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Select item 111312531.

CircPIAS1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis via the miR-455-3p/NUPR1/FTH1 axis

Xiao-Yu Zhang, Shan-Shan Li, Yu-Rong Gu, Le-Xin Xiao, Xin-Yi Ma, Xin-Ru Chen, Jia-Liang Wang, Chun-Hong Liao, Bing-Liang Lin, Yue-Hua Huang, Yi-Fan Lian

Mol Cancer. 2024; 23: 113. Published online 2024 May 28. doi: 10.1186/s12943-024-02030-x

PMCID:: PMC11131253

Abstract Article PDF–16M

Select item 111158252.

PIAS proteins: pleiotropic interactors associated with SUMO

Miia M. Rytinki, Sanna Kaikkonen, Petri Pehkonen, Tiina Jääskeläinen, Jorma J. Palvimo

Cell Mol Life Sci. 2009 Sep; 66(18): 3029–3041. Published online 2009 Jun 13. doi: 10.1007/s00018-009-0061-z

PMCID:: PMC11115825

Abstract Article PDF–475K

Select item 80349053.

Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing

Kan He, Jian Zhang, Justin Liu, Yandi Cui, Leyna G. Liu, Shoudong Ye, Qian Ban, Ruolan Pan, Dahai Liu

Aging (Albany NY) 2021 Mar 31; 13(6): 9011–9027. Published online 2021 Mar 24. doi: 10.18632/aging.202749

PMCID:: PMC8034905

Abstract Article PDF–1.3M

Select item 70128864.

Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility

Chongyang Li, Francis P. McManus, Cédric Plutoni, Cristina Mirela Pascariu, Trent Nelson, Lara Elis Alberici Delsin, Gregory Emery, Pierre Thibault

Nat Commun. 2020; 11: 834. Published online 2020 Feb 11. doi: 10.1038/s41467-020-14581-w

PMCID:: PMC7012886

Abstract Article PDF–2.4M

Select item 57410985.

B Cell Receptor Activation and Chemical Induction Trigger Caspase-Mediated Cleavage of PIAS1 to Facilitate Epstein-Barr Virus Reactivation

Kun Zhang, Dong-Wen Lv, Renfeng Li

Cell Rep. Author manuscript; available in PMC 2017 Dec 22.

Published in final edited form as: Cell Rep. 2017 Dec 19; 21(12): 3445–3457. doi: 10.1016/j.celrep.2017.11.071

PMCID:: PMC5741098

Abstract Article PDF–1.7M

Select item 54267746.

Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer

Ayan Chanda, Angela Chan, Lili Deng, Elizabeth N. Kornaga, Emeka K. Enwere, Donald G. Morris, Shirin Bonni

PLoS One. 2017; 12(5): e0177639. Published online 2017 May 11. doi: 10.1371/journal.pone.0177639

PMCID:: PMC5426774

Abstract Article PDF–7.9M

Select item 49072227.

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1

James R. Brown, Kristen L. Conn, Peter Wasson, Matthew Charman, Lily Tong, Kyle Grant, Steven McFarlane, Chris Boutell

J Virol. 2016 Jul 1; 90(13): 5939–5952. Prepublished online 2016 Apr 20. Published online 2016 Jun 10. doi: 10.1128/JVI.00426-16

PMCID:: PMC4907222

Abstract Article PDF–5.3M

Select item 43229988.

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg Schäfer, Stephan Geley, Isabel Heidegger, Helmut Klocker, Zoran Culig

Oncotarget. 2014 Dec; 5(23): 12043–12056. Published online 2014 Dec 24. doi: 10.18632/oncotarget.2658

PMCID:: PMC4322998

Abstract Article PDF–2.2M

Select item 39335659.

PIAS1 Regulates Breast Tumorigenesis through Selective Epigenetic Gene Silencing

Bin Liu, Samuel Tahk, Kathleen M. Yee, Randy Yang, Yonghui Yang, Ryan Mackie, Cary Hsu, Vasili Chernishof, Neil O'Brien, Yusheng Jin, Guoping Fan, Timothy F. Lane, Jianyu Rao, Dennis Slamon, Ke Shuai

PLoS One. 2014; 9(2): e89464. Published online 2014 Feb 24. doi: 10.1371/journal.pone.0089464

PMCID:: PMC3933565

Abstract Article PDF–1.7M

Select item 317757210.

The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death

Beatriz B. Leitao, Marius C. Jones, Jan J. Brosens

FASEB J. 2011 Oct; 25(10): 3416–3425. doi: 10.1096/fj.11-186346

PMCID:: PMC3177572

Abstract Article

Select item 1079484711.

Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation

Patric J. Ho, Junghun Kweon, Laura A. Blumensaadt, Amy E. Neely, Elizabeth Kalika, Daniel B. Leon, Sanghyon Oh, Cooper W.P. Stringer, Sarah M. Lloyd, Ziyou Ren, Xiaomin Bao

Cell Genom. 2024 Jan 10; 4(1): 100471. Published online 2024 Jan 2. doi: 10.1016/j.xgen.2023.100471

PMCID:: PMC10794847

Abstract Article PDF–7.2M

Select item 741560612.

Novel variants of ELP2 and PIAS1 in the interferon gamma signaling pathway are associated with non-small cell lung cancer survival

Yu Chen Zhao, Dongfang Tang, Sen Yang, Hongliang Liu, Sheng Luo, Thomas E. Stinchcombe, Carolyn Glass, Li Su, Sipeng Shen, David C. Christiani, Qingyi Wei

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 Aug; 29(8): 1679–1688. Published online 2020 Jun 3. doi: 10.1158/1055-9965.EPI-19-1450

PMCID:: PMC7415606

Abstract Article PDF–1.0M

Select item 730719513.

Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites

Claire Guérillon, Stine Smedegaard, Ivo A. Hendriks, Michael L. Nielsen, Niels Mailand

J Biol Chem. 2020 Jun 19; 295(25): 8350–8362. Published online 2020 Apr 29. doi: 10.1074/jbc.RA120.013780

PMCID:: PMC7307195

Abstract Article PDF–3.3M

Select item 494230614.

PIAS1 regulates mutant Huntingtin accumulation and Huntington’s disease-associated phenotypes in vivo

Joseph Ochaba, Alex Mas Monteys, Jacqueline G. O’Rourke, Jack C. Reidling, Joan S. Steffan, Beverly L. Davidson, Leslie M. Thompson

Neuron. Author manuscript; available in PMC 2017 May 4.

Published in final edited form as: Neuron. 2016 May 4; 90(3): 507–520. Published online 2016 Apr 14. doi: 10.1016/j.neuron.2016.03.016

PMCID:: PMC4942306

Abstract Article PDF–1.7M

Select item 486547615.

PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer

M Puhr, J Hoefer, A Eigentler, D Dietrich, G van Leenders, B Uhl, M Hoogland, F Handle, B Schlick, H Neuwirt, V Sailer, G Kristiansen, H Klocker, Z Culig

Oncogene. 2016 May 5; 35(18): 2322–2332. Published online 2015 Aug 10. doi: 10.1038/onc.2015.292

PMCID:: PMC4865476

Abstract Article PDF–4.3M

Select item 410631816.

High Mobility Group Nucleosomal Binding Domain 2 (HMGN2) SUMOylation by the SUMO E3 Ligase PIAS1 Decreases the Binding Affinity to Nucleosome Core Particles

Jie Wu, Sol Kim, Man Sup Kwak, Jang Bin Jeong, Hyun Jin Min, Ho-Geun Yoon, Jin-Hyun Ahn, Jeon-Soo Shin

J Biol Chem. 2014 Jul 18; 289(29): 20000–20011. Published online 2014 May 28. doi: 10.1074/jbc.M114.555425

PMCID:: PMC4106318

Abstract Article PDF–3.0M

Select item 386874617.

Identification of a Non-covalent Ternary Complex Formed by PIAS1, SUMO1, and UBC9 Proteins Involved in Transcriptional Regulation

Xavier H. Mascle, Mathieu Lussier-Price, Laurent Cappadocia, Patricia Estephan, Luca Raiola, James G. Omichinski, Muriel Aubry

J Biol Chem. 2013 Dec 20; 288(51): 36312–36327. Published online 2013 Oct 30. doi: 10.1074/jbc.M113.486845

PMCID:: PMC3868746

Abstract Article PDF–2.1M

Select item 357571218.

The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci

Raghavi Sudharsan, Yoshiaki Azuma

J Cell Sci. 2012 Dec 1; 125(23): 5819–5829. doi: 10.1242/jcs.110825

PMCID:: PMC3575712

Abstract Article

Select item 333449719.

PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation

Narasimhaswamy S. Belaguli, Mao Zhang, Andres-Hernandez Garcia, David H. Berger

PLoS One. 2012; 7(4): e35717. Published online 2012 Apr 23. doi: 10.1371/journal.pone.0035717

Correction in:: PLoS One. 2012; 7(9): 10.1371/annotation/e56fbda3-1898-4a36-bf93-d33d5a8b2d2e.

PMCID:: PMC3334497

Abstract Article PDF–1022K

Select item 285442920.

The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome

James J. Driscoll, Dheeraj Pelluru, Konstantinos Lefkimmiatis, Mariateresa Fulciniti, Rao H. Prabhala, Philip R. Greipp, Bart Barlogie, Yu-Tzu Tai, Kenneth C. Anderson, John D. Shaughnessy, Jr, Christina M. Annunziata, Nikhil C. Munshi

Blood. 2010 Apr 8; 115(14): 2827–2834. Prepublished online 2009 Nov 30. doi: 10.1182/blood-2009-03-211045