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Select item 106927001.

Dual roles of cellular communication network factor 6 (CCN6) in the invasion and metastasis of oral cancer cells to bone via binding to BMP2 and RANKL

Hiroaki Hochi, Satoshi Kubota, Masaharu Takigawa, Takashi Nishida

Carcinogenesis. 2023 Aug-Sep; 44(8-9): 695–707. Published online 2023 Aug 17. doi: 10.1093/carcin/bgad057

PMCID:: PMC10692700

Abstract Article PDF–15M

Select item 73367552.

CCN6 mutation detection in Chinese patients with progressive pseudo‐rheumatoid dysplasia and identification of four novel mutations

Yingjie Wang, Ke Xiao, Yuemei Yang, Zhihong Wu, Jin Jin, Guixing Qiu, Xisheng Weng, Xiuli Zhao

Mol Genet Genomic Med. 2020 Jul; 8(7): e1261. Published online 2020 Apr 29. doi: 10.1002/mgg3.1261

PMCID:: PMC7336755

Abstract Article PDF–1.6M

Select item 64399833.

Progressive Pseudorheumatoid Dysplasia resolved by whole exome sequencing: a novel mutation in WISP3 and review of the literature

Ben Pode-Shakked, Asaf Vivante, Ortal Barel, Shai Padeh, Dina Marek-Yagel, Alvit Veber, Shachar Abudi, Aviva Eliyahu, Irit Tirosh, Shiri Shpilman, Shirlee Shril, Friedhelm Hildebrandt, Mordechai Shohat, Yair Anikster

BMC Med Genet. 2019; 20: 53. Published online 2019 Mar 29. doi: 10.1186/s12881-019-0787-x

PMCID:: PMC6439983

Abstract Article PDF–789K

Select item 57937764.

WISP3 mutation associated with pseudorheumatoid dysplasia

M. Reza Sailani, James Chappell, Inlora Jingga, Anil Narasimha, Amin Zia, Janet Linnea Lynch, Safoura Mazrouei, Jonathan A. Bernstein, Omid Aryani, Michael P. Snyder

Cold Spring Harb Mol Case Stud. 2018 Feb; 4(1): a001990. doi: 10.1101/mcs.a001990

PMCID:: PMC5793776

Abstract Article PDF–3.0M

Select item 50418965.

The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells

Wei Huang, Emily E. Martin, Boris Burman, Maria E. Gonzalez, Celina G. Kleer

Oncotarget. 2016 May 3; 7(18): 25180–25193. Published online 2016 Feb 25. doi: 10.18632/oncotarget.7734

PMCID:: PMC5041896

Abstract Article PDF–1.8M

Select item 50094476.

An argument for early genomic sequencing in atypical cases: a WISP3 variant leads to diagnosis of progressive pseudorheumatoid arthropathy of childhood

Christopher A. Cassa, Stacy E. Smith, William Docken, Erin Hoffman, Heather McLaughlin, Sung Chun, Ignaty Leshchiner, Hichem Miraoui, Soumya Raychaudhuri, Natasha Y. Frank, Brian J. Wilson, Shamil R. Sunyaev, Richard L. Maas, the Brigham Genomic Medicine, Dana Vuzman

Rheumatology (Oxford) 2016 Mar; 55(3): 586–589. Published online 2015 Oct 22. doi: 10.1093/rheumatology/kev367

PMCID:: PMC5009447

Article PDF–117K

Select item 49043727.

Whole Exome Screening Identifies Novel and Recurrent WISP3 Mutations Causing Progressive Pseudorheumatoid Dysplasia in Jammu and Kashmir-India

Ekta Rai, Ankit Mahajan, Parvinder Kumar, Arshia Angural, Manoj K Dhar, Sushil Razdan, Kumarasamy Thangaraj, Carol A. Wise, Shiro Ikegawa, Kamal Kishore Pandita, Swarkar Sharma

Sci Rep. 2016; 6: 27684. Published online 2016 Jun 13. doi: 10.1038/srep27684

PMCID:: PMC4904372

Abstract Article PDF–745K

Select item 35061828.

CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer

Anupama Pal, Wei Huang, Xin Li, Kathy A. Toy, Zaneta Nikolovska-Coleska, Celina G. Kleer

Cancer Res. Author manuscript; available in PMC 2013 Sep 15.

Published in final edited form as: Cancer Res. 2012 Sep 15; 72(18): 4818–4828. Published online 2012 Jul 17. doi: 10.1158/0008-5472.CAN-12-0154

PMCID:: PMC3506182

Abstract Article PDF–2.4M

Select item 33698449.

Novel and Recurrent Mutations of WISP3 in Two Chinese Families with Progressive Pseudorheumatoid Dysplasia

Jing Sun, Weibo Xia, Shuli He, Zhen Zhao, Min Nie, Mei Li, Yan Jiang, Xiaoping Xing, Ou Wang, Xunwu Meng, Xueying Zhou

PLoS One. 2012; 7(6): e38643. Published online 2012 Jun 7. doi: 10.1371/journal.pone.0038643

PMCID:: PMC3369844

Abstract Article PDF–16M

Select item 336617210.

Dual regulation of metalloproteinase expression in chondrocytes by WISP3/CCN6

Natasha Baker, Paul Sharpe, Kirsty Culley, Miguel Otero, Damon Bevan, Peter Newham, Wendy Barker, Kristen M Clements, Caroline J Langham, Mary B Goldring, Jelena Gavrilovic

Arthritis Rheum. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Arthritis Rheum. 2012 Jul; 64(7): 2289–2299. doi: 10.1002/art.34411

PMCID:: PMC3366172

Abstract Article PDF–1.2M

Select item 285612711.

Blockade of CCN6 (WISP3) Activates Growth Factor-Independent Survival and Resistance to Anoikis in Human Mammary Epithelial Cells

Wei Huang, Maria E. Gonzalez, Kathy Toy, Mousumi Banerjee, Celina G. Kleer

Cancer Res. Author manuscript; available in PMC 2011 Apr 15.

Published in final edited form as: Cancer Res. 2010 Apr 15; 70(8): 3340–3350. doi: 10.1158/0008-5472.CAN-09-4225

PMCID:: PMC2856127

Abstract Article PDF–2.1M

Select item 141077112.

Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells

Yanhong Zhang, Quintin Pan, Hui Zhong, Sofia D Merajver, Celina G Kleer

Breast Cancer Res. 2005; 7(6): R1080–R1089. Published online 2005 Nov 8. doi: 10.1186/bcr1351

PMCID:: PMC1410771

Abstract Article PDF–1.1M

Select item 1044497113.

OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6

Ying Zhao, Jing Ruan, Zhongding Li, Xian Su, Kangmin Chen, Yimin Lin, Yuepiao Cai, Peng Wang, Baohua Liu, Dirk Schlüter, Guang Liang, Xu Wang

Clin Transl Med. 2023 Aug; 13(8): e1385. Published online 2023 Aug 22. doi: 10.1002/ctm2.1385

PMCID:: PMC10444971

Abstract Article PDF–6.0M

Select item 653642214.

Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of β‐catenin/TCF/LEF signalling

Hong Gao, Fen‐Fen Yin, Dong‐Xian Guan, Yu‐Xiong Feng, Qian‐Wen Zheng, Xiang Wang, Min Zhu, Xue‐Li Zhang, Shu‐Qun Cheng, Tian‐Wei Chen, Hao Jiang, Er‐Bin Zhang, Jing‐Jing Wang, Qian‐Zhi Ni, Yan‐Mei Yuan, Feng‐Kun Zhang, Ning Ma, Hui‐Jun Cao, Yi‐Kang Wang, Jing‐Jing Li, Dong Xie

Cell Prolif. 2019 May; 52(3): e12583. Published online 2019 Feb 22. doi: 10.1111/cpr.12583

PMCID:: PMC6536422

Abstract Article PDF–2.0M

Select item 642672815.

Cyr61和WISP-3在非小细胞肺癌组织中的表达及其临床意义

吕建发, 邹友成, 张纯伟, 毛志福

Zhongguo Fei Ai Za Zhi. 2010 Dec 20; 13(12): 1122–1126. Chinese. doi: 10.3779/j.issn.1009-3419.2010.12.08

PMCID:: PMC6426728

Abstract Article PDF–873K

Select item 423011716.

Silencing of WISP3 suppresses gastric cancer cell proliferation and metastasis and inhibits Wnt/β-catenin signaling

Fang Fang, Wen-Yi Zhao, Rong-Kun Li, Xiao-Mei Yang, Jun Li, Jun-Ping Ao, Shu-Heng Jiang, Fan-Zhi Kong, Lin Tu, Chun Zhuang, Wen-Xin Qin, Ping He, Wen-Ming Zhang, Hui Cao, Zhi-Gang Zhang

Int J Clin Exp Pathol. 2014; 7(10): 6447–6461. Published online 2014 Sep 15.