PMC Links for Gene (Select 8654) - PMC

Links from Gene

Items: 1 to 20 of 46

<< First< Prev

Page of 3

Select item 93687581.

Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms

Silvia Cardarelli, Adriana Erica Miele, Federica Campolo, Mara Massimi, Patrizia Mancini, Stefano Biagioni, Fabio Naro, Mauro Giorgi, Michele Saliola

Int J Mol Sci. 2022 Aug; 23(15): 8587. Published online 2022 Aug 2. doi: 10.3390/ijms23158587

PMCID:: PMC9368758

Abstract Article PDF–2.3M

Select item 89662012.

Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice

Daniela Puzzo, Carla Loreto, Salvatore Giunta, Giuseppe Musumeci, Giuseppina Frasca, Maria Vittoria Podda, Ottavio Arancio, Agostino Palmeri

Neurobiol Aging. Author manuscript; available in PMC 2022 Mar 30.

Published in final edited form as: Neurobiol Aging. 2014 Mar; 35(3): 520–531. Published online 2013 Oct 7. doi: 10.1016/j.neurobiolaging.2013.09.002

PMCID:: PMC8966201

Abstract Article PDF–1.0M

Select item 67041193.

Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms

Valeriana Cesarini, Calogera Pisano, Gabriele Rossi, Carmela Rita Balistreri, Flavia Botti, Giorgio Antonelli, Giovanni Ruvolo, Emmanuele A. Jannini, Susanna Dolci

Sci Rep. 2019; 9: 12206. Published online 2019 Aug 21. doi: 10.1038/s41598-019-48432-6

PMCID:: PMC6704119

Abstract Article PDF–3.1M

Select item 54348964.

Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux

Anna Subbotina, Aina W. Ravna, Roy A. Lysaa, Ruben Abagyan, Ryszard Bugno, Georg Sager

J Pharm Pharmacol. 2017 Jun; 69(6): 675–683. Published online 2017 Feb 17. doi: 10.1111/jphp.12693

PMCID:: PMC5434896

Abstract Article PDF–785K

Select item 53550915.

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

Valeriana Cesarini, Maurizio Martini, Lucia Ricci Vitiani, Giovanni Luca Gravina, Silvia Di Agostino, Grazia Graziani, Quintino Giorgio D'Alessandris, Roberto Pallini, Luigi M Larocca, Pellegrino Rossi, Emmanuele A Jannini, Susanna Dolci

Oncotarget. 2017 Feb 21; 8(8): 13223–13239. Published online 2017 Jan 14. doi: 10.18632/oncotarget.14656

PMCID:: PMC5355091

Abstract Article PDF–9.1M

Select item 49278846.

PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease

Andrew F. Teich, Mikako Sakurai, Mitesh Patel, Cameron Holman, Faisal Saeed, Jole Fiorito, Ottavio Arancio

J Alzheimers Dis. 2016; 52(1): 295–302. Prepublished online 2016 Mar 9. Published online 2016 Apr 26. doi: 10.3233/JAD-151104

PMCID:: PMC4927884

Abstract Article PDF–30M

Select item 43144387.

Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage

Emma E. M. Knowles, D. Reese McKay, Jack W. Kent, Jr, Emma Sprooten, Melanie A. Carless, Joanne E. Curran, Marcio A. A. de Almeida, Thomas D. Dyer, Harald H. H. Göring, Rene Olvera, Ravi Duggirala, Peter Fox, Laura Almasy, John Blangero, David. C. Glahn

Am J Psychiatry. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Am J Psychiatry. 2015 Feb 1; 172(2): 190–199. Published online 2014 Oct 31. doi: 10.1176/appi.ajp.2014.14030311

PMCID:: PMC4314438

Abstract Article PDF–460K

Select item 41724858.

Role of Ser102 and Ser104 as Regulators of cGMP Hydrolysis by PDE5A

Julie Carøe Nordgaard, Lars Schack Kruse, Steen Gammeltoft, Christina Rostrup Kruuse

PLoS One. 2014; 9(9): e107627. Published online 2014 Sep 23. doi: 10.1371/journal.pone.0107627

PMCID:: PMC4172485

Abstract Article PDF–526K

Select item 33664679.

Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5

Shaquria P. Adderley, Kelly M. Thuet, Meera Sridharan, Elizabeth A. Bowles, Alan H. Stephenson, Mary L. Ellsworth, Randy S. Sprague

Med Sci Monit. 2011; 17(5): CR241–CR247. Published online 2011 May 1. doi: 10.12659/MSM.881763

PMCID:: PMC3366467

Abstract Article PDF–636K

Select item 304873710.

Distinct Allostery Induced in the Cyclic GMP-binding, Cyclic GMP-specific Phosphodiesterase (PDE5) by Cyclic GMP, Sildenafil, and Metal Ions

Kabir H. Biswas, Sandhya S. Visweswariah

J Biol Chem. 2011 Mar 11; 286(10): 8545–8554. Published online 2010 Dec 29. doi: 10.1074/jbc.M110.193185

PMCID:: PMC3048737

Abstract Article PDF–3.4M

Select item 299224811.

Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain

Huanchen Wang, Howard Robinson, Hengming Ke

J Biol Chem. 2010 Dec 3; 285(49): 38149–38156. Published online 2010 Sep 21. doi: 10.1074/jbc.M110.141614

PMCID:: PMC2992248

Abstract Article PDF–1.6M

Select item 293602312.

Signalling pathways involved in sildenafil-induced relaxation of human bladder dome smooth muscle

S Oger, D Behr-Roussel, D Gorny, T Lebret, P Validire, X Cathelineau, L Alexandre, F Giuliano

Br J Pharmacol. 2010 Jul; 160(5): 1135–1143. doi: 10.1111/j.1476-5381.2010.00748.x

PMCID:: PMC2936023

Abstract Article PDF–312K

Select item 217335913.

Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling

Florian Mullershausen, Andreas Friebe, Robert Feil, W. Joseph Thompson, Franz Hofmann, Doris Koesling

J Cell Biol. 2003 Mar 3; 160(5): 719–727. doi: 10.1083/jcb.200211041

PMCID:: PMC2173359

Abstract Article PDF–295K

Select item 51533714.

In Vivo Reconstitution of the Negative Feedback in Nitric Oxide/cGMP Signaling: Role of Phosphodiesterase Type 5 Phosphorylation

Florian Mullershausen, Michael Russwurm, Doris Koesling, Andreas Friebe

Mol Biol Cell. 2004 Sep; 15(9): 4023–4030. doi: 10.1091/mbc.E03-12-0890

PMCID:: PMC515337

Abstract Article PDF–256K

Select item 1104078415.

CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1

Kai Lei, Ruihao Liang, Jialu Liang, Nan Lu, Jing Huang, Ke Xu, Binghua Tan, Kexi Wang, Yicheng Liang, Wenjian Wang, Huayue Lin, Minghui Wang

J Exp Clin Cancer Res. 2024; 43: 124. Published online 2024 Apr 24. doi: 10.1186/s13046-024-03054-3

PMCID:: PMC11040784

Abstract Article PDF–18M

Select item 800127316.

Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition

Clarissa Corinaldesi, Rebecca L. Ross, Giuseppina Abignano, Cristina Antinozzi, Francesco Marampon, Luigi di Luigi, Maya H. Buch, Valeria Riccieri, Andrea Lenzi, Clara Crescioli, Francesco Del Galdo

Int J Mol Sci. 2021 Mar; 22(6): 2894. Published online 2021 Mar 12. doi: 10.3390/ijms22062894

PMCID:: PMC8001273

Abstract Article PDF–1.6M

Select item 770157117.

Changes in the expression and function of the PDE5 pathway in the obstructed urinary bladder

Weixiang He, Han Xiang, Daoquan Liu, Jianmin Liu, Mingzhou Li, Qian Wang, Qiaofeng Qian, Yan Li, Xun Fu, Ping Chen, Yuming Guo, Guang Zeng, Zhonghua Wu, Daxing Zhan, Xinghuan Wang, Michael E. DiSanto, Xinhua Zhang

J Cell Mol Med. 2020 Nov; 24(22): 13181–13195. Published online 2020 Oct 3. doi: 10.1111/jcmm.15926

PMCID:: PMC7701571

Abstract Article PDF–3.2M

Select item 746056018.

Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death against Human Non-Small Cell Lung Cancers

Ya-Ching Chang, Yu-Ling Tseng, Wohn-Jenn Leu, Chi-Min Du, Yi-Huei Jiang, Lih-Ching Hsu, Jui-Ling Hsu, Duen-Ren Hou, Jih-Hwa Guh

Int J Mol Sci. 2020 Aug; 21(16): 5608. Published online 2020 Aug 5. doi: 10.3390/ijms21165608

PMCID:: PMC7460560

Abstract Article PDF–3.4M

Select item 469499819.

Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10

Nan Li, Xi Chen, Bing Zhu, Verónica Ramírez-Alcántara, Joshua C. Canzoneri, Kevin Lee, Sara Sigler, Bernard Gary, Yonghe Li, Wei Zhang, Mary P. Moyer, E. Alan Salter, Andrzej Wierzbicki, Adam B. Keeton, Gary A. Piazza

Oncotarget. 2015 Sep 29; 6(29): 27403–27415. Published online 2015 Jul 25. doi: 10.18632/oncotarget.4741

PMCID:: PMC4694998

Abstract Article PDF–2.8M

Select item 467474120.

Upregulation of Phosphodiesterase type 5 in the Hyperplastic Prostate

Wenhao Zhang, Ning Zang, Yaoming Jiang, Ping Chen, Xinghuan Wang, Xinhua Zhang

Sci Rep. 2015; 5: 17888. Published online 2015 Dec 10. doi: 10.1038/srep17888

PMCID:: PMC4674741

Abstract Article PDF–1.5M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 46

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity