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Select item 111592491.

Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4

Akio Takehara, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Tsutomu Kasugai, Masayo Hosokawa, Toyomasa Katagiri, Yusuke Nakamura, Hidewaki Nakagawa

Cancer Sci. 2006 Nov; 97(11): 1191–1197. Published online 2006 Aug 21. doi: 10.1111/j.1349-7006.2006.00297.x

PMCID:: PMC11159249

Abstract Article PDF–290K

Select item 111586112.

Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer

Shinya Ohara, Naohide Oue, Akio Matsubara, Koji Mita, Yasuhisa Hasegawa, Tetsutaro Hayashi, Tsuguru Usui, Vishwa Jeet Amatya, Yukio Takeshima, Hiroki Kuniyasu, Wataru Yasui

Cancer Sci. 2008 Aug; 99(8): 1570–1577. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00846.x

PMCID:: PMC11158611

Abstract Article PDF–600K

Select item 105147553.

Regenerating gene 4 promotes chemoresistance of colorectal cancer by affecting lipid droplet synthesis and assembly

Cong-Yu Zhang, Rui Zhang, Li Zhang, Zi-Mo Wang, Hong-Zhi Sun, Zheng-Guo Cui, Hua-Chuan Zheng

World J Gastroenterol. 2023 Sep 21; 29(35): 5104–5124. Published online 2023 Sep 21. doi: 10.3748/wjg.v29.i35.5104

PMCID:: PMC10514755

Abstract Article PDF–22M

Select item 94439494.

Upregulation of REG IV gene in human intestinal epithelial cells by lipopolysaccharide via downregulation of microRNA‐24

Shin Takasawa, Chikatsugu Tsuchida, Sumiyo Sakuramoto‐Tsuchida, Tomoko Uchiyama, Mai Makino, Akiyo Yamauchi, Asako Itaya‐Hironaka

J Cell Mol Med. 2022 Sep; 26(17): 4710–4720. Published online 2022 Aug 9. doi: 10.1111/jcmm.17498

PMCID:: PMC9443949

Abstract Article PDF–1.1M

Select item 84649935.

Clinicopathological Significance and Prognostic Implications of REG4 Immunohistochemical Expression in Colorectal Cancer

Guhyun Kang, Ilhwan Oh, Jungsoo Pyo, Dongwook Kang, Byoungkwan Son

Medicina (Kaunas) 2021 Sep; 57(9): 938. Published online 2021 Sep 5. doi: 10.3390/medicina57090938

PMCID:: PMC8464993

Abstract Article PDF–1.6M

Select item 64957366.

Reg IV enhances peritoneal metastasis in gastric carcinomas

H. Kuniyasu, N. Oue, T. Sasahira, L. Yi, Y. Moriwaka, T. Shimomoto, K. Fujii, H. Ohmori, W. Yasui

Cell Prolif. 2009 Feb; 42(1): 110–121. Published online 2009 Jan 6. doi: 10.1111/j.1365-2184.2008.00577.x

PMCID:: PMC6495736

Abstract Article PDF–602K

Select item 55497137.

Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway

Jiaoyue Jin, Hang Lv, Junzhou Wu, Dan Li, Kaiyan Chen, Fanrong Zhang, Jing Han, Jianguo Feng, Nan Zhang, Herbert Yu, Dan Su, Lisha Ying

Med Sci Monit. 2017; 23: 3715–3721. Published online 2017 Jul 31. doi: 10.12659/MSM.903134

PMCID:: PMC5549713

Abstract Article PDF–1.1M

Select item 47941658.

REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker

Laura Lehtinen, Pia Vesterkvist, Pia Roering, Taina Korpela, Liisa Hattara, Katja Kaipio, John-Patrick Mpindi, Johanna Hynninen, Annika Auranen, Ben Davidson, Caj Haglund, Kristiina Iljin, Seija Grenman, Harri Siitari, Olli Carpen

PLoS One. 2016; 11(3): e0151590. Published online 2016 Mar 16. doi: 10.1371/journal.pone.0151590

PMCID:: PMC4794165

Abstract Article PDF–905K

Select item 45651429.

Reg4-Induced Mitogenesis Involves Akt-GSK3β-β-Catenin-TCF-4 Signaling in Human Colorectal Cancer

Kumar S Bishnupuri, Satheesh K Sainathan, Kislay Bishnupuri, Devon R Leahy, Qizhi Luo, Shrikant Anant, Courtney W Houchen, Brian K Dieckgraefe

Mol Carcinog. Author manuscript; available in PMC 2015 Sep 10.

Published in final edited form as: Mol Carcinog. 2014 Feb; 53(0 1): E169–E180. Published online 2013 Oct 22. doi: 10.1002/mc.22088

PMCID:: PMC4565142

Abstract Article PDF–1.0M

Select item 446932910.

The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma

Shuo Chen, Wen-Feng Gou, Shuang Zhao, Zhe-Feng Niu, Yang Zhao, Yasuo Takano, Hua-Chuan Zheng

BMC Cancer. 2015; 15: 471. Published online 2015 Jun 16. doi: 10.1186/s12885-015-1435-2

PMCID:: PMC4469329

Abstract Article PDF–4.0M

Select item 419035411.

REG4 Independently Predicts Better Prognosis in Non-Mucinous Colorectal Cancer

Tuomas Kaprio, Jaana Hagström, Harri Mustonen, Selja Koskensalo, Leif C. Andersson, Caj Haglund

PLoS One. 2014; 9(10): e109600. Published online 2014 Oct 8. doi: 10.1371/journal.pone.0109600

PMCID:: PMC4190354

Abstract Article PDF–792K

Select item 346517512.

Oncogenic reg IV is a novel prognostic marker for glioma patient survival

Qi Wang, Jianping Deng, Jun Yuan, Liang Wang, Zhenwei Zhao, Shiming He, Yongsheng Zhang, Yanyang Tu

Diagn Pathol. 2012; 7: 69. Published online 2012 Jun 19. doi: 10.1186/1746-1596-7-69

PMCID:: PMC3465175

Abstract Article PDF–2.6M

Select item 285254213.

RegIV expression showing specificity to gastrointestinal tract and its potential role in diagnosing digestive tract neuroendocrine tumor

Feng-ying Li, Xiao-bin Ren, En-ping Xu, Qiong Huang, Hong-qiang Sheng, Bing-jian Lv, Mao-de Lai

J Zhejiang Univ Sci B. 2010 Apr; 11(4): 258–266. doi: 10.1631/jzus.B0900383

Correction in:: J Zhejiang Univ Sci B. 2010 May; 11(5): 390.

PMCID:: PMC2852542

Abstract Article PDF–557K

Select item 791322814.

CDX2 and Reg IV expression and correlation in gastric cancer

Dandan Chai, Huifen Du, Kesheng Li, Xueliang Zhang, Xiaoqin Li, Xiaoning Zhao, Xiaowen Lian, Yang Xu

BMC Gastroenterol. 2021; 21: 92. Published online 2021 Feb 27. doi: 10.1186/s12876-021-01678-9

PMCID:: PMC7913228

Abstract Article PDF–4.8M

Select item 688536015.

Regulation of REG4 Expression and Prediction of 5-Fluorouracil Sensitivity by CDX2 in Ovarian Mucinous Carcinoma

IEMASA KOH, SUGURU NOSAKA, MASAKI SEKINE, JUN SUGIMOTO, EIJI HIRATA, YOSHIKI KUDO

Cancer Genomics Proteomics. 2019 Nov-Dec; 16(6): 481–490. Published online 2019 Nov 3. doi: 10.21873/cgp.20151

PMCID:: PMC6885360

Abstract Article PDF–595K

Select item 587048916.

Expression of Reg IV and SOX9 and their correlation in human gastric cancer

Na Zhang, Dandan Chai, Huifen Du, Kesheng Li, Wenguang Xie, Xingwen Li, Rong Yang, Xiaowen Lian, Yang Xu

BMC Cancer. 2018; 18: 344. Published online 2018 Mar 27. doi: 10.1186/s12885-018-4285-x

PMCID:: PMC5870489

Abstract Article PDF–3.5M

Select item 505369417.

REG4 promotes peritoneal metastasis of gastric cancer through GPR37

Hexiao Wang, Lei Hu, Mingde Zang, Baogui Zhang, Yantao Duan, Zhiyuan Fan, Jianfang Li, Liping Su, Min Yan, Zhenggang Zhu, Bingya Liu, Qiumeng Yang

Oncotarget. 2016 May 10; 7(19): 27874–27888. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8442

PMCID:: PMC5053694

Abstract Article PDF–5.9M

Select item 404190218.

Tumor suppressor miR-24 restrains gastric cancer progression by downregulating RegIV

Yantao Duan, Lei Hu, Bing Liu, Beiqin Yu, Jianfang Li, Min Yan, Yingyan Yu, Chen Li, Liping Su, Zhenggang Zhu, Ming Xiang, Bingya Liu, Qiumeng Yang

Mol Cancer. 2014; 13: 127. Published online 2014 May 28. doi: 10.1186/1476-4598-13-127

PMCID:: PMC4041902

Abstract Article PDF–1.8M

Select item 383995219.

New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers

TETSUJI SAWADA, MASAKAZU YASHIRO, KAZUHIRO SENTANI, NAOHIDE OUE, WATARU YASUI, KOHJI MIYAZAKI, KEITA KAI, HIDETO FUJITA, KEISHI NAKAMURA, KIYOSHI MAEDA, YOSHIHIRO KAKEJI, SHOJI NATSUGOE, KEN SHIRABE, SACHIYO NOMURA, YUTAKA SHIMADA, NAOHIRO TOMITA, KOSEI HIRAKAWA, YOSHIHIKO MAEHARA

Oncol Rep. 2013 Dec; 30(6): 2609–2616. Published online 2013 Oct 3. doi: 10.3892/or.2013.2787