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Select item 93185921.

Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3

Xiaoyao Yang, Chiara Aloise, Arno L. W. van Vliet, Marleen Zwaagstra, Heyrhyoung Lyoo, Anchun Cheng, Frank J. M. van Kuppeveld

Viruses. 2022 Jul; 14(7): 1360. Published online 2022 Jun 22. doi: 10.3390/v14071360

PMCID:: PMC9318592

Abstract Article PDF–2.3M

Select item 74159852.

Characterization of SETD3 methyltransferase–mediated protein methionine methylation

Shaobo Dai, Matthew V. Holt, John R. Horton, Clayton B. Woodcock, Anamika Patel, Xing Zhang, Nicolas L. Young, Alex W. Wilkinson, Xiaodong Cheng

J Biol Chem. 2020 Aug 7; 295(32): 10901–10910. Published online 2020 Jun 5. doi: 10.1074/jbc.RA120.014072

PMCID:: PMC7415985

Abstract Article PDF–2.1M

Select item 70499553.

An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation

Shaobo Dai, John R. Horton, Alex W. Wilkinson, Or Gozani, Xing Zhang, Xiaodong Cheng

J Biol Chem. 2020 Feb 28; 295(9): 2582–2589. Published online 2020 Jan 7. doi: 10.1074/jbc.RA119.012319

PMCID:: PMC7049955

Abstract Article PDF–2.2M

Select item 70107434.

SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells

Nourhan Hassan, Niklas Rutsch, Balázs Győrffy, Nancy Adriana Espinoza-Sánchez, Martin Götte

Sci Rep. 2020; 10: 2262. Published online 2020 Feb 10. doi: 10.1038/s41598-020-59057-5

PMCID:: PMC7010743

Abstract Article PDF–3.7M

Select item 69710375.

Molecular basis for histidine N3-specific methylation of actin H73 by SETD3

Yihui Zheng, Xingrun Zhang, Haitao Li

Cell Discov. 2020; 6: 3. Published online 2020 Jan 21. doi: 10.1038/s41421-019-0135-5

PMCID:: PMC6971037

Article PDF–3.1M

Select item 66847986.

Structural basis for the target specificity of actin histidine methyltransferase SETD3

Shaobo Dai, John R. Horton, Clayton B. Woodcock, Alex W. Wilkinson, Xing Zhang, Or Gozani, Xiaodong Cheng

Nat Commun. 2019; 10: 3541. Published online 2019 Aug 6. doi: 10.1038/s41467-019-11554-6

PMCID:: PMC6684798

Abstract Article PDF–1.2M

Select item 63476387.

SETD3 is a positive regulator of DNA-damage-induced apoptosis

Elina Abaev-Schneiderman, Lee Admoni-Elisha, Dan Levy

Cell Death Dis. 2019 Feb; 10(2): 74. Published online 2019 Jan 25. doi: 10.1038/s41419-019-1328-4

PMCID:: PMC6347638

Abstract Article PDF–1.7M

Select item 54540898.

Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis

Xiaoqing Cheng, Yuan Hao, Wenjie Shu, Mengjie Zhao, Chen Zhao, Yuan Wu, Xiaodan Peng, Pinfang Yao, Daibiao Xiao, Guoliang Qing, Zhengying Pan, Lei Yin, Desheng Hu, Hai-Ning Du

J Biol Chem. 2017 Jun 2; 292(22): 9022–9033. Published online 2017 Apr 25. doi: 10.1074/jbc.M117.778001

PMCID:: PMC5454089

Abstract Article PDF–2.1M

Select item 110990159.

The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction

Xiaopan Gao, Bei Wang, Kaixiang Zhu, Linyue Wang, Bo Qin, Kun Shang, Wei Ding, Jianwei Wang, Sheng Cui

Nat Commun. 2024; 15: 4176. Published online 2024 May 16. doi: 10.1038/s41467-024-48504-w

PMCID:: PMC11099015

Abstract Article PDF–3.5M

Select item 875257210.

Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression

Tingting Zou, Yang Wang, Ling Dong, Tiantian Che, Huakan Zhao, Xiaohua Yan, Zhenghong Lin

Cell Mol Life Sci. 2022 Jan; 79(1): 70. Published online 2022 Jan 12. doi: 10.1007/s00018-021-04118-9

PMCID:: PMC8752572

Abstract Article PDF–6.8M

Select item 638547411.

CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth

Liangliang Xu, Xinfu Feng, Xiangyong Hao, Peng Wang, Yanfang Zhang, Xiaobo Zheng, Lian Li, Shengsheng Ren, Ming Zhang, Mingqing Xu

J Exp Clin Cancer Res. 2019; 38: 98. Published online 2019 Feb 22. doi: 10.1186/s13046-019-1041-2

PMCID:: PMC6385474

Abstract Article PDF–4.8M

Select item 510925212.

Chromatin associated SETD3 negatively regulates VEGF expression

Ofir Cohn, Michal Feldman, Lital Weil, Margarita Kublanovsky, Dan Levy

Sci Rep. 2016; 6: 37115. Published online 2016 Nov 15. doi: 10.1038/srep37115

PMCID:: PMC5109252

Abstract Article PDF–1.0M

Select item 651126313.

SETD3 is an Actin Histidine Methyltransferase that Prevents Primary Dystocia

Alex W. Wilkinson, Jonathan Diep, Shaobo Dai, Shuo Liu, Yaw shin Ooi, Dan Song, Tie-Mei Li, John R. Horton, Xing Zhang, Chao Liu, Darshan V. Trivedi, Katherine M. Ruppel, José G. Vilches-Moure, Kerriann M. Casey, Justin Mak, Tina Cowan, Joshua E. Elias, Claude M. Nagamine, James A. Spudich, Xiaodong Cheng, Jan E. Carette, Or Gozani

Nature. Author manuscript; available in PMC 2019 Jun 10.

Published in final edited form as: Nature. 2019 Jan; 565(7739): 372–376. Published online 2018 Dec 10. doi: 10.1038/s41586-018-0821-8

PMCID:: PMC6511263

Abstract Article PDF–4.9M

Select item 640049914.

Structural insights into SETD3-mediated histidine methylation on β-actin

Qiong Guo, Shanhui Liao, Sebastian Kwiatkowski, Weronika Tomaka, Huijuan Yu, Gao Wu, Xiaoming Tu, Jinrong Min, Jakub Drozak, Chao Xu

eLife. 2019; 8: e43676. Published online 2019 Feb 20. doi: 10.7554/eLife.43676

PMCID:: PMC6400499

Abstract Article PDF–1.3M

Select item 484421115.

Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication

Ana Sílvia Pires-Luís, Márcia Vieira-Coimbra, Filipa Quintela Vieira, Pedro Costa-Pinheiro, Rui Silva-Santos, Paula C Dias, Luís Antunes, Francisco Lobo, Jorge Oliveira, Céline S Gonçalves, Bruno M Costa, Rui Henrique, Carmen Jerónimo

Epigenetics. 2015 Nov; 10(11): 1033–1043. Published online 2015 Oct 21. doi: 10.1080/15592294.2015.1103578

PMCID:: PMC4844211

Abstract Article PDF–401K

Select item 628957416.

SETD3 protein is the actin-specific histidine N-methyltransferase

Sebastian Kwiatkowski, Agnieszka K Seliga, Didier Vertommen, Marianna Terreri, Takao Ishikawa, Iwona Grabowska, Marcel Tiebe, Aurelio A Teleman, Adam K Jagielski, Maria Veiga-da-Cunha, Jakub Drozak

eLife. 2018; 7: e37921. Published online 2018 Dec 11. doi: 10.7554/eLife.37921

PMCID:: PMC6289574

Abstract Article PDF–7.3M

Select item 318636317.

Histone Methyltransferase SETD3 Regulates Muscle Differentiation

Gwang Hyeon Eom, Kee-Beom Kim, Jin Hee Kim, Ji-Young Kim, Ju-Ryung Kim, Hae Jin Kee, Dong-Wook Kim, Nakwon Choe, Hye-Jeong Park, Hye-Ju Son, Seok-Yong Choi, Hyun Kook, Sang-Beom Seo

J Biol Chem. 2011 Oct 7; 286(40): 34733–34742. Published online 2011 Aug 8. doi: 10.1074/jbc.M110.203307

PMCID:: PMC3186363

Abstract Article PDF–2.2M

Select item 461318818.

A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells

Simon E Cooper, Elsie Hodimont, Catherine M Green

Cell Cycle. 2015 Aug 3; 14(15): 2509–2519. Published online 2015 Jun 1. doi: 10.1080/15384101.2015.1053667

PMCID:: PMC4613188

Abstract Article PDF–681K

Select item 537173019.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 851385320.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

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