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Select item 69328181.

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains

Dongju Park, Reena Shakya, Christopher Koivisto, Jason R. Pitarresi, Matthias Szabolcs, Raleigh Kladney, Ashley Hadjis, Thomas A. Mace, Thomas Ludwig

PLoS One. 2019; 14(12): e0226714. Published online 2019 Dec 26. doi: 10.1371/journal.pone.0226714

PMCID:: PMC6932818

Article PDF–4.3M

Select item 67078152.

Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis

Max D. Wellenstein, Seth B. Coffelt, Danique E.M. Duits, Martine H. van Miltenburg, Maarten Slagter, Iris de Rink, Linda Henneman, Sjors M. Kas, Stefan Prekovic, Cheei-Sing Hau, Kim Vrijland, Anne Paulien Drenth, Renske de Korte-Grimmerink, Eva Schut, Ingrid van der Heijden, Wilbert Zwart, Lodewyk F.A. Wessels, Ton N. Schumacher, Jos Jonkers, Karin E. de Visser

Nature. Author manuscript; available in PMC 2020 Jan 31.

Published in final edited form as: Nature. 2019 Jul 3; 572(7770): 538–542. Published online 2019 Jul 31. doi: 10.1038/s41586-019-1450-6

PMCID:: PMC6707815

Article PDF–5.7M

Select item 66939123.

The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice

Miao Li, Tao Huang, Meng-Jing Li, Chuan-Xin Zhang, Xiao-Chen Yu, Ying-Ying Yin, Chao Liu, Xin Wang, Hai-Wei Feng, Tuo Zhang, Mo-Fang Liu, Chun-Sheng Han, Gang Lu, Wei Li, Jin-Long Ma, Zi-Jiang Chen, Hong-Bin Liu, Kui Liu

Sci Adv. 2019 Aug; 5(8): eaax1101. Published online 2019 Aug 14. doi: 10.1126/sciadv.aax1101

PMCID:: PMC6693912

Article PDF–15M

Select item 63984474.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Article

Select item 56663185.

Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing

H Huskova, M Ardin, A Weninger, K Vargova, S Barrin, S Villar, M Olivier, T Stopka, Z Herceg, M Hollstein, J Zavadil, M Korenjak

Oncogene. 2017 Oct 26; 36(43): 6041–6048. Published online 2017 Jul 10. doi: 10.1038/onc.2017.215

PMCID:: PMC5666318

Article PDF–1.3M

Select item 49763626.

Molecular phylogenetic analysis of nuclear genes suggests a Cenozoic over-water dispersal origin for the Cuban solenodon

Jun J. Sato, Satoshi D. Ohdachi, Lazaro M. Echenique-Diaz, Rafael Borroto-Páez, Gerardo Begué-Quiala, Jorge L. Delgado-Labañino, Jorgelino Gámez-Díez, José Alvarez-Lemus, Son Truong Nguyen, Nobuyuki Yamaguchi, Masaki Kita

Sci Rep. 2016; 6: 31173. Published online 2016 Aug 8. doi: 10.1038/srep31173

PMCID:: PMC4976362

Article PDF–750K

Select item 49711557.

Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest

Gloria A. Santa-Gonzalez, Andrea Gomez-Molina, Mauricio Arcos-Burgos, Joel N. Meyer, Mauricio Camargo

Redox Biol. 2016 Oct; 9: 124–133. Published online 2016 Jul 21. doi: 10.1016/j.redox.2016.07.004

PMCID:: PMC4971155

Article PDF–1.7M

Select item 48933128.

Functional Assay for BRCA1: Mutagenesis of C-Terminal Region Reveals Critical Residues for Transcription Activation

Finbarr Hayes, Charmagne Cayanan, Daniela Barillá, Alvaro N.A. Monteiro

Cancer Res. Author manuscript; available in PMC 2016 Jun 4.

Published in final edited form as: Cancer Res. 2000 May 1; 60(9): 2411–2418.

PMCID:: PMC4893312

Article PDF–1.2M

Select item 48330999.

Tissue-Specific Effects of Valproic Acid on DNA Repair Genes and Apoptosis in Postimplantation Mouse Embryos

Christina Lamparter, Louise M. Winn

Toxicol Sci. 2014 Sep 1; 141(1): 59–67. Published online 2014 Sep 12. doi: 10.1093/toxsci/kfu105

PMCID:: PMC4833099

Article PDF–1.6M

Select item 475664910.

FUNCTIONAL ANALYSIS OF BRCA1 C-TERMINAL MISSENSE MUTATIONS IDENTIFIED IN BREAST AND OVARIAN CANCER FAMILIES

Johan Vallon-Christersson, Charmagne Cayanan, Karin Haraldsson, Niklas Loman, Jon Thor Bergthorsson, Karen Brøndum-Nielsen, Anne-Marie Gerdes, Pål Møller, Ulf Kristoffersson, Håkan Olsson, Åke Borg, Alvaro N.A. Monteiro

Hum Mol Genet. Author manuscript; available in PMC 2016 Feb 17.

Published in final edited form as: Hum Mol Genet. 2001 Feb 15; 10(4): 353–360. doi: 10.1093/hmg/10.4.353

PMCID:: PMC4756649

Article PDF–1.4M

Select item 475041811.

Cytosolic phospholipase A₂α regulates G₁ progression through modulating FOXO1 activity

Said Movahedi Naini, Gabriel J. Choukroun, James R. Ryan, Dirk M. Hentschel, Jagesh V. Shah, Joseph V. Bonventre

FASEB J. 2016 Mar; 30(3): 1155–1170. Published online 2015 Dec 7. doi: 10.1096/fj.15-278416

PMCID:: PMC4750418

Article

Select item 465732712.

Update of the human and mouse Fanconi anemia genes

Hongbin Dong, Daniel W. Nebert, Elspeth A. Bruford, David C. Thompson, Hans Joenje, Vasilis Vasiliou

Hum Genomics. 2015; 9: 32. Published online 2015 Nov 24. doi: 10.1186/s40246-015-0054-y

PMCID:: PMC4657327

Article PDF–1.0M

Select item 410892713.

The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA Repair

Bert Yu-Hung Chen, Cheng-Hsiang Huang, Ying-Hsi Lin, Ching-Chun Huang, Chu-Xia Deng, Lih-Ching Hsu

Sci Rep. 2014; 4: 5812. Published online 2014 Jul 24. doi: 10.1038/srep05812

PMCID:: PMC4108927

Article PDF–1.4M

Select item 364423914.

Phylogeny and chronology of the major lineages of New World hystricognath rodents: insights on the biogeography of the Eocene/Oligocene arrival of mammals in South America

Carolina M Voloch, Julio F Vilela, Leticia Loss-Oliveira, Carlos G Schrago

BMC Res Notes. 2013; 6: 160. Published online 2013 Apr 22. doi: 10.1186/1756-0500-6-160

PMCID:: PMC3644239

Article PDF–1.2M

Select item 362433015.

1918 Influenza Virus Hemagglutinin (HA) and the Viral RNA Polymerase Complex Enhance Viral Pathogenicity, but Only HA Induces Aberrant Host Responses in Mice

Tokiko Watanabe, Jennifer Tisoncik-Go, Nicolas Tchitchek, Shinji Watanabe, Arndt G. Benecke, Michael G. Katze, Yoshihiro Kawaoka

J Virol. 2013 May; 87(9): 5239–5254. doi: 10.1128/JVI.02753-12

PMCID:: PMC3624330

Article PDF–6.5M

Select item 353947016.

Radiation dose effect of DNA repair-related gene expression in mouse white blood cells

Ming-juan Li, Wei-wei Wang, Shi-wei Chen, Qian Shen, Rui Min

Med Sci Monit. 2011; 17(10): BR290–BR297. Published online 2011 Oct 1. doi: 10.12659/MSM.881976

PMCID:: PMC3539470

Article PDF–754K

Select item 346367517.

Cholesterol metabolite, 5-cholesten-3beta, 25-diol 3-sulfate, promotes hepatic proliferation in mice

Xin Zhang, Qianming Bai, Genta Kakiyama, Leyuan Xu, Jin Kyung Kim, William M. Pandak, Jr, Shunlin Ren

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2012 Nov; 132(3-5): 262–270. Published online 2012 Jun 23. doi: 10.1016/j.jsbmb.2012.06.001

PMCID:: PMC3463675

Article PDF–1.4M

Select item 322639918.

Proteomic Profiling of Adipose Tissue from Zmpste24^−/− Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

Juan R. Peinado, Pedro M. Quirós, Marina R. Pulido, Guillermo Mariño, Maria L. Martínez-Chantar, Rafael Vázquez-Martínez, José M. P. Freije, Carlos López-Otín, María M. Malagón

Mol Cell Proteomics. 2011 Nov; 10(11): M111.008094. Published online 2011 Aug 9. doi: 10.1074/mcp.M111.008094

PMCID:: PMC3226399

Article PDF–3.2M

Select item 317522819.

Differential transcriptomic profiles effected by oil palm phenolics indicate novel health outcomes

Soon-Sen Leow, Shamala Devi Sekaran, Kalyana Sundram, YewAi Tan, Ravigadevi Sambanthamurthi

BMC Genomics. 2011; 12: 432. Published online 2011 Aug 25. doi: 10.1186/1471-2164-12-432

PMCID:: PMC3175228

Article PDF–2.4M

Select item 291214720.

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

Dohoon Kim, Christopher L. Frank, Matthew M. Dobbin, Rachel K. Tsunemoto, Di Wu, Peter L. Peng, Ji-Song Guan, Byung-Hoon Lee, Lily Y. Moy, Paola Giusti, Nisha Broodie, Ralph Mazitschek, Ivanna Delalle, Stephen J. Haggarty, Rachael L. Neve, YouMing Lu, Li-Huei Tsai

Neuron. Author manuscript; available in PMC 2010 Jul 29.

Published in final edited form as: Neuron. 2008 Dec 10; 60(5): 803–817. doi: 10.1016/j.neuron.2008.10.015

PMCID:: PMC2912147

Article PDF–3.5M

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