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Items: 1 to 20 of 32

1.
Prognostic and immunological roles of IL18RAP in human cancers
Wu Chen, Tianbao Song, Fan Zou, Yuqi Xia, Ji Xing, Weimin Yu, Ting Rao, Xiangjun Zhou, Chenglong Li, Jinzhuo Ning, Sheng Zhao, Yuan Ruan, Fan Cheng
Aging (Albany NY) 2023 Sep 15; 15(17): 9059–9085. Published online 2023 Sep 11. doi: 10.18632/aging.205017
PMCID:
PMC10522399
AbstractArticlePDF–6.8M
2.
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3′UTR protect against ALS
Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R. van Eijk, Matthieu Moisse, Sali M. K. Farhan, Yehuda M. Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy Sarah Yacovzada, Shu-Ting Hung, Johnathan Cooper-Knock, Chien-Hsiung Yu, Cynthia Louis, Seth L. Masters, Kevin P. Kenna, Rick A. A. van der Spek, William Sproviero, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Ashley R. Jones, Yael Elbaz-Alon, Yahel Cohen, Elik Chapnik, Daphna Rothschild, Omer Weissbrod, Gilad Beck, Elena Ainbinder, Shifra Ben-Dor, Sebastian Werneburg, Dorothy P. Schafer, Robert H. Brown, Jr, Pamela J. Shaw, Philip Van Damme, Leonard H. van den Berg, Hemali Phatnani, Eran Segal, Justin K. Ichida, Ammar Al-Chalabi, Jan H. Veldink, Project MinE ALS Sequencing Consortium , NYGC ALS Consortium , Eran Hornstein
Nat Neurosci. Author manuscript; available in PMC 2023 Aug 9.
Published in final edited form as: Nat Neurosci. 2022 Apr 1; 25(4): 433–445. Published online 2022 Mar 31. doi: 10.1038/s41593-022-01040-6
PMCID:
PMC7614916
AbstractArticlePDF–4.8M
3.
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response
Svetlana Cherlin, Myles J Lewis, Darren Plant, Nisha Nair, Katriona Goldmann, Evan Tzanis, Michael R Barnes, Paul McKeigue, Jennifer H Barrett, Costantino Pitzalis, Anne Barton, MATURA Consortium, Heather J Cordell
Ann Rheum Dis. 2020 Nov; 79(11): 1446–1452. Published online 2020 Jul 30. doi: 10.1136/annrheumdis-2020-217204
PMCID:
PMC7569378
AbstractArticlePDF–1.6M
4.
Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease
V M Salvati, T T MacDonald, M Bajaj-Elliott, M Borrelli, A Staiano, S Auricchio, R Troncone, G Monteleone
Gut. 2002 Feb; 50(2): 186–190. doi: 10.1136/gut.50.2.186
PMCID:
PMC1773110
AbstractArticlePDF–220K
5.
A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling
Suzhao Li, Liqiong Jiang, Karsten Beckmann, Jesper Falkesgaard Højen, Ulrich Pessara, Nicholas E. Powers, Dennis M. de Graaf, Tania Azam, Jared Lindenberger, Elan Z. Eisenmesser, Stephan Fischer, Charles A. Dinarello
J Biol Chem. 2021 Jan-Jun; 296: 100630. Published online 2021 Apr 3. doi: 10.1016/j.jbc.2021.100630
PMCID:
PMC8018910
AbstractArticlePDF–1.1M
6.
Are IL18RAP gene polymorphisms associated with body mass regulation? A cross-sectional study
Vanesa Martínez-Barquero, Griselda de Marco, Sergio Martínez-Hervas, Victoria Adam-Felici, Cristina Pérez-Soriano, Verónica Gonzalez-Albert, Gemma Rojo, Juan Francisco Ascaso, José Tomás Real, Ana Barbara Garcia-Garcia, Juan Carlos Martín-Escudero, Raquel Cortes, Felipe Javier Chaves
BMJ Open. 2017; 7(11): e017875. Published online 2017 Nov 15. doi: 10.1136/bmjopen-2017-017875
PMCID:
PMC5695454
AbstractArticlePDF–621K
7.
Genetic analysis of innate immunity in Behcet’s disease identifies an association with IL-37 and IL-18RAP
Handan Tan, Bolin Deng, Hongsong Yu, Yi Yang, Lin Ding, Qi Zhang, Jieying Qin, Aize Kijlstra, Rui Chen, Peizeng Yang
Sci Rep. 2016; 6: 35802. Published online 2016 Oct 24. doi: 10.1038/srep35802
PMCID:
PMC5075872
AbstractArticlePDF–446K
8.
The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC
Courtney B. Myhr, Maigan A. Hulme, Clive H. Wasserfall, Peter J. Hong, Priya Saikumar Lakshmi, Desmond A. Schatz, Michael J. Haller, Todd M. Brusko, Mark A. Atkinson
J Autoimmun. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: J Autoimmun. 2013 Aug; 44: 8–12. Published online 2013 Jul 24. doi: 10.1016/j.jaut.2013.06.001
PMCID:
PMC3775347
AbstractArticlePDF–613K
9.
IL-18R1 and IL-18RAP SNPs may associate with Bronchopulmonary Dysplasia in African American infants
Joanna Floros, Douglas Londono, Derek Gordon, Patricia Silveyra, Susan L Diangelo, Rose M Viscardi, George S Worthen, Jeffrey Shenberger, Guirong Wang, Zhenwu Lin, Neal J Thomas
Pediatr Res. Author manuscript; available in PMC 2013 Mar 28.
Published in final edited form as: Pediatr Res. 2012 Jan; 71(1): 107–114. doi: 10.1038/pr.2011.14
PMCID:
PMC3610412
AbstractArticlePDF–2.8M
10.
Genetic Analysis of Innate Immunity in Crohn's Disease and Ulcerative Colitis Identifies Two Susceptibility Loci Harboring CARD9 and IL18RAP
Alexandra Zhernakova, Eleanora M. Festen, Lude Franke, Gosia Trynka, Cleo C. van Diemen, Alienke J. Monsuur, Marianna Bevova, Rian M. Nijmeijer, Ruben van ‘t Slot, Roel Heijmans, H. Marike Boezen, David A. van Heel, Adriaan A. van Bodegraven, Pieter C.F. Stokkers, Cisca Wijmenga, J. Bart A. Crusius, Rinse K. Weersma
Am J Hum Genet. 2008 May 9; 82(5): 1202–1210. Published online 2008 May 2. doi: 10.1016/j.ajhg.2008.03.016
PMCID:
PMC2427314
AbstractArticlePDF–181K
11.
The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling Through Innate Receptor-Initiated Pathways
Matija Hedl, Shasha Zheng, Clara Abraham
J Immunol. Author manuscript; available in PMC 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 Jun 15; 192(12): 5924–5932. Published online 2014 May 19. doi: 10.4049/jimmunol.1302727
PMCID:
PMC4146459
AbstractArticlePDF–1.9M
12.
Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project
Marie-Lise Grisoni, Carole Proust, Mervi Alanne, Maylis DeSuremain, Veikko Salomaa, Kari Kuulasmaa, François Cambien, Viviane Nicaud, Per-Gunnar Wiklund, Jarmo Virtamo, Frank Kee, Laurence Tiret, Alun Evans, David-Alexandre Tregouet
BMC Med Genet. 2009; 10: 44. Published online 2009 May 27. doi: 10.1186/1471-2350-10-44
PMCID:
PMC2692850
AbstractArticlePDF–609K
13.
The structural basis for receptor recognition of human interleukin-18
Naotaka Tsutsumi, Takeshi Kimura, Kyohei Arita, Mariko Ariyoshi, Hidenori Ohnishi, Takahiro Yamamoto, Xiaobing Zuo, Katsumi Maenaka, Enoch Y. Park, Naomi Kondo, Masahiro Shirakawa, Hidehito Tochio, Zenichiro Kato
Nat Commun. 2014 Dec 15; 5: 5340. Published online 2014 Dec 15. doi: 10.1038/ncomms6340
PMCID:
PMC4275594
AbstractArticlePDF–3.6M
14.
TRAM Is Involved in IL-18 Signaling and Functions as a Sorting Adaptor for MyD88
Hidenori Ohnishi, Hidehito Tochio, Zenichiro Kato, Norio Kawamoto, Takeshi Kimura, Kazuo Kubota, Takahiro Yamamoto, Tatsuyoshi Funasaka, Hiroshi Nakano, Richard W. Wong, Masahiro Shirakawa, Naomi Kondo
PLoS One. 2012; 7(6): e38423. Published online 2012 Jun 7. doi: 10.1371/journal.pone.0038423
PMCID:
PMC3369926
AbstractArticlePDF–2.2M
15.
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling
Jennifer E. Ho, Wei-Yu Chen, Ming-Huei Chen, Martin G. Larson, Elizabeth L. McCabe, Susan Cheng, Anahita Ghorbani, Erin Coglianese, Valur Emilsson, Andrew D. Johnson, Stefan Walter, Nora Franceschini, Christopher J. O’Donnell, CARDIoGRAM Consortium, CHARGE Inflammation Working Group, Abbas Dehghan, Chen Lu, Daniel Levy, Christopher Newton-Cheh, CHARGE Heart Failure Working Group, Honghuang Lin, Janine F. Felix, Eric R. Schreiter, Ramachandran S. Vasan, James L. Januzzi, Richard T. Lee, Thomas J. Wang
J Clin Invest. 2013 Oct 1; 123(10): 4208–4218. Published online 2013 Sep 3. doi: 10.1172/JCI67119
PMCID:
PMC3784527
AbstractArticlePDF–1.4M
16.
Allelic variants of IL1R1 gene associate with severe hand osteoarthritis
Annu Näkki, Sanna T Kouhia, Janna Saarela, Arsi Harilainen, Kaj Tallroth, Tapio Videman, Michele C Battié, Jaakko Kaprio, Leena Peltonen, Urho M Kujala
BMC Med Genet. 2010; 11: 50. Published online 2010 Mar 30. doi: 10.1186/1471-2350-11-50
PMCID:
PMC2859817
AbstractArticlePDF–1.1M
17.
Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects
Kai Wang, Robert Baldassano, Haitao Zhang, Hui-Qi Qu, Marcin Imielinski, Subra Kugathasan, Vito Annese, Marla Dubinsky, Jerome I. Rotter, Richard K. Russell, Jonathan P. Bradfield, Patrick M.A. Sleiman, Joseph T. Glessner, Thomas Walters, Cuiping Hou, Cecilia Kim, Edward C. Frackelton, Maria Garris, James Doran, Claudio Romano, Carlo Catassi, Johan Van Limbergen, Stephen L. Guthery, Lee Denson, David Piccoli, Mark S. Silverberg, Charles A. Stanley, Dimitri Monos, David C. Wilson, Anne Griffiths, Struan F.A. Grant, Jack Satsangi, Constantin Polychronakos, Hakon Hakonarson
Hum Mol Genet. 2010 May 15; 19(10): 2059–2067. Published online 2010 Feb 22. doi: 10.1093/hmg/ddq078
PMCID:
PMC2860894
AbstractArticlePDF–166K
18.
Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis
Anne Hinks, Paul Martin, Edward Flynn, Steve Eyre, Jon Packham, Anne Barton, Childhood Arthritis Prospective Study (CAPS), UKRAG Consortium, BSPAR study group, Jane Worthington, Wendy Thomson
Ann Rheum Dis. 2010 Dec 1; 69(12): 2169–2172. Published online 2010 Jul 20. doi: 10.1136/ard.2009.126938
PMCID:
PMC3002762
AbstractArticlePDF–547K
19.
Novel celiac disease genetic determinants related to the immune response
Karen A Hunt, Alexandra Zhernakova, Graham Turner, Graham A.R. Heap, Lude Franke, Marcel Bruinenberg, Jihane Romanos, Lotte C. Dinesen, Anthony W Ryan, Davinder Panesar, Rhian Gwilliam, Fumihiko Takeuchi, William M McLaren, Geoffrey KT Holmes, Peter D Howdle, Julian RF Walters, David S Sanders, Raymond J Playford, Gosia Trynka, Chris JJ Mulder, M Luisa Mearin, Wieke HM Verbeek, Valerie Trimble, Fiona M Stevens, Colm O’Morain, Nicholas P Kennedy, Dermot Kelleher, Daniel J Pennington, David P Strachan, Wendy L McArdle, Charles A Mein, Martin C Wapenaar, Panos Deloukas, Ralph McGinnis, Ross McManus, Cisca Wijmenga, David A van Heel
Nat Genet. Author manuscript; available in PMC 2009 Apr 27.
Published in final edited form as: Nat Genet. 2008 Apr; 40(4): 395–402. Published online 2008 Mar 2. doi: 10.1038/ng.102
PMCID:
PMC2673512
AbstractArticlePDF–1.1M
20.
Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
Deborah J Smyth, Vincent Plagnol, Neil M Walker, Jason D Cooper, Kate Downes, Jennie HM Yang, Joanna MM Howson, Helen Stevens, Ross McManus, Cisca Wijmenga, Graham A. Heap, Patrick C. Dubois, David G. Clayton, Karen A Hunt, David A van Heel, John A Todd
N Engl J Med. Author manuscript; available in PMC 2010 Mar 17.
Published in final edited form as: N Engl J Med. 2008 Dec 25; 359(26): 2767–2777. Published online 2008 Dec 10. doi: 10.1056/NEJMoa0807917
PMCID:
PMC2840835
AbstractArticlePDF–451K

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