PMC Links for GEO Profiles (Select 100010345) - PMC

Links from GEO Profiles

Items: 1 to 20 of 45

<< First< Prev

Page of 3

Select item 91063031.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 87052992.

Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation

Stephan Kohrt, Sarah Strobel, Melanie C. Mann, Heinrich Sticht, Bernhard Fleckenstein, Andrea K. Thoma-Kress

Int J Mol Sci. 2021 Dec; 22(24): 13597. Published online 2021 Dec 18. doi: 10.3390/ijms222413597

PMCID:: PMC8705299

Abstract Article PDF–4.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79104594.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

Select item 73671845.

Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2

Jun Wu, Yuhua Xue, Xiang Gao, Qiang Zhou

Nucleic Acids Res. 2020 Jul 27; 48(13): 7321–7332. Published online 2020 Jun 1. doi: 10.1093/nar/gkaa461

PMCID:: PMC7367184

Abstract Article PDF–3.8M

Select item 73220676.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67781378.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 65375869.

Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells

Tiejun Yang, Yifeng Jing, Jun Dong, Xinpei Yu, Mingming Zhong, Laura E. Pascal, Dan Wang, Zhongxian Zhang, Baoping Qiao, Zhou Wang

Prostate. Author manuscript; available in PMC 2019 May 28.

Published in final edited form as: Prostate. 2018 Nov; 78(15): 1201–1212. Published online 2018 Jul 15. doi: 10.1002/pros.23695

Correction in:: Prostate. 2020 Feb; 80(2): 238.

PMCID:: PMC6537586

Abstract Article PDF–1.5M

Select item 591702610.

The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression

Mina Ali, Ram Ajore, Anna-Karin Wihlborg, Abhishek Niroula, Bhairavi Swaminathan, Ellinor Johnsson, Owen W Stephens, Gareth Morgan, Tobias Meissner, Ingemar Turesson, Hartmut Goldschmidt, Ulf-Henrik Mellqvist, Urban Gullberg, Markus Hansson, Kari Hemminki, Hareth Nahi, Anders Waage, Niels Weinhold, Björn Nilsson

Nat Commun. 2018; 9: 1649. Published online 2018 Apr 25. doi: 10.1038/s41467-018-04082-2

PMCID:: PMC5917026

Abstract Article PDF–1.4M

Select item 576134011.

ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells

Yachen Zang, Laura E. Pascal, Yibin Zhou, Xiaonan Qiu, Leizhen Wei, Junkui Ai, Joel B. Nelson, Mingming Zhong, Boxin Xue, Shaoxiong Wang, Dongrong Yang, Li Lan, Yuxi Shan, Zhou Wang

Cancer Lett. Author manuscript; available in PMC 2019 Feb 28.

Published in final edited form as: Cancer Lett. 2018 Feb 28; 415: 198–207. Published online 2017 Nov 26. doi: 10.1016/j.canlet.2017.11.028

PMCID:: PMC5761340

Abstract Article PDF–2.4M

Select item 567908412.

Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia

Laura E. Pascal, Khalid Z. Masoodi, June Liu, Xiaonan Qiu, Qiong Song, Yujuan Wang, Yachen Zang, Tiejun Yang, Yao Wang, Lora H. Rigatti, Uma Chandran, Leandro M. Colli, Ricardo Z.N. Vencio, Yi Lu, Jian Zhang, Zhou Wang

J Endocrinol. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: J Endocrinol. 2017 Nov; 235(2): 123–136. doi: 10.1530/JOE-17-0112

PMCID:: PMC5679084

Abstract Article PDF–1.1M

Select item 565344013.

Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival

Lou-Ella M.M Alexander, January Watters, Jessica A. Reusch, Michelle Maurin, Brook S. Nepon-Sixt, Katerina Vrzalikova, Mark G. Alexandrow, Paul G. Murray, Kenneth L. Wright

Mol Immunol. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Mol Immunol. 2017 Nov; 91: 8–16. Published online 2017 Aug 31. doi: 10.1016/j.molimm.2017.08.016

PMCID:: PMC5653440

Abstract Article PDF–711K

Select item 560896914.

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

Ni Li, David C. Johnson, Niels Weinhold, Scott Kimber, Sara E. Dobbins, Jonathan S. Mitchell, Ben Kinnersley, Amit Sud, Philip J. Law, Giulia Orlando, Matthew Scales, Christopher P. Wardell, Asta Försti, Phuc H. Hoang, Molly Went, Amy Holroyd, Fadi Hariri, Tomi Pastinen, Tobias Meissner, Hartmut Goldschmidt, Kari Hemminki, Gareth J. Morgan, Martin Kaiser, Richard S. Houlston

Cell Rep. 2017 Sep 12; 20(11): 2556–2564. Published online 2017 Sep 12. doi: 10.1016/j.celrep.2017.08.062

PMCID:: PMC5608969

Abstract Article

Select item 560692915.

NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation

Christiane Trimpert, Daniel Wesche, Theun de Groot, Martha M. Pimentel Rodriguez, Victoria Wong, Dennis T. M. van den Berg, Lydie Cheval, Carolina A. Ariza, Alain Doucet, Igor Stagljar, Peter M. T. Deen

PLoS One. 2017; 12(9): e0183774. Published online 2017 Sep 20. doi: 10.1371/journal.pone.0183774

PMCID:: PMC5606929

Abstract Article PDF–7.0M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 545599617.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

Cell Syst. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001