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Select item 39373881.

Sphingosine Kinase 1 and Cancer: A Systematic Review and Meta-Analysis

Yun Zhang, Yan Wang, Zhi Wan, Shiping Liu, Yu Cao, Zhi Zeng

PLoS One. 2014; 9(2): e90362. Published online 2014 Feb 27. doi: 10.1371/journal.pone.0090362

PMCID:: PMC3937388

Abstract Article PDF–1.8M

Select item 29866322.

Evidence for association with hepatocellular carcinoma at the PAPSS1 locus on chromosome 4q25 in a family-based study

Wei-Liang Shih, Ming-Whei Yu, Pei-Jer Chen, Tai-Wei Wu, Chih-Lin Lin, Chun-Jen Liu, Shi-Ming Lin, Dar-In Tai, Shou-Dong Lee, Yun-Fan Liaw

Eur J Hum Genet. 2009 Oct; 17(10): 1250–1259. Published online 2009 Apr 1. doi: 10.1038/ejhg.2009.48

PMCID:: PMC2986632

Abstract Article PDF–262K

Select item 29092873.

Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro

Viviana Anelli, Christopher R. Gault, Ashley J. Snider, Lina M. Obeid

FASEB J. 2010 Aug; 24(8): 2727–2738. doi: 10.1096/fj.09-150540

PMCID:: PMC2909287

Abstract Article

Select item 25764444.

The Host Cell Sulfonation Pathway Contributes to Retroviral Infection at a Step Coincident with Provirus Establishment

James W. Bruce, Paul Ahlquist, John A. T. Young

PLoS Pathog. 2008 Nov; 4(11): e1000207. Published online 2008 Nov 14. doi: 10.1371/journal.ppat.1000207

PMCID:: PMC2576444

Abstract Article PDF–790K

Select item 104861355.

The PAPSS1 gene is a modulator of response to cisplatin by regulating estrogen receptor alpha signaling activity in ovarian cancer cells

Lei Sun, Wei-Xue Ji, Yan Li, Ze-Lian Li, Can-Can Duan, Bai-rong Xia, Lan Xiao

J Ovarian Res. 2023; 16: 187. Published online 2023 Sep 8. doi: 10.1186/s13048-023-01262-7

PMCID:: PMC10486135

Abstract Article PDF–9.0M

Select item 76850836.

Effect of estrogen sulfation by SULT1E1 and PAPSS on the development of estrogen‐dependent cancers

Yali Xu, Xiaoxia Liu, Fenghua Guo, Yanxia Ning, Xiuling Zhi, Xinhong Wang, Sifeng Chen, Lianhua Yin, Xiaobo Li

Cancer Sci. 2012 Jun; 103(6): 1000–1009. Published online 2012 Apr 11. doi: 10.1111/j.1349-7006.2012.02258.x

PMCID:: PMC7685083

Abstract Article PDF–995K

Select item 44684357.

Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation

Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek, Melissa Runge-Morris

Drug Metab Dispos. 2015 Jul; 43(7): 1061–1070. Published online 2015 Jul. doi: 10.1124/dmd.114.061440

PMCID:: PMC4468435

Abstract Article PDF–672K

Select item 43031108.

Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway

Heba Alshaker, Jonathan Krell, Adam E Frampton, Jonathan Waxman, Oleg Blyuss, Alexey Zaikin, Mathias Winkler, Justin Stebbing, Ernesto Yagüe, Dmitri Pchejetski

Breast Cancer Res. 2014; 16: 426. Published online 2014 Oct 25. doi: 10.1186/s13058-014-0426-6

PMCID:: PMC4303110

Abstract Article PDF–1.7M

Select item 12226799.

Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.

Hirotoshi Fuda, Chikara Shimizu, Young C Lee, Harukuni Akita, Charles A Strott

Biochem J. 2002 Jul 15; 365(Pt 2): 497–504. doi: 10.1042/BJ20020044

PMCID:: PMC1222679

Summary PDF–336K

Select item 541808010.

CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1

Wenying Zhu, Briony L. Gliddon, Kate E. Jarman, Paul A. B. Moretti, Teresa Tin, Leslie V. Parise, Joanna M. Woodcock, Jason A. Powell, Andrew Ruszkiewicz, Melissa R. Pitman, Stuart M. Pitson

Oncogene. Author manuscript; available in PMC 2017 Jun 12.

Published in final edited form as: Oncogene. 2017 May 4; 36(18): 2619–2627. Published online 2016 Dec 12. doi: 10.1038/onc.2016.428

PMCID:: PMC5418080

Abstract Article PDF–1.3M

Select item 325233911.

Human PAPS Synthase Isoforms Are Dynamically Regulated Enzymes with Access to Nucleus and Cytoplasm

Elisabeth Schröder, Lena Gebel, Andrey A. Eremeev, Jessica Morgner, Daniel Grum, Shirley K. Knauer, Peter Bayer, Jonathan W. Mueller

PLoS One. 2012; 7(1): e29559. Published online 2012 Jan 5. doi: 10.1371/journal.pone.0029559

PMCID:: PMC3252339

Abstract Article PDF–865K

Select item 2113612.

A member of a family of sulfate-activating enzymes causes murine brachymorphism

Kiyoto Kurima, Matthew L. Warman, Srinivasan Krishnan, Miriam Domowicz, Richard C. Krueger, Jr., Andrea Deyrup, Nancy B. Schwartz

Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15): 8681–8685. doi: 10.1073/pnas.95.15.8681

Correction in:: Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20): 12070.

PMCID:: PMC21136

Abstract Article PDF–347K

Select item 389456713.

Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family Study

Joseph H. Lee, Rong Cheng, Lawrence S. Honig, Mary Feitosa, Candace M. Kammerer, Min S. Kang, Nicole Schupf, Shiow J. Lin, Jason L. Sanders, Harold Bae, Todd Druley, Thomas Perls, Kaare Christensen, Michael Province, Richard Mayeux

Front Genet. 2013; 4: 310. Published online 2014 Jan 17. doi: 10.3389/fgene.2013.00310

PMCID:: PMC3894567

Abstract Article PDF–960K

Select item 287244314.

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

Haoqiang Ying, Hongwu Zheng, Kenneth Scott, Ruprecht Wiedemeyer, Haiyan Yan, Carol Lim, Joseph Huang, Sabin Dhakal, Elena Ivanova, Yonghong Xiao, Hailei Zhang, Jian Hu, Jayne M. Stommel, Michelle A. Lee, An-Jou Chen, Ji-Hye Paik, Oreste Segatto, Cameron Brennan, Lisa A. Elferink, Y. Alan Wang, Lynda Chin, Ronald A. DePinho

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 6912–6917. Published online 2010 Mar 29. doi: 10.1073/pnas.0914930107

PMCID:: PMC2872443

Abstract Article PDF–967K

Select item 287688415.

A systematic gene-based screen of chr4q22–q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts

Gursharan Kalsi, Po-Hsiu Kuo, Fazil Aliev, Jeffry Alexander, Omari McMichael, Diana G. Patterson, Dermot Walsh, Zhongming Zhao, Marc Schuckit, John Nurnberger, Jr, Howard Edenberg, John Kramer, Vladimir Vladimirov, Carol A. Prescott, Danielle M. Dick, Kenneth S. Kendler, Brien P. Riley

Hum Mol Genet. 2010 Jun 15; 19(12): 2497–2506. Published online 2010 Mar 23. doi: 10.1093/hmg/ddq112

Correction in:: Hum Mol Genet. 2010 Oct 15; 19(20): 4121.

PMCID:: PMC2876884

Abstract Article PDF–226K

Select item 671971816.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Abstract Article PDF–1.3M

Select item 636858417.

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang

Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3

PMCID:: PMC6368584

Abstract Article PDF–6.8M

Select item 876007718.

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord

Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6

PMCID:: PMC8760077

Abstract Article PDF–12M

Select item 737208119.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Abstract Article PDF–2.0M

Select item 875541920.

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

Yuzheng Zhou, Rong Zheng, Sixu Liu, Cyrollah Disoma, Ashuai Du, Shiqin Li, Zongpeng Chen, Zijun Dong, Yongxing Zhang, Sijia Li, Pinjia Liu, Aroona Razzaq, Xuan Chen, Yujie Liao, Siyi Tao, Yuxin Liu, Lunan Xu, Qianjun Zhang, Jian Peng, Xu Deng, Shanni Li, Taijiao Jiang, Zanxian Xia

J Biol Chem. 2022 Feb; 298(2): 101584. Published online 2022 Jan 13. doi: 10.1016/j.jbc.2022.101584

PMCID:: PMC8755419

Abstract Article PDF–3.5M

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