PMC Links for Gene (Select 83961) - PMC

Lingfeng Shi, Yixiang Li, Xiaoli Xu, Yangyang Cheng, Biying Meng, Jinling Xu, Lin Xiang, Jiajia Zhang, Kaiyue He, Jiayue Tong, Junxia Zhang, Lingwei Xiang, Guangda Xiang

Nat Metab. 2022; 4(11): 1573–1590. Published online 2022 Nov 18. doi: 10.1038/s42255-022-00671-0

Correction in:: Nat Metab. 2023; 5(1): 182.

PMCID:: PMC9684073

Abstract Article PDF–22M

Select item 95549734.

Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway

Hongchao Wang, Lijie Wang, Fuli Hu, Pengfei Wang, Yanan Xie, Fang Li, Bingyan Guo

Cardiovasc Diabetol. 2022; 21: 205. Published online 2022 Oct 11. doi: 10.1186/s12933-022-01643-0

PMCID:: PMC9554973

Abstract Article PDF–18M

Select item 86575715.

Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles

Francisco Díaz-Sáez, Carla Blanco-Sinfreu, Adrià Archilla-Ortega, David Sebastian, Montserrat Romero, Maria Isabel Hernández-Alvarez, Sílvia Mora, Xavier Testar, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete, Julián Aragonés, Marta Camps, Antonio Zorzano, Anna Gumà

Int J Mol Sci. 2021 Dec; 22(23): 12960. Published online 2021 Nov 30. doi: 10.3390/ijms222312960

PMCID:: PMC8657571

Abstract Article PDF–5.4M

Select item 81148726.

Neuregulin-4 Is Required for Maintaining Soma Size of Pyramidal Neurons in the Motor Cortex

Blanca Paramo, Sven O. Bachmann, Stéphane J. Baudouin, Isabel Martinez-Garay, Alun M. Davies

eNeuro. 2021 Jan-Feb; 8(1): ENEURO.0288-20.2021. Prepublished online 2021 Jan 25. Published online 2021 Feb 23. doi: 10.1523/ENEURO.0288-20.2021

PMCID:: PMC8114872

Abstract Article PDF–2.7M

Select item 57071587.

Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression

Liang Guo, Peng Zhang, Zhimin Chen, Houjun Xia, Siming Li, Yanqiao Zhang, Sune Kobberup, Weiping Zou, Jiandie D. Lin

J Clin Invest. 2017 Dec 1; 127(12): 4449–4461. Published online 2017 Nov 6. doi: 10.1172/JCI96324

PMCID:: PMC5707158

Abstract Article PDF–13M

Select item 55187218.

Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

Zhimin Chen, Guo-Xiao Wang, Sara L. Ma, Dae Young Jung, Hyekyung Ha, Tariq Altamimi, Xu-Yun Zhao, Liang Guo, Peng Zhang, Chun-Rui Hu, Ji-Xin Cheng, Gary D. Lopaschuk, Jason K. Kim, Jiandie D. Lin

Mol Metab. 2017 Aug; 6(8): 863–872. Published online 2017 Jun 21. doi: 10.1016/j.molmet.2017.03.016

PMCID:: PMC5518721

Abstract Article PDF–1.9M

Select item 48691019.

Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer

Yongjie Ma, Mingming Gao, Dexi Liu

Sci Rep. 2016; 6: 26242. Published online 2016 May 17. doi: 10.1038/srep26242

PMCID:: PMC4869101

Abstract Article PDF–2.0M

Select item 425790710.

The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis

Guo-Xiao Wang, Xu-Yun Zhao, Zhuo-Xian Meng, Matthias Kern, Arne Dietrich, Zhimin Chen, Zoharit Cozacov, Dequan Zhou, Adewole L. Okunade, Xiong Su, Siming Li, Matthias Blüher, Jiandie D. Lin

Nat Med. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Nat Med. 2014 Dec; 20(12): 1436–1443. Published online 2014 Nov 17. doi: 10.1038/nm.3713

PMCID:: PMC4257907

Abstract Article PDF–1.2M

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Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis

Yi Zhang, Yangyang Zhu, Jinghui Wang, Li Jin, Mingwei Guo, Liwei Chen, Lina Zhang, Yangyang Li, Baocheng Wan, Rong Zhang, Weiping Jia, Cheng Hu

Adv Sci (Weinh) 2023 Jun; 10(16): 2204824. Published online 2023 Apr 14. doi: 10.1002/advs.202204824

PMCID:: PMC10238187

Abstract Article PDF–5.5M

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Neuregulin 4 suppresses NASH-HCC development by restraining tumor-prone liver microenvironment

Peng Zhang, Zhimin Chen, Henry Kuang, Tongyu Liu, Jiaqiang Zhu, Linkang Zhou, Qiuyu Wang, Xuelian Xiong, Ziyi Meng, Xiaoxue Qiu, Ramiah Jacks, Lu Liu, Siming Li, Carey N. Lumeng, Qing Li, Xiang Zhou, Jiandie D. Lin

Cell Metab. Author manuscript; available in PMC 2023 Sep 6.

Published in final edited form as: Cell Metab. 2022 Sep 6; 34(9): 1359–1376.e7. Published online 2022 Aug 15. doi: 10.1016/j.cmet.2022.07.010

PMCID:: PMC9458631

Abstract Article PDF–2.9M

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NRG4-ErbB4 signaling represses proinflammatory macrophage activity

Michael A. Schumacher, Isabella C. Dennis, Cambrian Y. Liu, Cache Robinson, Judie Shang, Jessica K. Bernard, M. Kay Washington, D. Brent Polk, Mark R. Frey

Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1; 320(6): G990–G1001. Published online 2021 Apr 7. doi: 10.1152/ajpgi.00296.2020

PMCID:: PMC8285586

Abstract Article

Select item 664091314.

Neuregulin-4 Is Required for the Growth and Elaboration of Striatal Medium Spiny Neuron Dendrites

Blanca Paramo, Sean Wyatt, Alun M Davies

J Neuropathol Exp Neurol. 2019 Aug; 78(8): 725–734. Published online 2019 May 24. doi: 10.1093/jnen/nlz046

PMCID:: PMC6640913

Abstract Article PDF–981K

Select item 586612315.

An essential role for neuregulin-4 in the growth and elaboration of developing neocortical pyramidal dendrites

Blanca Paramo, Sean Wyatt, Alun M. Davies

Exp Neurol. 2018 Apr; 302: 85–92. doi: 10.1016/j.expneurol.2018.01.002

PMCID:: PMC5866123

Abstract Article PDF–1.9M

Select item 350108616.

Neuregulin-4 Is a Survival Factor for Colon Epithelial Cells both in Culture and in Vivo

Jessica K. Bernard, Sean P. McCann, Vrinda Bhardwaj, Mary K. Washington, Mark R. Frey

J Biol Chem. 2012 Nov 16; 287(47): 39850–39858. Published online 2012 Oct 2. doi: 10.1074/jbc.M112.400846

PMCID:: PMC3501086

Abstract Article PDF–1.5M

Select item 313826417.

Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands

Helena Maier, Marion Meixner, Dieter Hartmann, Roger Sandhoff, Lihua Wang-Eckhardt, Inge Zöller, Volkmar Gieselmann, Matthias Eckhardt

J Biol Chem. 2011 Jul 22; 286(29): 25922–25934. Published online 2011 May 31. doi: 10.1074/jbc.M111.231977

PMCID:: PMC3138264

Abstract Article PDF–6.6M

Select item 308956218.

Endothelial Jarid2/Jumonji Is Required for Normal Cardiac Development and Proper Notch1 Expression

Matthew R. Mysliwiec, Emery H. Bresnick, Youngsook Lee

J Biol Chem. 2011 May 13; 286(19): 17193–17204. Published online 2011 Mar 14. doi: 10.1074/jbc.M110.205146

PMCID:: PMC3089562

Abstract Article PDF–3.9M

Select item 674063119.

Identification of a Pax6-Dependent Epidermal Growth Factor Family Signaling Source at the Lateral Edge of the Embryonic Cerebral Cortex

Stavroula Assimacopoulos, Elizabeth A. Grove, Clifton W. Ragsdale

J Neurosci. 2003 Jul 23; 23(16): 6399–6403. doi: 10.1523/JNEUROSCI.23-16-06399.2003

PMCID:: PMC6740631

Abstract Article PDF–447K

Select item 1000669320.

Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain

Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K. Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu, Michael C. Oldham, Alon Greenbaum, H. Troy Ghashghaei

iScience. 2023 Mar 17; 26(3): 106242. Published online 2023 Feb 20. doi: 10.1016/j.isci.2023.106242