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Select item 88944871.

Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli

Jae Hee Jun, Eun Ji Lee, Minah Park, Je Yeong Ko, Jong Hoon Park

Exp Mol Med. 2022 Feb; 54(2): 169–179. Published online 2022 Feb 17. doi: 10.1038/s12276-022-00730-2

PMCID:: PMC8894487

Article PDF–6.8M

Select item 88142032.

TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A

Jun-Ha Hwang, Kyung Min Kim, Ho Taek Oh, Gi Don Yoo, Mi Gyeong Jeong, Hyun Lee, Joori Park, Kwon Jeong, Yoon Ki Kim, Young-Gyu Ko, Eun Sook Hwang, Jeong-Ho Hong

Nat Commun. 2022; 13: 653. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28247-2

PMCID:: PMC8814203

Article PDF–1.8M

Select item 66755543.

TAZ is required for lung alveolar epithelial cell differentiation after injury

Tianhe Sun, Zhiyu Huang, Hua Zhang, Clara Posner, Guiquan Jia, Thirumalai R. Ramalingam, Min Xu, Hans Brightbill, Jackson G. Egen, Anwesha Dey, Joseph R. Arron

JCI Insight. 2019 Jul 25; 4(14): e128674. Published online 2019 Jul 25. doi: 10.1172/jci.insight.128674

PMCID:: PMC6675554

Article PDF–52M

Select item 59013804.

Deregulation of Hippo–TAZ pathway during renal injury confers a fibrotic maladaptive phenotype

Sandybell Anorga, Jessica M. Overstreet, Lucas L. Falke, Jiaqi Tang, Roel G. Goldschmeding, Paul J. Higgins, Rohan Samarakoon

FASEB J. 2018 May; 32(5): 2644–2657. Published online 2018 Jan 8. doi: 10.1096/fj.201700722R

PMCID:: PMC5901380

Article

Select item 39935945.

Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model

Zeyu Yang, Kentaro Nakagawa, Aradhan Sarkar, Junichi Maruyama, Hiroaki Iwasa, Yijun Bao, Mari Ishigami-Yuasa, Shigeru Ito, Hiroyuki Kagechika, Shoji Hata, Hiroshi Nishina, Shinya Abe, Masanobu Kitagawa, Yutaka Hata

Mol Cell Biol. 2014 May; 34(9): 1607–1621. doi: 10.1128/MCB.01346-13

PMCID:: PMC3993594

Article PDF–4.4M

Select item 33727396.

TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

EJ Jang, H Jeong, JO Kang, NJ Kim, MS Kim, SH Choi, SE Yoo, JH Hong, MA Bae, ES Hwang

Br J Pharmacol. 2012 Mar; 165(5): 1584–1594. doi: 10.1111/j.1476-5381.2011.01664.x

PMCID:: PMC3372739

Article PDF–1.4M

Select item 110773757.

TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction

Hyo Kyeong Kim, Hana Jeong, Mi Gyeong Jeong, Hee Yeon Won, Gibbeum Lee, Soo Han Bae, Miso Nam, Sung Hoon Lee, Geum-Sook Hwang, Eun Sook Hwang

Int J Biol Sci. 2024; 20(7): 2592–2606. Published online 2024 Apr 22. doi: 10.7150/ijbs.88897

PMCID:: PMC11077375

Article PDF–9.3M

Select item 108102238.

The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromuscular junctions in skeletal muscle fibers

Lea Gessler, Danyil Huraskin, Yongzhi Jian, Nane Eiber, Zhaoyong Hu, Tomasz J Prószyński, Said Hashemolhosseini

Nucleic Acids Res. 2024 Jan 25; 52(2): 600–624. Published online 2023 Dec 4. doi: 10.1093/nar/gkad1124

PMCID:: PMC10810223

Article PDF–3.7M

Select item 107897919.

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury

Ari Kwon, Na Young Lee, Jae-Hyun Yu, Myeung Gi Choi, Jeongwoo Park, Ja Hyun Koo

Cell Death Dis. 2024 Jan; 15(1): 51. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06448-5

PMCID:: PMC10789791

Article PDF–6.2M

Select item 1060311210.

Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice

Zhousheng Xiao, Li Cao, Micholas Dean Smith, Hanxuan Li, Wei Li, Jeremy C. Smith, Leigh Darryl Quarles

Bone Res. 2023; 11: 57. Published online 2023 Oct 26. doi: 10.1038/s41413-023-00295-4

PMCID:: PMC10603112

Article PDF–2.4M

Select item 1050438311.

Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries

Melody Devos, Joana Dias Nunes, Nathalie Donfack Jiatsa, Isabelle Demeestere

Sci Rep. 2023; 13: 15346. Published online 2023 Sep 15. doi: 10.1038/s41598-023-41954-0

PMCID:: PMC10504383

Article PDF–3.0M

Select item 1029014312.

The role of mechano-regulated YAP/TAZ in erectile dysfunction

Mintao Ji, Dongsheng Chen, Yinyin Shu, Shuai Dong, Zhisen Zhang, Haimeng Zheng, Xiaoni Jin, Lijun Zheng, Yang Liu, Yifei Zheng, Wensheng Zhang, Shiyou Wang, Guangming Zhou, Bingyan Li, Baohua Ji, Yong Yang, Yongde Xu, Lei Chang

Nat Commun. 2023; 14: 3758. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39009-z

PMCID:: PMC10290143

Article PDF–7.2M

Select item 1013232113.

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

Brian C. Leonard, Sangwan Park, Soohyun Kim, Laura J. Young, Iman Jalilian, Krista Cosert, Xunzhi Zhang, Jessica M. Skeie, Hanna Shevalye, Nayeli Echeverria, Vanessa Rozo, Xin Gong, Chao Xing, Christopher J. Murphy, Mark A. Greiner, V. Vinod Mootha, Vijay Krishna Raghunathan, Sara M. Thomasy

Invest Ophthalmol Vis Sci. 2023 Apr; 64(4): 22. Published online 2023 Apr 19. doi: 10.1167/iovs.64.4.22

PMCID:: PMC10132321

Article PDF–1.5M

Select item 1005979214.

Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors

Felipe S. Gallardo, Adriana Córdova-Casanova, Alexia Bock-Pereda, Daniela L. Rebolledo, Andrea Ravasio, Juan Carlos Casar, Enrique Brandan

Int J Mol Sci. 2023 Mar; 24(6): 5585. Published online 2023 Mar 15. doi: 10.3390/ijms24065585

PMCID:: PMC10059792

Article PDF–3.2M

Select item 966330715.

Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism

He Shen, Yuwen Zhang, Elliot D. Kramer, Eriko Katsuta, Yin Wan, Yanmin Chen, Jianmin Wang, Yali Zhang, Junko Matsuzaki, Costa Frangou, Scott I. Abrams, Jianmin Zhang

Cancer Gene Ther. 2022; 29(11): 1791–1800. Published online 2022 Jul 15. doi: 10.1038/s41417-022-00502-0

PMCID:: PMC9663307

Article PDF–2.5M

Select item 946247316.

SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models

Ryan D. Watkins, EeeLN H. Buckarma, Jennifer L. Tomlinson, Chantal E. McCabe, Jennifer A. Yonkus, Nathan W. Werneburg, Rachel L. Bayer, Patrick P. Starlinger, Keith D. Robertson, Chen Wang, Gregory J. Gores, Rory L. Smoot

JCI Insight. 2022 Aug 8; 7(15): e159930. Published online 2022 Aug 8. doi: 10.1172/jci.insight.159930

PMCID:: PMC9462473

Article PDF–12M

Select item 916452817.

The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease

Antonio Cigliano, Shanshan Zhang, Silvia Ribback, Sara Steinmann, Marcella Sini, Cindy E. Ament, Kirsten Utpatel, Xinhua Song, Jingxiao Wang, Maria G. Pilo, Fabian Berger, Haichuan Wang, Junyan Tao, Xiaolei Li, Giovanni M. Pes, Serena Mancarella, Gianluigi Giannelli, Frank Dombrowski, Matthias Evert, Diego F. Calvisi, Xin Chen, Katja Evert

J Exp Clin Cancer Res. 2022; 41: 192. Published online 2022 Jun 3. doi: 10.1186/s13046-022-02394-2

Correction in:: J Exp Clin Cancer Res. 2023; 42: 124.

PMCID:: PMC9164528

Article PDF–11M

Select item 913524718.

Regulation of myoepithelial differentiation

Renee F. Thiemann, Scott Varney, Nicholas Moskwa, John Lamar, Melinda Larsen, Susan E. LaFlamme

PLoS One. 2022; 17(5): e0268668. Published online 2022 May 26. doi: 10.1371/journal.pone.0268668

PMCID:: PMC9135247

Article PDF–2.8M

Select item 893970819.

YAP and TAZ in Vascular Smooth Muscle Confer Protection Against Hypertensive Vasculopathy

Fatima Daoud, Marycarmen Arévalo Martinez, Johan Holmberg, Azra Alajbegovic, Neserin Ali, Catarina Rippe, Karl Swärd, Sebastian Albinsson

Arterioscler Thromb Vasc Biol. 2022 Apr; 42(4): 428–443. Published online 2022 Feb 24. doi: 10.1161/ATVBAHA.121.317365

PMCID:: PMC8939708

Article PDF–1.9M

Select item 893425820.

TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis

Xiaobo Wang, Sharon Zeldin, Hongxue Shi, Changyu Zhu, Yoshinobu Saito, Kathleen E. Corey, Stephanie A. Osganian, Helen E. Remotti, Elizabeth C. Verna, Utpal B. Pajvani, Robert F. Schwabe, Ira Tabas

J Hepatol. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: J Hepatol. 2022 Apr; 76(4): 910–920. Published online 2021 Dec 11. doi: 10.1016/j.jhep.2021.11.031

PMCID:: PMC8934258

Article PDF–2.6M

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