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Select item 91157691.

Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury

Alison W Ha, Tao Bai, David L Ebenezer, Tanvi Sethi, Tara Sudhadevi, Lizar Ace Mangio, Steven Garzon, Gloria S Pryhuber, Viswanathan Natarajan, Anantha Harijith

Thorax. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Thorax. 2022 Jan; 77(1): 47–57. Published online 2021 Apr 21. doi: 10.1136/thoraxjnl-2020-216469

PMCID:: PMC9115769

Abstract Article PDF–1.5M

Select item 82726292.

Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation

Jean-Philip Truman, Christian F. Ruiz, Magali Trayssac, Cungui Mao, Yusuf A. Hannun, Lina M. Obeid

FASEB J. Author manuscript; available in PMC 2021 Jul 10.

Published in final edited form as: FASEB J. 2021 Feb; 35(2): e21284. doi: 10.1096/fj.202001814RR

PMCID:: PMC8272629

Abstract Article PDF–2.4M

Select item 80880753.

Activation of SphK1 by adipocytes mediates epithelial ovarian cancer cell proliferation

Lan Dai, Chen Wang, Keqi Song, Wenjing Wang, Wen Di

J Ovarian Res. 2021; 14: 62. Published online 2021 May 1. doi: 10.1186/s13048-021-00815-y

PMCID:: PMC8088075

Abstract Article PDF–1.3M

Select item 78826414.

Sphingosine kinase 1 is associated with immune cell-related gene expressions in human breast cancer

Junko Tsuchida, Masayuki Nagahashi, Masato Nakajima, Eriko Katsuta, Omar M Rashid, Qianya Qi, Li Yan, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai

J Surg Res. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Surg Res. 2020 Dec; 256: 645–656. Published online 2020 Aug 15. doi: 10.1016/j.jss.2020.06.057

PMCID:: PMC7882641

Abstract Article PDF–1.7M

Select item 78066675.

Erythrocyte sphingosine kinase regulates intraerythrocytic development of Plasmodium falciparum

Raj Kumar Sah, Soumya Pati, Monika Saini, Shailja Singh

Sci Rep. 2021; 11: 1257. Published online 2021 Jan 13. doi: 10.1038/s41598-020-80658-7

PMCID:: PMC7806667

Abstract Article PDF–10M

Select item 72263006.

Sphingosine Kinase Blockade Leads to Increased Natural Killer T Cell Responses to Mantle Cell Lymphoma

Michael S. Lee, Wenji Sun, Tonya J. Webb

Cells. 2020 Apr; 9(4): 1030. Published online 2020 Apr 21. doi: 10.3390/cells9041030

PMCID:: PMC7226300

Abstract Article PDF–2.7M

Select item 69783457.

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

Caroline Imbert, Anne Montfort, Marine Fraisse, Elie Marcheteau, Julia Gilhodes, Elodie Martin, Florie Bertrand, Marlène Marcellin, Odile Burlet-Schiltz, Anne Gonzalez de Peredo, Virginie Garcia, Stéphane Carpentier, Sophie Tartare-Deckert, Pierre Brousset, Philippe Rochaix, Florent Puisset, Thomas Filleron, Nicolas Meyer, Laurence Lamant, Thierry Levade, Bruno Ségui, Nathalie Andrieu-Abadie, Céline Colacios

Nat Commun. 2020; 11: 437. Published online 2020 Jan 23. doi: 10.1038/s41467-019-14218-7

PMCID:: PMC6978345

Abstract Article PDF–1.9M

Select item 68225788.

miRNA-103 promotes chondrocyte apoptosis by down-regulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis

Fang Li, Jianhua Yao, Qingqing Hao, Zheping Duan

Biosci Rep. 2019 Oct 30; 39(10): BSR20191255. Published online 2019 Oct 18. doi: 10.1042/BSR20191255

PMCID:: PMC6822578

Abstract Article PDF–1.2M

Select item 66976209.

Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer

Sunil Acharya, Jun Yao, Ping Li, Chenyu Zhang, Frank J. Lowery, Qingling Zhang, Hua Guo, Jingkun Qu, Fei Yang, Ignacio I. Wistuba, Helen Piwnica-Worms, Aysegul A. Sahin, Dihua Yu

Cancer Res. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Cancer Res. 2019 Aug 15; 79(16): 4211–4226. Published online 2019 Jun 25. doi: 10.1158/0008-5472.CAN-18-3803

PMCID:: PMC6697620

Abstract Article PDF–1.8M

Select item 647648310.

Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription

Min Kyung Kim, Wooseong Lee, Gang-Ho Yoon, Eun-Ju Chang, Sun-Cheol Choi, Seong Who Kim

BMB Rep. 2019 Mar; 52(3): 220–225. Published online 2019 Mar 31. doi: 10.5483/BMBRep.2019.52.3.012

PMCID:: PMC6476483

Abstract Article PDF–1.3M

Select item 643682611.

Molecular Mechanisms of Regulation of Sphingosine Kinase 1

Michael J. Pulkoski-Gross, Lina M. Obeid

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Nov; 1863(11): 1413–1422. Published online 2018 Aug 30. doi: 10.1016/j.bbalip.2018.08.015

PMCID:: PMC6436826

Abstract Article PDF–1.5M

Select item 627562012.

Chronic increases in sphingosine kinase-1 activity induce a pro-inflammatory, pro-angiogenic phenotype in endothelial cells

Vidya Limaye, Pu Xia, Chris Hahn, Malcolm Smith, Mathew A. Vadas, Stuart M. Pitson, Jennifer R. Gamble

Cell Mol Biol Lett. 2009 Sep; 14(3): 424–441. Published online 2009 Feb 23. doi: 10.2478/s11658-009-0009-1

PMCID:: PMC6275620

Summary PDF–7.3M

Select item 625493013.

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial-mesenchymal transition mediated by the FAK/AKT/MMPs axis

Shi-Quan Liu, Chun-Yan Xu, Wen-Hong Wu, Zhen-Hua Fu, Si-Wei He, Meng-Bin Qin, Jie-An Huang

Int J Oncol. 2019 Jan; 54(1): 41–52. Published online 2018 Oct 25. doi: 10.3892/ijo.2018.4607

PMCID:: PMC6254930

Abstract Article PDF–2.5M

Select item 620890814.

Field template-based design and biological evaluation of new sphingosine kinase 1 inhibitors

Heba Alshaker, Shyam Srivats, Danielle Monteil, Qi Wang, Caroline M. R. Low, Dmitri Pchejetski

Breast Cancer Res Treat. 2018; 172(1): 33–43. Published online 2018 Jul 24. doi: 10.1007/s10549-018-4900-1

PMCID:: PMC6208908

Abstract Article PDF–1.5M

Select item 600035315.

SPHK1在调节小细胞肺癌多药耐药中的作用

杨兰, 胡洪林, 邓颖, 白义凤

Zhongguo Fei Ai Za Zhi. 2014 Nov 20; 17(11): 769–777. Chinese. doi: 10.3779/j.issn.1009-3419.2014.11.01

PMCID:: PMC6000353

Abstract Article PDF–1.3M

Select item 583292216.

An intrinsic lipid-binding interface controls sphingosine kinase 1 function

Michael J. Pulkoski-Gross, Meredith L. Jenkins, Jean-Philip Truman, Mohamed F. Salama, Christopher J. Clarke, John E. Burke, Yusuf A. Hannun, Lina M. Obeid

J Lipid Res. 2018 Mar; 59(3): 462–474. Published online 2018 Jan 11. doi: 10.1194/jlr.M081307