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Select item 50628471.

Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE

Li-Min Xu, Lei Chen, Feng Li, Run Zhang, Zong-yang Li, Fan-Fan Chen, Xiao-Dan Jiang

J Exp Clin Cancer Res. 2016; 35: 162. Published online 2016 Oct 12. doi: 10.1186/s13046-016-0431-y

PMCID:: PMC5062847

Abstract Article PDF–2.3M

Select item 58032022.

BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage

Kajal Biswas, Subha Philip, Aditya Yadav, Betty K. Martin, Sandra Burkett, Vaibhav Singh, Anav Babbar, Susan Lynn North, Suhwan Chang, Shyam K. Sharan

Nat Commun. 2018; 9: 537. Published online 2018 Feb 7. doi: 10.1038/s41467-018-03020-6

PMCID:: PMC5803202

Abstract Article PDF–5.0M

Select item 53865813.

BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse

Cheung Kwan Yeung, Guang Wang, Yao Yao, Jianxin Liang, Cheuk Yiu Tenny Chung, Manli Chuai, Kenneth Ka Ho Lee, Xuesong Yang

Cell Death Dis. 2017 Mar; 8(3): e2697. Published online 2017 Mar 23. doi: 10.1038/cddis.2017.91

PMCID:: PMC5386581

Abstract Article PDF–7.5M

Select item 48023294.

BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence

Wenting Shi, Mei Kuen Tang, Yao Yao, Chengcheng Tang, Yiu Loon Chui, Kenneth Ka Ho Lee

Sci Rep. 2016; 6: 23506. Published online 2016 Mar 22. doi: 10.1038/srep23506

PMCID:: PMC4802329

Abstract Article PDF–1.9M

Select item 51993395.

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex

Otto J.P. Kyrieleis, Pauline B. McIntosh, Sarah R. Webb, Lesley J. Calder, Janette Lloyd, Nisha A. Patel, Stephen R. Martin, Carol V. Robinson, Peter B. Rosenthal, Stephen J. Smerdon

Cell Rep. 2016 Dec 20; 17(12): 3099–3106. Published online 2016 Dec 22. doi: 10.1016/j.celrep.2016.11.063

PMCID:: PMC5199339

Abstract Article PDF–2.3M

Select item 28562406.

Specificity of the BRISC Deubiquitinating Enzyme Is Not Due to Selective Binding to Lys⁶³-linked Polyubiquitin

Eric M. Cooper, Jef D. Boeke, Robert E. Cohen

J Biol Chem. 2010 Apr 2; 285(14): 10344–10352. Published online 2009 Dec 23. doi: 10.1074/jbc.M109.059667

PMCID:: PMC2856240

Abstract Article PDF–2.5M

Select item 69143627.

Metabolic control of BRISC-SHMT2 assembly regulates immune signaling

Miriam Walden, Lei Tian, Rebecca Ross, Upasana M. Sykora, Dominic P. Byrne, Emma L. Hesketh, Safi K. Masandi, Joel Cassel, Rachel George, James R. Ault, Farid El Oualid, Krzysztof Pawłowski, Joseph M. Salvino, Patrick A. Eyers, Neil A. Ranson, Francesco Del Galdo, Roger A. Greenberg, Elton Zeqiraj

Nature. Author manuscript; available in PMC 2019 Dec 16.

Published in final edited form as: Nature. 2019 Jun; 570(7760): 194–199. Published online 2019 May 29. doi: 10.1038/s41586-019-1232-1

PMCID:: PMC6914362

Abstract Article PDF–5.9M

Select item 66954768.

Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation

Julius Rabl, Richard D. Bunker, Andreas D. Schenk, Simone Cavadini, Mark E. Gill, Wassim Abdulrahman, Amparo Andrés-Pons, Martijn S. Luijsterburg, Adel F.M. Ibrahim, Emma Branigan, Jacob D. Aguirre, Aimee H. Marceau, Claire Guérillon, Tewis Bouwmeester, Ulrich Hassiepen, Antoine H.F.M. Peters, Martin Renatus, Laurent Gelman, Seth M. Rubin, Niels Mailand, Haico van Attikum, Ronald T. Hay, Nicolas H. Thomä

Mol Cell. 2019 Aug 8; 75(3): 483–497.e9. doi: 10.1016/j.molcel.2019.06.002

PMCID:: PMC6695476

Abstract Article

Select item 42058869.

ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53

Jianhong Zhang, Mengmeng Cao, Jiahong Dong, Changyan Li, Wangxiang Xu, Yiqun Zhan, Xiaohui Wang, Miao Yu, Changhui Ge, Zhiqiang Ge, Xiaoming Yang

Nat Commun. 2014 Oct 6; 5: 5059. Published online 2014 Oct 6. doi: 10.1038/ncomms6059

PMCID:: PMC4205886

Abstract Article PDF–4.3M

Select item 306422510.

NBA1/MERIT40 and BRE Interaction Is Required for the Integrity of Two Distinct Deubiquitinating Enzyme BRCC36-containing Complexes

Xin Hu, Jin Ah Kim, Andy Castillo, Michael Huang, Jianxin Liu, Bin Wang

J Biol Chem. 2011 Apr 1; 286(13): 11734–11745. Published online 2011 Jan 31. doi: 10.1074/jbc.M110.200857

PMCID:: PMC3064225

Abstract Article PDF–3.7M

Select item 340815011.

Rap80 Protein Recruitment to DNA Double-strand Breaks Requires Binding to Both Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Conjugates

Xin Hu, Atanu Paul, Bin Wang

J Biol Chem. 2012 Jul 20; 287(30): 25510–25519. Published online 2012 Jun 11. doi: 10.1074/jbc.M112.374116

PMCID:: PMC3408150

Abstract Article PDF–3.1M

Select item 413168512.

RNF4-Dependent Hybrid SUMO-Ubiquitin Chains are Signals for RAP80 and thereby Mediate the Recruitment of BRCA1 to Sites of DNA Damage

Catherine M. Guzzo, Christopher E. Berndsen, Jianmei Zhu, Vibhor Gupta, Ajit Datta, Roger A. Greenberg, Cynthia Wolberger, Michael J. Matunis

Sci Signal. Author manuscript; available in PMC 2014 Aug 13.

Published in final edited form as: Sci Signal. 2012 Dec 4; 5(253): ra88. Published online 2012 Dec 4. doi: 10.1126/scisignal.2003485

PMCID:: PMC4131685

Abstract Article PDF–1.0M

Select item 869215913.

PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer

Mu Yun, Li Yingzi, Gao Jie, Liu Guanxin, Zeng Zimei, Cao Zhen, Li Zhi, Nie Yingjie, Sun Lunquan, Chen Tao, Deng Yuezhen, Zhou Chengzhi

Int J Biol Sci. 2022; 18(1): 214–228. Published online 2022 Jan 1. doi: 10.7150/ijbs.65654

PMCID:: PMC8692159

Abstract Article PDF–4.6M

Select item 450888414.

The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells

Kaowen Yan, Li Li, Xiaojian Wang, Ruisha Hong, Ying Zhang, Hua Yang, Ming Lin, Sha Zhang, Qihua He, Duo Zheng, Jun Tang, Yuxin Yin, Genze Shao

J Cell Biol. 2015 Jul 20; 210(2): 209–224. doi: 10.1083/jcb.201503039

PMCID:: PMC4508884

Abstract Article PDF–3.3M

Select item 315826115.

Tumor Suppressor Role for the SPOP Ubiquitin Ligase in Signal-Dependent Proteolysis of the Oncogenic Coactivator SRC-3/AIB1

Chao Li, Junping Ao, Junjiang Fu, Dung-Fang Lee, Jianming Xu, David Lonard, Bert W. O’Malley

Oncogene. Author manuscript; available in PMC 2012 Apr 20.

Published in final edited form as: Oncogene. 2011 Oct 20; 30(42): 4350–4364. Published online 2011 May 16. doi: 10.1038/onc.2011.151

PMCID:: PMC3158261

Abstract Article PDF–1.4M

Select item 270658316.

RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites

Bijan Sobhian, Genze Shao, Dana R. Lilli, Aedín C. Culhane, Lisa A. Moreau, Bing Xia, David M. Livingston, Roger A. Greenberg

Science. Author manuscript; available in PMC 2009 Jul 7.

Published in final edited form as: Science. 2007 May 25; 316(5828): 1198–1202. doi: 10.1126/science.1139516

PMCID:: PMC2706583

Abstract Article PDF–2.4M

Select item 266161217.

MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks

Genze Shao, Jeffrey Patterson-Fortin, Troy E. Messick, Dan Feng, Niraj Shanbhag, Yingqun Wang, Roger A. Greenberg

Genes Dev. 2009 Mar 15; 23(6): 740–754. doi: 10.1101/gad.1739609

PMCID:: PMC2661612

Abstract Article PDF–1.5M

Select item 263067218.

Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

Jiaxue Wu, Michael S. Y. Huen, Lin-Yu Lu, Lin Ye, Yali Dou, Mats Ljungman, Junjie Chen, Xiaochun Yu

Mol Cell Biol. 2009 Feb; 29(3): 849–860. Published online 2008 Nov 17. doi: 10.1128/MCB.01302-08

PMCID:: PMC2630672

Abstract Article PDF–1.9M

Select item 266603019.

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

Eric M Cooper, Colleen Cutcliffe, Troels Z Kristiansen, Akhilesh Pandey, Cecile M Pickart, Robert E Cohen

EMBO J. 2009 Mar 18; 28(6): 621–631. Published online 2009 Feb 12. doi: 10.1038/emboj.2009.27

PMCID:: PMC2666030

Abstract Article PDF–253K

Select item 645043020.

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination

Ryan Donaghy, Xu Han, Krasimira Rozenova, Kaosheng Lv, Qinqin Jiang, Miriam Doepner, Roger A. Greenberg, Wei Tong

Blood. 2019 Apr 4; 133(14): 1560–1571. Prepublished online 2019 Feb 12. doi: 10.1182/blood-2018-10-877563

PMCID:: PMC6450430

Abstract Article

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