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Select item 92469171.

Breast cancer patient-derived organoid screening implicates the repressor NCOR2 in cytotoxic stress response and anti-tumor immunity

Kelvin K. Tsai, Shenq-Shyang Huang, Jason J. Northey, Wen-Ying Liao, Chung-Chi Hsu, Li-Hsin Cheng, Michael E. Werner, Chih-Pin Chuu, Chandrima Chatterjee, Jonathan N. Lakins, Valerie M. Weaver

Nat Cancer. Author manuscript; available in PMC 2022 Nov 26.

Published in final edited form as: Nat Cancer. 2022 Jun; 3(6): 734–752. Published online 2022 May 26. doi: 10.1038/s43018-022-00375-0

PMCID:: PMC9246917

Abstract Article PDF–6.8M

Select item 88896232.

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

Mark D. Long, Justine J. Jacobi, Prashant K. Singh, Gerard Llimos, Sajad A. Wani, Aryn M. Rowsam, Spencer R. Rosario, Marlous Hoogstraat, Simon Linder, Jason Kirk, Hayley C. Affronti, Andries Bergman, Wilbert Zwart, Moray J. Campbell, Dominic J. Smiraglia

Cell Rep. Author manuscript; available in PMC 2022 Mar 2.

Published in final edited form as: Cell Rep. 2021 Dec 14; 37(11): 110109. doi: 10.1016/j.celrep.2021.110109

PMCID:: PMC8889623

Abstract Article PDF–3.2M

Select item 75030313.

Circular RNA circ-NCOR2 accelerates papillary thyroid cancer progression by sponging miR-516a-5p to upregulate metastasis-associated protein 2 expression

Sha Luan, Peng Fu, Xinyu Wang, Yue Gao, Ke Shi, Youmin Guo

J Int Med Res. 2020 Sep; 48(9): 0300060520934659. Published online 2020 Sep 17. doi: 10.1177/0300060520934659

PMCID:: PMC7503031

Abstract Article PDF–1.1M

Select item 60389154.

BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen Resistant Breast Cancer

Chun Gong, Ellen PS Man, Ho Tsoi, Terence KW Lee, Lee Paul, Sai-Ting Mak, Lai-San Wong, Mai-Yee Luk, Emad A. Rakha, Andrew R Green, Ian O Ellis, Eric W-F Lam, Kwok-Leung Cheung, Ui-Soon Khoo

Clin Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Clin Cancer Res. 2018 Aug 1; 24(15): 3681–3691. Published online 2018 Feb 2. doi: 10.1158/1078-0432.CCR-17-2259

PMCID:: PMC6038915

Abstract Article PDF–1.4M

Select item 47376185.

Association of Forced Vital Capacity with the Developmental Gene NCOR2

Cosetta Minelli, Charlotte H. Dean, Matthew Hind, Alexessander Couto Alves, André F. S. Amaral, Valerie Siroux, Ville Huikari, María Soler Artigas, David M. Evans, Daan W. Loth, Yohan Bossé, Dirkje S. Postma, Don Sin, John Thompson, Florence Demenais, John Henderson, SpiroMeta consortium, CHARGE consortium, Emmanuelle Bouzigon, Deborah Jarvis, Marjo-Riitta Järvelin, Peter Burney

PLoS One. 2016; 11(2): e0147388. Published online 2016 Feb 2. doi: 10.1371/journal.pone.0147388

PMCID:: PMC4737618

Abstract Article PDF–284K

Select item 45050666.

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Gregg M. Hudson, Peter J. Watson, Louise Fairall, Andrew G. Jamieson, John W. R. Schwabe

J Biol Chem. 2015 Jul 17; 290(29): 18237–18244. Published online 2015 Jun 8. doi: 10.1074/jbc.M115.661058

PMCID:: PMC4505066

Abstract Article PDF–1.6M

Select item 35117727.

Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence

Carolyn L. Smith, Ilenia Migliaccio, Vaishali Chaubal, Meng-Fen Wu, Margaret C. Pace, Ryan Hartmaier, Shiming Jiang, Dean P. Edwards, M. Carolina Gutiérrez, Susan G. Hilsenbeck, Steffi Oesterreich

Breast Cancer Res Treat. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Breast Cancer Res Treat. 2012 Nov; 136(1): 253–265. Published online 2012 Sep 27. doi: 10.1007/s10549-012-2262-7

PMCID:: PMC3511772

Abstract Article PDF–1.3M

Select item 34690538.

Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL

H-C Chi, S-L Chen, C-J Liao, C-H Liao, M-M Tsai, Y-H Lin, Y-H Huang, C-T Yeh, S-M Wu, Y-H Tseng, C-Y Chen, C-Y Tsai, I-H Chung, W-J Chen, K-H Lin

Cell Death Differ. 2012 Nov; 19(11): 1802–1814. Published online 2012 May 11. doi: 10.1038/cdd.2012.58

PMCID:: PMC3469053

Abstract Article PDF–1.2M

Select item 88650479.

Recurrent Fusion of the Genes for High-mobility Group AT-hook 2 (HMGA2) and Nuclear Receptor Co-repressor 2 (NCOR2) in Osteoclastic Giant Cell-rich Tumors of Bone

IOANNIS PANAGOPOULOS, KRISTIN ANDERSEN, LUDMILA GORUNOVA, MARIUS LUND-IVERSEN, INGVILD LOBMAIER, SVERRE HEIM

Cancer Genomics Proteomics. 2022 Mar-Apr; 19(2): 163–177. Published online 2022 Mar 3. doi: 10.21873/cgp.20312

PMCID:: PMC8865047

Abstract Article PDF–5.1M

Select item 864335410.

Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation

Tomoaki Mori, Rakesh Verma, Rie Nakamoto-Matsubara, Ka Tat Siu, Cristina Panaroni, Keertik S. Fulzele, Kenta Mukaihara, Chukwuamaka Onyewadume, Allison Maebius, Hiroki Kato, Lai Ping Wong, Ruslan I. Sadreyev, David T. Scadden, Noopur S. Raje

Blood Cancer J. 2021 Dec; 11(12): 194. Published online 2021 Dec 4. doi: 10.1038/s41408-021-00589-y

PMCID:: PMC8643354

Abstract Article PDF–1.0M

Select item 850663311.

KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer

Ho Tsoi, Ellen PS Man, Man‐Hong Leung, Ka‐Chun Mok, Ka‐Man Chau, Lai‐San Wong, Wing‐Lok Chan, Sum‐Yin Chan, Mai‐Yee Luk, Cheuk‐Nam Cheng, Ui‐Soon Khoo

Clin Transl Med. 2021 Oct; 11(10): e554. Published online 2021 Oct 12. doi: 10.1002/ctm2.554

PMCID:: PMC8506633

Article PDF–3.1M

Select item 829503612.

Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors

Abbas Agaimy, Michael Michal, Robert Stoehr, Fulvia Ferrazzi, Pavel Fabian, Michal Michal, Alessandro Franchi, Florian Haller, Andrew L. Folpe, Kemal Kösemehmetoğlu

Mod Pathol. 2021; 34(8): 1507–1520. Published online 2021 Mar 19. doi: 10.1038/s41379-021-00789-8

PMCID:: PMC8295036

Abstract Article PDF–5.7M

Select item 724934713.

Ubiquitin ligase CHAF1B induces cisplatin resistance in lung adenocarcinoma by promoting NCOR2 degradation

Lian Gong, Yi Hu, Dong He, Yuxing Zhu, Liang Xiang, Mengqing Xiao, Ying Bao, Xiaoming Liu, Qinghai Zeng, Jianye Liu, Ming Zhou, Yanhong Zhou, Yaxin Cheng, Yeyu Zhang, Liping Deng, Rongrong Zhu, Hua Lan, Ke Cao

Cancer Cell Int. 2020; 20: 194. Published online 2020 May 25. doi: 10.1186/s12935-020-01263-2

PMCID:: PMC7249347

Abstract Article PDF–2.3M

Select item 658047614.

Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals

Martin L. Privalsky, Michael L. Goodson

BMC Res Notes. 2019; 12: 343. Published online 2019 Jun 17. doi: 10.1186/s13104-019-4384-z

PMCID:: PMC6580476

Abstract Article PDF–1.1M

Select item 646055915.

TBL1Y: a new gene involved in syndromic hearing loss

Mariateresa Di Stazio, Chiara Collesi, Diego Vozzi, Wei Liu, Mike Myers, Anna Morgan, Pio Adamo D′Adamo, Giorgia Girotto, Elisa Rubinato, Mauro Giacca, Paolo Gasparini

Eur J Hum Genet. 2019 Mar; 27(3): 466–474. Published online 2018 Oct 19. doi: 10.1038/s41431-018-0282-4

PMCID:: PMC6460559

Abstract Article PDF–2.3M

Select item 629451516.

Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4

Suk-Youl Park, Gwang Sik Kim, Hyo-Jeong Hwang, Taek-Hyun Nam, Hee-Sae Park, Jaeyoung Song, Tae-Ho Jang, Young Chul Lee, Jeong-Sun Kim

Nucleic Acids Res. 2018 Dec 14; 46(22): 11776–11788. Published online 2018 Oct 13. doi: 10.1093/nar/gky926

PMCID:: PMC6294515

Abstract Article PDF–3.0M

Select item 618222017.

OPTHiS Identifies the Molecular Basis of the Direct Interaction between CSL and SMRT Corepressor

Gwang Sik Kim, Hee-Sae Park, Young Chul Lee

Mol Cells. 2018 Sep 30; 41(9): 842–852. Published online 2018 Aug 30. doi: 10.14348/molcells.2018.0196

PMCID:: PMC6182220

Abstract Article PDF–2.0M

Select item 582344918.

The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma

Juan Pablo Rigalli, Matthias Reichel, Tasmin Reuter, Guillermo Nicolás Tocchetti, Gerhard Dyckhoff, Christel Herold-Mende, Dirk Theile, Johanna Weiss

PLoS One. 2018; 13(2): e0193242. Published online 2018 Feb 22. doi: 10.1371/journal.pone.0193242

PMCID:: PMC5823449

Abstract Article PDF–6.3M

Select item 577217219.

Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2

Jil Sander, Susanne V. Schmidt, Branko Cirovic, Naomi McGovern, Olympia Papantonopoulou, Anna-Lena Hardt, Anna C. Aschenbrenner, Christoph Kreer, Thomas Quast, Alexander M. Xu, Lisa M. Schmidleithner, Heidi Theis, Lan Do Thi Huong, Hermi Rizal Bin Sumatoh, Mario A.R. Lauterbach, Jonas Schulte-Schrepping, Patrick Günther, Jia Xue, Kevin Baßler, Thomas Ulas, Kathrin Klee, Natalie Katzmarski, Stefanie Herresthal, Wolfgang Krebs, Bianca Martin, Eicke Latz, Kristian Händler, Michael Kraut, Waldemar Kolanus, Marc Beyer, Christine S. Falk, Bettina Wiegmann, Sven Burgdorf, Nicholas A. Melosh, Evan W. Newell, Florent Ginhoux, Andreas Schlitzer, Joachim L. Schultze

Immunity. 2017 Dec 19; 47(6): 1051–1066.e12. doi: 10.1016/j.immuni.2017.11.024

PMCID:: PMC5772172

Abstract Article

Select item 450126920.

Rifampicin-Independent Interactions between the Pregnane X Receptor Ligand Binding Domain and Peptide Fragments of Coactivator and Corepressor Proteins

Punya Navaratnarajah, Bridgett L. Steele, Matthew R. Redinbo, Nancy L. Thompson

Biochemistry. Author manuscript; available in PMC 2015 Jul 14.

Published in final edited form as: Biochemistry. 2012 Jan 10; 51(1): 19–31. Published online 2011 Dec 20. doi: 10.1021/bi2011674

PMCID:: PMC4501269

Abstract Article PDF–818K

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