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Select item 86052441.

Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma

Anamika Singh, Ariel Erijman, Ashish Noronha, Hemant Kumar, Yoav Peleg, Yosef Yarden, Julia M. Shifman

J Biol Chem. 2021 Dec; 297(6): 101353. Published online 2021 Oct 27. doi: 10.1016/j.jbc.2021.101353

PMCID:: PMC8605244

Abstract Article PDF–2.9M

Select item 33889292.

Expression, purification, crystallization and preliminary X-ray analysis of the human NORE1 SARAH domain

Hye Jin Kim, Eunha Hwang, Young-Hyun Han, Saehae Choi, Woo Cheol Lee, Hye-Yeon Kim, Young Ho Jeon, Chaejoon Cheong, Hae-Kap Cheong

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1; 68(Pt 7): 813–815. Published online 2012 Jun 28. doi: 10.1107/S1744309112021744

PMCID:: PMC3388929

Abstract Article PDF–207K

Select item 29782053.

Epigenetic inactivation of the NORE1 gene correlates with malignant progression of colorectal tumors

Chang Kyun Lee, Jin-Hee Lee, Min-Goo Lee, Seong-In Jeong, Tae-Kyu Ha, Min-Ju Kang, Byung-Kyu Ryu, Young Hwangbo, Jae-Jun Shim, Jae Young Jang, Kil Yeon Lee, Hyo Jong Kim, Sung-Gil Chi

BMC Cancer. 2010; 10: 577. Published online 2010 Oct 22. doi: 10.1186/1471-2407-10-577

PMCID:: PMC2978205

Abstract Article PDF–1.4M

Select item 53973684.

NS5B Promotes Degradation of the NORE1A Tumor Suppressor to Facilitate Hepatitis C Virus Replication

Payal Arora, Amartya Basu, M. Lee Schmidt, Geoffrey J. Clark, Howard Donninger, Daniel B. Nichols, Diego F. Calvisi, Neerja Kaushik-Basu

Hepatology. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Hepatology. 2017 May; 65(5): 1462–1477. Published online 2017 Mar 30. doi: 10.1002/hep.29049

PMCID:: PMC5397368

Abstract Article PDF–2.5M

Select item 47427715.

Ras Regulates Rb via NORE1A

Thibaut Barnoud, Howard Donninger, Geoffrey J. Clark

J Biol Chem. 2016 Feb 5; 291(6): 3114–3123. Published online 2015 Dec 16. doi: 10.1074/jbc.M115.697557

PMCID:: PMC4742771

Abstract Article PDF–1.5M

Select item 42233146.

Ras Regulates SCF^β-TrCP Protein Activity and Specificity via Its Effector Protein NORE1A

M. Lee Schmidt, Howard Donninger, Geoffrey J. Clark

J Biol Chem. 2014 Nov 7; 289(45): 31102–31110. Published online 2014 Sep 12. doi: 10.1074/jbc.M114.594283

PMCID:: PMC4223314

Abstract Article PDF–2.0M

Select item 28714937.

Growth and Tumor Suppressor NORE1A Is a Regulatory Node between Ras Signaling and Microtubule Nucleation

Christine Bee, Anna Moshnikova, Christopher D. Mellor, Justin E. Molloy, Yulia Koryakina, Benjamin Stieglitz, Andrei Khokhlatchev, Christian Herrmann

J Biol Chem. 2010 May 21; 285(21): 16258–16266. Published online 2010 Mar 25. doi: 10.1074/jbc.M109.081562

PMCID:: PMC2871493

Abstract Article PDF–2.2M

Select item 26025968.

The Growth and Tumor Suppressors NORE1A and RASSF1A Are Targets for Calpain-Mediated Proteolysis

Sergey Kuznetsov, Andrei V. Khokhlatchev

PLoS One. 2008; 3(12): e3997. Published online 2008 Dec 22. doi: 10.1371/journal.pone.0003997

PMCID:: PMC2602596

Abstract Article PDF–171K

Select item 14793609.

Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver

Sonia Di Gioia, Paolo Bianchi, Annarita Destro, Fabio Grizzi, Alberto Malesci, Luigi Laghi, Massimo Levrero, Alberto Morabito, Massimo Roncalli

BMC Cancer. 2006; 6: 89. Published online 2006 Apr 10. doi: 10.1186/1471-2407-6-89

PMCID:: PMC1479360

Abstract Article PDF–1.0M

Select item 1109228110.

The Rejuvenation and Functional Restoration of Aged Adipose Stem Cells by DUXAP10 Knockdown via the Regulation of the miR-214-3p/RASSF5 Axis

Sen Ren, Chengcheng Li, Hewei Xiong, Qian Wu, Xiaohui Wu, Zhongwei Xiong, Lixing Dong, Bing Shu, Wei Wei, Chao Ma, Xiang Li, Jincao Chen

Stem Cells Transl Med. 2024 May; 13(5): 462–476. Published online 2024 Mar 9. doi: 10.1093/stcltm/szae015

PMCID:: PMC11092281

Abstract Article PDF–80M

Select item 695725111.

NORE1A Tumor Suppressor Candidate Modulates p21^CIP1 via p53

Diego F. Calvisi, Howard Donninger, Michele D. Vos, Michael J. Birrer, Laura Gordon, Virna Leaner, Geoffrey J. Clark

Cancer Res. Author manuscript; available in PMC 2020 Jan 13.

Published in final edited form as: Cancer Res. 2009 Jun 1; 69(11): 4629–4637. Published online 2009 May 12. doi: 10.1158/0008-5472.CAN-08-3672

PMCID:: PMC6957251

Abstract Article PDF–1.0M

Select item 482395312.

NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism

T Elmetwali, A Salman, D H Palmer

Cell Death Dis. 2016 Mar; 7(3): e2146. Published online 2016 Mar 17. doi: 10.1038/cddis.2016.52

PMCID:: PMC4823953

Abstract Article PDF–2.1M

Select item 361573613.

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner

R Suryaraja, M Anitha, K Anbarasu, G Kumari, S Mahalingam

Cell Death Dis. 2013 Mar; 4(3): e565. Published online 2013 Mar 28. doi: 10.1038/cddis.2013.91

PMCID:: PMC3615736

Abstract Article PDF–1.0M

Select item 349326614.

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

Anna Djos, Tommy Martinsson, Per Kogner, Helena Carén

Mol Cancer. 2012; 11: 40. Published online 2012 Jun 13. doi: 10.1186/1476-4598-11-40

PMCID:: PMC3493266

Abstract Article PDF–1.4M

Select item 320466415.

Nore1B regulates TCR signaling via Ras and Carma1

Kazuhiro Ishiguro, Joe Avruch, Aimee Landry, Shan Qin, Takafumi Ando, Hidemi Goto, Ramnik Xavier

Cell Signal. Author manuscript; available in PMC 2011 Oct 31.

Published in final edited form as: Cell Signal. 2006 Oct; 18(10): 1647–1654. Published online 2006 Mar 7. doi: 10.1016/j.cellsig.2006.01.015

PMCID:: PMC3204664

Abstract Article PDF–1.3M

Select item 436246316.

NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2

Howard Donninger, Diego F. Calvisi, Thibaut Barnoud, Jennifer Clark, M. Lee Schmidt, Michele D. Vos, Geoffrey J. Clark

J Cell Biol. 2015 Mar 16; 208(6): 777–789. doi: 10.1083/jcb.201408087

PMCID:: PMC4362463

Abstract Article PDF–2.4M

Select item 381284717.

T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes

Monika Raab, Hongyan Wang, Yuning Lu, Xin Smith, Zhonglin Wu, Klaus Strebhardt, John E. Ladbury, Christopher E. Rudd

Immunity. Author manuscript; available in PMC 2013 Oct 30.

Published in final edited form as: Immunity. 2010 Apr 23; 32(4): 10.1016/j.immuni.2010.03.007. Published online 2010 Mar 25. doi: 10.1016/j.immuni.2010.03.007