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Items: 1 to 20 of 84

1.
Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.
Nilce N Hashimoto, Larissa S Carnevalli, Beatriz A Castilho
Biochem J. 2002 Oct 15; 367(Pt 2): 359–368. doi: 10.1042/BJ20020556
PMCID:
PMC1222906
SummaryPDF–373K
2.
Large-scale movement of eIF3 domains during translation initiation modulate start codon selection
Jose L Llácer, Tanweer Hussain, Jinsheng Dong, Laura Villamayor, Yuliya Gordiyenko, Alan G Hinnebusch
Nucleic Acids Res. 2021 Nov 18; 49(20): 11491–11511. Published online 2021 Oct 14. doi: 10.1093/nar/gkab908
PMCID:
PMC8599844
AbstractArticlePDF–6.6M
3.
Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes
Martin D Jennings, Christopher J Kershaw, Tomas Adomavicius, Graham D Pavitt
eLife. 2017; 6: e24542. Published online 2017 Mar 18. doi: 10.7554/eLife.24542
PMCID:
PMC5404910
AbstractArticlePDF–1.4M
4.
Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control
Klaus H Nielsen, Béla Szamecz, Leoš Valášek, Antonina Jivotovskaya, Byung-Sik Shin, Alan G Hinnebusch
EMBO J. 2004 Mar 10; 23(5): 1166–1177. Published online 2004 Feb 19. doi: 10.1038/sj.emboj.7600116
PMCID:
PMC380973
AbstractArticlePDF–540K
5.
Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron.
C M Grant, P F Miller, A G Hinnebusch
Mol Cell Biol. 1994 Apr; 14(4): 2616–2628. doi: 10.1128/mcb.14.4.2616
PMCID:
PMC358629
SummaryPage BrowsePDF–2.7M
6.
The β Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C2-C2 Motif
Jomar P. Laurino, Glória M. Thompson, Eliza Pacheco, Beatriz A. Castilho
Mol Cell Biol. 1999 Jan; 19(1): 173–181. doi: 10.1128/mcb.19.1.173
Correction in:
Mol Cell Biol. 1999 Apr; 19(4): 3224.
PMCID:
PMC83876
AbstractArticlePDF–1021K
7.
eIF2β zinc-binding domain interacts with the eIF2γ subunit through the guanine nucleotide binding interface to promote Met-tRNAiMet binding
Aranyadip Gayen, Pankaj V. Alone
Biosci Rep. 2024 Jul 31; 44(7): BSR20240438. Published online 2024 Jul 5. doi: 10.1042/BSR20240438
PMCID:
PMC11230868
AbstractArticlePDF–8.7M
8.
A network of eIF2β interactions with eIF1 and Met-tRNAi promotes accurate start codon selection by the translation preinitiation complex
Anil Thakur, Laura Marler, Alan G Hinnebusch
Nucleic Acids Res. 2019 Mar 18; 47(5): 2574–2593. Published online 2018 Dec 21. doi: 10.1093/nar/gky1274
PMCID:
PMC6411837
AbstractArticlePDF–5.9M
9.
The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo
Jyothsna Visweswaraiah, Yvette Pittman, Thomas E Dever, Alan G Hinnebusch
eLife. 2015; 4: e07939. Published online 2015 Jul 2. doi: 10.7554/eLife.07939
PMCID:
PMC4513230
AbstractArticlePDF–3.5M
10.
Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA
Marie Naveau, Christine Lazennec-Schurdevin, Michel Panvert, Etienne Dubiez, Yves Mechulam, Emmanuelle Schmitt
Nucleic Acids Res. 2013 Jan; 41(2): 1047–1057. Published online 2012 Nov 26. doi: 10.1093/nar/gks1180
PMCID:
PMC3553985
AbstractArticlePDF–5.2M
11.
Functional Elements in Initiation Factors 1, 1A, and 2β Discriminate against Poor AUG Context and Non-AUG Start Codons
Pilar Martin-Marcos, Yuen-Nei Cheung, Alan G. Hinnebusch
Mol Cell Biol. 2011 Dec; 31(23): 4814–4831. doi: 10.1128/MCB.05819-11
PMCID:
PMC3232919
AbstractArticlePDF–3.5M
12.
Translation Initiation Factor 2γ Mutant Alters Start Codon Selection Independent of Met-tRNA Binding
Pankaj V. Alone, Chune Cao, Thomas E. Dever
Mol Cell Biol. 2008 Nov; 28(22): 6877–6888. Published online 2008 Sep 15. doi: 10.1128/MCB.01147-08
PMCID:
PMC2573310
AbstractArticlePDF–1.2M
13.
N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection
Christie A Fekete, Sarah F Mitchell, Vera A Cherkasova, Drew Applefield, Mikkel A Algire, David Maag, Adesh K Saini, Jon R Lorsch, Alan G Hinnebusch
EMBO J. 2007 Mar 21; 26(6): 1602–1614. Published online 2007 Mar 1. doi: 10.1038/sj.emboj.7601613
PMCID:
PMC1829380
AbstractArticlePDF–391K
14.
Eukaryotic Translation Initiation Factor 3 (eIF3) and eIF2 Can Promote mRNA Binding to 40S Subunits Independently of eIF4G in Yeast
Antonina V. Jivotovskaya, Leoš Valášek, Alan G. Hinnebusch, Klaus H. Nielsen
Mol Cell Biol. 2006 Feb; 26(4): 1355–1372. doi: 10.1128/MCB.26.4.1355-1372.2006
PMCID:
PMC1367198
AbstractArticlePDF–1.3M
15.
Conserved sequences in the beta subunit of archaeal and eukaryal translation initiation factor 2 (eIF2), absent from eIF5, mediate interaction with eIF2gamma.
G M Thompson, E Pacheco, E O Melo, B A Castilho
Biochem J. 2000 May 1; 347(Pt 3): 703–709.
PMCID:
PMC1221006
SummaryPDF–205K
16.
Genetic Characterization of the Saccharomyces Cerevisiae Translational Initiation Suppressors Sui1, Sui2 and Sui3 and Their Effects on His4 Expression
B. Castilho-Valavicius, H. Yoon, T. F. Donahue
Genetics. 1990 Mar; 124(3): 483–495. doi: 10.1093/genetics/124.3.483
PMCID:
PMC1203942
SummaryPDF–2.9M
17.
GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
Han-kuei Huang, Heejeong Yoon, Ernest M. Hannig, Thomas F. Donahue
Genes Dev. 1997 Sep 15; 11(18): 2396–2413. doi: 10.1101/gad.11.18.2396
PMCID:
PMC316512
AbstractArticlePDF–932K
18.
Eukaryotic Translation Initiation Factor 5 Is Critical for Integrity of the Scanning Preinitiation Complex and Accurate Control of GCN4 Translation
Chingakham Ranjit Singh, Cynthia Curtis, Yasufumi Yamamoto, Nathan S. Hall, Dustin S. Kruse, Hui He, Ernest M. Hannig, Katsura Asano
Mol Cell Biol. 2005 Jul; 25(13): 5480–5491. doi: 10.1128/MCB.25.13.5480-5491.2005
PMCID:
PMC1156968
AbstractArticlePDF–818K
19.
Interactions of Eukaryotic Translation Initiation Factor 3 (eIF3) Subunit NIP1/c with eIF1 and eIF5 Promote Preinitiation Complex Assembly and Regulate Start Codon Selection
Leoš Valášek, Klaus H. Nielsen, Fan Zhang, Christie A. Fekete, Alan G. Hinnebusch
Mol Cell Biol. 2004 Nov; 24(21): 9437–9455. doi: 10.1128/MCB.24.21.9437-9455.2004
PMCID:
PMC522265
AbstractArticlePDF–1.2M
20.
Mutations in the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) that overcome the inhibitory effect of eIF-2 alpha phosphorylation on translation initiation.
C R Vazquez de Aldana, T E Dever, A G Hinnebusch
Proc Natl Acad Sci U S A. 1993 Aug 1; 90(15): 7215–7219. doi: 10.1073/pnas.90.15.7215
PMCID:
PMC47107
SummaryPage BrowsePDF–1.4M

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