255

PMCID:: PMC4550822

Abstract Article PDF–87K

Select item 41789379.

Voltage-dependent regulation of Ca_V2.2 channels by G_q-coupled receptor is facilitated by membrane-localized β subunit

Dongil Keum, Christina Baek, Dong-Il Kim, Hae-Jin Kweon, Byung-Chang Suh

J Gen Physiol. 2014 Oct; 144(4): 297–309. doi: 10.1085/jgp.201411245

PMCID:: PMC4178937

Abstract Article PDF–2.5M

Select item 361564810.

Nanodomain Ca²⁺ of Ca²⁺ channels detected by a tethered genetically encoded Ca²⁺ sensor

Lai Hock Tay, Ivy E. Dick, Wanjun Yang, Marco Mank, Oliver Griesbeck, David T. Yue

Nat Commun. Author manuscript; available in PMC 2013 Apr 3.

Published in final edited form as: Nat Commun. 2012; 3: 778. Published online 2012 Apr 10. doi: 10.1038/ncomms1777

PMCID:: PMC3615648

Abstract Article PDF–1.7M

Select item 257033111.

Orientation of the Calcium Channel β Relative to the α₁2.2 Subunit Is Critical for Its Regulation of Channel Activity

Iuliia Vitko, Aleksandr Shcheglovitov, Joel P. Baumgart, Imilla I. Arias-Olguín, Janet Murbartián, Juan Manuel Arias, Edward Perez-Reyes

PLoS One. 2008; 3(10): e3560. Published online 2008 Oct 29. doi: 10.1371/journal.pone.0003560

PMCID:: PMC2570331

Abstract Article PDF–660K

Select item 199564112.

Alternative splicing in the C-terminus of Ca_V2.2 controls expression and gating of N-type calcium channels

Andrew J Castiglioni, Jesica Raingo, Diane Lipscombe

J Physiol. 2006 Oct 1; 576(Pt 1): 119–134. Published online 2006 Jul 20. doi: 10.1113/jphysiol.2006.115030

PMCID:: PMC1995641

Abstract Article PDF–880K

Select item 181776813.

The importance of occupancy rather than affinity of Ca_Vβ subunits for the calcium channel I–II linker in relation to calcium channel function

Adrian J Butcher, Jérôme Leroy, Mark W Richards, Wendy S Pratt, Annette C Dolphin

J Physiol. 2006 Jul 15; 574(Pt 2): 387–398. Published online 2006 Apr 20. doi: 10.1113/jphysiol.2006.109744

PMCID:: PMC1817768

Abstract Article PDF–988K

Select item 130234214.

Mechanosensitivity of N-type calcium channel currents.

Barbara Calabrese, Iustin V Tabarean, Peter Juranka, Catherine E Morris

Biophys J. 2002 Nov; 83(5): 2560–2574. doi: 10.1016/S0006-3495(02)75267-3

PMCID:: PMC1302342

Summary PDF–361K

Select item 544510715.

Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel

Kang Zhang, Zhe Zhao, Liting Lan, Xiaoli Wei, Liyun Wang, Xiaoyan Liu, Haitao Yan, Jianquan Zheng

Front Pharmacol. 2017; 8: 302. Published online 2017 May 26. doi: 10.3389/fphar.2017.00302

PMCID:: PMC5445107

Abstract Article PDF–6.1M

Select item 334965916.

Distinct RGK GTPases Differentially Use α₁- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit Ca_V1.2/Ca_V2.2 Channels

Tingting Yang, Akil Puckerin, Henry M. Colecraft

PLoS One. 2012; 7(5): e37079. Published online 2012 May 10. doi: 10.1371/journal.pone.0037079

PMCID:: PMC3349659

Abstract Article PDF–1.0M

Select item 950004517.

Ca_v2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization

Ying Xue, Min Li, Jie Hu, Yuanlin Song, Wei Guo, Changhong Miao, Di Ge, Yingyong Hou, Xuefei Wang, Xingxu Huang, Tianshu Liu, Xiaoping Zhang, Qihong Huang

Cell Death Dis. 2022 Sep; 13(9): 812. Published online 2022 Sep 22. doi: 10.1038/s41419-022-05174-0

PMCID:: PMC9500045

Abstract Article PDF–4.3M

Select item 339067018.

γ-Aminobutyric Acid Type B (GABA_B) Receptor Expression Is Needed for Inhibition of N-type (Ca_v2.2) Calcium Channels by Analgesic α-Conotoxins

Hartmut Cuny, Andrew de Faoite, Thuan G. Huynh, Takahiro Yasuda, Géza Berecki, David J. Adams

J Biol Chem. 2012 Jul 6; 287(28): 23948–23957. Published online 2012 May 21. doi: 10.1074/jbc.M112.342998

PMCID:: PMC3390670

Abstract Article PDF–1.2M

Select item 330753319.

Synaptic Targeting of N-Type Calcium Channels in Hippocampal Neurons

Anton Maximov, Ilya Bezprozvanny

J Neurosci. 2002 Aug 15; 22(16): 6939–6952. doi: 10.1523/JNEUROSCI.22-16-06939.2002

PMCID:: PMC3307533

Abstract Article PDF–1.0M

Select item 397008820.

Gene-wide analyses of genome-wide association datasets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

V. Moskvina, N. Craddock, P. Holmans, I. Nikolov, J.S. Pahwa, E. Green, Wellcome Trust Case Control Consortium, M.J. Owen, M.C. O’Donovan

Mol Psychiatry. Author manuscript; available in PMC 2014 Mar 31.

Published in final edited form as: Mol Psychiatry. 2009 Mar; 14(3): 252–260. Published online 2008 Dec 9. doi: 10.1038/mp.2008.133

PMCID:: PMC3970088

Abstract Article PDF–598K

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