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Select item 69328161.

A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

Thomas Günther, Jacqueline Fröhlich, Christina Herrde, Shinji Ohno, Lia Burkhardt, Heiko Adler, Adam Grundhoff

PLoS Pathog. 2019 Oct; 15(10): e1007838. Published online 2019 Oct 31. doi: 10.1371/journal.ppat.1007838

PMCID:: PMC6932816

Abstract Article PDF–5.3M

Select item 66493142.

Kaposi Sarcoma in Mantled Guereza

Anna Grewer, Martina Bleyer, Kerstin Mätz-Rensing, Alexander S. Hahn, Tim Rüggeberg, Gregor Babaryka, Andre Zimmermann, Stefan Pöhlmann, Artur Kaul

Emerg Infect Dis. 2019 Aug; 25(8): 1552–1555. doi: 10.3201/eid2508.181804

PMCID:: PMC6649314

Abstract Article PDF–2.0M

Select item 65413083.

An integrative approach identifies direct targets of the late viral transcription complex and an expanded promoter recognition motif in Kaposi’s sarcoma-associated herpesvirus

Divya Nandakumar, Britt Glaunsinger

PLoS Pathog. 2019 May; 15(5): e1007774. Published online 2019 May 16. doi: 10.1371/journal.ppat.1007774

PMCID:: PMC6541308

Abstract Article PDF–2.8M

Select item 65022524.

Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO)

Christian M. Zmasek, David M. Knipe, Philip E. Pellett, Richard H. Scheuermann

Virology. 2019 Mar; 529: 29–42. Published online 2019 Jan 6. doi: 10.1016/j.virol.2019.01.005

PMCID:: PMC6502252

Abstract Article PDF–2.1M

Select item 64727595.

KSHV lytic proteins K-RTA and K8 bind to cellular and viral chromatin to modulate gene expression

Rajeev Kaul, Pravinkumar Purushothaman, Timsy Uppal, Subhash C. Verma

PLoS One. 2019; 14(4): e0215394. Published online 2019 Apr 18. doi: 10.1371/journal.pone.0215394

PMCID:: PMC6472759

Abstract Article PDF–1.7M

Select item 64014406.

Comparative Analysis of Gammaherpesvirus Circular RNA Repertoires: Conserved and Unique Viral Circular RNAs

Nathan A. Ungerleider, Vaibhav Jain, Yiping Wang, Nicholas J. Maness, Robert V. Blair, Xavier Alvarez, Cecily Midkiff, Dennis Kolson, Shanshan Bai, Claire Roberts, Walter N. Moss, Xia Wang, Jacqueline Serfecz, Michael Seddon, Terri Lehman, Tianfang Ma, Yan Dong, Rolf Renne, Scott A. Tibbetts, Erik K. Flemington

J Virol. 2019 Mar 15; 93(6): e01952-18. Prepublished online 2018 Dec 19. Published online 2019 Mar 5. doi: 10.1128/JVI.01952-18

PMCID:: PMC6401440

Abstract Article PDF–2.0M

Select item 63840737.

Genome-Wide Identification of Direct RTA Targets Reveals Key Host Factors for Kaposi’s Sarcoma-Associated Herpesvirus Lytic Reactivation

Bernadett Papp, Naeem Motlagh, Richard J. Smindak, Seung Jin Jang, Aria Sharma, Juan D. Alonso, Zsolt Toth

J Virol. 2019 Mar 1; 93(5): e01978-18. Prepublished online 2018 Dec 12. Published online 2019 Feb 19. doi: 10.1128/JVI.01978-18

PMCID:: PMC6384073

Abstract Article PDF–3.7M

Select item 63717498.

Evolutionary effects of the AID/APOBEC family of mutagenic enzymes on human gamma-herpesviruses

Teresa Martinez, Maxwell Shapiro, Sumita Bhaduri-McIntosh, Thomas MacCarthy

Virus Evol. 2019 Jan; 5(1): vey040. Published online 2019 Feb 11. doi: 10.1093/ve/vey040

PMCID:: PMC6371749

Abstract Article PDF–450K

Select item 63281449.

Screening human cell lines for viral infections applying RNA-Seq data analysis

Cord C. Uphoff, Claudia Pommerenke, Sabine A. Denkmann, Hans G. Drexler

PLoS One. 2019; 14(1): e0210404. Published online 2019 Jan 10. doi: 10.1371/journal.pone.0210404

PMCID:: PMC6328144

Abstract Article PDF–1.5M

Select item 631234810.

Quantitative RNAseq analysis of Ugandan KS tumors reveals KSHV gene expression dominated by transcription from the LTd downstream latency promoter

Timothy M. Rose, A. Gregory Bruce, Serge Barcy, Matt Fitzgibbon, Lisa R. Matsumoto, Minako Ikoma, Corey Casper, Jackson Orem, Warren Phipps

PLoS Pathog. 2018 Dec; 14(12): e1007441. Published online 2018 Dec 17. doi: 10.1371/journal.ppat.1007441

PMCID:: PMC6312348

Abstract Article PDF–5.1M

Select item 629491311.

Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA

Takanobu Tagawa, Shaojian Gao, Vishal N. Koparde, Mileidy Gonzalez, John L. Spouge, Anna P. Serquiña, Kathryn Lurain, Ramya Ramaswami, Thomas S. Uldrick, Robert Yarchoan, Joseph M. Ziegelbauer

Proc Natl Acad Sci U S A. 2018 Dec 11; 115(50): 12805–12810. Published online 2018 Nov 19. doi: 10.1073/pnas.1816183115

PMCID:: PMC6294913

Abstract Article PDF–1.1M

Select item 625468512.

Polymorphisms in KSHV-encoded microRNA sequences affect levels of mature viral microRNA in Kaposi Sarcoma lesions

Vickie A. Marshall, Nazzarena Labo, Joanna Sztuba-Solinska, Elena M. Cornejo Castro, Karen Aleman, Kathleen M. Wyvill, Lynne McNamara, Stuart F.J. Le Grice, Robert Yarchoan, Thomas S. Uldrick, Patrick MacPhail, Mark N. Polizzotto, Denise Whitby

Oncotarget. 2018 Nov 9; 9(88): 35856–35869. Published online 2018 Nov 9. doi: 10.18632/oncotarget.26321

PMCID:: PMC6254685

Abstract Article PDF–4.2M

Select item 619566213.

Genome-Wide Sequence Analysis of Kaposi Sarcoma-Associated Herpesvirus Shows Diversification Driven by Recombination

Neneh Sallah, Anne L Palser, Simon J Watson, Nazzarena Labo, Gershim Asiki, Vickie Marshall, Robert Newton, Denise Whitby, Paul Kellam, Inês Barroso

J Infect Dis. 2018 Dec 1; 218(11): 1700–1710. Published online 2018 Jul 14. doi: 10.1093/infdis/jiy427

PMCID:: PMC6195662

Abstract Article PDF–2.8M

Select item 619255414.

In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals

Douglas G. Widman, Savanna Gornisiewicz, Sharon Shacham, Sharon Tamir

PLoS One. 2018; 13(10): e0200043. Published online 2018 Oct 17. doi: 10.1371/journal.pone.0200043

PMCID:: PMC6192554

Abstract Article PDF–2.2M

Select item 613681615.

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency

Sharon E. Hopcraft, Samantha G. Pattenden, Lindsey I. James, Stephen Frye, Dirk P. Dittmer, Blossom Damania

PLoS Pathog. 2018 Sep; 14(9): e1007267. Published online 2018 Sep 13. doi: 10.1371/journal.ppat.1007267

PMCID:: PMC6136816

Abstract Article PDF–5.8M

Select item 600270916.

Kaposi's Sarcoma-Associated Herpesvirus mRNA Accumulation in Nuclear Foci Is Influenced by Viral DNA Replication and Viral Noncoding Polyadenylated Nuclear RNA

Tenaya K. Vallery, Johanna B. Withers, Joana A. Andoh, Joan A. Steitz

J Virol. 2018 Jul 1; 92(13): e00220-18. Prepublished online 2018 Apr 11. Published online 2018 Jun 13. doi: 10.1128/JVI.00220-18

PMCID:: PMC6002709

Abstract Article PDF–4.2M

Select item 579202717.

RNA-Seq of Kaposi’s sarcoma reveals alterations in glucose and lipid metabolism

For Yue Tso, Andrew V. Kossenkov, Salum J. Lidenge, Owen Ngalamika, John R. Ngowi, Julius Mwaiselage, Jayamanna Wickramasinghe, Eun Hee Kwon, John T. West, Paul M. Lieberman, Charles Wood

PLoS Pathog. 2018 Jan; 14(1): e1006844. Published online 2018 Jan 19. doi: 10.1371/journal.ppat.1006844

PMCID:: PMC5792027

Abstract Article PDF–9.2M

Select item 577488918.

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation

Stephanie A. Moquin, Sean Thomas, Sean Whalen, Alix Warburton, Samantha G. Fernandez, Alison A. McBride, Katherine S. Pollard, JJ L. Miranda

J Virol. 2018 Feb 1; 92(3): e01413-17. Prepublished online 2017 Nov 15. Published online 2018 Jan 17. doi: 10.1128/JVI.01413-17

PMCID:: PMC5774889

Abstract Article PDF–1.1M

Select item 575435919.

KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation

Mel Campbell, Tadashi Watanabe, Kazushi Nakano, Ryan R. Davis, Yuanzhi Lyu, Clifford G. Tepper, Blythe Durbin-Johnson, Masahiro Fujimuro, Yoshihiro Izumiya

Nat Commun. 2018; 9: 49. Published online 2018 Jan 4. doi: 10.1038/s41467-017-02089-9