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Items: 1 to 20 of 38

1.
Emerging roles of DYRK2 in cancer
Vasudha Tandon, Laureano de la Vega, Sourav Banerjee
J Biol Chem. 2021 Jan-Jun; 296: 100233. Published online 2021 Jan 7. doi: 10.1074/jbc.REV120.015217
PMCID:
PMC7948649
AbstractArticlePDF–1.6M
2.
Dual‐specificity tyrosine‐regulated kinase 2 is a suppressor and potential prognostic marker for liver metastasis of colorectal cancer
Daisuke Ito, Satomi Yogosawa, Rei Mimoto, Shinichi Hirooka, Takashi Horiuchi, Ken Eto, Katsuhiko Yanaga, Kiyotsugu Yoshida
Cancer Sci. 2017 Aug; 108(8): 1565–1573. Published online 2017 Jun 19. doi: 10.1111/cas.13280
PMCID:
PMC5543514
AbstractArticlePDF–970K
3.
Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer
Haiyan Yan, Kaishun Hu, Wenjing Wu, Yu Li, Huan Tian, Zhonghua Chu, H. Phillip Koeffler, Dong Yin
PLoS One. 2016; 11(8): e0159954. Published online 2016 Aug 17. doi: 10.1371/journal.pone.0159954
PMCID:
PMC4988784
AbstractArticlePDF–6.2M
4.
FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
Rafael Jiménez-Izquierdo, Rosario Morrugares, Lucía Suanes-Cobos, Alejandro Correa-Sáez, Martín Garrido-Rodríguez, Laura Cerero-Tejero, Omar M. Khan, Susana de la Luna, Rocío Sancho, Marco A. Calzado
Cell Death Dis. 2023 Mar; 14(3): 202. Published online 2023 Mar 18. doi: 10.1038/s41419-023-05724-0
PMCID:
PMC10024693
AbstractArticlePDF–5.4M
5.
Dual inhibition of HSF1 and DYRK2 impedes cancer progression
Vasudha Tandon, Rita Moreno, Kira Allmeroth, Jean Quinn, Sandra E. Wiley, Lynden G. Nicely, Martin S. Denzel, Joanne Edwards, Laureano de la Vega, Sourav Banerjee
Biosci Rep. 2023 Jan 31; 43(1): BSR20222102. Published online 2023 Jan 30. doi: 10.1042/BSR20222102
PMCID:
PMC9894012
AbstractArticlePDF–3.5M
6.
Downregulation of dual‐specificity tyrosine‐regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin‐dependent kinase 14 expression in breast cancer
Yoshimi Imawari, Rei Mimoto, Shinichi Hirooka, Toshiaki Morikawa, Hiroshi Takeyama, Kiyotsugu Yoshida
Cancer Sci. 2018 Feb; 109(2): 363–372. Published online 2018 Jan 13. doi: 10.1111/cas.13459
PMCID:
PMC5797831
AbstractArticlePDF–1.0M
7.
Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
Tiantian Wei, Jue Wang, Ruqi Liang, Wendong Chen, Yilan Chen, Mingzhe Ma, An He, Yifei Du, Wenjing Zhou, Zhiying Zhang, Xin Zeng, Chu Wang, Jin Lu, Xing Guo, Xiao-Wei Chen, Youjun Wang, Ruijun Tian, Junyu Xiao, Xiaoguang Lei
eLife. 2022; 11: e77696. Published online 2022 Apr 19. doi: 10.7554/eLife.77696
PMCID:
PMC9113749
AbstractArticlePDF–7.6M
8.
DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor
N Max Schabla, Koushik Mondal, Patrick C Swanson
J Mol Cell Biol. 2019 Sep; 11(9): 725–735. Published online 2018 Dec 24. doi: 10.1093/jmcb/mjy085
PMCID:
PMC6821201
AbstractArticlePDF–1.0M
9.
DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation
Tai An, Shu Li, Wei Pan, Po Tien, Bo Zhong, Hong-Bing Shu, Shuwen Wu
PLoS Pathog. 2015 Sep; 11(9): e1005179. Published online 2015 Sep 25. doi: 10.1371/journal.ppat.1005179
PMCID:
PMC4583546
AbstractArticlePDF–2.5M
10.
Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin
K Matsuura, N-J Huang, K Cocce, L Zhang, S Kornbluth
Oncogene. 2017 Mar 23; 36(12): 1698–1706. Published online 2016 Oct 10. doi: 10.1038/onc.2016.336
PMCID:
PMC5447866
AbstractArticlePDF–2.0M
11.
Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2
Su Sien Ong, Asli N. Goktug, Ayesha Elias, Jing Wu, Darren Saunders, Taosheng Chen
Biochem J. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Biochem J. 2014 Apr 1; 459(1): 193–203. doi: 10.1042/BJ20130558
PMCID:
PMC3959618
AbstractArticlePDF–3.3M
12.
Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
Youngsik Woo, Soo Jeong Kim, Bo Kyoung Suh, Yongdo Kwak, Hyun-Jin Jung, Truong Thi My Nhung, Dong Jin Mun, Ji-Ho Hong, Su-Jin Noh, Seunghyun Kim, Ahryoung Lee, Seung Tae Baek, Minh Dang Nguyen, Youngshik Choe, Sang Ki Park
eLife. 2019; 8: e50850. Published online 2019 Dec 9. doi: 10.7554/eLife.50850
PMCID:
PMC6927744
AbstractArticlePDF–4.8M
13.
Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation
Hae-Yun Jung, Xin Wang, Sohee Jun, Jae-Il Park
J Biol Chem. 2013 Mar 8; 288(10): 7252–7262. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.416792
PMCID:
PMC3591633
AbstractArticlePDF–2.6M
14.
DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells
Naoe Taira, Rei Mimoto, Morito Kurata, Tomoko Yamaguchi, Masanobu Kitagawa, Yoshio Miki, Kiyotsugu Yoshida
J Clin Invest. 2012 Mar 1; 122(3): 859–872. Published online 2012 Feb 6. doi: 10.1172/JCI60818
PMCID:
PMC3287383
AbstractArticlePDF–2.3M
15.
ATM Augments Nuclear Stabilization of DYRK2 by Inhibiting MDM2 in the Apoptotic Response to DNA Damage
Naoe Taira, Hiroyuki Yamamoto, Tomoko Yamaguchi, Yoshio Miki, Kiyotsugu Yoshida
J Biol Chem. 2010 Feb 12; 285(7): 4909–4919. Published online 2009 Dec 4. doi: 10.1074/jbc.M109.042341
PMCID:
PMC2836095
AbstractArticlePDF–2.5M
16.
The C Terminus of Initiation Factor 4E-Binding Protein 1 Contains Multiple Regulatory Features That Influence Its Function and Phosphorylation
Xuemin Wang, Wei Li, Josep-Lluis Parra, Anne Beugnet, Christopher G. Proud
Mol Cell Biol. 2003 Mar; 23(5): 1546–1557. doi: 10.1128/MCB.23.5.1546-1557.2003
PMCID:
PMC151707
AbstractArticlePDF–374K
17.
Cep78 controls centrosome homeostasis by inhibiting EDD‐DYRK2‐DDB1VprBP
Delowar Hossain, Yalda Javadi Esfehani, Arindam Das, William Y Tsang
EMBO Rep. 2017 Apr; 18(4): 632–644. Published online 2017 Feb 27. doi: 10.15252/embr.201642377
PMCID:
PMC5376967
AbstractArticlePDF–2.8M
18.
HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis
Delowar Hossain, Jérémy A. Ferreira Barbosa, Éric A. Cohen, William Y. Tsang
J Biol Chem. 2018 Jun 15; 293(24): 9448–9460. Published online 2018 May 3. doi: 10.1074/jbc.RA117.001444
PMCID:
PMC6005440
AbstractArticlePDF–2.8M
19.
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.
Y L Woods, P Cohen, W Becker, R Jakes, M Goedert, X Wang, C G Proud
Biochem J. 2001 May 1; 355(Pt 3): 609–615. doi: 10.1042/bj3550609
PMCID:
PMC1221774
SummaryPDF–191K
20.
CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression
Varun Jayeshkumar Shah, Subbareddy Maddika
J Cell Sci. 2018 Apr 15; 131(8): jcs213868. Published online 2018 Apr 26. doi: 10.1242/jcs.213868
PMCID:
PMC5963846
AbstractArticle

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