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Select item 70273641.

Comprehensive Molecular Profiling for Relapsed/Refractory Pediatric Burkitt Lymphomas—Retrospective Analysis of Three Real-Life Clinical Cases—Addressing Issues on Randomization and Customization at the Bedside

Kristyna Polaskova, Tomas Merta, Alexandra Martincekova, Danica Zapletalova, Michal Kyr, Pavel Mazanek, Zdenka Krenova, Peter Mudry, Marta Jezova, Jiri Tuma, Jarmila Skotakova, Ivana Cervinkova, Dalibor Valik, Lenka Zdrazilova-Dubska, Hana Noskova, Karol Pal, Ondrej Slaby, Pavel Fabian, Sarka Kozakova, Jakub Neradil, Renata Veselska, Veronika Kanderova, Ondrej Hrusak, Tomas Freiberger, Giannoula Lakka Klement, Jaroslav Sterba

Front Oncol. 2019; 9: 1531. Published online 2020 Feb 7. doi: 10.3389/fonc.2019.01531

PMCID:: PMC7027364

Abstract Article PDF–796K

Select item 70271952.

Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions

Ganesh Warthi, Pierre-Edouard Fournier, Hervé Seligmann

Front Genet. 2020; 11: 42. Published online 2020 Feb 11. doi: 10.3389/fgene.2020.00042

PMCID:: PMC7027195

Abstract Article PDF–1.2M

Select item 69987463.

Development and Validation of a 34-Gene Inherited Cancer Predisposition Panel Using Next-Generation Sequencing

Sun Hee Rosenthal, Weimin Sun, Ke Zhang, Yan Liu, Quoclinh Nguyen, Anna Gerasimova, Camille Nery, Linda Cheng, Carolyn Castonguay, Elaine Hiller, James Li, Christopher Elzinga, David Wolfson, Alla Smolgovsky, Rebecca Chen, Arlene Buller-Burckle, Joseph Catanese, Andrew Grupe, Felicitas Lacbawan, Renius Owen

Biomed Res Int. 2020; 2020: 3289023. Published online 2020 Jan 22. doi: 10.1155/2020/3289023

PMCID:: PMC6998746

Abstract Article PDF–443K

Select item 69905244.

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

Vahinipriya Manoharan, Eric Hamilton Karunanayake, Kamani Hemamala Tennekoon, Sumadee De Silva, Ahamed Ilyas Ahamed Imthikab, Kanishka De Silva, Preethika Angunawela, Sameera Vishwakula, John Lunec

BMC Cancer. 2020; 20: 72. Published online 2020 Jan 30. doi: 10.1186/s12885-020-6573-5

PMCID:: PMC6990524

Abstract Article PDF–1.8M

Select item 69805715.

Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design

Almudena Aguilera-Diaz, Iria Vazquez, Beñat Ariceta, Amagoia Mañú, Zuriñe Blasco-Iturri, Sara Palomino-Echeverría, María José Larrayoz, Ramón García-Sanz, María Isabel Prieto-Conde, María del Carmen Chillón, Ana Alfonso-Pierola, Felipe Prosper, Marta Fernandez-Mercado, María José Calasanz

PLoS One. 2020; 15(1): e0227986. Published online 2020 Jan 24. doi: 10.1371/journal.pone.0227986

PMCID:: PMC6980571

Abstract Article PDF–2.0M

Select item 69424206.

TP53 alterations in relapsed childhood acute lymphoblastic leukemia

Chih‐Hsiang Yu, Wan‐Ting Chang, Shiann‐Tarng Jou, Tze‐Kang Lin, Ya‐Hsuan Chang, Chien‐Yu Lin, Kai‐Hsin Lin, Meng‐Yao Lu, Shu‐Huey Chen, Kang‐Hsi Wu, Shih‐Chung Wang, Hsiu‐Hao Chang, Yi‐Ning Su, Chia‐Cheng Hung, Dong‐Tsamn Lin, Hsuan‐Yu Chen, Yung‐Li Yang

Cancer Sci. 2020 Jan; 111(1): 229–238. Published online 2019 Dec 5. doi: 10.1111/cas.14238

PMCID:: PMC6942420

Abstract Article PDF–719K

Select item 69394017.

IRF1 Negatively Regulates Oncogenic KPNA2 Expression Under Growth Stimulation and Hypoxia in Lung Cancer Cells

Jie-Xin Huang, Yi-Cheng Wu, Ya-Yun Cheng, Chih-Liang Wang, Chia-Jung Yu

Onco Targets Ther. 2019; 12: 11475–11486. Published online 2019 Dec 27. doi: 10.2147/OTT.S221832

PMCID:: PMC6939401

Abstract Article PDF–3.7M

Select item 69127428.

Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation

Ming Hong, Jinke Li, Siying Li, Mohammed M.Almutairi

Cells. 2019 Nov; 8(11): 1466. Published online 2019 Nov 19. doi: 10.3390/cells8111466

Retraction in:: Cells. 2020 Aug; 9(8): 1814.

PMCID:: PMC6912742

Abstract Article

Select item 68383909.

Accumulation of mitochondrial 7S DNA in idiopathic and LRRK2 associated Parkinson's disease

Petar Podlesniy, Margalida Puigròs, Núria Serra, Rubén Fernández-Santiago, Mario Ezquerra, Eduardo Tolosa, Ramon Trullas

EBioMedicine. 2019 Oct; 48: 554–567. Published online 2019 Oct 17. doi: 10.1016/j.ebiom.2019.09.015

PMCID:: PMC6838390

Abstract Article PDF–2.9M

Select item 683211010.

Validation and Classification of Atypical Splicing Variants Associated With Osteogenesis Imperfecta

Lulu Li, Yixuan Cao, Feiyue Zhao, Bin Mao, Xiuzhi Ren, Yanzhou Wang, Yun Guan, Yi You, Shan Li, Tao Yang, Xiuli Zhao

Front Genet. 2019; 10: 979. Published online 2019 Oct 18. doi: 10.3389/fgene.2019.00979

PMCID:: PMC6832110

Abstract Article PDF–5.1M

Select item 682626611.

Nucleotide variations of TP53 exon 4 found in intracranial meningioma and in silico prediction of their significance

Anja Bukovac, Anja Kafka, Reno Hrašćan, Tomislav Vladušić, Nives Pećina-Šlaus

Mol Clin Oncol. 2019 Dec; 11(6): 563–572. Published online 2019 Oct 15. doi: 10.3892/mco.2019.1936

PMCID:: PMC6826266

Abstract Article PDF–1.1M

Select item 675517212.

Synergistic effect of STAT3-targeted small interfering RNA and AZD0530 against glioblastoma in vitro and in vivo

Qingjun Liu, Leibo Wang, David Li, Jingxia Zhao, Shen Chen, Jialin Li

Mol Med Rep. 2019 Oct; 20(4): 3625–3632. Published online 2019 Aug 21. doi: 10.3892/mmr.2019.10596

PMCID:: PMC6755172

Abstract Article PDF–796K

Select item 673232013.

Five novel NF1 gene pathogenic variants in 10 different Chinese families with neurofibromatosis type 1

Linlin Chen, Feng Xue, Jia Xu, Jinwei He, Wenzhen Fu, Zhenlin Zhang, Qinglin Kang

Mol Genet Genomic Med. 2019 Sep; 7(9): e904. Published online 2019 Jul 25. doi: 10.1002/mgg3.904

PMCID:: PMC6732320

Abstract Article PDF–1.1M

Select item 672739114.

A cross-sectional study on factors associated with hypertension and genetic polymorphisms of renin-angiotensin-aldosterone system in Chinese hui pilgrims to hajj

Yinxia Zhang, Fangfang Shi, Zhanbiao Yu, Aimin Yang, Maolan Zeng, Jiaoyue Wang, Haiping Yin, Benzhong Zhang, Xiao Ma

BMC Public Health. 2019; 19: 1223. Published online 2019 Sep 4. doi: 10.1186/s12889-019-7357-1

PMCID:: PMC6727391

Abstract Article PDF–1.7M

Select item 671758815.

TP53, ETV6 and RUNX1 germline variants in a case series of patients developing secondary neoplasms after treatment for childhood acute lymphoblastic leukemia

Stefanie V. Junk, Norman Klein, Sabine Schreek, Martin Zimmermann, Anja Möricke, Kirsten Bleckmann, Julia Alten, Elif Dagdan, Gunnar Cario, Christian P. Kratz, Martin Schrappe, Martin Stanulla

Haematologica. 2019 Sep; 104(9): e402–e405. doi: 10.3324/haematol.2018.205849

PMCID:: PMC6717588

Article PDF–726K

Select item 670217516.

The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer

Marina Kazantseva, Sunali Mehta, Ramona A. Eiholzer, Gregory Gimenez, Sara Bowie, Hamish Campbell, Ashley L. Reily-Bell, Imogen Roth, Sankalita Ray, Catherine J. Drummond, Glen Reid, Sebastien M. Joruiz, Anna Wiles, Helen R. Morrin, Karen L. Reader, Noelyn A. Hung, Margaret A. Baird, Tania L. Slatter, Antony W. Braithwaite

Cell Death Dis. 2019 Sep; 10(9): 631. Published online 2019 Aug 20. doi: 10.1038/s41419-019-1861-1

PMCID:: PMC6702175

Abstract Article PDF–3.1M

Select item 669513817.

A research-based gene panel to investigate breast, ovarian and prostate cancer genetic risk

Madison R. Bishop, Anna L. W. Huskey, John Hetzel, Nancy D. Merner

PLoS One. 2019; 14(8): e0220929. Published online 2019 Aug 15. doi: 10.1371/journal.pone.0220929

PMCID:: PMC6695138

Abstract Article PDF–1.6M

Select item 669427218.

Differential expression of genes associated with hypoxia pathway on bone marrow stem cells in osteoporosis patients with different bone mass index

Qi Zhu, Chang Shan, Ling Li, Lige Song, Keqin Zhang, Yun Zhou

Ann Transl Med. 2019 Jul; 7(14): 309. doi: 10.21037/atm.2019.06.27

PMCID:: PMC6694272

Abstract Article PDF–3.5M

Select item 665943919.

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects

Tej H. Patel, Lucas Norman, Steven Chang, Sina Abedi, Catherine Liu, Marilyn Chwa, Shari R. Atilano, Kunal Thaker, Stephanie Lu, S. Michal Jazwinski, Michael V. Miceli, Nitin Udar, Daniela Bota, M. Cristina Kenney

Front Oncol. 2019; 9: 640. Published online 2019 Jul 19. doi: 10.3389/fonc.2019.00640

PMCID:: PMC6659439

Abstract Article PDF–1.8M

Select item 662503020.

TFAP2C increases cell proliferation by downregulating GADD45B and PMAIP1 in non-small cell lung cancer cells

Hyunhee Do, Dain Kim, JiHoon Kang, Beomseok Son, Danbi Seo, HyeSook Youn, BuHyun Youn, Wanyeon Kim

Biol Res. 2019; 52: 35. Published online 2019 Jul 11. doi: 10.1186/s40659-019-0244-5

PMCID:: PMC6625030

Abstract Article PDF–2.1M

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