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Select item 93569801.

Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

Minjung Kim, Ngoc T. Vu, Xue Wang, Gamze B. Bulut, Min-Hsuan Wang, Cora Uram-Tuculescu, Raghavendra Pillappa, Sungjune Kim, Charles E. Chalfant

Mol Cancer Res. 2022 Aug 5; 20(8): 1284–1294. Published online 2022 Apr 12. doi: 10.1158/1541-7786.MCR-21-0905

PMCID:: PMC9356980

Abstract Article PDF–1.9M

Select item 83866082.

CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis

Hyun-Kyu An, Kyung Min Chung, Hyunhee Park, Jihyun Hong, Ji-Eun Gim, Hyosun Choi, Ye Won Lee, Jieun Choi, Ji Young Mun, Seong-Woon Yu

Autophagy. 2020; 16(9): 1598–1617. Published online 2019 Dec 10. doi: 10.1080/15548627.2019.1695398

PMCID:: PMC8386608

Abstract Article PDF–25M

Select item 80286183.

CASP9 germline mutation in a family with multiple brain tumors

Michael W. Ronellenfitsch, Ji‐Eun Oh, Kaishi Satomi, Koichiro Sumi, Patrick N. Harter, Joachim P. Steinbach, Jörg Felsberg, David Capper, Catherine Voegele, Geoffroy Durand, James McKay, Florence Le Calvez‐Kelm, Jens Schittenhelm, Barbara Klink, Michel Mittelbronn, Hiroko Ohgaki

Brain Pathol. 2018 Jan; 28(1): 94–102. Published online 2017 Apr 17. doi: 10.1111/bpa.12471

PMCID:: PMC8028618

Abstract Article PDF–1.1M

Select item 71777394.

Upregulation of CASP9 through NF-κB and Its Target MiR-1276 Contributed to TNFα-Promoted Apoptosis of Cancer Cells Induced by Doxorubicin

Fei Zhou, Yun Li, Yisheng Huang, Jian Wu, Qinhan Wu, Hui Zhu, Jinke Wang

Int J Mol Sci. 2020 Apr; 21(7): 2290. Published online 2020 Mar 26. doi: 10.3390/ijms21072290

PMCID:: PMC7177739

Abstract Article PDF–5.0M

Select item 71453015.

Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells

Gong-Jhe Wu, Sun-Ta Yang, Ruei-Ming Chen

Molecules. 2020 Mar; 25(6): 1450. Published online 2020 Mar 23. doi: 10.3390/molecules25061450

PMCID:: PMC7145301

Abstract Article PDF–2.8M

Select item 64899646.

Genetic screening and functional analysis of CASP9 mutations in a Chinese cohort with neural tube defects

Xiao‐Zhen Liu, Qin Zhang, Qian Jiang, Bao‐Ling Bai, Xiao‐Juan Du, Fang Wang, Li‐Hua Wu, Xiao‐Lin Lu, Yi‐Hua Bao, Hui‐Li Li, Ting Zhang

CNS Neurosci Ther. 2018 May; 24(5): 394–403. Published online 2018 Jan 24. doi: 10.1111/cns.12797

PMCID:: PMC6489964

Abstract Article PDF–1.3M

Select item 58781467.

CASPASE-9 CARD:CORE DOMAIN INTERACTIONS REQUIRE A PROPERLY-FORMED ACTIVE SITE

Kristen L. Huber, Banyuhay P. Serrano, Jeanne A. Hardy

Biochem J. Author manuscript; available in PMC 2018 Mar 31.

Published in final edited form as: Biochem J. 2018 Mar 29; 475(6): 1177–1196. Published online 2018 Mar 29. doi: 10.1042/BCJ20170913

PMCID:: PMC5878146

Abstract Article PDF–1.1M

Select item 54117468.

Effects of Caspase 9 Gene Polymorphism in Patients with Prostate Cancer

SEDA GULEC YILMAZ, FARUK YENCILEK, ASIF YILDIRIM, ESIN YENCILEK, TURGAY ISBIR

In Vivo. 2017 Mar-Apr; 31(2): 205–208. Published online 2017 Mar 3. doi: 10.21873/invivo.11046

PMCID:: PMC5411746

Abstract Article PDF–1.5M

Select item 51230719.

The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities

Chu-Chiao Wu, Sunhee Lee, Srinivas Malladi, Miao-Der Chen, Nicholas J. Mastrandrea, Zhiwen Zhang, Shawn B. Bratton

Nat Commun. 2016; 7: 13565. Published online 2016 Nov 24. doi: 10.1038/ncomms13565

PMCID:: PMC5123071

Abstract Article PDF–5.2M

Select item 386575910.

Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells

Nicola A. Kearns, Ryan M. J. Genga, Metewo S. Enuameh, Manuel Garber, Scot A. Wolfe, René Maehr

Development. 2014 Jan 1; 141(1): 219–223. doi: 10.1242/dev.103341

PMCID:: PMC3865759

Abstract Article

Select item 366610111.

p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in human lung cells

Victor C. Wong, Jessica L. Morse, Anatoly Zhitkovich

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2014 Jun 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2013 Jun 15; 269(3): 233–239. Published online 2013 Apr 6. doi: 10.1016/j.taap.2013.03.023

PMCID:: PMC3666101

Abstract Article PDF–3.0M

Select item 366353412.

Proteolytic Processing of the Caspase-9 Zymogen Is Required for Apoptosome-mediated Activation of Caspase-9

Qi Hu, Di Wu, Wen Chen, Zhen Yan, Yigong Shi

J Biol Chem. 2013 May 24; 288(21): 15142–15147. Published online 2013 Apr 9. doi: 10.1074/jbc.M112.441568

PMCID:: PMC3663534

Abstract Article PDF–1.2M

Select item 363403713.

Specific Targeting of Caspase-9/PP2A Interaction as Potential New Anti-Cancer Therapy

Issam Arrouss, Fariba Nemati, Fernando Roncal, Marie Wislez, Karim Dorgham, David Vallerand, Nathalie Rabbe, Narjesse Karboul, Françoise Carlotti, Jeronimo Bravo, Dominique Mazier, Didier Decaudin, Angelita Rebollo

PLoS One. 2013; 8(4): e60816. Published online 2013 Apr 23. doi: 10.1371/journal.pone.0060816

PMCID:: PMC3634037

Abstract Article PDF–1.4M

Select item 354417914.

Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface

Kristen Huber, Sumana Ghosh, Jeanne A. Hardy

Biopolymers. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Biopolymers. 2012; 98(5): 451–465. doi: 10.1002/bip.22080

PMCID:: PMC3544179

Abstract Article PDF–4.7M

Select item 351085015.

Systems Analysis of Cancer Cell Heterogeneity in Caspase-dependent Apoptosis Subsequent to Mitochondrial Outer Membrane Permeabilization

Jasmin Schmid, Heiko Dussmann, Gerhardt J. Boukes, Lorna Flanagan, Andreas U. Lindner, Carla L. O'Connor, Markus Rehm, Jochen H. M. Prehn, Heinrich J. Huber

J Biol Chem. 2012 Nov 30; 287(49): 41546–41559. Published online 2012 Oct 4. doi: 10.1074/jbc.M112.411827