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Select item 102898961.

A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response

Jonas P. Koch, Selina M. Roth, Aurélie Quintin, Jacopo Gavini, Eleonora Orlando, Rahel Riedo, Chiara Pozzato, Liana Hayrapetyan, Ruedi Aebersold, Deborah M. Stroka, Daniel M. Aebersold, Matúš Medo, Yitzhak Zimmer, Michaela Medová

Oncogene. 2023; 42(26): 2113–2125. Published online 2023 May 15. doi: 10.1038/s41388-023-02714-6

PMCID:: PMC10289896

Abstract Article PDF–3.3M

Select item 92781432.

Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen

Savannah F. Pedersen, Jack A. Collora, Rachel N. Kim, Kerui Yang, Anya Razmi, Allison A. Catalano, Yang-Hui Jimmy Yeh, Karam Mounzer, Pablo Tebas, Luis J. Montaner, Ya-Chi Ho

J Virol. 2022 Jul; 96(13): e00577-22. Published online 2022 Jun 22. doi: 10.1128/jvi.00577-22

PMCID:: PMC9278143

Abstract Article PDF–3.3M

Select item 44355563.

Variants in Several Genomic Regions Associated with Asperger Disorder

D. Salyakina, D.Q. Ma, J.M. Jaworski, I. Konidari, P.L. Whitehead, R. Henson, D. Martinez, J.L. Robinson, S. Sacharow, H.H. Wright, R.K. Abramson, J.R. Gilbert, M.L. Cuccaro, M.A. Pericak-Vance

Autism Res. Author manuscript; available in PMC 2015 May 18.

Published in final edited form as: Autism Res. 2010 Dec; 3(6): 303–310. doi: 10.1002/aur.158

PMCID:: PMC4435556

Abstract Article PDF–357K

Select item 71420144.

The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically

Zhibin Yu, Jianbo Feng, Wei Wang, Zhiyong Deng, Yan Zhang, Lan Xiao, Zeyou Wang, Changhong Liu, Qing Liu, Shuai Chen, Minghua Wu

Oncogene. 2020; 39(15): 3163–3178. Published online 2020 Feb 13. doi: 10.1038/s41388-020-1206-7

PMCID:: PMC7142014

Abstract Article PDF–5.4M

Select item 75895245.

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1–AKT axis-mediated glycolysis

Wei Gao, Yuliang Zhang, Hongjie Luo, Min Niu, Xiwang Zheng, Wanglai Hu, Jiajia Cui, Xuting Xue, Yunfeng Bo, Fengsheng Dai, Yan Lu, Dongli Yang, Yujia Guo, Huina Guo, Huizheng Li, Yu Zhang, Tao Yang, Li Li, Linshi Zhang, Rui Hou, Shuxin Wen, Changming An, Teng Ma, Lei Jin, Wei Xu, Yongyan Wu

Cell Death Dis. 2020 Oct; 11(10): 919. Published online 2020 Oct 26. doi: 10.1038/s41419-020-03104-6

PMCID:: PMC7589524

Abstract Article PDF–5.2M

Select item 91631886.

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c

Ye Yao, Weijie Ma, Yonghua Guo, Yingyi Liu, Peng Xia, Xiaoling Wu, Yiran Chen, Kunlei Wang, Chengjie Mei, Ganggang Wang, Xiaomian Li, Zhonglin Zhang, Xi Chen, Yufeng Yuan

Oncogenesis. 2022 Dec; 11(1): 31. Published online 2022 Jun 2. doi: 10.1038/s41389-022-00404-8

Correction in:: Oncogenesis. 2023 Dec; 12(1): 27.

PMCID:: PMC9163188

Abstract Article PDF–8.2M

Select item 10879077.

Scanning the human proteome for calmodulin-binding proteins

Xinchun Shen, C. Alexander Valencia, Jack Szostak, Biao Dong, Rihe Liu

Proc Natl Acad Sci U S A. 2005 Apr 26; 102(17): 5969–5974. Published online 2005 Apr 19. doi: 10.1073/pnas.0407928102

Correction in:: Proc Natl Acad Sci U S A. 2005 Jul 5; 102(27): 9734.

PMCID:: PMC1087907

Abstract Article PDF–362K

Select item 72955768.

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137

Fengwen Zhang, Paul D Bieniasz

eLife. 2020; 9: e55806. Published online 2020 Jun 15. doi: 10.7554/eLife.55806

PMCID:: PMC7295576

Abstract Article PDF–4.3M

Select item 66675009.

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF

Rainer W. J. Kaiser, Michael Ignarski, Eric L. Van Nostrand, Christian K. Frese, Manaswita Jain, Sadrija Cukoski, Heide Heinen, Melanie Schaechter, Lisa Seufert, Konstantin Bunte, Peter Frommolt, Patrick Keller, Mark Helm, Katrin Bohl, Martin Höhne, Bernhard Schermer, Thomas Benzing, Katja Höpker, Christoph Dieterich, Gene W. Yeo, Roman-Ulrich Müller, Francesca Fabretti

Sci Rep. 2019; 9: 11071. Published online 2019 Jul 30. doi: 10.1038/s41598-019-47552-3

PMCID:: PMC6667500

Abstract Article PDF–2.8M

Select item 592237710.

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer

Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Rosa García-Díaz, Esther Rodríguez-Belmonte, Lu Yu, Mercedes Pardo, Jyoti S. Choudhary, María Esperanza Cerdán

Oncotarget. 2018 Apr 10; 9(27): 19050–19064. Published online 2018 Apr 10. doi: 10.18632/oncotarget.24887

PMCID:: PMC5922377

Abstract Article PDF–1.7M

Select item 292829211.

The Protein Network Surrounding the Human Telomere Repeat Binding Factors TRF1, TRF2, and POT1

Richard J. Giannone, Hayes W. McDonald, Gregory B. Hurst, Rong-Fong Shen, Yisong Wang, Yie Liu

PLoS One. 2010; 5(8): e12407. Published online 2010 Aug 25. doi: 10.1371/journal.pone.0012407

PMCID:: PMC2928292

Abstract Article PDF–1.3M

Select item 936044312.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

Select item 599379713.

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed

Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3

PMCID:: PMC5993797

Abstract Article PDF–2.9M

Select item 459714614.

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases

Jun Yang, Yingxin Zhao, Mridul Kalita, Xueling Li, Mohammad Jamaluddin, Bing Tian, Chukwudi B. Edeh, John E. Wiktorowicz, Andrzej Kudlicki, Allan R. Brasier

Mol Cell Proteomics. 2015 Oct; 14(10): 2701–2721. Published online 2015 Jul 21. doi: 10.1074/mcp.M115.049221

PMCID:: PMC4597146

Abstract Article PDF–4.5M

Select item 584953415.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 435865916.

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

Benjamin A Diner, Tuo Li, Todd M Greco, Marni S Crow, John A Fuesler, Jennifer Wang, Ileana M Cristea

Mol Syst Biol. 2015 Feb; 11(2): 787. Published online 2015 Feb 9. doi: 10.15252/msb.20145808

PMCID:: PMC4358659

Abstract Article PDF–3.6M

Select item 962912117.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 892305718.

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava

Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021

PMCID:: PMC8923057

Abstract Article PDF–2.5M

Select item 860245119.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 509804220.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

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