PMC Links for Gene (Select 856746) - PMC

Louise C. Gregory, Carolina B. Ferreira, Sara K. Young-Baird, Hywel J. Williams, Magdalena Harakalova, Gijs van Haaften, Sofia A. Rahman, Carles Gaston-Massuet, Daniel Kelberman, GOSgene, Waseem Qasim, Sally A. Camper, Thomas E. Dever, Pratik Shah, Iain C.A.F. Robinson, Mehul T. Dattani

EBioMedicine. 2019 Apr; 42: 470–480. Published online 2019 Mar 14. doi: 10.1016/j.ebiom.2019.03.013

PMCID:: PMC6492072

Abstract Article PDF–1.8M

Select item 62677864.

EIF2S3 mutations associated with severe X-linked intellectual disability syndrome MEHMO

Martina Skopkova, Friederike Hennig, Byung-Sik Shin, Clesson E. Turner, Daniela Stanikova, Katarina Brennerova, Juraj Stanik, Ute Fischer, Lyndal Henden, Ulrich Müller, Daniela Steinberger, Esther Leshinsky-Silver, Armand Bottani, Timea Kurdiova, Jozef Ukropec, Olga Nyitrayova, Miriam Kolnikova, Iwar Klimes, Guntram Borck, Melanie Bahlo, Stefan A. Haas, Joo-Ran Kim, Leda E. Lotspeich-Cole, Daniela Gasperikova, Thomas E. Dever, Vera M. Kalscheuer

Hum Mutat. Author manuscript; available in PMC 2018 Nov 30.

Published in final edited form as: Hum Mutat. 2017 Apr; 38(4): 409–425. Published online 2017 Jan 23. doi: 10.1002/humu.23170

PMCID:: PMC6267786

Abstract Article PDF–2.0M

Select item 14616515.

Minimum requirements for the function of eukaryotic translation initiation factor 2.

F L Erickson, J Nika, S Rippel, E M Hannig

Genetics. 2001 May; 158(1): 123–132. doi: 10.1093/genetics/158.1.123

PMCID:: PMC1461651

Summary PDF–408K

Select item 12229066.

Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.

Nilce N Hashimoto, Larissa S Carnevalli, Beatriz A Castilho

Biochem J. 2002 Oct 15; 367(Pt 2): 359–368. doi: 10.1042/BJ20020556

PMCID:: PMC1222906

Summary PDF–373K

Select item 4524547.

Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit.

F L Erickson, E M Hannig

EMBO J. 1996 Nov 15; 15(22): 6311–6320.

PMCID:: PMC452454

Summary Page Browse PDF–2.2M

Select item 85998448.

Large-scale movement of eIF3 domains during translation initiation modulate start codon selection

Jose L Llácer, Tanweer Hussain, Jinsheng Dong, Laura Villamayor, Yuliya Gordiyenko, Alan G Hinnebusch

Nucleic Acids Res. 2021 Nov 18; 49(20): 11491–11511. Published online 2021 Oct 14. doi: 10.1093/nar/gkab908

PMCID:: PMC8599844

Abstract Article PDF–6.6M

Select item 63448769.

MEHMO syndrome mutation EIF2S3-I259M impairs initiator Met-tRNA_i^Met binding to eukaryotic translation initiation factor eIF2

Sara K Young-Baird, Byung-Sik Shin, Thomas E Dever

Nucleic Acids Res. 2019 Jan 25; 47(2): 855–867. Published online 2018 Dec 4. doi: 10.1093/nar/gky1213

PMCID:: PMC6344876

Abstract Article PDF–2.4M

Select item 8387610.

The β Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C₂-C₂ Motif

Jomar P. Laurino, Glória M. Thompson, Eliza Pacheco, Beatriz A. Castilho

Mol Cell Biol. 1999 Jan; 19(1): 173–181. doi: 10.1128/mcb.19.1.173

Correction in:: Mol Cell Biol. 1999 Apr; 19(4): 3224.

PMCID:: PMC83876

Abstract Article PDF–1021K

Select item 1123086811.

eIF2β zinc-binding domain interacts with the eIF2γ subunit through the guanine nucleotide binding interface to promote Met-tRNA_i^Met binding

Aranyadip Gayen, Pankaj V. Alone

Biosci Rep. 2024 Jul 31; 44(7): BSR20240438. Published online 2024 Jul 5. doi: 10.1042/BSR20240438

PMCID:: PMC11230868

Abstract Article PDF–8.7M

Select item 398613512.

Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation

Margarito Rojas, Anne-Claude Gingras, Thomas E. Dever

Proc Natl Acad Sci U S A. 2014 Apr 8; 111(14): E1344–E1353. Published online 2014 Mar 24. doi: 10.1073/pnas.1400129111

PMCID:: PMC3986135

Abstract Article PDF–1.4M

Select item 355398513.

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA

Marie Naveau, Christine Lazennec-Schurdevin, Michel Panvert, Etienne Dubiez, Yves Mechulam, Emmanuelle Schmitt

Nucleic Acids Res. 2013 Jan; 41(2): 1047–1057. Published online 2012 Nov 26. doi: 10.1093/nar/gks1180

PMCID:: PMC3553985

Abstract Article PDF–5.2M

Select item 257331014.

Translation Initiation Factor 2γ Mutant Alters Start Codon Selection Independent of Met-tRNA Binding

Pankaj V. Alone, Chune Cao, Thomas E. Dever

Mol Cell Biol. 2008 Nov; 28(22): 6877–6888. Published online 2008 Sep 15. doi: 10.1128/MCB.01147-08

PMCID:: PMC2573310

Abstract Article PDF–1.2M

Select item 122100615.

Conserved sequences in the beta subunit of archaeal and eukaryal translation initiation factor 2 (eIF2), absent from eIF5, mediate interaction with eIF2gamma.

G M Thompson, E Pacheco, E O Melo, B A Castilho

Biochem J. 2000 May 1; 347(Pt 3): 703–709.

PMCID:: PMC1221006

Summary PDF–205K

Select item 31651216.

GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae

Han-kuei Huang, Heejeong Yoon, Ernest M. Hannig, Thomas F. Donahue

Genes Dev. 1997 Sep 15; 11(18): 2396–2413. doi: 10.1101/gad.11.18.2396

PMCID:: PMC316512

Abstract Article PDF–932K

Select item 337171117.

A systematic study of gene expression variation at single-nucleotide resolution reveals widespread regulatory roles for uAUGs

Yue Yun, T.M. Ayodele Adesanya, Robi D. Mitra

Genome Res. 2012 Jun; 22(6): 1089–1097. doi: 10.1101/gr.117366.110

PMCID:: PMC3371711

Abstract Article PDF–6.2M

Select item 115696818.

Eukaryotic Translation Initiation Factor 5 Is Critical for Integrity of the Scanning Preinitiation Complex and Accurate Control of GCN4 Translation

Chingakham Ranjit Singh, Cynthia Curtis, Yasufumi Yamamoto, Nathan S. Hall, Dustin S. Kruse, Hui He, Ernest M. Hannig, Katsura Asano

Mol Cell Biol. 2005 Jul; 25(13): 5480–5491. doi: 10.1128/MCB.25.13.5480-5491.2005

PMCID:: PMC1156968

Abstract Article PDF–818K

Select item 372461419.

Translation Initiation Requires Cell Division Cycle 123 (Cdc123) to Facilitate Biogenesis of the Eukaryotic Initiation Factor 2 (eIF2)

Angelika F. Perzlmaier, Frank Richter, Wolfgang Seufert

J Biol Chem. 2013 Jul 26; 288(30): 21537–21546. Published online 2013 Jun 17. doi: 10.1074/jbc.M113.472290

PMCID:: PMC3724614

Abstract Article PDF–2.4M

Select item 195195920.

Critical Contacts between the Eukaryotic Initiation Factor 2B (eIF2B) Catalytic Domain and both eIF2β and -2γ Mediate Guanine Nucleotide Exchange

Sarah S. Mohammad-Qureshi, Raphaël Haddad, Elizabeth J. Hemingway, Jonathan P. Richardson, Graham D. Pavitt

Mol Cell Biol. 2007 Jul; 27(14): 5225–5234. doi: 10.1128/MCB.00495-07

PMCID:: PMC1951959

Abstract Article PDF–476K

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