PMC Links for Gene (Select 9627) - PMC

Xueping Li, Yada Treesukosol, Alexander Moghadam, Megan Smith, Erica Ofeldt, Dejun Yang, Tianxia Li, Kellie Tamashiro, Pique Choi, Timothy H. Moran, Wanli W. Smith

PLoS One. 2014; 9(5): e91449. Published online 2014 May 14. doi: 10.1371/journal.pone.0091449

PMCID:: PMC4020742

Abstract Article PDF–875K

Select item 67249828.

α-Synuclein Phosphorylation Enhances Eosinophilic Cytoplasmic Inclusion Formation in SH-SY5Y Cells

Wanli W. Smith, Russell L. Margolis, Xiaojie Li, Juan C. Troncoso, Michael K. Lee, Valina L. Dawson, Ted M. Dawson, Takashi Iwatsubo, Christopher A. Ross

J Neurosci. 2005 Jun 8; 25(23): 5544–5552. doi: 10.1523/JNEUROSCI.0482-05.2005

PMCID:: PMC6724982

Abstract Article PDF–606K

Select item 42271489.

GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein

S Bellani, A Mescola, G Ronzitti, H Tsushima, S Tilve, C Canale, F Valtorta, E Chieregatti

Cell Death Differ. 2014 Dec; 21(12): 1971–1983. Published online 2014 Aug 15. doi: 10.1038/cdd.2014.111

PMCID:: PMC4227148

Abstract Article PDF–4.1M

Select item 355232610.

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity

Thai Leong Yap, Arash Velayati, Ellen Sidransky, Jennifer C. Lee

Mol Genet Metab. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Mol Genet Metab. 2013 Jan; 108(1): 56–64. Published online 2012 Nov 28. doi: 10.1016/j.ymgme.2012.11.010

PMCID:: PMC3552326

Abstract Article PDF–1.7M

Select item 145867311.

Synphilin-1A: An aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from α-synucleinopathy patients

Allon Eyal, Raymonde Szargel, Eyal Avraham, Esti Liani, Joseph Haskin, Ruth Rott, Simone Engelender

Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15): 5917–5922. Published online 2006 Apr 4. doi: 10.1073/pnas.0509707103

PMCID:: PMC1458673

Abstract Article PDF–2.4M

Select item 672606912.

Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation

Kah Leong Lim, Katherine C. M. Chew, Jeanne M. M. Tan, Cheng Wang, Kenny K. K. Chung, Yi Zhang, Yuji Tanaka, Wanli Smith, Simone Engelender, Christopher A. Ross, Valina L. Dawson, Ted M. Dawson

J Neurosci. 2005 Feb 23; 25(8): 2002–2009. doi: 10.1523/JNEUROSCI.4474-04.2005

PMCID:: PMC6726069

Abstract Article PDF–360K

Select item 450276013.

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment

Anne-Maria Poehler, Wei Xiang, Philipp Spitzer, Verena Elisabeth Luise May, Holger Meixner, Edward Rockenstein, Oldriska Chutna, Tiago Fleming Outeiro, Juergen Winkler, Eliezer Masliah, Jochen Klucken

Autophagy. 2014 Dec; 10(12): 2171–2192. Published online 2015 Jan 28. doi: 10.4161/auto.36436

PMCID:: PMC4502760

Abstract Article PDF–2.9M

Select item 445992114.

α-Synuclein binds the K_ATP channel at insulin-secretory granules and inhibits insulin secretion

Xuehui Geng, Haiyan Lou, Jian Wang, Lehong Li, Alexandra L. Swanson, Ming Sun, Donna Beers-Stolz, Simon Watkins, Ruth G. Perez, Peter Drain

Am J Physiol Endocrinol Metab. 2011 Feb; 300(2): E276–E286. Published online 2010 Sep 21. doi: 10.1152/ajpendo.00262.2010

PMCID:: PMC4459921

Abstract Article

Select item 444796115.

Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling

Kristi L. Norris, Rui Hao, Liang-Fu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J. Shaughnessy, Dennis Chou, Jin Yan, J. Paul Taylor, Simone Engelender, Anna E. West, Kah-Leong Lim, Tso-Pang Yao

J Biol Chem. 2015 May 29; 290(22): 13862–13874. Published online 2015 Apr 10. doi: 10.1074/jbc.M114.634063

PMCID:: PMC4447961

Abstract Article PDF–4.3M

Select item 371508616.

Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model

J Liu, T Li, D Yang, R Ma, TH Moran, WW Smith

Int J Obes (Lond) Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Int J Obes (Lond). 2012 Dec; 36(12): 1529–1536. Published online 2012 Jul 17. doi: 10.1038/ijo.2012.111

Correction in:: volume 36 on page 1592

PMCID:: PMC3715086

Abstract Article PDF–2.9M

Select item 352739117.

The Guanine Nucleotide Exchange Factor Kalirin-7 Is a Novel Synphilin-1 Interacting Protein and Modifies Synphilin-1 Aggregate Transport and Formation

Yu-Chun Tsai, Olaf Riess, Anne S. Soehn, Huu Phuc Nguyen

PLoS One. 2012; 7(12): e51999. Published online 2012 Dec 20. doi: 10.1371/journal.pone.0051999

PMCID:: PMC3527391

Abstract Article PDF–5.8M

Select item 169879218.

NUB1 Suppresses the Formation of Lewy Body-Like Inclusions by Proteasomal Degradation of Synphilin-1

Kunikazu Tanji, Tomoaki Tanaka, Fumiaki Mori, Katsumi Kito, Hitoshi Takahashi, Koichi Wakabayashi, Tetsu Kamitani

Am J Pathol. 2006 Aug; 169(2): 553–565. doi: 10.2353/ajpath.2006.051067

PMCID:: PMC1698792

Abstract Article PDF–2.3M

Select item 290824719.

IDENTIFICATION AND CHARACTERIZATION OF A NOVEL ENDOGENOUS MURINE PARKIN MUTATION

Chenere P. Ramsey, Benoit I. Giasson

J Neurochem. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: J Neurochem. 2010 Apr; 113(2): 402–417. Published online 2010 Jan 20. doi: 10.1111/j.1471-4159.2010.06605.x

PMCID:: PMC2908247

Abstract Article PDF–2.3M

Select item 39741220.

Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

Esti Liani, Allon Eyal, Eyal Avraham, Revital Shemer, Raymonde Szargel, Daniela Berg, Antje Bornemann, Olaf Riess, Christopher A. Ross, Ruth Rott, Simone Engelender

Proc Natl Acad Sci U S A. 2004 Apr 13; 101(15): 5500–5505. Published online 2004 Apr 2. doi: 10.1073/pnas.0401081101