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Select item 69491131.

Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus

Steven S. Good, Adel Moussa, Xiao-Jian Zhou, Keith Pietropaolo, Jean-Pierre Sommadossi

PLoS One. 2020; 15(1): e0227104. Published online 2020 Jan 8. doi: 10.1371/journal.pone.0227104

PMCID:: PMC6949113

Abstract Article PDF–2.2M

Select item 67975372.

Genome Sequence of an Unknown Subtype of Hepatitis C Virus Genotype 6: Another Piece for the Taxonomic Puzzle

Martin Schou Pedersen, Sarah Mollerup, Lone Gilmor Nielsen, Håvard Jenssen, Jens Bukh, Kristian Schønning

Microbiol Resour Announc. 2019 Oct; 8(42): e01030-19. Published online 2019 Oct 17. doi: 10.1128/MRA.01030-19

PMCID:: PMC6797537

Abstract Article PDF–624K

Select item 67856773.

Hepatitis C virus genotype 1 and 2 recombinant genomes and the phylogeographic history of the 2k/1b lineage

Reilly Hostager, Manon Ragonnet-Cronin, Ben Murrell, Charlotte Hedskog, Anu Osinusi, Simone Susser, Christoph Sarrazin, Evguenia Svarovskaia, Joel O Wertheim

Virus Evol. 2019 Jul; 5(2): vez041. Published online 2019 Oct 9. doi: 10.1093/ve/vez041

PMCID:: PMC6785677

Abstract Article PDF–526K

Select item 67568304.

Computational analysis of naturally occurring resistance-associated substitutions in genes NS3, NS5A, and NS5B among 86 subtypes of hepatitis C virus worldwide

Ruihong Wu, Dongfeng Geng, Xiumei Chi, Xiaomei Wang, Xiuzhu Gao, Hongqin Xu, Ying Shi, Yazhe Guan, Yang Wang, Jinglan Jin, Yanhua Ding, Junqi Niu

Infect Drug Resist. 2019; 12: 2987–3015. Published online 2019 Sep 19. doi: 10.2147/IDR.S218584

PMCID:: PMC6756830

Abstract Article PDF–2.8M

Select item 67394845.

Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir

Peter A.C. Wing, Meleri Jones, Michelle Cheung, Sampath DaSilva, Connor Bamford, Wing-Yiu Jason Lee, Elihu Aranday-Cortes, Ana Da Silva Filipe, John McLauchlan, David Smith, William Irving, Morven Cunningham, Azim Ansari, Eleanor Barnes, Graham R. Foster

Gastroenterology. 2019 Sep; 157(3): 692–704.e9. doi: 10.1053/j.gastro.2019.05.007

PMCID:: PMC6739484

Abstract Article

Select item 65493706.

TAR-VIR: a pipeline for TARgeted VIRal strain reconstruction from metagenomic data

Jiao Chen, Jiating Huang, Yanni Sun

BMC Bioinformatics. 2019; 20: 305. Published online 2019 Jun 4. doi: 10.1186/s12859-019-2878-2

PMCID:: PMC6549370

Abstract Article PDF–1.0M

Select item 65488987.

Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era

Luisa Salazar-Vizcaya, Roger D Kouyos, Karin J Metzner, Kamila Caraballo Cortes, Jürg Böni, Cyril Shah, Jan Fehr, Dominique L Braun, Enos Bernasconi, Herbert A Mbunkah, Matthias Hoffmann, Niklaus Labhardt, Matthias Cavassini, Mathieu Rougemont, Huldrych F Günthard, Olivia Keiser, Andri Rauch, the Swiss HIV Cohort Study

J Infect Dis. 2019 Jul 1; 220(1): 91–99. Published online 2019 Feb 13. doi: 10.1093/infdis/jiz069

PMCID:: PMC6548898

Abstract Article PDF–3.1M

Select item 65209548.

Interpreting Viral Deep Sequencing Data with GLUE

Joshua B. Singer, Emma C. Thomson, Joseph Hughes, Elihu Aranday-Cortes, John McLauchlan, Ana da Silva Filipe, Lily Tong, Carmen F. Manso, Robert J. Gifford, David L. Robertson, Eleanor Barnes, M. Azim Ansari, Jean L. Mbisa, David F. Bibby, Daniel Bradshaw, David Smith

Viruses. 2019 Apr; 11(4): 323. Published online 2019 Apr 3. doi: 10.3390/v11040323

PMCID:: PMC6520954

Abstract Article PDF–671K

Select item 64787439.

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Benjamin G. Barwick, Paola Neri, Nizar J. Bahlis, Ajay K. Nooka, Madhav V. Dhodapkar, David L. Jaye, Craig C. Hofmeister, Jonathan L. Kaufman, Vikas A. Gupta, Daniel Auclair, Jonathan J. Keats, Sagar Lonial, Paula M. Vertino, Lawrence H. Boise

Nat Commun. 2019; 10: 1911. Published online 2019 Apr 23. doi: 10.1038/s41467-019-09555-6

PMCID:: PMC6478743

Abstract Article PDF–9.0M

Select item 645672610.

StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins

Conor L. Jacobs, Ryan K. Badiee, Michael Z. Lin

Nat Methods. Author manuscript; available in PMC 2019 Apr 10.

Published in final edited form as: Nat Methods. 2018 Jul; 15(7): 523–526. Published online 2018 Jul 2. doi: 10.1038/s41592-018-0041-z

PMCID:: PMC6456726

Abstract Article PDF–626K

Select item 645178611.

Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver

Jin Zhang, Xing Gao, Yuan Yuan, Chao Sun, Yuanlin Zhao, Liming Xiao, Ying Yang, Yu Gu, Risheng Yang, Peizhen Hu, Lijun Zhang, Chao Wang, Jing Ye

Lipids Health Dis. 2019; 18: 87. Published online 2019 Apr 6. doi: 10.1186/s12944-019-1022-7

PMCID:: PMC6451786

Abstract Article PDF–4.8M

Select item 643343812.

Infrequent Development of Resistance in Genotype 1–6 Hepatitis C Virus–Infected Subjects Treated With Sofosbuvir in Phase 2 and 3 Clinical Trials

Evguenia S. Svarovskaia, Hadas Dvory-Sobol, Neil Parkin, Christy Hebner, Viktoria Gontcharova, Ross Martin, Wen Ouyang, Bin Han, Simin Xu, Karin Ku, Sophia Chiu, Edward Gane, Ira M. Jacobson, David R. Nelson, Eric Lawitz, David L. Wyles, Neby Bekele, Diana Brainard, William T. Symonds, John G. McHutchison, Michael D. Miller, Hongmei Mo

Clin Infect Dis. 2014 Dec 15; 59(12): 1666–1674. Published online 2014 Sep 28. doi: 10.1093/cid/ciu697

PMCID:: PMC6433438

Abstract Article PDF–220K

Select item 642106713.

Analysis of resistance-associated substitutions in acute hepatitis C virus infection by deep sequencing across six genotypes and three continents.

Auda A. Eltahla, Chaturaka Rodrigo, Brigid Betz-Stablein, Jason Grebely, Tanya Applegate, Fabio Luciani, Janke Schinkel, Gregory J. Dore, Kimberly Page, Julie Bruneau, Meghan D. Morris, Andrea L. Cox, Arthur Y. Kim, Naglaa H. Shoukry, Georg M. Lauer, Lisa Maher, Margaret Hellard, Maria Prins, Andrew R. Lloyd, Rowena A. Bull

J Viral Hepat. Author manuscript; available in PMC 2019 Mar 17.

Published in final edited form as: J Viral Hepat. 2017 Jan; 24(1): 37–42. Published online 2016 Sep 25. doi: 10.1111/jvh.12615

PMCID:: PMC6421067

Abstract Article PDF–1.0M

Select item 637101414.

A latent class approach to identify multi‐risk profiles associated with phylogenetic clustering of recent hepatitis C virus infection in Australia and New Zealand from 2004 to 2015

Sofia R Bartlett, Tanya L Applegate, Brendan P Jacka, Marianne Martinello, Francois MJ Lamoury, Mark Danta, Daniel Bradshaw, David Shaw, Andrew R Lloyd, Margaret Hellard, Gregory J Dore, Gail V Matthews, Jason Grebely

J Int AIDS Soc. 2019 Feb; 22(2): e25222. Published online 2019 Feb 12. doi: 10.1002/jia2.25222

PMCID:: PMC6371014

Abstract Article PDF–866K

Select item 635707715.

Genomic-Scale Interaction Involving Complementary Sequences in the Hepatitis C Virus 5′UTR Domain IIa and the RNA-Dependent RNA Polymerase Coding Region Promotes Efficient Virus Replication

Elodie Rance, Jerome E. Tanner, Caroline Alfieri

Viruses. 2019 Jan; 11(1): 17. Published online 2018 Dec 28. doi: 10.3390/v11010017

PMCID:: PMC6357077

Abstract Article PDF–1.8M

Select item 632814416.

Screening human cell lines for viral infections applying RNA-Seq data analysis

Cord C. Uphoff, Claudia Pommerenke, Sabine A. Denkmann, Hans G. Drexler

PLoS One. 2019; 14(1): e0210404. Published online 2019 Jan 10. doi: 10.1371/journal.pone.0210404

PMCID:: PMC6328144

Abstract Article PDF–1.5M

Select item 629965117.

GLUE: a flexible software system for virus sequence data

Joshua B. Singer, Emma C. Thomson, John McLauchlan, Joseph Hughes, Robert J. Gifford

BMC Bioinformatics. 2018; 19: 532. Published online 2018 Dec 18. doi: 10.1186/s12859-018-2459-9

PMCID:: PMC6299651

Abstract Article PDF–1.4M

Select item 627652618.

Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma

Luca Mercuri, Emma C. Thomson, Joseph Hughes, Peter Karayiannis

Adv Virol. 2018; 2018: 4835252. Published online 2018 Nov 19. doi: 10.1155/2018/4835252

PMCID:: PMC6276526

Abstract Article PDF–1.2M

Select item 620893119.

Prevalence of resistance-associated substitutions to direct-acting antiviral agents in hemodialysis and renal transplant patients infected with hepatitis C virus

Rita Chelly Felix Tavares, Ana Cristina de Castro Amaral Feldner, João Renato Rebello Pinho, Fernanda de Mello Malta, Roberto José Carvalho-Filho, Rúbia Anita Ferraz Santana, Vanessa Fusco Duarte de Castro, Gregório Tadeu Fernando Dastoli, Juliana Custódio Lima, Maria Lucia Cardoso Gomes Ferraz

Infect Drug Resist. 2018; 11: 1993–2000. Published online 2018 Oct 25. doi: 10.2147/IDR.S169512

Correction in:: Infect Drug Resist. 2019; 12: 65.

PMCID:: PMC6208931

Abstract Article PDF–166K

Select item 617092720.

Prevalence and Genotype Distribution of Hepatitis C Virus Infection among Patients with Type 2 Diabetes Mellitus

Fatemeh Farshadpour, Reza Taherkhani, Mohammad Reza Ravanbod, Seyed Sajjad Eghbali

Med Princ Pract. 2018 Sep; 27(4): 308–316. Published online 2018 Apr 5. doi: 10.1159/000488985

PMCID:: PMC6170927

Abstract Article PDF–358K

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