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Items: 1 to 20 of 279

1.
Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma
Shang Li, Gert Jan Meersma, Jolanta Kupryjanczyk, Steven de Jong, G. Bea A. Wisman
J Transl Med. 2024; 22: 556. Published online 2024 Jun 10. doi: 10.1186/s12967-024-05311-7
PMCID:
PMC11163774
AbstractArticlePDF–4.6M
2.
ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response
Ali Bakr, Giuditta Della Corte, Olivera Veselinov, Simge Kelekçi, Mei-Ju May Chen, Yu-Yu Lin, Gianluca Sigismondo, Marika Iacovone, Alice Cross, Rabail Syed, Yunhee Jeong, Etienne Sollier, Chun- Shan Liu, Pavlo Lutsik, Jeroen Krijgsveld, Dieter Weichenhan, Christoph Plass, Odilia Popanda, Peter Schmezer
Nucleic Acids Res. 2024 Jun 10; 52(10): 5698–5719. Published online 2024 Apr 8. doi: 10.1093/nar/gkae233
PMCID:
PMC11162808
AbstractArticlePDF–7.7M
3.
Deep‐targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma
Menglin Xiao, Xiaoteng Cui, Can Xu, Lei Xin, Jixing Zhao, Shixue Yang, Biao Hong, Yanli Tan, Jie Zhang, Xiang Li, Jie Li, Chunsheng Kang, Chuan Fang
CNS Neurosci Ther. 2024 Apr; 30(4): e14698. Published online 2024 Apr 11. doi: 10.1111/cns.14698
PMCID:
PMC11007544
AbstractArticlePDF–13M
4.
The Role of the AT-Rich Interaction Domain 1A Gene (ARID1A) in Human Carcinogenesis
Jing Jing Li, Cheok Soon Lee
Genes (Basel) 2024 Jan; 15(1): 5. Published online 2023 Dec 19. doi: 10.3390/genes15010005
PMCID:
PMC10815128
AbstractArticlePDF–2.8M
5.
ARID1A deficiency promotes progression and potentiates therapeutic antitumour immunity in hepatitis B virus-related hepatocellular carcinoma
Tao Xing, Li Li, Xiaosong Rao, Jing Zhao, Yiran Chen, Gaoda Ju, Yaping Xu, Xuan Gao, Guilan Dong, Xuefeng Xia, Yanfang Guan, Lingling Zhang, Zhenping Wen, Jun Liang
BMC Gastroenterol. 2024; 24: 11. Published online 2024 Jan 2. doi: 10.1186/s12876-023-03059-w
PMCID:
PMC10759659
AbstractArticlePDF–7.4M
6.
Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
Tao Xing, Li Li, Yiran Chen, Gaoda Ju, Guilan Li, Xiaoyun Zhu, Yubo Ren, Jing Zhao, Zhilei Cheng, Yan Li, Da Xu, Jun Liang
Cell Rep Med. 2023 Nov 21; 4(11): 101264. Published online 2023 Nov 7. doi: 10.1016/j.xcrm.2023.101264
PMCID:
PMC10694624
AbstractArticlePDF–6.5M
7.
Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple‐negative breast cancer to immune checkpoint inhibitors
Xin‐Yu Chen, Bin Li, Ye Wang, Juan Jin, Yu Yang, Lei‐Huan Huang, Meng‐Di Yang, Jian Zhang, Bi‐Yun Wang, Zhi‐Ming Shao, Ting Ni, Sheng‐Lin Huang, Xi‐Chun Hu, Zhong‐Hua Tao
Cancer Commun (Lond) 2023 Sep; 43(9): 1003–1026. Published online 2023 Jul 11. doi: 10.1002/cac2.12465
PMCID:
PMC10508140
AbstractArticlePDF–9.6M
8.
Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells
Sunay Usluer, Pille Hallast, Luca Crepaldi, Yan Zhou, Katie Urgo, Cansu Dincer, Jing Su, Guillaume Noell, Kaur Alasoo, Omar El Garwany, Sebastian S. Gerety, Ben Newman, Oliver M. Dovey, Leopold Parts
Stem Cell Reports. 2023 May 9; 18(5): 1061–1074. Published online 2023 Apr 6. doi: 10.1016/j.stemcr.2023.03.008
PMCID:
PMC10202655
AbstractArticlePDF–4.7M
9.
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
Ni Li, Qiuli Liu, Ying Han, Siyu Pei, Bisheng Cheng, Junyu Xu, Xiang Miao, Qiang Pan, Hanling Wang, Jiacheng Guo, Xuege Wang, Guoying Zhang, Yannan Lian, Wei Zhang, Yi Zang, Minjia Tan, Qintong Li, Xiaoming Wang, Yichuan Xiao, Guohong Hu, Jun Jiang, Hai Huang, Jun Qin
Nat Commun. 2022; 13: 7281. Published online 2022 Nov 26. doi: 10.1038/s41467-022-34871-9
PMCID:
PMC9701216
AbstractArticlePDF–6.4M
10.
Validated biomarker assays confirm ARID1A loss is confounded with MMR deficiency, CD8 TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas
Karolin Heinze, Tayyebeh M. Nazeran, Sandra Lee, Pauline Krämer, Evan S. Cairns, Derek S. Chiu, Samuel C.Y. Leung, Eun Young Kang, Nicola S. Meagher, Catherine J. Kennedy, Jessica Boros, Friedrich Kommoss, Hans-Walter Vollert, Florian Heitze, Andreas du Bois, Philipp Harter, Marcel Grube, Bernhard Kraemer, Annette Staebler, Felix K.F. Kommoss, Sabine Heublein, Hans-Peter Sinn, Naveena Singh, Angela Laslavic, Esther Elishaev, Alex Olawaiye, Kirsten Moysich, Francesmary Modugno, Raghwa Sharma, Alison H. Brand, Paul R. Harnett, Anna DeFazio, Renée T. Fortner, Jan Lubinski, Marcin Lener, Aleksandra Tołoczko-Grabarek, Cezary Cybulski, Helena Gronwald, Jacek Gronwald, Penny Coulson, Mona A El-Bahrawy, Michael E. Jones, Minouk J. Schoemaker, Anthony J. Swerdlow, Kylie L. Gorringe, Ian Campbell, Linda Cook, Simon A. Gayther, Michael E. Carney, Yurii B. Shvetsov, Brenda Y. Hernandez, Lynne R. Wilkens, Marc T. Goodman, Constantina Mateoiu, Anna Linder, Karin Sundfeldt, Linda E. Kelemen, Aleksandra Gentry-Maharaj, Martin Widschwendter, Usha Menon, Kelly L. Bolton, Jennifer Alsop, Mitul Shah, Mercedes Jimenez-Linan, Paul D.P. Pharoah, James D. Brenton, Kara L. Cushing-Haugen, Holly R. Harris, Jennifer A. Doherty, Blake Gilks, Prafull Ghatage, David G. Huntsman, Gregg S. Nelson, Anna V. Tinker, Cheng-Han Lee, Ellen L. Goode, Brad H. Nelson, Susan J. Ramus, Stefan Kommoss, Aline Talhouk, Martin Köbel, Michael S. Anglesio
J Pathol. Author manuscript; available in PMC 2023 Apr 1.
Published in final edited form as: J Pathol. 2022 Apr; 256(4): 388–401. Published online 2022 Feb 7. doi: 10.1002/path.5849
PMCID:
PMC9544180
AbstractArticlePDF–882K
11.
Definitive study shows no association between ARID1A mutation status and clinical outcome in endometriosis‐related ovarian cancers
Saira Khalique, Sarah Nash, Rachael Natrajan
J Pathol. 2022 Sep; 258(1): 1–3. Published online 2022 Jun 29. doi: 10.1002/path.5973
PMCID:
PMC9540905
AbstractArticlePDF–118K
12.
ARID1A-dependent maintenance of H3.3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers
Jake J. Reske, Mike R. Wilson, Brooke Armistead, Shannon Harkins, Cristina Perez, Joel Hrit, Marie Adams, Scott B. Rothbart, Stacey A. Missmer, Asgerally T. Fazleabas, Ronald L. Chandler
BMC Biol. 2022; 20: 209. Published online 2022 Sep 25. doi: 10.1186/s12915-022-01407-y
PMCID:
PMC9509632
AbstractArticlePDF–15M
13.
ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer
Radia M. Johnson, Xueping Qu, Chu-Fang Lin, Ling-Yuh Huw, Avinashnarayan Venkatanarayan, Ethan Sokol, Fang-Shu Ou, Nnamdi Ihuegbu, Oliver A. Zill, Omar Kabbarah, Lisa Wang, Richard Bourgon, Felipe de Sousa e Melo, Chris Bolen, Anneleen Daemen, Alan P. Venook, Federico Innocenti, Heinz-Josef Lenz, Carlos Bais
Nat Commun. 2022; 13: 5478. Published online 2022 Sep 19. doi: 10.1038/s41467-022-33172-5
PMCID:
PMC9482920
AbstractArticlePDF–1.4M
14.
ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors
Hasibur Rehman, Darshan S. Chandrashekar, Chakravarthi Balabhadrapatruni, Saroj Nepal, Sai Akshaya Hodigere Balasubramanya, Abigail K. Shelton, Kasey R. Skinner, Ai-Hong Ma, Ting Rao, Sumit Agarwal, Marie-Lisa Eich, Alyncia D. Robinson, Gurudatta Naik, Upender Manne, George J. Netto, C. Ryan Miller, Chong-xian Pan, Guru Sonpavde, Sooryanarayana Varambally, James E. Ferguson, III
JCI Insight. 2022 Aug 22; 7(16): e155899. Published online 2022 Aug 22. doi: 10.1172/jci.insight.155899
PMCID:
PMC9462490
AbstractArticlePDF–9.3M
15.
The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling
Sham Jdeed, Edina Erdős, Bálint L. Bálint, Iván P. Uray
Mol Cancer Res. 2022 Jul 6; 20(7): 1071–1082. Published online 2022 Mar 23. doi: 10.1158/1541-7786.MCR-21-0961
PMCID:
PMC9381091
AbstractArticlePDF–1.3M
16.
Therapeutic significance of ARID1A mutation in bladder cancer
Marina Conde, Ian J. Frew
Neoplasia. 2022 Sep; 31: 100814. Published online 2022 Jun 21. doi: 10.1016/j.neo.2022.100814
PMCID:
PMC9234250
AbstractArticlePDF–747K
17.
Systemic and ocular manifestations of a patient with mosaic ARID1A-associated Coffin-Siris syndrome and review of select mosaic conditions with ophthalmic manifestations
Virginia Miraldi Utz, Diana S. Brightman, Monica A. Sandoval, Robert B. Hufnagel, Howard M. Saal
Am J Med Genet C Semin Med Genet. Author manuscript; available in PMC 2022 Feb 2.
Published in final edited form as: Am J Med Genet C Semin Med Genet. 2020 Sep; 184(3): 644–655. Published online 2020 Sep 5. doi: 10.1002/ajmg.c.31839
PMCID:
PMC8808370
AbstractArticlePDF–724K
18.
The effects of ARID1A mutations on colorectal cancer and associations with PD‐L1 expression by stromal cells
Tomohiro Kamori, Eiji Oki, Yoshifumi Shimada, Qingjiang Hu, Yuichi Hisamatsu, Koji Ando, Mototsugu Shimokawa, Toshifumi Wakai, Yoshinao Oda, Masaki Mori
Cancer Rep (Hoboken) 2022 Jan; 5(1): e1420. Published online 2021 May 27. doi: 10.1002/cnr2.1420
PMCID:
PMC8789618
AbstractArticlePDF–5.7M
19.
ARID1A Is a Prognostic Biomarker and Associated with Immune Infiltrates in Hepatocellular Carcinoma
Yuanyuan Feng, Xinfang Tang, Changcheng Li, Ying Su, Xiaoyu Wang, Ning Li, Anna Zhang, Feng Jiang, Chuyan Wu
Can J Gastroenterol Hepatol. 2022; 2022: 3163955. Published online 2022 Jan 4. doi: 10.1155/2022/3163955
PMCID:
PMC8752298
AbstractArticlePDF–2.2M
20.
Loss of ARID1A promotes epithelial-mesenchymal transition and sensitizes pancreatic tumors to proteotoxic stress
Hideo Tomihara, Federica Carbone, Luigi Perelli, Justin K Huang, Melinda Soeung, Johnathon L Rose, Frederick S Robinson, Yonathan Lissanu Deribe, Ningping Feng, Mitsunobu Takeda, Akira Inoue, Edoardo Del Poggetto, Angela K Deem, Anirban Maitra, Pavlos Msaouel, Nizar M Tannir, Giulio F Draetta, Andrea Viale, Andrea Viale, Timothy P Heffernan, Christopher A Bristow, Alessandro Carugo, Giannicola Genovese
Cancer Res. Author manuscript; available in PMC 2022 Jan 5.
Published in final edited form as: Cancer Res. 2021 Jan 15; 81(2): 332–343. Published online 2020 Nov 6. doi: 10.1158/0008-5472.CAN-19-3922
PMCID:
PMC8728103
AbstractArticlePDF–2.4M

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