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Items: 1 to 20 of 73

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome
Xiao-Yue Chen, Ching Kao, Syue-Wei Peng, Jer-Hwa Chang, Yueh-Lun Lee, Vincent Laiman, Kian Fan Chung, Pankaj K. Bhavsar, Didik Setyo Heriyanto, Kai-Jen Chuang, Hsiao-Chi Chuang
Mol Med. 2023; 29: 159. Published online 2023 Nov 23. doi: 10.1186/s10020-023-00760-0
PMCID:
PMC10668445
AbstractArticlePDF–4.6M
3.
Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway
Bin Yang, Yunjie Zhao, Wu Luo, Weiwei Zhu, Leiming Jin, Minxiu Wang, Lin Ye, Yi Wang, Guang Liang
Cell Death Dis. 2023 Jul; 14(7): 419. Published online 2023 Jul 13. doi: 10.1038/s41419-023-05960-4
PMCID:
PMC10345119
AbstractArticlePDF–7.0M
4.
Doublecortin-like kinase 1 (DCLK1) Facilitates Dendritic Spine Growth of Pyramidal Neurons in Mouse Prefrontal Cortex
Kelsey E. Murphy, Erin Y. Zhang, Elliott V. Wyatt, Justin E. Sperringer, Bryce W. Duncan, Patricia F. Maness
Neuroscience. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Neuroscience. 2023 Jan 1; 508: 98–109. Published online 2022 Sep 3. doi: 10.1016/j.neuroscience.2022.08.020
PMCID:
PMC10317307
AbstractArticlePDF–1.5M
5.
TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine
Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova
Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452
PMCID:
PMC10253002
AbstractArticlePDF–2.4M
6.
Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses
Zhuqi Huang, Sirui Shen, Xue Han, Weixin Li, Wu Luo, Liming Lin, Mingjiang Xu, Yi Wang, Weijian Huang, Gaojun Wu, Guang Liang
EMBO Mol Med. 2023 May; 15(5): e17198. Published online 2023 Mar 10. doi: 10.15252/emmm.202217198
PMCID:
PMC10165355
AbstractArticlePDF–3.6M
7.
Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ
Wu Luo, Yiyi Jin, Yuchen Jiang, Libin Yang, Haowen Xu, Di Wu, Yanmei Zhang, Lina Yin, Zia Ali Khan, Guang Liang, Yi Wang
Cell Death Differ. 2023 May; 30(5): 1184–1197. Published online 2023 Mar 13. doi: 10.1038/s41418-023-01147-8
PMCID:
PMC10154386
AbstractArticlePDF–6.3M
8.
Doublecortin-like kinases promote neuronal survival and induce growth cone reformation via distinct mechanisms
Homaira Nawabi, Stephane Belin, Romain Cartoni, Philip R. Williams, Chen Wang, Alban Latremolière, Xuhua Wang, Junjie Zhu, Daniel G Taub, Xiaoqin Fu, Bin Yu, Xiaosong Gu, Clifford J. Woolf, Judy S. Liu, Christopher V. Gabel, Judith A. Steen, Zhigang He
Neuron. Author manuscript; available in PMC 2023 Apr 3.
Published in final edited form as: Neuron. 2015 Nov 18; 88(4): 704–719. Published online 2015 Oct 29. doi: 10.1016/j.neuron.2015.10.005
PMCID:
PMC10069300
AbstractArticlePDF–2.2M
9.
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis
Jee-Heun Kim, So-Yeon Park, So-El Jeon, Jang-Hyun Choi, Choong-Jae Lee, Tae-Young Jang, Hyeon-Ji Yun, Yuno Lee, Pilho Kim, Sang Hee Cho, Ji Shin Lee, Jeong-Seok Nam
Theranostics. 2022; 12(12): 5258–5271. Published online 2022 Jul 4. doi: 10.7150/thno.72037
PMCID:
PMC9330537
AbstractArticlePDF–3.8M
10.
Doublecortin‐like expressing astrocytes of the suprachiasmatic nucleus are implicated in the biosynthesis of vasopressin and influences circadian rhythms
Claudia Coomans, Dirk‐Jan Saaltink, Tom Deboer, Mayke Tersteeg, Suzanne Lanooij, Anne Fleur Schneider, Aat Mulder, Jan van Minnen, Carolina Jost, Abraham J. Koster, Erno Vreugdenhil
Glia. 2021 Nov; 69(11): 2752–2766. Published online 2021 Aug 3. doi: 10.1002/glia.24069
PMCID:
PMC9291169
AbstractArticlePDF–18M
11.
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Yang Ge, Nathaniel Weygant, Dongfeng Qu, Randal May, William L. Berry, Jiannan Yao, Parthasarathy Chandrakesan, Wei Zheng, Lichao Zhao, Karena L. Zhao, Michael Drake, Kenneth J. Vega, Michael S. Bronze, James J. Tomasek, Guangyu An, Courtney W. Houchen
Int J Cancer. Author manuscript; available in PMC 2021 Aug 25.
Published in final edited form as: Int J Cancer. 2018 Sep 1; 143(5): 1162–1175. Published online 2018 Apr 16. doi: 10.1002/ijc.31400
PMCID:
PMC8386112
AbstractArticlePDF–2.7M
12.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
13.
Notch signaling drives development of Barrett’s metaplasia from Dclk1-positive epithelial tuft cells in the murine gastric mucosa
Bettina Kunze, Moritz Middelhoff, H. Carlo Maurer, Tatiana Agibalova, Akanksha Anand, Anne-Marie Bührer, Hsin-Yu Fang, Theresa Baumeister, Katja Steiger, Julia Strangmann, Roland M. Schmid, Timothy C. Wang, Michael Quante
Sci Rep. 2021; 11: 4509. Published online 2021 Feb 24. doi: 10.1038/s41598-021-84011-4
PMCID:
PMC7904766
AbstractArticlePDF–5.0M
14.
Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
Takahisa Maruno, Akihisa Fukuda, Norihiro Goto, Motoyuki Tsuda, Kozo Ikuta, Yukiko Hiramatsu, Satoshi Ogawa, Yuki Nakanishi, Yuichi Yamaga, Takuto Yoshioka, Kyoichi Takaori, Shinji Uemoto, Dieter Saur, Tsutomu Chiba, Hiroshi Seno
eLife. 2021; 10: e55117. Published online 2021 Jan 4. doi: 10.7554/eLife.55117
PMCID:
PMC7800378
AbstractArticlePDF–9.1M
15.
Doublecortin-Like Is Implicated in Adult Hippocampal Neurogenesis and in Motivational Aspects to Escape from an Aversive Environment in Male Mice
Dirk-Jan Saaltink, Erik W. van Zwet, Erno Vreugdenhil
eNeuro. 2020 Sep-Oct; 7(5): ENEURO.0324-19.2020. Prepublished online 2020 Sep 29. Published online 2020 Oct 14. doi: 10.1523/ENEURO.0324-19.2020
PMCID:
PMC7568604
AbstractArticlePDF–1.7M
16.
Tuft cell-derived leukotrienes drive rapid anti-helminth immunity in the small intestine but are dispensable for anti-protist immunity
John W. McGinty, Hung-An Ting, Tyler E. Billipp, Marija S. Nadjsombati, Danish M. Khan, Nora A. Barrett, Hong-Erh Liang, Ichiro Matsumoto, Jakob von Moltke
Immunity. Author manuscript; available in PMC 2020 Sep 17.
Published in final edited form as: Immunity. 2020 Mar 17; 52(3): 528–541.e7. Published online 2020 Mar 10. doi: 10.1016/j.immuni.2020.02.005
PMCID:
PMC7469474
AbstractArticlePDF–1.1M
17.
LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome
Huaying Wang, Jianming Wang, Yuhan Zhao, Xiao Zhang, Juan Liu, Cen Zhang, Bruce Haffty, Michael Verzi, Lanjing Zhang, Nan Gao, Zhaohui Feng, Wenwei Hu
Cell Death Dis. 2020 Jul; 11(7): 588. Published online 2020 Jul 27. doi: 10.1038/s41419-020-02790-6
PMCID:
PMC7385639
AbstractArticlePDF–8.8M
18.
Functional analysis of candidate genes from genome-wide association studies of hearing
Neil J. Ingham, Victoria Rook, Francesca Di Domenico, Elysia James, Morag A. Lewis, Giorgia Girotto, Annalisa Buniello, Karen P. Steel
Hear Res. 2020 Mar 1; 387: 107879. doi: 10.1016/j.heares.2019.107879
PMCID:
PMC6996162
AbstractArticlePDF–9.5M
19.
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity
Gabriel E. Vázquez-Vélez, Kristyn A. Gonzales, Jean-Pierre Revelli, Carolyn J. Adamski, Fatemeh Alavi Naini, Aleksandar Bajić, Evelyn Craigen, Ronald Richman, Sabrina M. Heman-Ackah, Matthew J.A. Wood, Maxime W.C. Rousseaux, Huda Y. Zoghbi
J Neurosci. 2020 Jan 8; 40(2): 459–477. doi: 10.1523/JNEUROSCI.1076-19.2019
PMCID:
PMC6948939
AbstractArticlePDF–9.4M
20.
DCAMKL1 Encodes a Protein Kinase with Homology to Doublecortin that Regulates Microtubule Polymerization
Peter T. Lin, Joseph G. Gleeson, Joseph C. Corbo, Lisa Flanagan, Christopher A. Walsh
J Neurosci. 2000 Dec 15; 20(24): 9152–9161. doi: 10.1523/JNEUROSCI.20-24-09152.2000
PMCID:
PMC6773030
AbstractArticlePDF–926K

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