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Select item 95124041.

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis

Lena Maria Muckenfuss, Anabel Carmen Migenda Herranz, Franziska Maria Boneberg, Marcello Clerici, Martin Jinek

eLife. 2022; 11: e80332. Published online 2022 Sep 8. doi: 10.7554/eLife.80332

PMCID:: PMC9512404

Abstract Article PDF–6.0M

Select item 61149222.

Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis

Sini Skarp, Olli-Pekka Kämäräinen, Gong-Hong Wei, Eveliina Jakkula, Ilkka Kiviranta, Heikki Kröger, Juha Auvinen, Petri Lehenkari, Leena Ala-Kokko, Minna Männikkö

PLoS One. 2018; 13(8): e0203313. Published online 2018 Aug 29. doi: 10.1371/journal.pone.0203313

PMCID:: PMC6114922

Abstract Article PDF–3.2M

Select item 50780893.

Long-term outcomes of imatinib in patients with FIP1L1/PDGFRA associated chronic eosinophilic leukemia: experience of a single center in China

Shi-Qiang Qu, Tie-Jun Qin, Ze-Feng Xu, Yue Zhang, Xiao-Fei Ai, Bing Li, Hong-Li Zhang, Li-Wei Fang, Li-Juan Pan, Nai-Bo Hu, Zhi-Jian Xiao

Oncotarget. 2016 May 31; 7(22): 33229–33236. Published online 2016 Apr 21. doi: 10.18632/oncotarget.8906

PMCID:: PMC5078089

Abstract Article PDF–1.4M

Select item 18994224.

A Case of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia with a Rare FIP1L1 Breakpoint

Frédéric Lambert, Pierre Heimann, Christian Herens, Alain Chariot, Vincent Bours

J Mol Diagn. 2007 Jul; 9(3): 414–419. doi: 10.2353/jmoldx.2007.060196

PMCID:: PMC1899422

Abstract Article PDF–660K

Select item 1646735.

Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome

John H. Griffin, Joey Leung, Rebecca J. Bruner, Michael A. Caligiuri, Roger Briesewitz

Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13): 7830–7835. Published online 2003 Jun 13. doi: 10.1073/pnas.0932698100

PMCID:: PMC164673

Abstract Article PDF–621K

Select item 33277036.

Identification of JAK2 as a Mediator of FIP1L1-PDGFRA-Induced Eosinophil Growth and Function in CEL

Bin Li, Guangsen Zhang, Cui Li, Dan He, Xinying Li, Chunfang Zhang, Faqing Tang, Xiyun Deng, Jingchen Lu, Youhong Tang, Ruijuan Li, Zhuchu Chen, Chaojun Duan

PLoS One. 2012; 7(4): e34912. Published online 2012 Apr 16. doi: 10.1371/journal.pone.0034912

PMCID:: PMC3327703

Abstract Article PDF–2.7M

Select item 57601997.

Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex

Marcello Clerici, Marco Faini, Ruedi Aebersold, Martin Jinek

eLife. 2017; 6: e33111. Published online 2017 Dec 23. doi: 10.7554/eLife.33111

PMCID:: PMC5760199

Abstract Article PDF–1.4M

Select item 14724328.

Activation of FIP1L1-PDGFRα requires disruption of the juxtamembrane domain of PDGFRα and is FIP1L1-independent

Elizabeth H. Stover, Jing Chen, Cedric Folens, Benjamin H. Lee, Nicole Mentens, Peter Marynen, Ifor R. Williams, D. Gary Gilliland, Jan Cools

Proc Natl Acad Sci U S A. 2006 May 23; 103(21): 8078–8083. Published online 2006 May 11. doi: 10.1073/pnas.0601192103

PMCID:: PMC1472432

Abstract Article PDF–1.5M

Select item 11425559.

Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition

Krishnan Venkataraman, Kirk M. Brown, Gregory M. Gilmartin

Genes Dev. 2005 Jun 1; 19(11): 1315–1327. doi: 10.1101/gad.1298605

PMCID:: PMC1142555

Abstract Article PDF–797K

Select item 106155410.

A 57-Nucleotide Upstream Early Polyadenylation Element in Human Papillomavirus Type 16 Interacts with hFip1, CstF-64, hnRNP C1/C2, and Polypyrimidine Tract Binding Protein

Xiaomin Zhao, Daniel Öberg, Margaret Rush, Joanna Fay, Helen Lambkin, Stefan Schwartz

J Virol. 2005 Apr; 79(7): 4270–4288. doi: 10.1128/JVI.79.7.4270-4288.2005

PMCID:: PMC1061554

Abstract Article PDF–736K

Select item 432327211.

Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of pazopanib

Michael L. Maitland, Chun-Fang Xu, Yu-Ching Cheng, Emily Kistner-Griffin, Kathleen A. Ryan, Theodore G. Karrison, Soma Das, Dara Torgerson, Eric Gamazon, Vasiliki Thomeas, Matthew R. Levine, Paul A. Wilson, Nan Bing, Yuan Liu, Lon R. Cardon, Lini N. Pandite, Jeffrey R. O’Connell, Nancy J. Cox, Braxton D. Mitchell, Mark J. Ratain, Alan R. Shuldiner

Clin Cancer Res. Author manuscript; available in PMC 2016 Jan 15.

Published in final edited form as: Clin Cancer Res. 2015 Jan 15; 21(2): 365–372. Published online 2014 Nov 19. doi: 10.1158/1078-0432.CCR-14-1683

PMCID:: PMC4323272

Abstract Article PDF–702K

Select item 575612112.

Molecular mechanisms for CFIm-mediated regulation of mRNA alternative polyadenylation

Yong Zhu, Xiuye Wang, Elmira Forouzmand, Joshua Jeong, Feng Qiao, Gregory A. Sowd, Alan N. Engelman, Xiaohui Xie, Klemens J. Hertel, Yongsheng Shi

Mol Cell. Author manuscript; available in PMC 2019 Jan 4.

Published in final edited form as: Mol Cell. 2018 Jan 4; 69(1): 62–74.e4. Published online 2017 Dec 21. doi: 10.1016/j.molcel.2017.11.031

PMCID:: PMC5756121

Abstract Article PDF–2.4M

Select item 127180413.

Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase

Isabelle Kaufmann, Georges Martin, Arno Friedlein, Hanno Langen, Walter Keller

EMBO J. 2004 Feb 11; 23(3): 616–626. Published online 2004 Jan 29. doi: 10.1038/sj.emboj.7600070

PMCID:: PMC1271804

Abstract Article PDF–580K

Select item 32143514.

Human RNPS1 and Its Associated Factors: a Versatile Alternative Pre-mRNA Splicing Regulator In Vivo

Eiji Sakashita, Sawako Tatsumi, Dieter Werner, Hitoshi Endo, Akila Mayeda

Mol Cell Biol. 2004 Feb; 24(3): 1174–1187. doi: 10.1128/MCB.24.3.1174-1187.2004

Correction in:: Mol Cell Biol. 2004 Apr; 24(7): 3068.

PMCID:: PMC321435

Abstract Article PDF–706K

Select item 266775615.

Inositol 1,4,5-Triphosphate Receptor-binding Protein Released with Inositol 1,4,5-Triphosphate (IRBIT) Associates with Components of the mRNA 3′ Processing Machinery in a Phosphorylation-dependent Manner and Inhibits Polyadenylation

Hélène Kiefer, Akihiro Mizutani, Shun-Ichiro Iemura, Tohru Natsume, Hideaki Ando, Yukiko Kuroda, Katsuhiko Mikoshiba

J Biol Chem. 2009 Apr 17; 284(16): 10694–10705. doi: 10.1074/jbc.M807136200

PMCID:: PMC2667756

Abstract Article PDF–808K

Select item 859794616.

GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma

Qian yun Ge, Jin Chen, Gan xun Li, Xiao long Tan, Jia Song, Deng Ning, Jie Mo, Peng cheng Du, Qiu meng Liu, Hui fang Liang, Ze yang Ding, Xue wu Zhang, Bi xiang Zhang

Clin Transl Med. 2021 Nov; 11(11): e635. Published online 2021 Nov 17. doi: 10.1002/ctm2.635

PMCID:: PMC8597946

Abstract Article PDF–7.3M

Select item 470210317.

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety

Sang Jun Han, Khurshida Begum, Charles E. Foulds, Ross A. Hamilton, Suzanna Bailey, Anna Malovannaya, Doug Chan, Jun Qin, Bert W. O’Malley

Mol Pharmacol. 2016 Jan; 89(1): 14–26. Published online 2016 Jan. doi: 10.1124/mol.115.100925

PMCID:: PMC4702103

Abstract Article PDF–1.6M

Select item 337803518.

DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation

Pierre Close, Philip East, A. Barbara Dirac-Svejstrup, Holger Hartmann, Mark Heron, Sarah Maslen, Alain Chariot, Johannes Söding, Mark Skehel, Jesper Q. Svejstrup

Nature. Author manuscript; available in PMC 2012 Oct 19.

Published in final edited form as: Nature. 2012 Mar 25; 484(7394): 386–389. Published online 2012 Mar 25. doi: 10.1038/nature10925

PMCID:: PMC3378035

Abstract Article PDF–1.2M

Select item 729750819.

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser

Cell Rep. Author manuscript; available in PMC 2020 Jun 16.

Published in final edited form as: Cell Rep. 2019 Sep 24; 28(13): 3435–3449.e5. doi: 10.1016/j.celrep.2019.08.060

PMCID:: PMC7297508

Abstract Article PDF–2.4M

Select item 562237120.

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation

Ruibing Chen, Yun Liu, Hao Zhuang, Baicai Yang, Kaiwen Hei, Mingming Xiao, Chunyu Hou, Huajun Gao, Xinran Zhang, Chenxi Jia, Lingjun Li, Yongmei Li, Ning Zhang

Nucleic Acids Res. 2017 Sep 29; 45(17): 9947–9959. Published online 2017 Jul 10. doi: 10.1093/nar/gkx600

Correction in:: Nucleic Acids Res. 2021 Apr 19; 49(7): 4199–4202.

PMCID:: PMC5622371

Abstract Article PDF–5.6M

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