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Select item 111451181.

Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells

Yukihiro Sato, Minoru Kobayashi, Masahiro Ohira, Ryo Funayama, Masamitsu Maekawa, Hideaki Karasawa, Ryosuke Kashiwagi, Yayoi Aoyama, Nariyasu Mano, Shinobu Ohnuma, Michiaki Unno, Keiko Nakayama

Cancer Sci. 2024 Jun; 115(6): 1778–1790. Published online 2024 Apr 2. doi: 10.1111/cas.16132

PMCID:: PMC11145118

Abstract Article PDF–8.8M

Select item 72840322.

Prevalence of ABCC3‐1767G/A polymorphism among patients with antiretroviral‐associated hepatotoxicity

HariOm Singh, Sonam Lata, Ranjana Choudhari, Tapan N. Dhole

Mol Genet Genomic Med. 2020 Jun; 8(6): e1124. Published online 2020 Mar 25. doi: 10.1002/mgg3.1124

PMCID:: PMC7284032

Abstract Article PDF–503K

Select item 49599963.

ABCC3 Genetic Variants are Associated with Postoperative Morphine-induced Respiratory Depression and Morphine Pharmacokinetics in Children

Vidya Chidambaran, Raja Venkatasubramanian, Xue Zhang, Lisa J. Martin, Jing Niu, Tomoyuki Mizuno, Tsuyoshi Fukuda, Jaroslaw Meller, Alexander A. Vinks, Senthilkumar Sadhasivam

Pharmacogenomics J. Author manuscript; available in PMC 2017 Mar 24.

Published in final edited form as: Pharmacogenomics J. 2017 Mar; 17(2): 162–169. Published online 2016 Jan 26. doi: 10.1038/tpj.2015.98

PMCID:: PMC4959996

Abstract Article PDF–942K

Select item 48727794.

MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma

Tetsu Tomonari, Shunsaku Takeishi, Tatsuya Taniguchi, Takahiro Tanaka, Hironori Tanaka, Shota Fujimoto, Tetsuo Kimura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma, Tetsuji Takayama

Oncotarget. 2016 Feb 9; 7(6): 7207–7215. Published online 2016 Jan 12. doi: 10.18632/oncotarget.6889

PMCID:: PMC4872779

Abstract Article PDF–2.1M

Select item 48651445.

Role of the Drug Transporter ABCC3 in Breast Cancer Chemoresistance

Sai A. Balaji, Nayanabhirama Udupa, Mallikarjuna Rao Chamallamudi, Vaijayanti Gupta, Annapoorni Rangarajan

PLoS One. 2016; 11(5): e0155013. Published online 2016 May 12. doi: 10.1371/journal.pone.0155013

PMCID:: PMC4865144

Abstract Article PDF–3.4M

Select item 42790866.

Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene

Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto, Nathan J. Cherrington

Drug Metab Dispos. 2015 Jan; 43(1): 93–99. Published online 2015 Jan. doi: 10.1124/dmd.114.060103

PMCID:: PMC4279086

Abstract Article PDF–484K

Select item 38145867.

ABCC3 as a marker for multidrug resistance in non-small cell lung cancer

Yanbin Zhao, Hailing Lu, An Yan, Yanmei Yang, Qingwei Meng, Lichun Sun, Hui Pang, Chunhong Li, Xiaoqun Dong, Li Cai

Sci Rep. 2013; 3: 3120. Published online 2013 Nov 1. doi: 10.1038/srep03120

PMCID:: PMC3814586

Abstract Article PDF–635K

Select item 28788888.

Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas

Chien-Tsun Kuan, Nidhi Srivastava, Roger E. McLendon, Wayne A. Marasco, Michael R. Zalutsky, Darell D. Bigner

Int J Cancer. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Int J Cancer. 2010 Aug 1; 127(3): 598–611. doi: 10.1002/ijc.25062

PMCID:: PMC2878888

Abstract Article PDF–850K

Select item 220169.

MRP3, an organic anion transporter able to transport anti-cancer drugs

Marcel Kool, Marcel van der Linden, Marcel de Haas, George L. Scheffer, J. Marleen L. de Vree, Alexander J. Smith, Gerrit Jansen, Godefridus J. Peters, Nico Ponne, Rik J. Scheper, Ronald P. J. Oude Elferink, Frank Baas, Piet Borst

Proc Natl Acad Sci U S A. 1999 Jun 8; 96(12): 6914–6919. doi: 10.1073/pnas.96.12.6914

PMCID:: PMC22016

Abstract Article PDF–297K

Select item 895111510.

Association Study of SLCO1B3 and ABCC3 Genetic Variants in Gallstone Disease

Bolesław Banach, Andrzej Modrzejewski, Zygmunt Juzyszyn, Mateusz Kurzawski, Tomasz Sroczynski, Andrzej Pawlik

Genes (Basel) 2022 Mar; 13(3): 512. Published online 2022 Mar 14. doi: 10.3390/genes13030512

PMCID:: PMC8951115

Abstract Article PDF–241K

Select item 707549411.

Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney

Cindy Yanfei Li, Abdul Basit, Anshul Gupta, Zsuzsanna Gáborik, Emese Kis, Bhagwat Prasad

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2019 Jul; 191: 105350. Published online 2019 Apr 5. doi: 10.1016/j.jsbmb.2019.03.027

PMCID:: PMC7075494

Abstract Article PDF–1.4M

Select item 537232612.

Pregnane X receptor is associated with unfavorable survival and induces chemotherapeutic resistance by transcriptional activating multidrug resistance-related protein 3 in colorectal cancer

Yan Dong, Zhe Wang, Gan-feng Xie, Chong Li, Wen-wei Zuo, Gang Meng, Cheng-ping Xu, Jian-jun Li

Mol Cancer. 2017; 16: 71. Published online 2017 Mar 29. doi: 10.1186/s12943-017-0641-8

PMCID:: PMC5372326

Abstract Article PDF–4.8M

Select item 519896013.

Wnt‐β‐catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer

Minoru Kobayashi, Ryo Funayama, Shinobu Ohnuma, Michiaki Unno, Keiko Nakayama

Cancer Sci. 2016 Dec; 107(12): 1776–1784. Published online 2016 Dec 13. doi: 10.1111/cas.13097

PMCID:: PMC5198960

Abstract Article PDF–3.1M

Select item 442968214.

Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis

Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson, Nathan J. Cherrington

Drug Metab Dispos. 2015 Jun; 43(6): 829–835. Published online 2015 Jun. doi: 10.1124/dmd.114.062703

PMCID:: PMC4429682

Abstract Article PDF–685K

Select item 419007515.

ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children

Raja Venkatasubramanian, Tsuyoshi Fukuda, Jing Niu, Tomoyuki Mizuno, Vidya Chidambaran, Alexander A Vinks, Senthilkumar Sadhasivam

Pharmacogenomics. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Pharmacogenomics. 2014 Jul; 15(10): 1297–1309. doi: 10.2217/pgs.14.99

PMCID:: PMC4190075

Abstract Article PDF–784K

Select item 354671116.

Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure

Consolación Melguizo, Jose Prados, Raquel Luque, Raúl Ortiz, Octavio Caba, Pablo J. Álvarez, Beatriz Gonzalez, Antonia Aranega

Int J Mol Sci. 2012; 13(12): 16624–16635. Published online 2012 Dec 5. doi: 10.3390/ijms131216624

PMCID:: PMC3546711

Abstract Article PDF–458K

Select item 318923517.

Effect of ABCB1 and ABCC3 Polymorphisms on Osteosarcoma Survival after Chemotherapy: A Pharmacogenetic Study

Daniela Caronia, Ana Patiño-Garcia, Antonio Peréz-Martínez, Guillermo Pita, Leticia Tais Moreno, Marta Zalacain-Díez, Blanca Molina, Isabel Colmenero, Luis Sierrasesúmaga, Javier Benítez, Anna Gonzalez-Neira

PLoS One. 2011; 6(10): e26091. Published online 2011 Oct 7. doi: 10.1371/journal.pone.0026091

PMCID:: PMC3189235

Abstract Article PDF–137K

Select item 269287318.

Multidrug Resistant Protein-Three Gene Regulation by the Transcription Factor Nrf2 in Human Bronchial Epithelial and Non-Small Cell Lung Carcinoma

Christopher M. Mahaffey, Hongqiao Zhang, Alessandra Rinna, William Holland, Philip C. Mack, Henry Jay Forman

Free Radic Biol Med. Author manuscript; available in PMC 2010 Jun 15.

Published in final edited form as: Free Radic Biol Med. 2009 Jun 15; 46(12): 1650–1657. Published online 2009 Apr 5. doi: 10.1016/j.freeradbiomed.2009.03.023

PMCID:: PMC2692873

Abstract Article PDF–1.7M

Select item 122305419.

Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter.

Noam Zelcer, Tohru Saeki, Ilse Bot, Annemieke Kuil, Piet Borst

Biochem J. 2003 Jan 1; 369(Pt 1): 23–30. doi: 10.1042/BJ20021081

PMCID:: PMC1223054

Summary PDF–200K

Select item 874498020.

The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes

Karolina Seborova, Alzbeta Kloudova-Spalenkova, Kamila Koucka, Petr Holy, Marie Ehrlichova, Changwei Wang, Iwao Ojima, Iveta Voleska, Petr Daniel, Kamila Balusikova, Michael Jelinek, Jan Kovar, Lukas Rob, Martin Hruda, Marcela Mrhalova, Pavel Soucek, Radka Vaclavikova

Int J Mol Sci. 2022 Jan; 23(1): 73. Published online 2021 Dec 22. doi: 10.3390/ijms23010073