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Select item 111451411.

MFN2 suppresses the accumulation of lipid droplets and the progression of clear cell renal cell carcinoma

Zhiduan Cai, Wenjun Luo, Haoran Wang, Rui Zhu, Yaoji Yuan, Xiangyu Zhan, Mengyuan Xie, Haoquan Zhuang, Haoyu Chen, Yuyu Xu, Xiezhao Li, Leyuan Liu, Guibin Xu

Cancer Sci. 2024 Jun; 115(6): 1791–1807. Published online 2024 Mar 13. doi: 10.1111/cas.16151

PMCID:: PMC11145141

Abstract Article PDF–36M

Select item 110583602.

Mitofusin-2 enhances cervical cancer progression through Wnt/β-catenin signaling

Sung Yong Ahn

BMB Rep. 2024 Apr 30; 57(4): 194–199. Published online 2024 Mar 21. doi: 10.5483/BMBRep.2023-0205

PMCID:: PMC11058360

Abstract Article PDF–4.5M

Select item 107341943.

Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation

Hideki Hayashi, Rie Saito, Hidetomo Tanaka, Norikazu Hara, Shin Koide, Yosuke Yonemochi, Tetsuo Ozawa, Mariko Hokari, Yasuko Toyoshima, Akinori Miyashita, Osamu Onodera, Kouichirou Okamoto, Takeshi Ikeuchi, Takashi Nakajima, Akiyoshi Kakita

Acta Neuropathol Commun. 2023; 11: 207. Published online 2023 Dec 20. doi: 10.1186/s40478-023-01692-w

PMCID:: PMC10734194

Article PDF–1.6M

Select item 102403484.

MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4

Jingjing Zhang, Lifang Pan, Qiang Zhang, Yanyan Zhao, Wenwen Wang, Nengming Lin, Shirong Zhang, Qiong Wu

FEBS Open Bio. 2023 Jun; 13(6): 1107–1124. Published online 2023 Mar 14. doi: 10.1002/2211-5463.13591

PMCID:: PMC10240348

Abstract Article PDF–4.8M

Select item 96737215.

Disruption of Sarcoplasmic Reticulum‐Mitochondrial Contacts Underlies Contractile Dysfunction in Experimental and Human Atrial Fibrillation: A Key Role of Mitofusin 2

Jin Li, Xi Qi, Kennedy S. Ramos, Eva Lanters, Jaap Keijer, Natasja de Groot, Bianca Brundel, Deli Zhang

J Am Heart Assoc. 2022 Oct 4; 11(19): e024478. Published online 2022 Sep 29. doi: 10.1161/JAHA.121.024478

PMCID:: PMC9673721

Abstract Article PDF–4.1M

Select item 90080126.

Clinical and genetic features of a cohort of patients with MFN2-related neuropathy

Elena Abati, Arianna Manini, Daniele Velardo, Roberto Del Bo, Laura Napoli, Federica Rizzo, Maurizio Moggio, Nereo Bresolin, Emilia Bellone, Maria Teresa Bassi, Maria Grazia D’Angelo, Giacomo Pietro Comi, Stefania Corti

Sci Rep. 2022; 12: 6181. Published online 2022 Apr 13. doi: 10.1038/s41598-022-10220-0

PMCID:: PMC9008012

Abstract Article PDF–1.5M

Select item 90065757.

MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway

Lidi Deng, Siqi Yi, Xiaohui Yin, Yang Li, Qingxian Luan

Stem Cell Res Ther. 2022; 13: 162. Published online 2022 Apr 12. doi: 10.1186/s13287-022-02836-w

PMCID:: PMC9006575

Abstract Article PDF–13M

Select item 87864808.

Mitofusin-2 Restrains Hepatic Stellate Cells' Proliferation via PI3K/Akt Signaling Pathway and Inhibits Liver Fibrosis in Rats

Zhiping Chen, Zeyu Lin, Jiandong Yu, Haifeng Zhong, Xianhua Zhuo, Changku Jia, Yunle Wan

J Healthc Eng. 2022; 2022: 6731335. Published online 2022 Jan 17. doi: 10.1155/2022/6731335

PMCID:: PMC8786480

Abstract Article PDF–4.4M

Select item 83974149.

Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages

Vera Khodzhaeva, Yannick Schreiber, Gerd Geisslinger, Ralf P. Brandes, Bernhard Brüne, Dmitry Namgaladze

Front Immunol. 2021; 12: 723683. Published online 2021 Aug 12. doi: 10.3389/fimmu.2021.723683

PMCID:: PMC8397414

Abstract Article PDF–3.7M

Select item 789760010.

Mitochondrial fusion protein 2 regulates endoplasmic reticulum stress in preeclampsia

Dandan SUN, Hui ZHU, Ling AI, Hanbing WU, Yanting WU, Jihua JIN

J Zhejiang Univ Sci B. 2021 Feb 15; 22(2): 165–170. doi: 10.1631/jzus.B2000557

PMCID:: PMC7897600

Abstract Article PDF–1.2M

Select item 782773811.

Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo

Fanpeng Zhao, Quillan Austria, Wenzhang Wang, Xiongwei Zhu

Int J Mol Sci. 2021 Jan; 22(2): 601. Published online 2021 Jan 9. doi: 10.3390/ijms22020601

PMCID:: PMC7827738

Abstract Article PDF–3.1M

Select item 682078812.

Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset

Yu-Jie Li, Yu-Lu Cao, Jian-Xiong Feng, Yuanbo Qi, Shuxia Meng, Jie-Feng Yang, Ya-Ting Zhong, Sisi Kang, Xiaoxue Chen, Lan Lan, Li Luo, Bing Yu, Shoudeng Chen, David C. Chan, Junjie Hu, Song Gao

Nat Commun. 2019; 10: 4914. Published online 2019 Oct 29. doi: 10.1038/s41467-019-12912-0

PMCID:: PMC6820788

Abstract Article PDF–5.1M

Select item 667207713.

Altered Axonal Mitochondrial Transport in the Pathogenesis of Charcot-Marie-Tooth Disease from Mitofusin 2 Mutations

Robert H. Baloh, Robert E. Schmidt, Alan Pestronk, Jeffrey Milbrandt

J Neurosci. 2007 Jan 10; 27(2): 422–430. doi: 10.1523/JNEUROSCI.4798-06.2007

PMCID:: PMC6672077

Abstract Article PDF–605K

Select item 652207314.

MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

Delfina Larrea, Marta Pera, Adriano Gonnelli, Rubén Quintana–Cabrera, H Orhan Akman, Cristina Guardia-Laguarta, Kevin R Velasco, Estela Area-Gomez, Federica Dal Bello, Diego De Stefani, Rita Horvath, Michael E Shy, Eric A Schon, Marta Giacomello

Hum Mol Genet. 2019 Jun 1; 28(11): 1782–1800. Published online 2019 Jan 11. doi: 10.1093/hmg/ddz008