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Select item 109565181.

Validation of CDC45 as a novel biomarker for diagnosis and prognosis of gastric cancer

Lihua Wu, Gan Gao, Hui Mi, Zhou Luo, Zheng Wang, Yongdong Liu, Liangyan Wu, Haihua Long, Yongqi Shen

PeerJ. 2024; 12: e17130. Published online 2024 Mar 18. doi: 10.7717/peerj.17130

PMCID:: PMC10956518

Abstract Article PDF–19M

Select item 94789882.

Systematic pan-cancer analysis identifies CDC45 as having an oncogenic role in human cancers

Yalin Lu, Xingjie Chen, Fang Liu, Hao Yu, Yu Zhang, Kangjie Du, Yang Nan, Qiang Huang

Oncol Rep. 2022 Oct; 48(4): 185. Published online 2022 Sep 8. doi: 10.3892/or.2022.8400

PMCID:: PMC9478988

Abstract Article PDF–14M

Select item 79192313.

Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes

Hui-Ping Lu, Xiu-Fang Du, Jian-Di Li, Su-Ning Huang, Rong-Quan He, Hua-Yu Wu, Ming-Fen Li, Wei-Zi Wu, Ji-Tian Chen, Wei-Jia Mo, Gang Chen

Med Sci Monit. 2021; 27: e928800-1–e928800-11. Prepublished online 2020 Dec 24. Published online 2021 Feb 24. doi: 10.12659/MSM.928800

PMCID:: PMC7919231

Abstract Article PDF–3.8M

Select item 71972304.

Pathogenic variants in CDC45 on the remaining allele in patients with a chromosome 22q11.2 deletion result in a novel autosomal recessive condition

Marta Unolt, Molka Kammoun, Beata Nowakowska, Gail E. Graham, T. Blaine Crowley, Matthew S. Hestand, Wolfram Demaerel, Maciej Geremek, Beverly S. Emanuel, Elaine H. Zackai, Joris R. Vermeesch, Donna McDonald-McGinn

Genet Med. 2020; 22(2): 326–335. Published online 2019 Sep 2. doi: 10.1038/s41436-019-0645-4

PMCID:: PMC7197230

Abstract Article PDF–720K

Select item 68513075.

Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45)

Abbey L. Perl, Caitlin M. O'Connor, Pengyan Fa, Franklin Mayca Pozo, Junran Zhang, Youwei Zhang, Goutham Narla

J Biol Chem. 2019 Nov 8; 294(45): 17043–17059. Published online 2019 Sep 27. doi: 10.1074/jbc.RA119.010432

PMCID:: PMC6851307

Abstract Article PDF–5.5M

Select item 53895706.

Cdc45-induced loading of human RPA onto single-stranded DNA

Anna Szambowska, Ingrid Tessmer, Piotr Prus, Bernhard Schlott, Helmut Pospiech, Frank Grosse

Nucleic Acids Res. 2017 Apr 7; 45(6): 3217–3230. Published online 2017 Jan 18. doi: 10.1093/nar/gkw1364

PMCID:: PMC5389570

Abstract Article PDF–4.2M

Select item 50054527.

Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis

Aimee L. Fenwick, Maciej Kliszczak, Fay Cooper, Jennie Murray, Luis Sanchez-Pulido, Stephen R.F. Twigg, Anne Goriely, Simon J. McGowan, Kerry A. Miller, Indira B. Taylor, Clare Logan, WGS500 Consortium, Sevcan Bozdogan, Sumita Danda, Joanne Dixon, Solaf M. Elsayed, Ezzat Elsobky, Alice Gardham, Mariette J.V. Hoffer, Marije Koopmans, Donna M. McDonald-McGinn, Gijs W.E. Santen, Ravi Savarirayan, Deepthi de Silva, Olivier Vanakker, Steven A. Wall, Louise C. Wilson, Ozge Ozalp Yuregir, Elaine H. Zackai, Chris P. Ponting, Andrew P. Jackson, Andrew O.M. Wilkie, Wojciech Niedzwiedz, Louise S. Bicknell

Am J Hum Genet. 2016 Jul 7; 99(1): 125–138. Published online 2016 Jun 30. doi: 10.1016/j.ajhg.2016.05.019

PMCID:: PMC5005452

Abstract Article PDF–3.2M

Select item 48893078.

Cdc45 is limiting for replication initiation in humans

Carsten Köhler, Dennis Koalick, Anja Fabricius, Ann Christin Parplys, Kerstin Borgmann, Helmut Pospiech, Frank Grosse

Cell Cycle. 2016; 15(7): 974–985. Published online 2016 Feb 26. doi: 10.1080/15384101.2016.1152424

PMCID:: PMC4889307

Abstract Article PDF–1.2M

Select item 48739809.

Structure of human Cdc45 and implications for CMG helicase function

Aline C. Simon, Vincenzo Sannino, Vincenzo Costanzo, Luca Pellegrini

Nat Commun. 2016; 7: 11638. Published online 2016 May 18. doi: 10.1038/ncomms11638

PMCID:: PMC4873980

Abstract Article PDF–4.3M

Select item 393675110.

DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding

Anna Szambowska, Ingrid Tessmer, Petri Kursula, Christian Usskilat, Piotr Prus, Helmut Pospiech, Frank Grosse

Nucleic Acids Res. 2014 Feb; 42(4): 2308–2319. Published online 2013 Nov 28. doi: 10.1093/nar/gkt1217

PMCID:: PMC3936751

Abstract Article PDF–4.6M

Select item 333490411.

Cell Cycle-Dependent Mobility of Cdc45 Determined in vivo by Fluorescence Correlation Spectroscopy

Ronan Broderick, Sivaramakrishnan Ramadurai, Katalin Tóth, Denisio M. Togashi, Alan G. Ryder, Jörg Langowski, Heinz Peter Nasheuer

PLoS One. 2012; 7(4): e35537. Published online 2012 Apr 19. doi: 10.1371/journal.pone.0035537

PMCID:: PMC3334904

Abstract Article PDF–351K

Select item 328174212.

Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases

Ivet Krastanova, Vincenzo Sannino, Heinz Amenitsch, Opher Gileadi, Francesca M. Pisani, Silvia Onesti

J Biol Chem. 2012 Feb 3; 287(6): 4121–4128. Published online 2011 Dec 6. doi: 10.1074/jbc.M111.285395

PMCID:: PMC3281742

Abstract Article PDF–1.7M

Select item 443925613.

Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin

Jeannine Gerhardt, Gulfem D. Guler, Ellen Fanning

Exp Cell Res. Author manuscript; available in PMC 2016 Jun 10.

Published in final edited form as: Exp Cell Res. 2015 Jun 10; 334(2): 283–293. Published online 2015 Apr 29. doi: 10.1016/j.yexcr.2015.04.014

PMCID:: PMC4439256

Abstract Article PDF–974K

Select item 850171314.

CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis

Rongcai Liu, Weimin Dai, An Wu, Yunping Li

BMC Cancer. 2021; 21: 1090. Published online 2021 Oct 9. doi: 10.1186/s12885-021-08803-7

PMCID:: PMC8501713

Abstract Article PDF–4.3M

Select item 613956815.

Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells

Sumeet Poudel, Jianhong Yao, Michael G. Kemp, Michael Leffak

J Biol Chem. 2018 Sep 14; 293(37): 14497–14506. Published online 2018 Jul 23. doi: 10.1074/jbc.RA118.004519

PMCID:: PMC6139568

Abstract Article PDF–685K

Select item 31075716.

Direct Selection of Conserved cDNAs from the DiGeorge Critical Region: Isolation of a Novel CDC45-Like Gene

Judith M. McKie, Roy B. Wadey, Helen F. Sutherland, Catherine L. Taylor, Peter J. Scambler

Genome Res. 1998 Aug; 8(8): 834–841. doi: 10.1101/gr.8.8.834

PMCID:: PMC310757

Abstract Article PDF–230K

Select item 217179617.

Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation

Mark G. Alexandrow, Joyce L. Hamlin

J Cell Biol. 2005 Mar 14; 168(6): 875–886. doi: 10.1083/jcb.200409055

PMCID:: PMC2171796

Abstract Article PDF–4.0M

Select item 535523818.

Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading

Sissel Hauge, Christian Naucke, Grete Hasvold, Mrinal Joel, Gro Elise Rødland, Petras Juzenas, Trond Stokke, Randi G. Syljuåsen

Oncotarget. 2017 Feb 14; 8(7): 10966–10979. Published online 2016 Dec 22. doi: 10.18632/oncotarget.14089

PMCID:: PMC5355238

Abstract Article PDF–9.8M

Select item 312716019.

Characterization of functional domains in human Claspin

Özdemirhan Serçin, Michael G Kemp

Cell Cycle. 2011 May 15; 10(10): 1599–1606. Published online 2011 May 15. doi: 10.4161/cc.10.10.15562

PMCID:: PMC3127160

Abstract Article PDF–2.4M

Select item 282357520.

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

Adam R. Leman, Chiaki Noguchi, Candice Y. Lee, Eishi Noguchi

J Cell Sci. 2010 Mar 1; 123(5): 660–670. Published online 2010 Feb 2. doi: 10.1242/jcs.057984

PMCID:: PMC2823575

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