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Select item 100504151.

Evolving landscape of PD-L2: bring new light to checkpoint immunotherapy

Yuqing Wang, Jiang Du, Zhenyue Gao, Haoyang Sun, Mei Mei, Yu Wang, Yu Ren, Xuan Zhou

Br J Cancer. 2023 Mar 30; 128(7): 1196–1207. Published online 2022 Dec 15. doi: 10.1038/s41416-022-02084-y

PMCID:: PMC10050415

Abstract Article PDF–1.2M

Select item 95463572.

Exome sequencing identifies PD‐L2 as a potential predisposition gene for lymphoma

Jianming Shao, Lei Gao, Marco L. Leung, Bailey Gallinger, Cara Inglese, M. Stephen Meyn, Daniela Del Gaudio, Soma Das, Zejuan Li

Hematol Oncol. 2022 Aug; 40(3): 475–478. Published online 2022 May 29. doi: 10.1002/hon.3033

PMCID:: PMC9546357

Abstract Article PDF–625K

Select item 77491403.

Prognostic relevance of programmed cell death 1 ligand 2 (PDCD1LG2/PD-L2) in patients with advanced stage colon carcinoma treated with chemotherapy

Kevin Chih-Yang Huang, Shu-Fen Chiang, Tsung-Wei Chen, William Tzu-Liang Chen, Pei-Chen Yang, Tao-Wei Ke, K. S. Clifford Chao

Sci Rep. 2020; 10: 22330. Published online 2020 Dec 18. doi: 10.1038/s41598-020-79419-3

PMCID:: PMC7749140

Abstract Article PDF–2.7M

Select item 73184784.

Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma

Friederike Hoffmann, Romina Zarbl, Dennis Niebel, Judith Sirokay, Anne Fröhlich, Christian Posch, Tobias A. W. Holderried, Peter Brossart, Gonzalo Saavedra, Pia Kuster, Sebastian Strieth, Gerrit H. Gielen, Sandra S. Ring, Jörn Dietrich, Torsten Pietsch, Lukas Flatz, Glen Kristiansen, Jennifer Landsberg, Dimo Dietrich

Clin Epigenetics. 2020; 12: 94. Published online 2020 Jun 26. doi: 10.1186/s13148-020-00883-9

PMCID:: PMC7318478

Abstract Article PDF–1.0M

Select item 71567845.

Cisplatin‐induced programmed cell death ligand‐2 expression is associated with metastasis ability in oral squamous cell carcinoma

Shunichi Sudo, Hiroshi Kajiya, Shinji Okano, Mina Sasaki, Yuri Katsumata, Jun Ohno, Tetsuro Ikebe, Akimitsu Hiraki, Koji Okabe

Cancer Sci. 2020 Apr; 111(4): 1113–1123. Published online 2020 Feb 29. doi: 10.1111/cas.14336

PMCID:: PMC7156784

Abstract Article PDF–1.0M

Select item 71359846.

The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

Elliot A. Philips, Antonio Garcia-España, Anna S. Tocheva, Ian M. Ahearn, Kieran R. Adam, Ruimin Pan, Adam Mor, Xiang-Peng Kong

J Biol Chem. 2020 Apr 3; 295(14): 4372–4380. Published online 2019 Dec 27. doi: 10.1074/jbc.AC119.011747

PMCID:: PMC7135984

Abstract Article PDF–3.2M

Select item 67168767.

A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma

Yiyin Zhang, Jin Xu, Jie Hua, Jiang Liu, Chen Liang, Qingcai Meng, Miaoyan Wei, Bo Zhang, Xianjun Yu, Si Shi

J Immunother Cancer. 2019; 7: 233. Published online 2019 Aug 29. doi: 10.1186/s40425-019-0703-0

PMCID:: PMC6716876

Abstract Article PDF–6.9M

Select item 64230108.

Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways

Tingting Ren, Bingxin Zheng, Yi Huang, Shidong Wang, Xing Bao, Kuisheng Liu, Wei Guo

Cell Death Dis. 2019 Apr; 10(4): 261. Published online 2019 Mar 18. doi: 10.1038/s41419-019-1497-1

PMCID:: PMC6423010

Abstract Article PDF–3.9M

Select item 63676109.

Association of a PD-L2 Gene Polymorphism with Chronic Lymphatic Filariasis in a South Indian Cohort

Gopinath Venugopal, Noëlle L. O’Regan, Subash Babu, Ralf R. Schumann, Aparna Srikantam, Roswitha Merle, Susanne Hartmann, Svenja Steinfelder

Am J Trop Med Hyg. 2019 Feb; 100(2): 344–350. Published online 2018 Dec 25. doi: 10.4269/ajtmh.18-0731

PMCID:: PMC6367610

Abstract Article PDF–121K

Select item 566817710.

Tumor PDCD1LG2 (PD-L2) expression and the lymphocytic reaction to colorectal cancer

Yohei Masugi, Reiko Nishihara, Tsuyoshi Hamada, Mingyang Song, Annacarolina da Silva, Keisuke Kosumi, Mancang Gu, Yan Shi, Wanwan Li, Li Liu, Daniel Nevo, Kentaro Inamura, Yin Cao, Xiaoyun Liao, Katsuhiko Nosho, Andrew T. Chan, Marios Giannakis, Adam J. Bass, F. Stephen Hodi, Gordon J. Freeman, Scott J. Rodig, Charles S. Fuchs, Zhi Rong Qian, Jonathan A. Nowak, Shuji Ogino

Cancer Immunol Res. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Immunol Res. 2017 Nov; 5(11): 1046–1055. Published online 2017 Oct 16. doi: 10.1158/2326-6066.CIR-17-0122

PMCID:: PMC5668177

Abstract Article PDF–1.0M

Select item 499497011.

Expression of Programmed Cell Death 1 Ligand 2 (PD-L2) is a Distinguishing Feature of Primary Mediastinal (Thymic) Large B-cell Lymphoma and Associated with PDCD1LG2 Copy Gain

Min Shi, Margaretha GM Roemer, Bjoern Chapuy, Xiaoyun Liao, Heather Sun, Geraldine S. Pinkus, Margaret A. Shipp, Gordon J. Freeman, Scott J. Rodig

Am J Surg Pathol. Author manuscript; available in PMC 2016 Aug 23.

Published in final edited form as: Am J Surg Pathol. 2014 Dec; 38(12): 1715–1723. doi: 10.1097/PAS.0000000000000297

PMCID:: PMC4994970

Abstract Article PDF–1.4M

Select item 459677312.

Epithelial PD-L2 expression marks Barrett's Esophagus and Esophageal Adenocarcinoma

Sarah Derks, Katie S. Nason, Xiaoyun Liao, Matthew D. Stachler, Kevin X. Liu, Jie Bin Liu, Ewa Sicinska, Michael S. Goldberg, Gordon J. Freeman, Scott J. Rodig, Jon M. Davison, Adam J. Bass

Cancer Immunol Res. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Cancer Immunol Res. 2015 Oct; 3(10): 1123–1129. Published online 2015 Jun 16. doi: 10.1158/2326-6066.CIR-15-0046

PMCID:: PMC4596773

Abstract Article PDF–619K

Select item 453919913.

Enhancement of Programmed Death Ligand 2 on Hepatitis C Virus Infected Hepatocytes by Calcineurin Inhibitors

Kazuko Koike, Akinobu Takaki, Takahito Yagi, Yoshiaki Iwasaki, Tetsuya Yasunaka, Hiroshi Sadamori, Susumu Shinoura, Yuzo Umeda, Ryuichi Yoshida, Daisuke Sato, Daisuke Nobuoka, Masashi Utsumi, Yasuhiro Miyake, Fusao Ikeda, Hidenori Shiraha, Toshiyoshi Fujiwara, Kazuhide Yamamoto

Transplantation. 2015 Jul; 99(7): 1447–1454. Published online 2015 Jul 6. doi: 10.1097/TP.0000000000000572

PMCID:: PMC4539199

Abstract Article PDF–1.4M

Select item 297506314.

No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation

Katharina Pfistershammer, Christoph Klauser, Winfried F. Pickl, Johannes Stöckl, Gerhard Zlabinger, Otto Majdic, Peter Steinberger

Eur J Immunol. Author manuscript; available in PMC 2010 Nov 8.

Published in final edited form as: Eur J Immunol. 2006 May; 36(5): 1104–1113. doi: 10.1002/eji.200535344

PMCID:: PMC2975063

Abstract Article PDF–4.7M

Select item 1099110915.

An alternatively spliced PD-L1 isoform PD-L1∆3, and PD-L2 expression in breast cancers: implications for eligibility scoring and immunotherapy response

Didem Naz Dioken, Ibrahim Ozgul, Irem Yilmazbilek, Mustafa Cengiz Yakicier, Ezgi Karaca, Ayse Elif Erson-Bensan

Cancer Immunol Immunother. 2023 Dec; 72(12): 4065–4075. Published online 2023 Sep 28. doi: 10.1007/s00262-023-03543-y

PMCID:: PMC10991109

Abstract Article PDF–2.2M

Select item 1056887916.

Cholinergic signaling influences the expression of immune checkpoint inhibitors, PD-L1 and PD-L2, and tumor hallmarks in human colorectal cancer tissues and cell lines

Nyanbol Kuol, Janusz Godlewski, Zbigniew Kmiec, Sara Vogrin, Sarah Fraser, Vasso Apostolopoulos, Kulmira Nurgali

BMC Cancer. 2023; 23: 971. Published online 2023 Oct 12. doi: 10.1186/s12885-023-11410-3

PMCID:: PMC10568879

Abstract Article PDF–10M

Select item 1006063817.

Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment

Jingfang Lv, Zheng Jiang, Junhu Yuan, Meng Zhuang, Xu Guan, Hengchang Liu, Yefeng Yin, Yiming Ma, Zheng Liu, Hongying Wang, Xishan Wang

Front Immunol. 2023; 14: 1093716. Published online 2023 Mar 16. doi: 10.3389/fimmu.2023.1093716

PMCID:: PMC10060638

Abstract Article PDF–15M

Select item 995294818.

Expression of IDO1 and PD-L2 in Patients with Benign Lymphadenopathies and Association with Autoimmune Diseases

Maysaa Abdulla, Christer Sundström, Cecilia Lindskog, Peter Hollander

Biomolecules. 2023 Feb; 13(2): 240. Published online 2023 Jan 27. doi: 10.3390/biom13020240

PMCID:: PMC9952948

Abstract Article PDF–1.7M

Select item 964337319.

FAK promotes stromal PD-L2 expression associated with poor survival in pancreatic cancer

Catherine Davidson, David Taggart, Andrew H. Sims, David W. Lonergan, Marta Canel, Alan Serrels

Br J Cancer. 2022 Nov 9; 127(10): 1893–1905. Published online 2022 Sep 22. doi: 10.1038/s41416-022-01966-5

PMCID:: PMC9643373

Abstract Article PDF–2.5M

Select item 963275720.

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

Marthe Minderman, Avital Amir, Willem Kraan, Esther J. M. Schilder-Tol, Monique E. C. M. Oud, Cornelis G. Scheepstra, Arnold L. Noorduyn, Philip M. Kluin, Marie José Kersten, Marcel Spaargaren, Steven T. Pals

Blood. 2021 Sep 30; 138(13): 1194–1197. doi: 10.1182/blood.2021011366

PMCID:: PMC9632757

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