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Select item 78795091.

Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin

Christoph Roser, Csaba Tóth, Marcus Renner, Esther Herpel, Peter Schirmacher

Cell Commun Signal. 2021; 19: 15. Published online 2021 Feb 12. doi: 10.1186/s12964-020-00702-x

PMCID:: PMC7879509

Abstract Article PDF–1.9M

Select item 54141562.

The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling

Csaba Toth, Sarah Funke, Vanessa Nitsche, Anna Liverts, Viktoriya Zlachevska, Marcia Gasis, Constanze Wiek, Helmut Hanenberg, Csaba Mahotka, Peter Schirmacher, Sebastian Heikaus

Cell Commun Signal. 2017; 15: 16. Published online 2017 May 2. doi: 10.1186/s12964-017-0170-5

PMCID:: PMC5414156

Abstract Article PDF–2.8M

Select item 34311913.

Familial Cortical Myoclonus with a Mutation in NOL3

Jonathan F. Russell, Jamie L. Steckley, Giovanni Coppola, Angelika F.G. Hahn, MacKenzie A. Howard, Zachary Kornberg, Alden Huang, Seyed M. Mirsattari, Barry Merriman, Eric Klein, Murim Choi, Hsien-Yang Lee, Andrew Kirk, Carol Nelson-Williams, Gillian Gibson, Scott C. Baraban, Richard P. Lifton, Daniel H. Geschwind, Ying-Hui Fu, Louis J. Ptáček

Ann Neurol. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Ann Neurol. 2012 Aug; 72(2): 175–183. doi: 10.1002/ana.23666

PMCID:: PMC3431191

Abstract Article PDF–1.1M

Select item 30350724.

Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML

Bing Z. Carter, Yi Hua Qiu, Nianxiang Zhang, Kevin R. Coombes, Duncan H. Mak, Deborah A. Thomas, Farhad Ravandi, Hagop M. Kantarjian, Erich Koller, Michael Andreeff, Steven M. Kornblau

Blood. 2011 Jan 20; 117(3): 780–787. Prepublished online 2010 Nov 1. doi: 10.1182/blood-2010-04-280503

PMCID:: PMC3035072

Abstract Article

Select item 53396835.

A myeloid tumor suppressor role for NOL3

Robert F. Stanley, Richard T. Piszczatowski, Boris Bartholdy, Kelly Mitchell, Wendy M. McKimpson, Swathi Narayanagari, Dagmar Walter, Tihomira I. Todorova, Cassandra Hirsch, Hideki Makishima, Britta Will, Christine McMahon, Kira Gritsman, Jaroslaw P. Maciejewski, Richard N. Kitsis, Ulrich Steidl

J Exp Med. 2017 Mar 6; 214(3): 753–771. doi: 10.1084/jem.20162089

PMCID:: PMC5339683

Abstract Article PDF–3.5M

Select item 42993756.

Constant rate of p53 tetramerization in response to DNA damage controls the p53 response

Giorgio Gaglia, Galit Lahav

Mol Syst Biol. 2014 Oct 1; 10(10): 1–8. Published online 2014 Oct 24. doi: 10.15252/msb.20145168

PMCID:: PMC4299375

Abstract Article PDF–1.5M

Select item 40013037.

MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain

Q Li, J-X Wang, Y-Q He, C Feng, X-J Zhang, J-Q Sheng, P-F Li

Cell Death Dis. 2014 Apr; 5(4): e1197. Published online 2014 Apr 24. doi: 10.1038/cddis.2014.148

PMCID:: PMC4001303

Abstract Article PDF–1.6M

Select item 32457428.

Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis and chemoresistance

Christina M. Medina-Ramirez, Sumanta Goswami, Tatiana Smirnova, Daniel Bamira, Benjamin Benson, Neal Ferrick, Jeffrey Segall, Jeffrey W. Pollard, Richard N. Kitsis

Cancer Res. Author manuscript; available in PMC 2012 Dec 15.

Published in final edited form as: Cancer Res. 2011 Dec 15; 71(24): 7705–7715. Published online 2011 Oct 28. doi: 10.1158/0008-5472.CAN-11-2192

PMCID:: PMC3245742

Abstract Article PDF–2.6M

Select item 45831469.

A Critical Role for the Anti-apoptotic Protein ARC (Apoptosis Repressor with CARD) in Hypoxia-Induced Pulmonary Hypertension

Ari L Zaiman, Rachel Damico, Alan Thoms-Chesley, D Clark Files, Priya Kesari, Laura Johnston, Mara Swaim, Shehzin Mozammel, Alan C Myers, Marc Halushka, Hasim El-Haddad, Larissa A Shimoda, Chang-Fu Peng, Paul M Hassoun, Hunter C Champion, Richard N Kitsis, Michael T Crow

Circulation. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Circulation. 2011 Dec 6; 124(23): 2533–2542. Published online 2011 Nov 14. doi: 10.1161/CIRCULATIONAHA.111.034512

PMCID:: PMC4583146

Abstract Article PDF–2.5M

Select item 435740010.

Apoptosis suppressor ARC modulates SMAC mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia

Po Yee Mak, Duncan H. Mak, Vivian Ruvolo, Rodrigo Jacamo, Steven M. Kornblau, Michael Andreeff, Bing Z. Carter

Br J Haematol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Br J Haematol. 2014 Nov; 167(3): 376–384. Published online 2014 Jul 31. doi: 10.1111/bjh.13054

Correction in:: Br J Haematol. 2015 Nov; 171(3): 440.

PMCID:: PMC4357400

Abstract Article PDF–1.9M

Select item 352603611.

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Wendy M. McKimpson, Jeremy Weinberger, Lech Czerski, Min Zheng, Michael T. Crow, Jeffrey E. Pessin, Streamson C. Chua, Jr., Richard N. Kitsis

Diabetes. 2013 Jan; 62(1): 183–193. Published online 2012 Dec 13. doi: 10.2337/db12-0504

PMCID:: PMC3526036

Abstract Article PDF–2.5M

Select item 288520212.

Induction of the Apoptosis Inhibitor ARC by Ras in Human Cancers

Lily Wu, Young-Jae Nam, Gloria Kung, Michael T. Crow, Richard N. Kitsis

J Biol Chem. 2010 Jun 18; 285(25): 19235–19245. Published online 2010 Apr 14. doi: 10.1074/jbc.M110.114892

PMCID:: PMC2885202

Abstract Article PDF–3.7M

Select item 240922613.

Regulation of p53 tetramerization and nuclear export by ARC

Roger S.-Y. Foo, Young-Jae Nam, Marc Jason Ostreicher, Mark D. Metzl, Russell S. Whelan, Chang-Fu Peng, Anthony W. Ashton, Weimin Fu, Kartik Mani, Suet-Feung Chin, Elena Provenzano, Ian Ellis, Nichola Figg, Sarah Pinder, Martin R. Bennett, Carlos Caldas, Richard N. Kitsis

Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52): 20826–20831. Published online 2007 Dec 17. doi: 10.1073/pnas.0710017104

PMCID:: PMC2409226

Abstract Article PDF–1.3M

Select item 52547314.

Calcium Binding of ARC Mediates Regulation of Caspase 8 and Cell Death

Dong-Gyu Jo, Joon-Il Jun, Jae-Woong Chang, Yeon-Mi Hong, Sungmin Song, Dong-Hyung Cho, Sang Mi Shim, Ho-June Lee, Chunghee Cho, Do Han Kim, Yong-Keun Jung

Mol Cell Biol. 2004 Nov; 24(22): 9763–9770. doi: 10.1128/MCB.24.22.9763-9770.2004

PMCID:: PMC525473

Abstract Article PDF–527K

Select item 497136115.

Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice

Stefan Donath, Junfeng An, Sabrina Lin Lin Lee, Karen Gertz, Anna Lena Datwyler, Ulrike Harms, Susanne Müller, Tracy Deanne Farr, Martina Füchtemeier, Gisela Lättig-Tünnemann, Janet Lips, Marco Foddis, Larissa Mosch, René Bernard, Ulrike Grittner, Mustafa Balkaya, Golo Kronenberg, Ulrich Dirnagl, Matthias Endres, Christoph Harms

J Neurosci. 2016 Aug 3; 36(31): 8132–8148. doi: 10.1523/JNEUROSCI.4428-15.2016

PMCID:: PMC4971361

Abstract Article PDF–4.7M

Select item 2023016.

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

Takeyoshi Koseki, Naohiro Inohara, Shu Chen, Gabriel Núñez

Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9): 5156–5160. doi: 10.1073/pnas.95.9.5156

PMCID:: PMC20230

Abstract Article PDF–378K

Select item 292822417.

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity

HD Hosgood, III, L Zhang, M Shen, SI Berndt, R Vermeulen, G Li, S Yin, M Yeager, J Yuenger, N Rothman, S Chanock, M Smith, Q Lan

Occup Environ Med. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Occup Environ Med. 2009 Dec; 66(12): 848–853. Published online 2009 Sep 22. doi: 10.1136/oem.2008.044024

PMCID:: PMC2928224

Abstract Article PDF–321K

Select item 303367218.

Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells

Ok-Hee Lee, Hyeung Kim, Quanyuan He, Hwa Jin Baek, Dong Yang, Liuh-Yow Chen, Jiancong Liang, Heekyung Kate Chae, Amin Safari, Dan Liu, Zhou Songyang

Mol Cell Proteomics. 2011 Feb; 10(2): M110.001628. Published online 2010 Nov 11. doi: 10.1074/mcp.M110.001628

PMCID:: PMC3033672

Abstract Article PDF–1.5M

Select item 276866719.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

Ji Luo, Michael J. Emanuele, Danan Li, Chad J. Creighton, Michael R. Schlabach, Thomas F. Westbrook, Kwok-kin Wong, Stephen J. Elledge

Cell. Author manuscript; available in PMC 2009 Nov 29.

Published in final edited form as: Cell. 2009 May 29; 137(5): 835–848. doi: 10.1016/j.cell.2009.05.006

PMCID:: PMC2768667

Abstract Article PDF–4.0M

Select item 563060020.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

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