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Select item 54308561.

Peripheral blood AKAP7 expression as an early marker for lymphocyte-mediated post-stroke blood brain barrier disruption

Grant C. O’Connell, Madison B. Treadway, Ashley B. Petrone, Connie S. Tennant, Noelle Lucke-Wold, Paul D. Chantler, Taura L. Barr

Sci Rep. 2017; 7: 1172. Published online 2017 Apr 26. doi: 10.1038/s41598-017-01178-5

PMCID:: PMC5430856

Abstract Article PDF–2.7M

Select item 49732992.

Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state

Kaare Bjerregaard-Andersen, Ellen Østensen, John D. Scott, Kjetil Taskén, Jens Preben Morth

Acta Crystallogr F Struct Biol Commun. 2016 Aug 1; 72(Pt 8): 591–597. Published online 2016 Jul 13. doi: 10.1107/S2053230X16010189

PMCID:: PMC4973299

Abstract Article PDF–1.2M

Select item 39009783.

Scaffold State Switching Amplifies, Accelerates, and Insulates Protein Kinase C Signaling

Eric C. Greenwald, John M. Redden, Kimberly L. Dodge-Kafka, Jeffrey J. Saucerman

J Biol Chem. 2014 Jan 24; 289(4): 2353–2360. Published online 2013 Dec 3. doi: 10.1074/jbc.M113.497941

PMCID:: PMC3900978

Abstract Article PDF–1.7M

Select item 31884564.

AKAP18 contains a phosphoesterase domain which binds AMP

Matthew G. Gold, F. Donelson Smith, John D. Scott, David Barford

J Mol Biol. Author manuscript; available in PMC 2011 Oct 6.

Published in final edited form as: J Mol Biol. 2008 Feb 1; 375(5): 1329–1343. Published online 2007 Nov 22. doi: 10.1016/j.jmb.2007.11.037

PMCID:: PMC3188456

Abstract Article PDF–5.9M

Select item 21742365.

Alternative Splicing Regulates the Subcellular Localization of a-Kinase Anchoring Protein 18 Isoforms

Kevin W. Trotter, Iain D.C. Fraser, Gregory K. Scott, M. Jackson Stutts, John D. Scott, Sharon L. Milgram

J Cell Biol. 1999 Dec 27; 147(7): 1481–1492. doi: 10.1083/jcb.147.7.1481

PMCID:: PMC2174236

Abstract Article PDF–680K

Select item 11705706.

A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events.

I D Fraser, S J Tavalin, L B Lester, L K Langeberg, A M Westphal, R A Dean, N V Marrion, J D Scott

EMBO J. 1998 Apr 15; 17(8): 2261–2272. doi: 10.1093/emboj/17.8.2261

PMCID:: PMC1170570

Summary PDF–569K

Select item 1535757.

Bioinformatic design of A-kinase anchoring protein-in silico: A potent and selective peptide antagonist of type II protein kinase A anchoring

Neal M. Alto, Scott H. Soderling, Naoto Hoshi, Lorene K. Langeberg, Rosa Fayos, Patricia A. Jennings, John D. Scott

Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8): 4445–4450. Published online 2003 Apr 2. doi: 10.1073/pnas.0330734100

PMCID:: PMC153575

Abstract Article PDF–524K

Select item 50566308.

The CCND1 870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

Niels Weinhold, David C Johnson, Daniel Chubb, Bowang Chen, Asta Försti, Fay J Hosking, Peter Broderick, Yussanne P Ma, Sara E Dobbins, Dirk Hose, Brian A Walker, Faith E Davies, Martin F Kaiser, Ni L Li, Walter A Gregory, Graham H Jackson, Mathias Witzens-Harig, Kai Neben, Per Hoffmann, Markus M Nöthen, Thomas W Mühleisen, Lewin Eisele, Fiona M Ross, Anna Jauch, Hartmut Goldschmidt, Richard S Houlston, Gareth J Morgan, Kari Hemminki

Nat Genet. Author manuscript; available in PMC 2016 Oct 10.

Published in final edited form as: Nat Genet. 2013 May; 45(5): 522–525. Published online 2013 Mar 17. doi: 10.1038/ng.2583

PMCID:: PMC5056630

Abstract Article PDF–483K

Select item 53435939.

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor

Yuri Kotani, Daisuke Morito, Kenshiro Sakata, Shiori Ainuki, Munechika Sugihara, Tomohisa Hatta, Shun-ichiro Iemura, Seiji Takashima, Tohru Natsume, Kazuhiro Nagata

Sci Rep. 2017; 7: 44293. Published online 2017 Mar 9. doi: 10.1038/srep44293

PMCID:: PMC5343593

Abstract Article PDF–1.4M

Select item 449890310.

Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

Célia Jeronimo, Diane Forget, Annie Bouchard, Qintong Li, Gordon Chua, Christian Poitras, Cynthia Thérien, Dominique Bergeron, Sylvie Bourassa, Jack Greenblatt, Benoit Chabot, Guy G. Poirier, Timothy R. Hughes, Mathieu Blanchette, David H. Price, Benoit Coulombe

Mol Cell. Author manuscript; available in PMC 2015 Jul 10.

Published in final edited form as: Mol Cell. 2007 Jul 20; 27(2): 262–274. doi: 10.1016/j.molcel.2007.06.027

PMCID:: PMC4498903

Abstract Article PDF–1.5M

Select item 607772211.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 1007290612.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 271642213.

Defining the Human Deubiquitinating Enzyme Interaction Landscape

Mathew E. Sowa, Eric J. Bennett, Steven P. Gygi, J. Wade Harper

Cell. Author manuscript; available in PMC 2010 Jul 23.

Published in final edited form as: Cell. 2009 Jul 23; 138(2): 389–403. Published online 2009 Jul 16. doi: 10.1016/j.cell.2009.04.042

PMCID:: PMC2716422

Abstract Article PDF–6.1M

Select item 599939614.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Abstract Article PDF–3.6M

Select item 318838815.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Abstract Article PDF–932K

Select item 742732716.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 289646417.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 426658818.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 911973619.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 135612920.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

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