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Select item 108562631.

Stratification of Colorectal Patients Based on Survival Analysis Shows the Value of Consensus Molecular Subtypes and Reveals the CBLL1 Gene as a Biomarker of CMS2 Tumours

Gloria Alfonsín, Alberto Berral-González, Andrea Rodríguez-Alonso, Macarena Quiroga, Javier De Las Rivas, Angélica Figueroa

Int J Mol Sci. 2024 Feb; 25(3): 1919. Published online 2024 Feb 5. doi: 10.3390/ijms25031919

PMCID:: PMC10856263

Abstract Article PDF–8.3M

Select item 107037702.

CBLL1 is hypomethylated and correlates with cortical thickness in transgender men before gender affirming hormone treatment

Rosa Fernández, Leire Zubiaurre-Elorza, Andrea Santisteban, Natalia Ojeda, Sarah Collet, Meltem Kiyar, Guy T’Sjoen, Sven C. Mueller, Antonio Guillamon, Eduardo Pásaro

Sci Rep. 2023; 13: 21609. Published online 2023 Dec 7. doi: 10.1038/s41598-023-48782-2

PMCID:: PMC10703770

Abstract Article PDF–2.0M

Select item 65584513.

CBLL1 is highly expressed in non‐small cell lung cancer and promotes cell proliferation and invasion

Linping Hui, Siyang Zhang, Muli Wudu, Hongjiu Ren, Yitong Xu, Qingfu Zhang, Xueshan Qiu

Thorac Cancer. 2019 Jun; 10(6): 1479–1488. Published online 2019 May 23. doi: 10.1111/1759-7714.13097

PMCID:: PMC6558451

Abstract Article PDF–3.5M

Select item 58238654.

Hakai overexpression effectively induces tumour progression and metastasis in vivo

Raquel Castosa, Olaia Martinez-Iglesias, Daniel Roca-Lema, Alba Casas-Pais, Andrea Díaz-Díaz, Pilar Iglesias, Isabel Santamarina, Begoña Graña, Lourdes Calvo, Manuel Valladares-Ayerbes, Ángel Concha, Angélica Figueroa

Sci Rep. 2018; 8: 3466. Published online 2018 Feb 22. doi: 10.1038/s41598-018-21808-w

PMCID:: PMC5823865

Abstract Article PDF–4.3M

Select item 41621665.

Dimeric Switch of Hakai-truncated Monomers during Substrate Recognition: INSIGHTS FROM SOLUTION STUDIES AND NMR STRUCTURE

Manjeet Mukherjee, Fan Jing-Song, Sarath Ramachandran, Graeme R. Guy, J. Sivaraman

J Biol Chem. 2014 Sep 12; 289(37): 25611–25623. Published online 2014 Jul 29. doi: 10.1074/jbc.M114.592840

PMCID:: PMC4162166

Abstract Article PDF–3.6M

Select item 30679536.

Appraising the Roles of CBLL1 and the Ubiquitin/Proteasome System for Flavivirus Entry and Replication

Maria-Dolores Fernandez-Garcia, Laurent Meertens, Matteo Bonazzi, Pascale Cossart, Fernando Arenzana-Seisdedos, Ali Amara

J Virol. 2011 Mar; 85(6): 2980–2989. Published online 2010 Dec 29. doi: 10.1128/JVI.02483-10

PMCID:: PMC3067953

Abstract Article PDF–1.6M

Select item 70171487.

Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability

Andrea Díaz-Díaz, Daniel Roca-Lema, Alba Casas-Pais, Gabriela Romay, Giovanni Colombo, Ángel Concha, Begoña Graña, Angélica Figueroa

Cancers (Basel) 2020 Jan; 12(1): 215. Published online 2020 Jan 15. doi: 10.3390/cancers12010215

PMCID:: PMC7017148

Abstract Article PDF–4.1M

Select item 35275648.

miR-203 Regulates Cell Proliferation through Its Influence on Hakai Expression

Vanessa Abella, Manuel Valladares, Teresa Rodriguez, Mar Haz, Moisés Blanco, Nuria Tarrío, Pilar Iglesias, Luís A. Aparicio, Angélica Figueroa

PLoS One. 2012; 7(12): e52568. Published online 2012 Dec 20. doi: 10.1371/journal.pone.0052568

PMCID:: PMC3527564

Abstract Article PDF–1.5M

Select item 111593669.

Hakai acts as a coregulator of estrogen receptor alpha in breast cancer cells

Eun‐Yeung Gong, Eunsook Park, Keesook Lee

Cancer Sci. 2010 Sep; 101(9): 2019–2025. Published online 2010 Jun 1. doi: 10.1111/j.1349-7006.2010.01636.x

PMCID:: PMC11159366

Abstract Article PDF–331K

Select item 271957110.

Novel Roles of Hakai in Cell Proliferation and Oncogenesis

Angélica Figueroa, Hirokazu Kotani, Yoshinobu Toda, Krystyna Mazan-Mamczarz, Eva-Christina Mueller, Albrecht Otto, Lena Disch, Mark Norman, Rasika Mohan Ramdasi, Mohammed Keshtgar, Myriam Gorospe, Yasuyuki Fujita

Mol Biol Cell. 2009 Aug 1; 20(15): 3533–3542. doi: 10.1091/mbc.E08-08-0845

PMCID:: PMC2719571

Abstract Article PDF–2.1M

Select item 605579411.

Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Meng Lu, Jiao Wu, Zhi‐Wei Hao, Yu‐Kui Shang, Jing Xu, Gang Nan, Xia Li, Zhi‐Nan Chen, Huijie Bian

Hepatology. 2018 Jul; 68(1): 317–332. Published online 2018 Mar 23. doi: 10.1002/hep.29798

PMCID:: PMC6055794

Abstract Article PDF–1.3M

Select item 320365412.

Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding, Jian-Guo Geng

Cell Res. 2011 Apr; 21(4): 609–626. Published online 2011 Feb 1. doi: 10.1038/cr.2011.17

Correction in:: Cell Res. 2011 Jun; 21(6): 992.

PMCID:: PMC3203654

Abstract Article PDF–2.5M

Select item 357319813.

The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC

Joana Figueiredo, Ola Söderberg, Joana Simões-Correia, Karin Grannas, Gianpaolo Suriano, Raquel Seruca

Eur J Hum Genet. 2013 Mar; 21(3): 301–309. Published online 2012 Aug 1. doi: 10.1038/ejhg.2012.159

PMCID:: PMC3573198

Abstract Article PDF–3.4M

Select item 337103814.

Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent

David Smyth, Gabriella Leung, Maria Fernando, Derek M. McKay

PLoS One. 2012; 7(6): e38441. Published online 2012 Jun 8. doi: 10.1371/journal.pone.0038441

PMCID:: PMC3371038

Abstract Article PDF–2.8M

Select item 329800215.

Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin

Manjeet Mukherjee, Soah Yee Chow, Permeen Yusoff, J Seetharaman, Cherlyn Ng, Saravanan Sinniah, Xiao Woon Koh, Nur Farehan M Asgar, Dan Li, Daniel Yim, Rebecca A Jackson, Jingxi Yew, Jingru Qian, Audrey Iyu, Yoon Pin Lim, Xingding Zhou, Siu Kwan Sze, Graeme R Guy, J Sivaraman

EMBO J. 2012 Mar 7; 31(5): 1308–1319. Published online 2012 Jan 17. doi: 10.1038/emboj.2011.496

PMCID:: PMC3298002

Abstract Article PDF–3.0M

Select item 753591916.

PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells

Yueli Shi, Xinyu Wang, Zhiyong Xu, Ying He, Chunyi Guo, Lingjuan He, Caijuan Huan, Changhong Cai, Jiaqi Huang, Jie Zhang, Yiqing Li, Chunlai Zeng, Xue Zhang, Linrun Wang, Yuehai Ke, Hongqiang Cheng

J Biol Chem. 2020 Oct 2; 295(40): 13798–13811. Published online 2020 Jul 31. doi: 10.1074/jbc.RA120.014976

PMCID:: PMC7535919

Abstract Article PDF–6.4M

Select item 958489417.

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease

Daniel Roca-Lema, Macarena Quiroga, Vineeta Khare, Andrea Díaz-Díaz, Aida Barreiro-Alonso, Andrea Rodríguez-Alonso, Ángel Concha, Gabriela Romay, M. Esperanza Cerdán, Christoph Gasche, Angélica Figueroa

Sci Rep. 2022; 12: 17571. Published online 2022 Oct 20. doi: 10.1038/s41598-022-22295-w

PMCID:: PMC9584894

Abstract Article PDF–2.5M

Select item 689239318.

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2019 Dec 4.

Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008

PMCID:: PMC6892393

Abstract Article PDF–1.7M

Select item 399653719.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 509804220.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

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