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Select item 70056221.

Myopathy reversion in mice after restauration of mitochondrial complex I

Claudia V Pereira, Susana Peralta, Tania Arguello, Sandra R Bacman, Francisca Diaz, Carlos T Moraes

EMBO Mol Med. 2020 Feb 7; 12(2): e10674. Published online 2020 Jan 9. doi: 10.15252/emmm.201910674

PMCID:: PMC7005622

Abstract Article PDF–1.8M

Select item 69426932.

MitoTALEN reduces mutant mtDNA load and restores tRNA^Ala levels in a mouse model of heteroplasmic mtDNA mutation

Sandra R. Bacman, Johanna H. K. Kauppila, Claudia V. Pereira, Nadee Nissanka, Maria Miranda, Milena Pinto, Sion L. Williams, Nils-Göran Larsson, James B. Stewart, Carlos T. Moraes

Nat Med. Author manuscript; available in PMC 2020 Jan 5.

Published in final edited form as: Nat Med. 2018 Nov; 24(11): 1696–1700. Published online 2018 Sep 24. doi: 10.1038/s41591-018-0166-8

Correction in:: Nat Med. 2018 Oct 5

PMCID:: PMC6942693

Abstract Article PDF–1.1M

Select item 69214733.

The second genome: Effects of the mitochondrial genome on cancer progression

Adam D. Scheid, Thomas C. Beadnell, Danny R. Welch

Adv Cancer Res. Author manuscript; available in PMC 2020 Feb 27.

Published in final edited form as: Adv Cancer Res. 2019; 142: 63–105. Published online 2019 Feb 27. doi: 10.1016/bs.acr.2019.01.001

PMCID:: PMC6921473

Abstract Article PDF–644K

Select item 69084634.

Genomic Features of Rickettsia heilongjiangensis Revealed by Intraspecies Comparison and Detailed Comparison With Rickettsia japonica

Kentaro Kasama, Hiromi Fujita, Seigo Yamamoto, Tadasuke Ooka, Yasuhiro Gotoh, Yoshitoshi Ogura, Shuji Ando, Tetsuya Hayashi

Front Microbiol. 2019; 10: 2787. Published online 2019 Dec 6. doi: 10.3389/fmicb.2019.02787

PMCID:: PMC6908463

Abstract Article PDF–4.1M

Select item 69072415.

Effective machine-learning assembly for next-generation amplicon sequencing with very low coverage

Louis Ranjard, Thomas K. F. Wong, Allen G. Rodrigo

BMC Bioinformatics. 2019; 20: 654. Published online 2019 Dec 11. doi: 10.1186/s12859-019-3287-2

Correction in:: BMC Bioinformatics. 2020; 21: 24.

PMCID:: PMC6907241

Abstract Article PDF–1.4M

Select item 68963176.

Increased mitochondrial DNA copy number protects hair cells and HEI-OC1 cells against drug-induced apoptosis

Honglin Mei, Dongmei Mei, Huiqian Yu, Shan Sun, Yan Chen, Yanping Zhang, Renjie Chai, Huawei Li

Mol Med Rep. 2020 Jan; 21(1): 338–346. Published online 2019 Nov 20. doi: 10.3892/mmr.2019.10838

PMCID:: PMC6896317

Abstract Article PDF–1.1M

Select item 68532967.

Genome-wide identification of short 2′,3′-cyclic phosphate-containing RNAs and their regulation in aging

Megumi Shigematsu, Keisuke Morichika, Takuya Kawamura, Shozo Honda, Yohei Kirino

PLoS Genet. 2019 Nov; 15(11): e1008469. Published online 2019 Nov 13. doi: 10.1371/journal.pgen.1008469

PMCID:: PMC6853296

Abstract Article PDF–2.3M

Select item 68240708.

What can a comparative genomics approach tell us about the pathogenicity of mtDNA mutations in human populations?

Hannah O'Keefe, Rachel Queen, Phillip Lord, Joanna L. Elson

Evol Appl. 2019 Dec; 12(10): 1912–1930. Published online 2019 Aug 27. doi: 10.1111/eva.12851

PMCID:: PMC6824070

Abstract Article PDF–1.9M

Select item 66787659.

Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells

Joaquín Marco-Brualla, Sameer Al-Wasaby, Ruth Soler, Eduardo Romanos, Blanca Conde, Raquel Justo-Méndez, José A. Enríquez, Patricio Fernández-Silva, Luis Martínez-Lostao, Martín Villalba, Raquel Moreno-Loshuertos, Alberto Anel

Cancers (Basel) 2019 Jul; 11(7): 1027. Published online 2019 Jul 21. doi: 10.3390/cancers11071027

PMCID:: PMC6678765

Abstract Article PDF–6.8M

Select item 665157410.

Deletion of OGG1 Results in a Differential Signature of Oxidized Purine Base Damage in mtDNA Regions

Guglielmina Chimienti, Vito Pesce, Flavio Fracasso, Francesco Russo, Nadja Cristhina de Souza-Pinto, Vilhelm A. Bohr, Angela Maria Serena Lezza

Int J Mol Sci. 2019 Jul; 20(13): 3302. Published online 2019 Jul 5. doi: 10.3390/ijms20133302

PMCID:: PMC6651574

Abstract Article PDF–1.0M

Select item 663715211.

Gas6 is a reciprocal regulator of mitophagy during mammalian oocyte maturation

Kyeoung-Hwa Kim, Eun-Young Kim, Jung-Jae Ko, Kyung-Ah Lee

Sci Rep. 2019; 9: 10343. Published online 2019 Jul 17. doi: 10.1038/s41598-019-46459-3

PMCID:: PMC6637152

Abstract Article PDF–4.0M

Select item 662993812.

Maturation of White Adipose Tissue Function in C57BL/6j Mice From Weaning to Young Adulthood

Andrea Kodde, Eefje Engels, Annemarie Oosting, Kees van Limpt, Eline M. van der Beek, Jaap Keijer

Front Physiol. 2019; 10: 836. Published online 2019 Jul 9. doi: 10.3389/fphys.2019.00836

PMCID:: PMC6629938

Abstract Article PDF–3.4M

Select item 661406213.

ImtRDB: a database and software for mitochondrial imperfect interspersed repeats annotation

Viktor N. Shamanskiy, Valeria N. Timonina, Konstantin Yu. Popadin, Konstantin V. Gunbin

BMC Genomics. 2019; 20(Suppl 3): 295. Published online 2019 May 8. doi: 10.1186/s12864-019-5536-1

Correction in:: BMC Genomics. 2019; 20: 556.

PMCID:: PMC6614062

Abstract Article PDF–4.2M

Select item 660910514.

Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

Janeesh Plakkal Ayyappan, Kezia lizardo, Sean Wang, Edward Yurkow, Jyothi F Nagajyothi

Biomol Ther (Seoul) 2019 Jul; 27(4): 386–394. Published online 2019 Mar 13. doi: 10.4062/biomolther.2018.193

PMCID:: PMC6609105

Abstract Article PDF–6.8M

Select item 660682315.

Ginsenoside Rg1 augments oxidative metabolism and anabolic response of skeletal muscle in mice

Hyeon-Ju Jeong, Hyun-Kyung So, Ayoung Jo, Hye-Been Kim, Sang-Jin Lee, Gyu-Un Bae, Jong-Sun Kang

J Ginseng Res. 2019 Jul; 43(3): 475–481. Published online 2018 May 4. doi: 10.1016/j.jgr.2018.04.005

PMCID:: PMC6606823

Abstract Article PDF–2.2M

Select item 658235416.

The mitochondrial R-loop

Ian J Holt

Nucleic Acids Res. 2019 Jun 20; 47(11): 5480–5489. Published online 2019 May 2. doi: 10.1093/nar/gkz277

PMCID:: PMC6582354

Abstract Article PDF–1.6M

Select item 658234117.

Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing

Ritika Grover, Shaunak A Burse, Shambhavi Shankrit, Ayush Aggarwal, Kritika Kirty, Kiran Narta, Rajpal Srivastav, Ashwini Kumar Ray, Garima Malik, Archana Vats, Rajender K Motiani, Lipi Thukral, Soumya Sinha Roy, Sudha Bhattacharya, Rakesh Sharma, Krishnamurthy Natarajan, Mitali Mukerji, Rajesh Pandey, Rajesh S Gokhale, Vivek T Natarajan

Nucleic Acids Res. 2019 Jun 20; 47(11): 5852–5866. Published online 2019 May 13. doi: 10.1093/nar/gkz371

PMCID:: PMC6582341

Abstract Article PDF–6.1M

Select item 657207518.

Dexamethasone-Induced Mitochondrial Dysfunction and Insulin Resistance-Study in 3T3-L1 Adipocytes and Mitochondria Isolated from Mouse Liver

Guangxiang Luan, Gang Li, Xiao Ma, Youcai Jin, Na Hu, Ji Li, Zhenhua Wang, Honglun Wang

Molecules. 2019 May; 24(10): 1982. Published online 2019 May 23. doi: 10.3390/molecules24101982

PMCID:: PMC6572075

Abstract Article PDF–2.9M

Select item 655369519.

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

Eduardo Silva Ramos, Elisa Motori, Christian Brüser, Inge Kühl, Assa Yeroslaviz, Benedetta Ruzzenente, Johanna H. K. Kauppila, Jakob D. Busch, Kjell Hultenby, Bianca H. Habermann, Stefan Jakobs, Nils-Göran Larsson, Arnaud Mourier

PLoS Genet. 2019 Jun; 15(6): e1008085. Published online 2019 Jun 6. doi: 10.1371/journal.pgen.1008085

PMCID:: PMC6553695

Abstract Article PDF–3.2M

Select item 642834420.

ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy

Mark T. Handley, Kaalak Reddy, Jimi Wills, Elisabeth Rosser, Archith Kamath, Mihail Halachev, Gavin Falkous, Denise Williams, Phillip Cox, Alison Meynert, Eleanor S. Raymond, Harris Morrison, Stephen Brown, Emma Allan, Irene Aligianis, Andrew P. Jackson, Bernard H. Ramsahoye, Alex von Kriegsheim, Robert W. Taylor, Andrew J. Finch, David R. FitzPatrick

PLoS Genet. 2019 Mar; 15(3): e1007605. Published online 2019 Mar 11. doi: 10.1371/journal.pgen.1007605