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Select item 43238451.

Membrane-mediated Actions of 1,25-Dihydroxy Vitamin D3: A Review of the Roles of Phospholipase A₂ Activating Protein and Ca²⁺/Calmodulin-dependent Protein Kinase II

Maryam Doroudi, Zvi Schwartz, Barbara D. Boyan

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2015 Mar; 0: 81–84. Published online 2014 Nov 6. doi: 10.1016/j.jsbmb.2014.11.002

PMCID:: PMC4323845

Abstract Article PDF–1.0M

Select item 27291332.

ALTERATION IN THE ACTIVATION STATE OF NEW INFLAMMATION-ASSOCIATED TARGETS BY PHOSPHOLIPASE A₂-ACTIVATING PROTEIN (PLAA)

Fan Zhang, Jian Sha, Thomas. G. Wood, Cristi. L. Galindo, Harold R. Garner, Mark. F. Burkart, Giovanni Suarez, Johanna. C. Sierra, Stacy. L. Agar, Johnny W. Peterson, Ashok K. Chopra

Cell Signal. Author manuscript; available in PMC 2009 Aug 19.

Published in final edited form as: Cell Signal. 2008 May; 20(5): 844–861. Published online 2008 Jan 17. doi: 10.1016/j.cellsig.2008.01.004

PMCID:: PMC2729133

Abstract Article PDF–3.2M

Select item 94180043.

PLAA suppresses ovarian cancer metastasis via METTL3-mediated m⁶A modification of TRPC3 mRNA

Zhangjin Shen, Lingkai Gu, Yuwan Liu, Lingfang Wang, Jiawei Zhu, Sangsang Tang, Xinyi Wei, Jiaying Wang, Songfa Zhang, Xinyu Wang, Xiaodong Cheng, Xing Xie, Weiguo Lu

Oncogene. 2022; 41(35): 4145–4158. Published online 2022 Jul 22. doi: 10.1038/s41388-022-02411-w

PMCID:: PMC9418004

Abstract Article PDF–6.5M

Select item 58410544.

Phospholipase A₂-activating protein is associated with a novel form of leukoencephalopathy

Tzipora C Falik Zaccai, David Savitzki, Yifat Zivony-Elboum, Thierry Vilboux, Eric C Fitts, Yishay Shoval, Limor Kalfon, Nadra Samra, Zohar Keren, Bella Gross, Natalia Chasnyk, Rachel Straussberg, James C Mullikin, Jamie K Teer, Dan Geiger, Daniel Kornitzer, Ora Bitterman-Deutsch, Abraham O Samson, Maki Wakamiya, Johnny W Peterson, Michelle L Kirtley, Iryna V Pinchuk, Wallace B Baze, William A Gahl, Robert Kleta, Yair Anikster, Ashok K Chopra

Brain. 2017 Feb; 140(2): 370–386. Published online 2016 Dec 21. doi: 10.1093/brain/aww295

PMCID:: PMC5841054

Abstract Article PDF–1.7M

Select item 32249945.

Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort

Lavinia Athanasiu, Morten Mattingsdal, Anna K. Kähler, Andrew Brown, Omar Gustafsson, Ingrid Agartz, Ina Giegling, Pierandrea Muglia, Sven Cichon, Marcella Rietschel, Olli P.H. Pietiläinen, Leena Peltonen, Elvira Bramon, David Collier, David St. Clair, Engilbert Sigurdsson, Hannes Petursson, Dan Rujescu, Ingrid Melle, Vidar M. Steen, Srdjan Djurovic, Ole A. Andreassen

J Psychiatr Res. Author manuscript; available in PMC 2011 Nov 28.

Published in final edited form as: J Psychiatr Res. 2010 Sep; 44(12): 748–753. Published online 2010 Feb 24. doi: 10.1016/j.jpsychires.2010.02.002

PMCID:: PMC3224994

Abstract Article PDF–420K

Select item 27072046.

Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A₂-activating Protein

Qing-Shan Fu, Chen-Jie Zhou, Hong-Chang Gao, Ya-Jun Jiang, Zi-Ren Zhou, Jing Hong, Wen-Ming Yao, Ai-Xin Song, Dong-Hai Lin, Hong-Yu Hu

J Biol Chem. 2009 Jul 10; 284(28): 19043–19052. Published online 2009 May 7. doi: 10.1074/jbc.M109.009126

PMCID:: PMC2707204

Abstract Article PDF–3.8M

Select item 28041847.

Structure and Function of the PLAA/Ufd3-p97/Cdc48 Complex

Liyan Qiu, Natasha Pashkova, John R. Walker, Stanley Winistorfer, Abdellah Allali-Hassani, Masato Akutsu, Robert Piper, Sirano Dhe-Paganon

J Biol Chem. 2010 Jan 1; 285(1): 365–372. Published online 2009 Nov 2. doi: 10.1074/jbc.M109.044685

PMCID:: PMC2804184

Abstract Article PDF–3.5M

Select item 518848.

Cloning of a phospholipase A2-activating protein.

M A Clark, L E Ozgür, T M Conway, J Dispoto, S T Crooke, J S Bomalaski

Proc Natl Acad Sci U S A. 1991 Jun 15; 88(12): 5418–5422. doi: 10.1073/pnas.88.12.5418

PMCID:: PMC51884

Summary Page Browse PDF–1.1M

Select item 999709.

Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways

Daphné Seigneurin-Berny, André Verdel, Sandrine Curtet, Claudie Lemercier, Jérôme Garin, Sophie Rousseaux, Saadi Khochbin

Mol Cell Biol. 2001 Dec; 21(23): 8035–8044. doi: 10.1128/MCB.21.23.8035-8044.2001

PMCID:: PMC99970

Abstract Article PDF–521K

Select item 524237510.

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

Chrisovalantis Papadopoulos, Philipp Kirchner, Monika Bug, Daniel Grum, Lisa Koerver, Nina Schulze, Robert Poehler, Alina Dressler, Sven Fengler, Khalid Arhzaouy, Vanda Lux, Michael Ehrmann, Conrad C Weihl, Hemmo Meyer

EMBO J. 2017 Jan 17; 36(2): 135–150. Published online 2016 Oct 17. doi: 10.15252/embj.201695148

PMCID:: PMC5242375

Abstract Article PDF–10M

Select item 909846111.

Active conformation of the p97-p47 unfoldase complex

Yang Xu, Han Han, Ian Cooney, Yuxuan Guo, Noah G. Moran, Nathan R. Zuniga, John C. Price, Christopher P. Hill, Peter S. Shen

Nat Commun. 2022; 13: 2640. Published online 2022 May 12. doi: 10.1038/s41467-022-30318-3

PMCID:: PMC9098461

Abstract Article PDF–1.7M

Select item 323372712.

Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations

Xiaohong R Yang, Xueying (Sharon) Liang, Ruth M. Pfeiffer, William Wheeler, Dennis Maeder, Laurie Burdette, Meredith Yeager, Stephen Chanock, Margaret A. Tucker, Alisa M. Goldstein

Fam Cancer. Author manuscript; available in PMC 2011 Dec 8.

Published in final edited form as: Fam Cancer. 2010 Dec; 9(4): 625–633. doi: 10.1007/s10689-010-9356-3

PMCID:: PMC3233727

Abstract Article PDF–456K

Select item 542034713.

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins

Emma A. Hall, Michael S. Nahorski, Lyndsay M. Murray, Ranad Shaheen, Emma Perkins, Kosala N. Dissanayake, Yosua Kristaryanto, Ross A. Jones, Julie Vogt, Manon Rivagorda, Mark T. Handley, Girish R. Mali, Tooba Quidwai, Dinesh C. Soares, Margaret A. Keighren, Lisa McKie, Richard L. Mort, Noor Gammoh, Amaya Garcia-Munoz, Tracey Davey, Matthieu Vermeren, Diana Walsh, Peter Budd, Irene A. Aligianis, Eissa Faqeih, Alan J. Quigley, Ian J. Jackson, Yogesh Kulathu, Mandy Jackson, Richard R. Ribchester, Alex von Kriegsheim, Fowzan S. Alkuraya, C. Geoffrey Woods, Eamonn R. Maher, Pleasantine Mill

Am J Hum Genet. 2017 May 4; 100(5): 706–724. Published online 2017 Apr 13. doi: 10.1016/j.ajhg.2017.03.008

PMCID:: PMC5420347

Abstract Article PDF–4.3M

Select item 377032314.

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors

M New, H Olzscha, G Liu, O Khan, L Stimson, J McGouran, D Kerr, A Coutts, B Kessler, M Middleton, N B La Thangue

Cell Death Differ. 2013 Oct; 20(10): 1306–1316. Published online 2013 May 24. doi: 10.1038/cdd.2013.47

PMCID:: PMC3770323

Abstract Article PDF–1.9M

Select item 261466315.

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

Gabriela Alexandru, Johannes Graumann, Geoffrey T. Smith, Natalie J. Kolawa, Ruihua Fang, Raymond J. Deshaies

Cell. Author manuscript; available in PMC 2009 Mar 5.

Published in final edited form as: Cell. 2008 Sep 5; 134(5): 804–816. doi: 10.1016/j.cell.2008.06.048

PMCID:: PMC2614663

Abstract Article PDF–3.7M

Select item 962397916.

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison

J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050

PMCID:: PMC9623979

Abstract Article PDF–3.7M

Select item 603073017.

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer

Mol Cell Proteomics. 2018 Jul; 17(7): 1295–1307. Published online 2018 Mar 29. doi: 10.1074/mcp.RA117.000471

PMCID:: PMC6030730

Abstract Article PDF–3.8M

Select item 1024099818.

PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805

Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang

Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558

PMCID:: PMC10240998

Abstract Article PDF–4.4M

Select item 982313119.

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz

J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766

PMCID:: PMC9823131

Abstract Article PDF–2.5M

Select item 818479620.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

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