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Select item 69264851.

Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function

Alexander Lercher, Anannya Bhattacharya, Alexandra M. Popa, Michael Caldera, Moritz F. Schlapansky, Hatoon Baazim, Benedikt Agerer, Bettina Gürtl, Lindsay Kosack, Peter Májek, Julia S. Brunner, Dijana Vitko, Theresa Pinter, Jakob-Wendelin Genger, Anna Orlova, Natalia Pikor, Daniela Reil, Maria Ozsvár-Kozma, Ulrich Kalinke, Burkhard Ludewig, Richard Moriggl, Keiryn L. Bennett, Jörg Menche, Paul N. Cheng, Gernot Schabbauer, Michael Trauner, Kristaps Klavins, Andreas Bergthaler

Immunity. 2019 Dec 17; 51(6): 1074–1087.e9. Published online 2019 Nov 26. doi: 10.1016/j.immuni.2019.10.014

PMCID:: PMC6926485

Abstract Article PDF–5.3M

Select item 68893762.

The lytic activity of VSV-GP treatment dominates the therapeutic effects in a syngeneic model of lung cancer

Liesa-Marie Schreiber, Carles Urbiola, Krishna Das, Bart Spiesschaert, Janine Kimpel, Fabian Heinemann, Birgit Stierstorfer, Philipp Müller, Monika Petersson, Patrik Erlmann, Dorothee von Laer, Guido Wollmann

Br J Cancer. 2019 Oct 15; 121(8): 647–658. Published online 2019 Sep 18. doi: 10.1038/s41416-019-0574-7

PMCID:: PMC6889376

Abstract Article PDF–2.4M

Select item 68744783.

Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection

Rachel A Liberatore, Emily J Mastrocola, Elena Cassella, Fabian Schmidt, Jessie R Willen, Dennis Voronin, Trinity M Zang, Theodora Hatziioannou, Paul D Bieniasz

eLife. 2019; 8: e49875. Published online 2019 Oct 23. doi: 10.7554/eLife.49875

PMCID:: PMC6874478

Abstract Article PDF–2.8M

Select item 67959974.

Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice

Mégane Nascimento, Aurélie Gombault, Norinne Lacerda-Queiroz, Corinne Panek, Florence Savigny, Malak Sbeity, Manon Bourinet, Marc Le Bert, Nicolas Riteau, Bernhard Ryffel, Valérie F. J. Quesniaux, Isabelle Couillin

Sci Rep. 2019; 9: 14848. Published online 2019 Oct 16. doi: 10.1038/s41598-019-51427-y

PMCID:: PMC6795997

Abstract Article PDF–2.5M

Select item 67257905.

Rapid Eye Movement Sleep Is Reduced in Prolactin-Deficient Mice

Ferenc Obál, Jr, Fabio Garcia-Garcia, Balint Kacsóh, Ping Taishi, Stewart Bohnet, Nelson D. Horseman, James M. Krueger

J Neurosci. 2005 Nov 2; 25(44): 10282–10289. doi: 10.1523/JNEUROSCI.2572-05.2005

PMCID:: PMC6725790

Abstract Article PDF–634K

Select item 64393276.

Type I interferon protects neurons from prions in in vivo models

Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Takayuki Fuse, Kazunori Sano, Katsuya Satoh, Tsuyoshi Mori, Ryuichiro Atarashi, Noriyuki Nishida

Brain. 2019 Apr; 142(4): 1035–1050. Published online 2019 Feb 7. doi: 10.1093/brain/awz016

PMCID:: PMC6439327

Abstract Article PDF–1.5M

Select item 54844887.

Interferon signaling in Peromyscus leucopus confers a potent and specific restriction to vector-borne flaviviruses

Adaeze O. Izuogu, Kristin L. McNally, Stephen E. Harris, Brian H. Youseff, John B. Presloid, Christopher Burlak, Jason Munshi-South, Sonja M. Best, R. Travis Taylor

PLoS One. 2017; 12(6): e0179781. Published online 2017 Jun 26. doi: 10.1371/journal.pone.0179781

PMCID:: PMC5484488

Abstract Article PDF–8.2M

Select item 49442898.

p53 Is a Host Cell Regulator during Herpes Simplex Encephalitis

Yuhei Maruzuru, Naoto Koyanagi, Naoki Takemura, Satoshi Uematsu, Daisuke Matsubara, Yutaka Suzuki, Jun Arii, Akihisa Kato, Yasushi Kawaguchi

J Virol. 2016 Aug 1; 90(15): 6738–6745. Prepublished online 2016 May 11. Published online 2016 Jul 11. doi: 10.1128/JVI.00846-16

PMCID:: PMC4944289

Abstract Article PDF–907K

Select item 42941109.

A novel 1,2-benzenediamine derivative FC-99 suppresses TLR3 expression and ameliorates disease symptoms in a mouse model of sepsis

Wei Gong, Erling Hu, Huan Dou, Yuxian Song, Liu Yang, Jianjian Ji, Erguang Li, Renxiang Tan, Yayi Hou

Br J Pharmacol. 2014 Nov; 171(21): 4866–4878. Published online 2014 Sep 23. doi: 10.1111/bph.12797

PMCID:: PMC4294110

Abstract Article PDF–1.9M

Select item 399596010.

Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells

Myles Robert Minter, Moses Zhang, Robert Charles Ates, Juliet Marie Taylor, Peter John Crack

J Neuroinflammation. 2014; 11: 43. Published online 2014 Mar 6. doi: 10.1186/1742-2094-11-43

PMCID:: PMC3995960

Abstract Article PDF–1.2M

Select item 371541811.

Negative Regulation of Type I IFN Expression by OASL1 Permits Chronic Viral Infection and CD8⁺ T-Cell Exhaustion

Myeong Sup Lee, Chan Hee Park, Yun Hee Jeong, Young-Joon Kim, Sang-Jun Ha

PLoS Pathog. 2013 Jul; 9(7): e1003478. Published online 2013 Jul 18. doi: 10.1371/journal.ppat.1003478

PMCID:: PMC3715418

Abstract Article PDF–2.3M

Select item 364819812.

Venezuelan Equine Encephalitis Replicon Particles Can Induce Rapid Protection against Foot-and-Mouth Disease Virus

Fayna Diaz-San Segundo, Camila C. A. Dias, Mauro P. Moraes, Marcelo Weiss, Eva Perez-Martin, Gary Owens, Max Custer, Kurt Kamrud, Teresa de los Santos, Marvin J. Grubman

J Virol. 2013 May; 87(10): 5447–5460. doi: 10.1128/JVI.03462-12

PMCID:: PMC3648198

Abstract Article PDF–2.6M

Select item 361609813.

Generation of Mast Cells from Mouse Fetus: Analysis of Differentiation and Functionality, and Transcriptome Profiling Using Next Generation Sequencer

Nobuyuki Fukuishi, Yuusuke Igawa, Tomoyo Kunimi, Hirofumi Hamano, Masao Toyota, Hironobu Takahashi, Hiromichi Kenmoku, Yasuyuki Yagi, Nobuaki Matsui, Masaaki Akagi

PLoS One. 2013; 8(4): e60837. Published online 2013 Apr 3. doi: 10.1371/journal.pone.0060837

PMCID:: PMC3616098

Abstract Article PDF–2.8M

Select item 335509014.

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, Ganes C. Sen

PLoS Pathog. 2012 May; 8(5): e1002712. Published online 2012 May 17. doi: 10.1371/journal.ppat.1002712

PMCID:: PMC3355090

Abstract Article PDF–3.4M

Select item 319762015.

ISG15 Is Critical in the Control of Chikungunya Virus Infection Independent of UbE1L Mediated Conjugation

Scott W. Werneke, Clementine Schilte, Anjali Rohatgi, Kristen J. Monte, Alain Michault, Fernando Arenzana-Seisdedos, Dana L. Vanlandingham, Stephen Higgs, Arnaud Fontanet, Matthew L. Albert, Deborah J. Lenschow

PLoS Pathog. 2011 Oct; 7(10): e1002322. Published online 2011 Oct 20. doi: 10.1371/journal.ppat.1002322

PMCID:: PMC3197620

Abstract Article PDF–963K

Select item 309821816.

Type I Interferon Production Induced by Streptococcus pyogenes-Derived Nucleic Acids Is Required for Host Protection

Nina Gratz, Harald Hartweger, Ulrich Matt, Franz Kratochvill, Marton Janos, Stefanie Sigel, Barbara Drobits, Xiao-Dong Li, Sylvia Knapp, Pavel Kovarik

PLoS Pathog. 2011 May; 7(5): e1001345. Published online 2011 May 19. doi: 10.1371/journal.ppat.1001345