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Select item 50371611.

Loss of ncm⁵ and mcm⁵ wobble uridine side chains results in an altered metabolic profile

Tony Karlsborn, A. K. M. Firoj Mahmud, Hasan Tükenmez, Anders S. Byström

Metabolomics. 2016; 12(12): 177. Published online 2016 Sep 27. doi: 10.1007/s11306-016-1120-8

PMCID:: PMC5037161

Abstract Article PDF–1.9M

Select item 70722212.

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast

Leticia Pollo-Oliveira, Roland Klassen, Nick Davis, Akif Ciftci, Jo Marie Bacusmo, Maria Martinelli, Michael S. DeMott, Thomas J. Begley, Peter C. Dedon, Raffael Schaffrath, Valérie de Crécy-Lagard

Biomolecules. 2020 Feb; 10(2): 322. Published online 2020 Feb 18. doi: 10.3390/biom10020322

PMCID:: PMC7072221

Abstract Article PDF–7.5M

Select item 30305693.

Comparative Studies of Genome-Wide Maps of Nucleosomes between Deletion Mutants of elp3 and hos2 Genes of Saccharomyces cerevisiae

Takashi Matsumoto, Choong-Soo Yun, Hirofumi Yoshikawa, Hiromi Nishida

PLoS One. 2011; 6(1): e16372. Published online 2011 Jan 28. doi: 10.1371/journal.pone.0016372

PMCID:: PMC3030569

Abstract Article PDF–247K

Select item 66200984.

Molecular basis of tRNA recognition by the Elongator complex

Maria I. Dauden, Marcin Jaciuk, Felix Weis, Ting-Yu Lin, Carolin Kleindienst, Nour El Hana Abbassi, Heena Khatter, Rościsław Krutyhołowa, Karin D. Breunig, Jan Kosinski, Christoph W. Müller, Sebastian Glatt

Sci Adv. 2019 Jul; 5(7): eaaw2326. Published online 2019 Jul 10. doi: 10.1126/sciadv.aaw2326

PMCID:: PMC6620098

Abstract Article PDF–2.0M

Select item 46270755.

The role of wobble uridine modifications in +1 translational frameshifting in eukaryotes

Hasan Tükenmez, Hao Xu, Anders Esberg, Anders S. Byström

Nucleic Acids Res. 2015 Oct 30; 43(19): 9489–9499. Published online 2015 Aug 17. doi: 10.1093/nar/gkv832

PMCID:: PMC4627075

Abstract Article PDF–2.4M

Select item 29044996.

Elongator function in tRNA wobble uridine modification is conserved between yeast and plants

Constance Mehlgarten, Daniel Jablonowski, Uta Wrackmeyer, Susan Tschitschmann, David Sondermann, Gunilla Jäger, Zhizhong Gong, Anders S Byström, Raffael Schaffrath, Karin D Breunig

Mol Microbiol. 2010 Jun; 76(5): 1082–1094. Published online 2010 Apr 26. doi: 10.1111/j.1365-2958.2010.07163.x

PMCID:: PMC2904499

Abstract Article PDF–788K

Select item 83960227.

Role of SSD1 in Phenotypic Variation of Saccharomyces cerevisiae Strains Lacking DEG1-Dependent Pseudouridylation

Bahar Khonsari, Roland Klassen, Raffael Schaffrath

Int J Mol Sci. 2021 Aug; 22(16): 8753. Published online 2021 Aug 15. doi: 10.3390/ijms22168753

PMCID:: PMC8396022

Abstract Article PDF–2.9M

Select item 79712658.

tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast

Joana F Tavares, Nick K. Davis, Ana Poim, Andreia Reis, Stefanie Kellner, Inês Sousa, Ana R. Soares, Gabriela M R Moura, Peter C Dedon, Manuel Santos

RNA Biol. 2021; 18(4): 563–575. Published online 2020 Sep 17. doi: 10.1080/15476286.2020.1819671

PMCID:: PMC7971265

Abstract Article PDF–5.8M

Select item 41505329.

A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex

Rachael Di Santo, Susanne Bandau, Michael J R Stark

Mol Microbiol. 2014 Jun; 92(6): 1227–1242. Published online 2014 May 19. doi: 10.1111/mmi.12624

PMCID:: PMC4150532

Abstract Article PDF–17M

Select item 141328510.

The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4

Michael-Christopher Keogh, Thomas A. Mennella, Chika Sawa, Sharon Berthelet, Nevan J. Krogan, Adam Wolek, Vladimir Podolny, Laura Rocco Carpenter, Jack F. Greenblatt, Kristin Baetz, Stephen Buratowski

Genes Dev. 2006 Mar 15; 20(6): 660–665. doi: 10.1101/gad.1388106

PMCID:: PMC1413285

Abstract Article PDF–458K

Select item 627507311.

Unfolded Protein Response Suppression in Yeast by Loss of tRNA Modifications

Alexander Bruch, Roland Klassen, Raffael Schaffrath

Genes (Basel) 2018 Nov; 9(11): 516. Published online 2018 Oct 23. doi: 10.3390/genes9110516

PMCID:: PMC6275073

Abstract Article PDF–1.3M

Select item 586655812.

Deciphering the reading of the genetic code by near-cognate tRNA

Sandra Blanchet, David Cornu, Isabelle Hatin, Henri Grosjean, Pierre Bertin, Olivier Namy

Proc Natl Acad Sci U S A. 2018 Mar 20; 115(12): 3018–3023. Published online 2018 Mar 5. doi: 10.1073/pnas.1715578115

PMCID:: PMC5866558

Abstract Article PDF–914K

Select item 471748813.

Global translational impacts of the loss of the tRNA modification t⁶A in yeast

Patrick C. Thiaville, Rachel Legendre, Diego Rojas-Benítez, Agnès Baudin-Baillieu, Isabelle Hatin, Guilhem Chalancon, Alvaro Glavic, Olivier Namy, Valérie de Crécy-Lagard

Microb Cell. 2016 Jan 4; 3(1): 29–45. Published online 2015 Dec 18. doi: 10.15698/mic2016.01.473

PMCID:: PMC4717488

Abstract Article PDF–2.4M

Select item 736718814.

Misactivation of multiple starvation responses in yeast by loss of tRNA modifications

Alexander Bruch, Teresa Laguna, Falk Butter, Raffael Schaffrath, Roland Klassen

Nucleic Acids Res. 2020 Jul 27; 48(13): 7307–7320. Published online 2020 Jun 2. doi: 10.1093/nar/gkaa455

PMCID:: PMC7367188

Abstract Article PDF–3.8M

Select item 528639415.

Architecture of the yeast Elongator complex

Maria I Dauden, Jan Kosinski, Olga Kolaj‐Robin, Ambroise Desfosses, Alessandro Ori, Celine Faux, Niklas A Hoffmann, Osita F Onuma, Karin D Breunig, Martin Beck, Carsten Sachse, Bertrand Séraphin, Sebastian Glatt, Christoph W Müller

EMBO Rep. 2017 Feb; 18(2): 264–279. Published online 2016 Dec 14. doi: 10.15252/embr.201643353